Xilio Therapeutics (XLO) Short Interest Ratio & Short Volume $0.70 -0.02 (-3.15%) As of 12:25 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock Xilio Therapeutics Short Interest DataXilio Therapeutics (XLO) has a short interest of 4.31 million shares, representing 23.46% of the float (the number of shares available for trading by the public). This marks a 12.83% increase in short interest from the previous month. The short interest ratio (days to cover) is 7.5, indicating that it would take 7.5 days of the average trading volume of 1.99 million shares to cover all short positions.Current Short Interest4,310,000 sharesPrevious Short Interest3,820,000 sharesChange Vs. Previous Month+12.83%Dollar Volume Sold Short$3.06 millionShort Interest Ratio7.5 Days to CoverLast Record DateAugust 15, 2025Outstanding Shares51,830,000 sharesFloat Size18,370,000 sharesShort Percent of Float23.46%Today's Trading Volume96,422 sharesAverage Trading Volume1,988,558 sharesToday's Volume Vs. Average5% Short Selling Xilio Therapeutics? Sign up to receive the latest short interest report for Xilio Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Get Report View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartXLO Short Interest Over TimeXLO Days to Cover Over TimeXLO Percentage of Float Shorted Over Time Xilio Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 8/15/20254,310,000 shares $3.06 million +12.8%23.5%7.5 $0.71 7/31/20253,820,000 shares $2.48 million +14.4%21.3%2.9 $0.65 7/15/20253,340,000 shares $2.38 million -58.8%18.6%2.7 $0.71 6/30/20258,110,000 shares $5.51 million +209.5%16.5%1.3 $0.68 6/15/20252,620,000 shares $1.74 million +231.0%16.1%2.1 $0.66 5/31/2025791,500 shares $893.60 thousand -35.1%4.8%0.6 $1.13 5/15/20251,220,000 shares $976 thousand +247.4%7.4%1.1 $0.80 4/30/2025351,200 shares $268.91 thousand -37.5%2.2%0.1 $0.77 4/15/2025562,300 shares $400.36 thousand -12.8%3.6%0.2 $0.71 3/31/2025644,500 shares $466.88 thousand +12.0%3.9%0.2 $0.72 Get the Latest News and Ratings for XLO and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Xilio Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 3/15/2025575,500 shares $460.52 thousand -17.2%3.5%0.1 $0.80 2/28/2025694,600 shares $629.31 thousand -61.6%4.7%0.2 $0.91 2/15/20251,810,000 shares $2.06 million +809.1%10.7%0.5 $1.14 1/31/2025199,100 shares $140.37 thousand -6.6%1.0%0.4 $0.71 1/15/2025213,100 shares $230.15 thousand -44.5%1.1%0.4 $1.08 12/31/2024384,100 shares $366.82 thousand +221.7%2.1%0.8 $0.96 12/15/2024119,400 shares $115.67 thousand -31.9%0.6%0.3 $0.97 11/30/2024175,300 shares $191.08 thousand +317.4%0.9%0.7 $1.09 11/15/202442,000 shares $43.68 thousand -89.4%0.2%0.2 $1.04 10/31/2024396,100 shares $503.05 thousand +278.0%1.9%1.6 $1.27 10/15/2024104,800 shares $83.84 thousand -25.2%0.5%0.7 $0.80 9/30/2024140,100 shares $110.36 thousand +846.6%0.7%1 $0.79 9/15/202414,800 shares $12.14 thousand -52.3%0.1%0.1 $0.82 8/31/202431,000 shares $26.59 thousand -72.2%0.1%0.2 $0.86 8/15/2024111,300 shares $92.38 thousand -6.2%0.5%0.5 $0.83 7/31/2024118,600 shares $112.65 thousand -18.2%0.6%0.5 $0.95 7/15/2024144,900 shares $146.35 thousand +23.1%0.7%0.5 $1.01 6/30/2024117,700 shares $111.52 thousand +56.9%0.6%0.3 $0.95 6/15/202475,000 shares $76.50 thousand -83.2%0.4%0.1 $1.02 5/31/2024445,000 shares $480.60 thousand +6.2%2.2%0.3 $1.08 5/15/2024419,100 shares $469.39 thousand -8.2%2.0%0.3 $1.12 4/30/2024456,500 shares $474.76 thousand +20.3%5.2%0.4 $1.04 4/15/2024379,500 shares $478.17 thousand +600.2%4.4%0.3 $1.26 3/31/202454,200 shares $58.54 thousand -5.9%0.7%0 $1.08 3/15/202457,600 shares $39.46 thousand +171.7%0.4%0.3 $0.69 2/29/202421,200 shares $15.03 thousand -37.3%0.2%0.1 $0.71 2/15/202433,800 shares $19.85 thousand +2,012.5%0.2%0.2 $0.59 1/31/20241,600 shares $1.04 thousand -75.4%0.0%0 $0.65 1/15/20246,500 shares $4.83 thousand +364.3%0.1%0 $0.74 12/31/20231,400 shares $770.00 -92.5%0.0%0 $0.55 12/15/202318,600 shares $13.21 thousand -65.6%0.1%0.4 $0.71 11/30/202354,100 shares $51.40 thousand +86.6%0.4%2.2 $0.95 11/15/202329,000 shares $38.86 thousand +14.6%0.2%1.5 $1.34 10/31/202325,300 shares $54.40 thousand -4.5%0.2%1.7 $2.15 10/15/202326,500 shares $46.38 thousand +7.7%0.2%2.2 $1.75 9/30/202324,600 shares $51.91 thousand +98.4%0.2%2.1 $2.11 9/15/202312,400 shares $29.26 thousand -77.0%0.1%1.1 $2.36 8/31/202353,900 shares $154.69 thousand -2.7%0.4%4 $2.87 8/15/202355,400 shares $151.24 thousand -7.1%0.4%4.2 $2.73 7/31/202359,600 shares $170.46 thousand -23.6%0.4%4.1 $2.86 7/15/202378,000 shares $206.70 thousand -4.5%0.6%4.9 $2.65 6/30/202381,700 shares $214.05 thousand -46.2%0.6%3.6 $2.62 6/15/2023151,800 shares $414.41 thousand -21.4%1.2%6.5 $2.73 5/31/2023193,100 shares $588.96 thousand -3.3%1.5%8.9 $3.05 5/15/2023199,600 shares $612.77 thousand +1.0%1.7%7.6 $3.07 4/30/2023197,600 shares $652.08 thousand -12.1%1.8%7 $3.30 4/15/2023224,700 shares $741.51 thousand +25.7%2.0%4.3 $3.30 3/31/2023178,700 shares $566.48 thousand +58.6%1.6%3.4 $3.17 3/15/2023112,700 shares $311.05 thousand +160.9%1.0%2.2 $2.76 2/28/202343,200 shares $155.95 thousand +77.1%0.4%0.9 $3.61 2/15/202324,400 shares $77.59 thousand -62.6%0.3%0.5 $3.18 1/31/202365,200 shares $237.98 thousand +239.6%0.7%1.3 $3.65 1/15/202319,200 shares $51.07 thousand -31.4%0.2%0.5 $2.66 12/30/202228,000 shares $75.32 thousand +1.8%0.3%1 $2.69 12/15/202227,500 shares $62.70 thousand -0.7%0.3%0.9 $2.28 11/30/202227,700 shares $67.03 thousand +12.2%0.3%0.3 $2.42 11/15/202224,700 shares $59.28 thousand +34.2%0.3%0.3 $2.40 10/31/202218,400 shares $43.06 thousand -41.4%0.2%0.2 $2.34 10/15/202231,400 shares $72.22 thousand -34.0%0.3%0.3 $2.30 9/30/202247,600 shares $138.52 thousand -15.3%0.5%0.4 $2.91 9/15/202256,200 shares $177.03 thousand +72.4%0.6%0.4 $3.15 8/31/202232,600 shares $73.02 thousand -45.4%0.3%0.3 $2.24 8/15/202259,700 shares $146.27 thousand +114.8%0.6%0.5 $2.45 7/31/202227,800 shares $80.62 thousand -48.1%0.3%0.2 $2.90 7/15/202253,600 shares $165.62 thousand -31.9%0.5%0.5 $3.09 6/30/202278,700 shares $229.80 thousand -65.4%0.8%0.7 $2.92 6/15/2022227,400 shares $518.47 thousand -31.0%2.3%2.8 $2.28 5/31/2022329,400 shares $988.20 thousand -3.1%3.3%5.8 $3.00 5/15/2022339,800 shares $1.15 million +4.2%3.4%8.7 $3.37 4/30/2022326,200 shares $1.15 million +47.0%3.3%9.5 $3.53 4/15/2022221,900 shares $1.34 million -8.0%2.3%6.7 $6.04 3/31/2022241,200 shares $1.71 million +1.9%2.6%8.8 $7.07 3/15/2022236,700 shares $1.66 million +3.4%2.5%6.4 $7.01 2/28/2022228,900 shares $2.70 million -3.6%2.5%2.7 $11.78 2/15/2022237,400 shares $3.45 million -4.8%2.6%2.5 $14.54 1/31/2022249,400 shares $3.39 million -14.9%2.6%2.3 $13.61 1/15/2022292,900 shares $4.25 million -26.9%3.0%2.3 $14.52 12/31/2021400,900 shares $6.41 million No ChangeN/A2.3 $16.00 XLO Short Interest - Frequently Asked Questions What is Xilio Therapeutics' current short interest? Short interest is the volume of Xilio Therapeutics shares that have been sold short but have not yet been covered or closed out. As of August 15th, traders have sold 4,310,000 shares of XLO short. 23.46% of Xilio Therapeutics' shares are currently sold short. Learn More on Xilio Therapeutics' current short interest. What is a good short interest ratio for Xilio Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. XLO shares currently have a short interest ratio of 8.0. Learn More on Xilio Therapeutics's short interest ratio. What is a good short interest percentage for Xilio Therapeutics? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 23.46% of Xilio Therapeutics' floating shares are currently sold short. Is Xilio Therapeutics' short interest increasing or decreasing? Xilio Therapeutics saw a increase in short interest during the month of August. As of August 15th, there was short interest totaling 4,310,000 shares, an increase of 12.8% from the previous total of 3,820,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. What is Xilio Therapeutics' float size? Xilio Therapeutics currently has issued a total of 51,830,000 shares. Some of Xilio Therapeutics' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Xilio Therapeutics currently has a public float of 18,370,000 shares. How does Xilio Therapeutics' short interest compare to its competitors? 23.46% of Xilio Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Xilio Therapeutics: Cellectis S.A. (0.51%), Cardiff Oncology, Inc. (23.60%), Forte Biosciences, Inc. (0.96%), Coherus Oncology, Inc. (28.16%), Inhibikase Therapeutics, Inc. (4.58%), Zura Bio Limited (1.33%), Cabaletta Bio, Inc. (6.90%), Compugen Ltd. (1.01%), Genelux Corporation (6.71%), Protalix BioTherapeutics, Inc. (4.72%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: Lucid Group, Inc. ($8.00 billion), Spotify Technology ($5.48 billion), AppLovin Corporation ($5.11 billion), Reddit Inc. ($5.02 billion), Coinbase Global, Inc. ($3.99 billion), Charter Communications, Inc. ($3.89 billion), Live Nation Entertainment, Inc. ($3.18 billion), Seagate Technology Holdings PLC ($2.59 billion), ResMed Inc. ($2.55 billion), and Rocket Lab Corporation ($2.52 billion). View all of the most shorted stocks. What does it mean to sell short Xilio Therapeutics stock? Short selling XLO is an investing strategy that aims to generate trading profit from Xilio Therapeutics as its price is falling. XLO shares are trading down $0.01 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Xilio Therapeutics? A short squeeze for Xilio Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of XLO, which in turn drives the price of the stock up even further. How often is Xilio Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including XLO, twice per month. The most recent reporting period available is August, 15 2025. More Short Interest Resources from MarketBeat Related Companies Cellectis Short Squeeze Cardiff Oncology Short Squeeze Forte Biosciences Short Squeeze Coherus Oncology Short Squeeze Inhibikase Therapeutics Short Squeeze Zura Bio Short Squeeze Cabaletta Bio Short Squeeze Compugen Short Squeeze Genelux Short Squeeze Protalix BioTherapeutics Short Squeeze Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:XLO) was last updated on 9/4/2025 by MarketBeat.com Staff From Our PartnersCritical AI announcement set to ignite AI 2.0I just put together an urgent new presentation that you need to see right away. 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