Go Pro
→ How Long Does $2.5M Last in Retirement? (From SmartAsset) (Ad)tc pixel Free PYXS Stock Alerts

Pyxis Oncology (PYXS) Short Interest Ratio & Short Volume

Pyxis Oncology logo
$3.57 -0.18 (-4.80%)
As of 09/3/2026 04:00 PM Eastern
Compare

Pyxis Oncology Short Interest Overview

As of August 14, 2026, Pyxis Oncology (PYXS) had a short interest of 4.43 million shares sold short, representing 5.63% of the public float. This marks a 6.07% increase in short interest since the prior report. The short interest ratio (days to cover) is 2.0, meaning it would take 2.0 days of the average trading volume of 1.37 million shares to cover all short positions.

Current Short Interest
4,425,542 shares
Previous Short Interest
4,172,154 shares
Change Vs. Previous Month
6.07%
Dollar Volume Sold Short
$13.32 million
Short Interest Ratio
2.0 Days to Cover
Last Record Date
August 14, 2026
Outstanding Shares
83,410,000 shares
Short Percent of Float
5.63%
Today's Trading Volume
812,150 shares
Average Trading Volume
1,365,118 shares
Today's Volume Vs. Average
59%
Short Selling Pyxis Oncology?
A Guide To High-Short-Interest Stocks

Sign up to receive the latest short interest report for Pyxis Oncology and its competitors with MarketBeat's FREE newsletter.

Get Report
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.
Skip Charts & View Short Interest History
Short Interest ChartDays to Cover ChartShort Percent of Float Chart

PYXS Short Interest Over Time

PYXS Days to Cover Over Time

PYXS Percentage of Float Shorted Over Time

Pyxis Oncology Tesla Short Interest History & Recent Changes

Export
Report DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date
8/14/20264,425,542 shares $13.32 million +6.1%5.6%1.99 $3.01
7/31/20264,172,154 shares $11.06 million +28.2%7.0%4.19 $2.65
7/15/20263,253,653 shares $7.91 million +42.1%5.4%3.11 $2.43
6/30/20262,289,798 shares $6.89 million +13.6%3.8%1.25 $3.01
6/15/20262,015,710 shares $3.51 million +15.7%3.4%4.85 $1.74
5/29/20261,741,743 shares $3.14 million -3.8%3.1%2.87 $1.80
5/15/20261,809,793 shares $4.13 million -8.9%3.2%2.11 $2.28
4/30/20261,986,201 shares $3.38 million -12.5%3.5%5.51 $1.70
4/15/20262,269,065 shares $3.88 million -14.7%3.8%5.64 $1.71
3/31/20262,660,931 shares $3.88 million +6.9%4.5%7.37 $1.46
3/13/20262,490,249 shares $3.83 million -1.4%4.5%7.7 $1.54
2/27/20262,525,155 shares $3.71 million +3.4%4.5%9.85 $1.47
2/13/20262,442,905 shares $3.18 million +2.4%4.1%3.78 $1.30
1/30/20262,386,094 shares $3.46 million +3.4%4.3%3.94 $1.45
1/15/20262,307,831 shares $4.25 million +33.1%4.1%1.2 $1.84
12/31/20251,733,403 shares $1.99 million -10.3%3.1%0.6 $1.15
12/15/20251,933,041 shares $8.12 million -57.3%3.5%3 $4.20
11/28/20254,523,744 shares $19.00 million -0.4%8.1%7.66 $4.20
11/14/20254,541,093 shares $19.80 million +4.1%8.2%4.79 $4.36
10/31/20254,361,521 shares $15.53 million +2.6%7.8%7.79 $3.56
10/15/20254,250,000 shares $15.56 million +2.9%9.6%6.1 $3.66
9/30/20254,130,000 shares $9.17 million -5.3%9.4%6.5 $2.22
9/15/20254,360,000 shares $8.28 million +0.7%9.9%6.6 $1.90
8/31/20254,330,000 shares $5.54 million -13.9%9.8%7.2 $1.28
8/15/20255,030,000 shares $6.19 million +7.0%11.4%9.5 $1.23
7/31/20254,700,000 shares $5.26 million -1.7%10.7%9.4 $1.12
7/15/20254,780,000 shares $5.54 million -5.5%10.9%8.6 $1.16
6/30/20255,060,000 shares $5.57 million -18.1%11.5%9.1 $1.10
6/15/20256,180,000 shares $7.42 million -4.5%14.0%13.3 $1.20
5/31/20256,470,000 shares $7.83 million -8.2%14.7%13.3 $1.21
5/15/20257,050,000 shares $7.83 million -2.5%16.0%13 $1.11
4/30/20257,230,000 shares $7.95 million +1.4%16.4%12.3 $1.10
4/15/20257,130,000 shares $6.52 million -2.9%16.3%12.4 $0.92
3/31/20257,340,000 shares $7.19 million +6.1%16.8%12.3 $0.98
3/15/20256,920,000 shares $7.68 million -1.3%15.8%10.5 $1.11
2/28/20257,010,000 shares $8.34 million +1.9%16.6%9.1 $1.19
2/15/20256,880,000 shares $9.08 million -1.7%16.3%5.3 $1.32
1/31/20257,000,000 shares $10.99 million -5.7%17.0%5.5 $1.57
1/15/20257,420,000 shares $10.91 million +1.1%18.0%5.9 $1.47
12/31/20247,340,000 shares $11.45 million +14.7%17.9%5.8 $1.56
This sub-5 dollar stock operates next to SpaceX and Blue Origin (Ad)

A small public company trading under $5 a share operates inside the secure perimeter of Kennedy Space Center, right alongside SpaceX and Blue Origin. It holds a special agreement to use a multi-billion dollar federal launch facility for just $500, and its customer list already includes the Pentagon, Lockheed Martin, and GE Aerospace. Most Wall Street analysts have not caught on yet, but a major milestone could change that soon.tc pixel

Click here to see the company behind the gates
12/15/20246,400,000 shares $10.37 million +5.3%15.6%5.2 $1.62
11/30/20246,080,000 shares $12.22 million +4.1%14.8%5.2 $2.01
11/15/20245,840,000 shares $24.47 million -0.3%13.3%6.1 $4.19
10/31/20245,860,000 shares $20.86 million +19.4%13.3%11.6 $3.56
10/15/20244,910,000 shares $15.91 million +16.4%10.5%10.2 $3.24
9/30/20244,220,000 shares $15.49 million +11.9%9.0%8.7 $3.67
9/15/20243,770,000 shares $14.25 million -1.1%8.1%6.1 $3.78
8/31/20243,810,000 shares $14.44 million -5.2%8.2%6.5 $3.79
8/15/20244,020,000 shares $13.79 million +0.8%8.7%6.9 $3.43
7/31/20243,990,000 shares $15.64 million +13.4%8.4%6.9 $3.92
7/15/20243,520,000 shares $11.26 million +52.4%7.4%6.1 $3.20
6/30/20242,310,000 shares $7.65 million No Change4.9%4.2 $3.31
6/15/20242,310,000 shares $8.75 million +5.5%4.9%4.5 $3.79
5/31/20242,190,000 shares $8.19 million +11.7%4.6%3.8 $3.74
5/15/20241,960,000 shares $8.25 million +6.0%4.2%2.9 $4.21
4/30/20241,850,000 shares $8.23 million -16.3%4.0%2.5 $4.45
4/15/20242,210,000 shares $10.48 million -18.2%4.8%2.4 $4.74
3/31/20242,700,000 shares $11.50 million +65.6%6.9%3.1 $4.26
3/15/20241,630,000 shares $8.35 million +21.6%5.3%2.1 $5.12
2/29/20241,340,000 shares $8.52 million +4.7%4.4%2 $6.36
2/15/20241,280,000 shares $7.16 million +63.1%4.2%2.2 $5.59
1/31/2024784,600 shares $2.99 million +28.4%2.6%2 $3.81
1/15/2024611,100 shares $1.44 million -3.6%2.0%3.2 $2.35
12/31/2023634,000 shares $1.14 million -6.0%2.1%4.4 $1.80
12/15/2023674,600 shares $1.17 million -9.6%2.2%5.3 $1.73
11/30/2023745,800 shares $1.19 million -6.9%2.5%5.8 $1.59
11/15/2023801,100 shares $1.22 million +1.1%2.7%6.4 $1.52
10/31/2023792,500 shares $1.32 million -9.7%2.6%5.9 $1.67
10/15/2023877,300 shares $1.75 million -6.9%2.9%5.8 $2.00
9/30/2023942,400 shares $1.88 million +3.6%3.1%5.3 $1.99
9/15/2023910,100 shares $1.92 million -5.1%3.0%4.2 $2.11
8/31/2023958,600 shares $2.09 million -15.2%3.0%4 $2.18
8/15/20231,130,000 shares $2.76 million -2.6%3.9%3.9 $2.44
7/31/20231,160,000 shares $2.99 million -4.1%4.3%3.1 $2.58
7/15/20231,210,000 shares $3.21 million -60.2%4.5%2.7 $2.65
6/30/20233,040,000 shares $7.78 million -3.5%11.3%4.9 $2.56
6/15/20233,150,000 shares $9.51 million No Change11.7%0.8 $3.02
5/31/20233,150,000 shares $10.14 million +2.6%11.9%0.8 $3.22
5/15/20233,070,000 shares $11.45 million -14.7%11.6%0.8 $3.73
4/30/20233,600,000 shares $10.62 million -23.7%17.9%1 $2.95
4/15/20234,720,000 shares $16.38 million -2.7%23.4%1.3 $3.47
3/31/20234,850,000 shares $19.45 million +5,962.5%25.0%1.4 $4.01
3/15/202380,000 shares $160.80 thousand -52.3%0.4%0.5 $2.01
2/28/2023167,700 shares $380.68 thousand +49.6%0.8%1.4 $2.27
2/15/2023112,100 shares $173.76 thousand -88.5%0.6%0.7 $1.55
1/31/2023973,800 shares $1.52 million +2.8%4.8%5.4 $1.56
1/15/2023947,200 shares $1.45 million +14.7%4.7%5.9 $1.53
12/30/2022826,200 shares $1.11 million +35.7%4.1%4.8 $1.34
12/15/2022609,000 shares $694.26 thousand +110.1%3.0%3.7 $1.14
11/30/2022289,800 shares $420.21 thousand +80.5%1.4%2 $1.45
Man who Predicted Trump 2016 Win: “Prepare for Mid-Term Meltdown” (Ad)

In 2016, major election models gave Hillary Clinton a 99% chance of winning - but former CIA and Pentagon adviser Jim Rickards publicly predicted a Trump victory before election night. Now Rickards is issuing a new forecast he calls a potential mid-term meltdown, one he believes could send shockwaves through financial markets.tc pixel

See Jim Rickards' full market warning and what it means for your portfolio
11/15/2022160,600 shares $234.48 thousand +286.1%0.8%2.1 $1.46
10/31/202241,600 shares $77.79 thousand -54.8%0.2%0.7 $1.87
10/15/202292,100 shares $155.65 thousand -13.3%0.5%2 $1.69
9/30/2022106,200 shares $209.21 thousand -3.1%0.5%2.4 $1.97
9/15/2022109,600 shares $260.85 thousand +34.6%0.5%1.1 $2.38
8/31/202281,400 shares $210.83 thousand -26.7%0.4%0.8 $2.59
8/15/2022111,000 shares $309.69 thousand -7.7%0.5%0.7 $2.79
7/31/2022120,300 shares $318.80 thousand -6.7%0.5%0.6 $2.65
7/15/2022128,900 shares $382.83 thousand -7.3%0.6%0.6 $2.97
6/30/2022139,000 shares $330.82 thousand -69.0%0.6%0.5 $2.38
6/15/2022448,000 shares $1.04 million -6.6%2.0%1.8 $2.33
5/31/2022479,800 shares $1.19 million +37.9%2.2%2.3 $2.47
5/15/2022347,900 shares $702.76 thousand +1.4%1.6%2.1 $2.02
4/30/2022343,200 shares $840.84 thousand -18.6%1.6%3.3 $2.45
4/15/2022421,500 shares $1.54 million -21.7%2.1%4.1 $3.65
3/31/2022538,500 shares $2.18 million +12.0%2.6%6.9 $4.04
3/15/2022480,700 shares $2.19 million +0.7%2.0%6.7 $4.55
2/28/2022477,500 shares $2.90 million -2.4%2.0%3.7 $6.08
2/15/2022489,400 shares $3.85 million +6.3%2.0%3.6 $7.86
1/31/2022460,300 shares $4.39 million +27.9%1.9%3.1 $9.54
1/15/2022359,800 shares $3.71 million -34.7%1.5%2.3 $10.30
12/31/2021551,200 shares $6.05 million No Change2.3%2.7 $10.97

PYXS Short Interest - Frequently Asked Questions

Short interest is the volume of Pyxis Oncology shares that have been sold short but have not yet been covered or closed out. As of August 14th, investors have sold 4,425,542 shares of PYXS short. 5.63% of Pyxis Oncology's shares are currently sold short. Learn More on Pyxis Oncology's current short interest.

The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. PYXS shares currently have a short interest ratio of 2.0. Learn More on Pyxis Oncology's short interest ratio.

Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 5.63% of Pyxis Oncology's floating shares are currently sold short.

Pyxis Oncology saw a increase in short interest in August. As of August 14th, there was short interest totaling 4,425,542 shares, an increase of 6.1% from the previous total of 4,172,154 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment.

5.63% of Pyxis Oncology's shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Pyxis Oncology: Geron Corporation (12.76%), Design Therapeutics, Inc. (11.42%), Annexon, Inc. (19.16%), Olema Pharmaceuticals, Inc. (20.66%), DBV Technologies S.A. (2.63%), Aclaris Therapeutics, Inc. (11.05%), Sensei Biotherapeutics, Inc. (3.44%), 4D Molecular Therapeutics, Inc. (24.15%), Rigel Pharmaceuticals, Inc. (19.34%), Neurogene Inc. (17.19%),

As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($71.57 billion), Invesco QQQ ($46.97 billion), iShares Russell 2000 ETF ($24.02 billion), Nebius Group N.V. ($15.37 billion), Sandisk Corporation ($12.60 billion), SPDR S&P Biotech ETF ($12.14 billion), Western Digital Corporation ($10.32 billion), iShares 20+ Year Treasury Bond ETF ($8.38 billion), VanEck Semiconductor ETF ($7.62 billion), and iShares iBoxx $ High Yield Corporate Bond ETF ($7.07 billion). View all of the most shorted stocks.

Short selling PYXS is an investing strategy that aims to generate trading profit from Pyxis Oncology as its price is falling. PYXS shares are trading down $0.18 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit.

A short squeeze for Pyxis Oncology occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of PYXS, which in turn drives the price of the stock up even further.

Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including PYXS, twice per month. The most recent reporting period available is August, 14 2026.

Understanding short interest metrics can help you assess how traders are positioning around a stock like PYXS:

  • Shares Sold Short: The total number of shares that have been sold by short sellers but have not yet been covered or closed out. A high number may indicate bearish sentiment.
  • Short Float: The percentage of a company’s publicly available shares (or "float") that are sold short. A higher short float suggests a greater portion of the stock is being bet against.
  • Days to Cover (Short Interest Ratio): This estimates how many days it would take short sellers to cover their positions, based on average daily trading volume. Higher values can signal potential for a short squeeze if buying pressure increases.

These metrics are often used by traders to gauge sentiment, volatility risk, and the potential for price movements based on short covering activity.


Related Companies
Short Interest Tools

Short interest data for NASDAQ:PYXS is sourced from the Financial Industry Regulatory Authority (FINRA), with the most recent report published on 8/25/2026. FINRA publishes updated short interest twice a month.
From Our Partners
How Long Does $2.5M Last in Retirement?
Having $2.5 million saved puts you ahead of most Americans, but how long it lasts depends on the decisions you...
SmartAsset | Sponsoredtc pixel
A Simple Guide to Options Trading While It's Still Free
A free copy of Options Trading Made Simple is available now but wont stay that way for long. Chris Rowe cal...
True Market Insiders | Sponsoredtc pixel
Before Anthropic becomes impossible to ignore...
Riot Platforms just struck a 20-year, 191-megawatt data-center agreement tied to Anthropic, reportedly worth 9...
The Oxford Club | Sponsoredtc pixel
Here’s the stock symbol I’ve promised
Whitney Tilson of Stansberry Research has long recommended Berkshire Hathaway as a core retirement holding - b...
Stansberry Research | Sponsoredtc pixel
Rickards Predicts: Trump to buy tiny $2 stock?
Jim Rickards believes the Trump administration is about to take a direct stake in a $2 stock sitting on the la...
Paradigm Press | Sponsoredtc pixel
Major Buy Alert Issued for September 30th
Keith Kaplan has invested $17 million into his own AI research tools, building a platform now used by 180,000 ...
TradeSmith | Sponsoredtc pixel
A weekly dividend fund holding Nvidia and Palantir
CrowdStrike, Palantir, Nvidia none of them pay a real dividend. But one fund holding the biggest AI names dist...
Investors Alley | Sponsoredtc pixel
Three companies about to leapfrog Nvidia [And transform the entire industry]
In 1984, a 10000 dollar stake in Apple could have grown to 25 million dollars for early investors who simply g...
Eagle Publishing | Sponsoredtc pixel