Pyxis Oncology (PYXS) Competitors

$1.91 -0.11 (-5.45%)

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$1.92 +0.01 (+0.26%)

As of 04:53 PM Eastern

PYXS vs. CTMX, CYRX, ZVRA, CLYM, and TLRY

Should you buy Pyxis Oncology stock or one of its competitors? MarketBeat compares Pyxis Oncology with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Pyxis Oncology include CytomX Therapeutics (CTMX), CryoPort (CYRX), Zevra Therapeutics (ZVRA), Climb Bio (CLYM), and Tilray Brands (TLRY). These companies are all part of the "pharmaceutical products" industry.

How does Pyxis Oncology compare to CytomX Therapeutics?

Pyxis Oncology (NASDAQ:PYXS) and CytomX Therapeutics (NASDAQ:CTMX) are both small-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, risk, earnings, dividends, analyst recommendations, institutional ownership, profitability and media sentiment.

Pyxis Oncology has a net margin of 0.00% compared to CytomX Therapeutics' net margin of -166.40%. CytomX Therapeutics' return on equity of -36.61% beat Pyxis Oncology's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Pyxis Oncology	N/A	-135.60%	-85.00%
CytomX Therapeutics	-166.40%	-36.61%	-28.02%

In the previous week, Pyxis Oncology had 10 more articles in the media than CytomX Therapeutics. MarketBeat recorded 21 mentions for Pyxis Oncology and 11 mentions for CytomX Therapeutics. CytomX Therapeutics' average media sentiment score of 0.93 beat Pyxis Oncology's score of 0.12 indicating that CytomX Therapeutics is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Pyxis Oncology	0 Very Positive mention(s)	1 Positive mention(s)	6 Neutral mention(s)	0 Negative mention(s)	1 Very Negative mention(s)	Neutral
CytomX Therapeutics	1 Very Positive mention(s)	0 Positive mention(s)	2 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Pyxis Oncology currently has a consensus target price of $6.83, suggesting a potential upside of 257.77%. CytomX Therapeutics has a consensus target price of $12.10, suggesting a potential upside of 232.42%. Given Pyxis Oncology's higher probable upside, research analysts clearly believe Pyxis Oncology is more favorable than CytomX Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Pyxis Oncology	1 Sell rating(s)	1 Hold rating(s)	6 Buy rating(s)	0 Strong Buy rating(s)	2.63
CytomX Therapeutics	1 Sell rating(s)	0 Hold rating(s)	10 Buy rating(s)	0 Strong Buy rating(s)	2.82

39.1% of Pyxis Oncology shares are held by institutional investors. Comparatively, 67.8% of CytomX Therapeutics shares are held by institutional investors. 10.6% of Pyxis Oncology shares are held by insiders. Comparatively, 6.6% of CytomX Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

CytomX Therapeutics has higher revenue and earnings than Pyxis Oncology. CytomX Therapeutics is trading at a lower price-to-earnings ratio than Pyxis Oncology, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Pyxis Oncology	$13.86M	8.66	-$79.62M	-$1.31	N/A
CytomX Therapeutics	$76.20M	8.13	-$17.37M	-$0.41	N/A

Pyxis Oncology has a beta of 1.43, indicating that its share price is 43% more volatile than the broader market. Comparatively, CytomX Therapeutics has a beta of 2.18, indicating that its share price is 118% more volatile than the broader market.

Summary

CytomX Therapeutics beats Pyxis Oncology on 10 of the 16 factors compared between the two stocks.

How does Pyxis Oncology compare to CryoPort?

CryoPort (NASDAQ:CYRX) and Pyxis Oncology (NASDAQ:PYXS) are both small-cap pharmaceutical products companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, earnings, profitability, risk, dividends, media sentiment, institutional ownership and valuation.

CryoPort presently has a consensus price target of $14.44, indicating a potential upside of 10.80%. Pyxis Oncology has a consensus price target of $6.83, indicating a potential upside of 257.77%. Given Pyxis Oncology's higher probable upside, analysts plainly believe Pyxis Oncology is more favorable than CryoPort.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
CryoPort	0 Sell rating(s)	1 Hold rating(s)	8 Buy rating(s)	0 Strong Buy rating(s)	2.89
Pyxis Oncology	1 Sell rating(s)	1 Hold rating(s)	6 Buy rating(s)	0 Strong Buy rating(s)	2.63

CryoPort has a net margin of 41.57% compared to Pyxis Oncology's net margin of 0.00%. CryoPort's return on equity of -7.92% beat Pyxis Oncology's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
CryoPort	41.57%	-7.92%	-4.79%
Pyxis Oncology	N/A	-135.60%	-85.00%

In the previous week, Pyxis Oncology had 20 more articles in the media than CryoPort. MarketBeat recorded 21 mentions for Pyxis Oncology and 1 mentions for CryoPort. CryoPort's average media sentiment score of 0.56 beat Pyxis Oncology's score of 0.12 indicating that CryoPort is being referred to more favorably in the media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
CryoPort	1 Very Positive mention(s)	0 Positive mention(s)	0 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive
Pyxis Oncology	0 Very Positive mention(s)	1 Positive mention(s)	6 Neutral mention(s)	0 Negative mention(s)	1 Very Negative mention(s)	Neutral

CryoPort has a beta of 1.75, meaning that its share price is 75% more volatile than the broader market. Comparatively, Pyxis Oncology has a beta of 1.43, meaning that its share price is 43% more volatile than the broader market.

CryoPort has higher revenue and earnings than Pyxis Oncology. Pyxis Oncology is trading at a lower price-to-earnings ratio than CryoPort, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
CryoPort	$176.18M	3.73	$78.30M	$1.35	9.65
Pyxis Oncology	$13.86M	8.66	-$79.62M	-$1.31	N/A

92.9% of CryoPort shares are owned by institutional investors. Comparatively, 39.1% of Pyxis Oncology shares are owned by institutional investors. 10.1% of CryoPort shares are owned by insiders. Comparatively, 10.6% of Pyxis Oncology shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

CryoPort beats Pyxis Oncology on 12 of the 16 factors compared between the two stocks.

How does Pyxis Oncology compare to Zevra Therapeutics?

Pyxis Oncology (NASDAQ:PYXS) and Zevra Therapeutics (NASDAQ:ZVRA) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, profitability, earnings, dividends, media sentiment, valuation, risk and analyst recommendations.

In the previous week, Pyxis Oncology had 20 more articles in the media than Zevra Therapeutics. MarketBeat recorded 21 mentions for Pyxis Oncology and 1 mentions for Zevra Therapeutics. Pyxis Oncology's average media sentiment score of 0.12 beat Zevra Therapeutics' score of -0.34 indicating that Pyxis Oncology is being referred to more favorably in the media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Pyxis Oncology	0 Very Positive mention(s)	1 Positive mention(s)	6 Neutral mention(s)	0 Negative mention(s)	1 Very Negative mention(s)	Neutral
Zevra Therapeutics	0 Very Positive mention(s)	0 Positive mention(s)	0 Neutral mention(s)	1 Negative mention(s)	0 Very Negative mention(s)	Neutral

Pyxis Oncology has a beta of 1.43, suggesting that its stock price is 43% more volatile than the broader market. Comparatively, Zevra Therapeutics has a beta of 0.88, suggesting that its stock price is 12% less volatile than the broader market.

Zevra Therapeutics has a net margin of 101.58% compared to Pyxis Oncology's net margin of 0.00%. Zevra Therapeutics' return on equity of 51.49% beat Pyxis Oncology's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Pyxis Oncology	N/A	-135.60%	-85.00%
Zevra Therapeutics	101.58%	51.49%	28.86%

Zevra Therapeutics has higher revenue and earnings than Pyxis Oncology. Pyxis Oncology is trading at a lower price-to-earnings ratio than Zevra Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Pyxis Oncology	$13.86M	8.66	-$79.62M	-$1.31	N/A
Zevra Therapeutics	$106.47M	5.66	$83.23M	$1.99	5.13

39.1% of Pyxis Oncology shares are owned by institutional investors. Comparatively, 35.0% of Zevra Therapeutics shares are owned by institutional investors. 10.6% of Pyxis Oncology shares are owned by company insiders. Comparatively, 2.4% of Zevra Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Pyxis Oncology presently has a consensus target price of $6.83, indicating a potential upside of 257.77%. Zevra Therapeutics has a consensus target price of $23.33, indicating a potential upside of 128.76%. Given Pyxis Oncology's higher possible upside, equities analysts plainly believe Pyxis Oncology is more favorable than Zevra Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Pyxis Oncology	1 Sell rating(s)	1 Hold rating(s)	6 Buy rating(s)	0 Strong Buy rating(s)	2.63
Zevra Therapeutics	0 Sell rating(s)	1 Hold rating(s)	8 Buy rating(s)	0 Strong Buy rating(s)	2.89

Summary

Zevra Therapeutics beats Pyxis Oncology on 9 of the 16 factors compared between the two stocks.

How does Pyxis Oncology compare to Climb Bio?

Pyxis Oncology (NASDAQ:PYXS) and Climb Bio (NASDAQ:CLYM) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their dividends, institutional ownership, risk, profitability, media sentiment, valuation, analyst recommendations and earnings.

39.1% of Pyxis Oncology shares are owned by institutional investors. Comparatively, 69.8% of Climb Bio shares are owned by institutional investors. 10.6% of Pyxis Oncology shares are owned by company insiders. Comparatively, 2.6% of Climb Bio shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Pyxis Oncology has a beta of 1.43, meaning that its share price is 43% more volatile than the broader market. Comparatively, Climb Bio has a beta of 0.02, meaning that its share price is 98% less volatile than the broader market.

In the previous week, Pyxis Oncology had 6 more articles in the media than Climb Bio. MarketBeat recorded 21 mentions for Pyxis Oncology and 15 mentions for Climb Bio. Climb Bio's average media sentiment score of 0.62 beat Pyxis Oncology's score of 0.12 indicating that Climb Bio is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Pyxis Oncology	0 Very Positive mention(s)	1 Positive mention(s)	6 Neutral mention(s)	0 Negative mention(s)	1 Very Negative mention(s)	Neutral
Climb Bio	0 Very Positive mention(s)	1 Positive mention(s)	5 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Pyxis Oncology presently has a consensus price target of $6.83, indicating a potential upside of 257.77%. Climb Bio has a consensus price target of $20.30, indicating a potential upside of 109.99%. Given Pyxis Oncology's higher possible upside, analysts plainly believe Pyxis Oncology is more favorable than Climb Bio.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Pyxis Oncology	1 Sell rating(s)	1 Hold rating(s)	6 Buy rating(s)	0 Strong Buy rating(s)	2.63
Climb Bio	1 Sell rating(s)	0 Hold rating(s)	9 Buy rating(s)	3 Strong Buy rating(s)	3.08

Climb Bio has lower revenue, but higher earnings than Pyxis Oncology. Climb Bio is trading at a lower price-to-earnings ratio than Pyxis Oncology, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Pyxis Oncology	$13.86M	8.66	-$79.62M	-$1.31	N/A
Climb Bio	N/A	N/A	-$59.85M	-$0.78	N/A

Climb Bio's return on equity of -31.45% beat Pyxis Oncology's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Pyxis Oncology	N/A	-135.60%	-85.00%
Climb Bio	N/A	-31.45%	-30.39%

Summary

Climb Bio beats Pyxis Oncology on 9 of the 15 factors compared between the two stocks.

How does Pyxis Oncology compare to Tilray Brands?

Tilray Brands (NASDAQ:TLRY) and Pyxis Oncology (NASDAQ:PYXS) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, media sentiment, dividends, earnings, risk, analyst recommendations, profitability and valuation.

Tilray Brands presently has a consensus target price of $11.50, indicating a potential upside of 120.73%. Pyxis Oncology has a consensus target price of $6.83, indicating a potential upside of 257.77%. Given Pyxis Oncology's stronger consensus rating and higher probable upside, analysts plainly believe Pyxis Oncology is more favorable than Tilray Brands.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Tilray Brands	1 Sell rating(s)	4 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.25
Pyxis Oncology	1 Sell rating(s)	1 Hold rating(s)	6 Buy rating(s)	0 Strong Buy rating(s)	2.63

Tilray Brands has a beta of 1.94, suggesting that its share price is 94% more volatile than the broader market. Comparatively, Pyxis Oncology has a beta of 1.43, suggesting that its share price is 43% more volatile than the broader market.

In the previous week, Pyxis Oncology had 15 more articles in the media than Tilray Brands. MarketBeat recorded 21 mentions for Pyxis Oncology and 6 mentions for Tilray Brands. Tilray Brands' average media sentiment score of 0.24 beat Pyxis Oncology's score of 0.12 indicating that Tilray Brands is being referred to more favorably in the media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Tilray Brands	1 Very Positive mention(s)	0 Positive mention(s)	5 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Neutral
Pyxis Oncology	0 Very Positive mention(s)	1 Positive mention(s)	6 Neutral mention(s)	0 Negative mention(s)	1 Very Negative mention(s)	Neutral

Pyxis Oncology has lower revenue, but higher earnings than Tilray Brands. Pyxis Oncology is trading at a lower price-to-earnings ratio than Tilray Brands, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Tilray Brands	$821.31M	0.74	-$2.19B	-$13.65	N/A
Pyxis Oncology	$13.86M	8.66	-$79.62M	-$1.31	N/A

Pyxis Oncology has a net margin of 0.00% compared to Tilray Brands' net margin of -156.51%. Tilray Brands' return on equity of -3.31% beat Pyxis Oncology's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Tilray Brands	-156.51%	-3.31%	-2.42%
Pyxis Oncology	N/A	-135.60%	-85.00%

9.4% of Tilray Brands shares are held by institutional investors. Comparatively, 39.1% of Pyxis Oncology shares are held by institutional investors. 0.8% of Tilray Brands shares are held by company insiders. Comparatively, 10.6% of Pyxis Oncology shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Summary

Pyxis Oncology beats Tilray Brands on 10 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PYXS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

PYXS vs. The Competition

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Metric	Pyxis Oncology	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$120.05M	$2.97B	$6.25B	$12.10B
Dividend Yield	N/A	1.98%	2.80%	5.32%
P/E Ratio	-1.46	17.29	20.60	25.11
Price / Sales	8.66	571.54	577.42	91.29
Price / Cash	N/A	56.35	27.48	37.30
Price / Book	2.22	3.91	9.68	6.60
Net Income	-$79.62M	$74.99M	$3.55B	$335.60M
7 Day Performance	-26.54%	-4.89%	-2.07%	-2.03%
1 Month Performance	15.06%	-8.30%	-3.90%	-1.90%
1 Year Performance	55.28%	28.66%	29.37%	27.35%

Pyxis Oncology Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
PYXS Pyxis Oncology	3.3106 of 5 stars	$1.91 -5.4%	$6.83 +257.8%	+66.9%	$120.05M	$13.86M	N/A	60	Trending News Earnings Report Upcoming Earnings Analyst Downgrade Analyst Revision
CTMX CytomX Therapeutics	3.2551 of 5 stars	$3.89 +0.9%	$12.78 +228.1%	+72.4%	$661.19M	$76.20M	N/A	170	Analyst Forecast Gap Down
CYRX CryoPort	3.5231 of 5 stars	$13.01 -1.3%	$14.44 +11.0%	+99.3%	$655.60M	$176.18M	9.64	1,186
ZVRA Zevra Therapeutics	3.7722 of 5 stars	$11.04 +2.2%	$23.33 +111.4%	+20.4%	$651.50M	$106.47M	5.54	20
CLYM Climb Bio	3.4767 of 5 stars	$11.17 +0.4%	$20.30 +81.8%	+665.9%	$642.46M	N/A	N/A	9

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This page (NASDAQ:PYXS) was last updated on 5/19/2026 by MarketBeat.com Staff.

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Pyxis Oncology (PYXS) Competitors

PYXS vs. CTMX, CYRX, ZVRA, CLYM, and TLRY

How does Pyxis Oncology compare to CytomX Therapeutics?

Summary

How does Pyxis Oncology compare to CryoPort?

Summary

How does Pyxis Oncology compare to Zevra Therapeutics?

Summary

How does Pyxis Oncology compare to Climb Bio?

Summary

How does Pyxis Oncology compare to Tilray Brands?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

PYXS vs. The Competition

Pyxis Oncology Competitors List

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Pyxis Oncology (PYXS) Competitors

PYXS vs. CTMX, CYRX, ZVRA, CLYM, and TLRY

How does Pyxis Oncology compare to CytomX Therapeutics?

Is PYXS or CTMX more profitable?

Does the media refer more to PYXS or CTMX?

Do analysts prefer PYXS or CTMX?

Do institutionals and insiders hold more shares of PYXS or CTMX?

Which has preferable earnings & valuation, PYXS or CTMX?

Which has more risk and volatility, PYXS or CTMX?

Summary

How does Pyxis Oncology compare to CryoPort?

Do analysts prefer CYRX or PYXS?

Is CYRX or PYXS more profitable?

Does the media favor CYRX or PYXS?

Which has more risk & volatility, CYRX or PYXS?

Which has preferable earnings & valuation, CYRX or PYXS?

Do institutionals & insiders have more ownership in CYRX or PYXS?

Summary

How does Pyxis Oncology compare to Zevra Therapeutics?

Does the media refer more to PYXS or ZVRA?

Which has more volatility & risk, PYXS or ZVRA?

Is PYXS or ZVRA more profitable?

Which has higher earnings & valuation, PYXS or ZVRA?

Do institutionals and insiders believe in PYXS or ZVRA?

Do analysts prefer PYXS or ZVRA?

Summary

How does Pyxis Oncology compare to Climb Bio?

Do insiders & institutionals believe in PYXS or CLYM?

Which has more volatility & risk, PYXS or CLYM?

Does the media prefer PYXS or CLYM?

Do analysts prefer PYXS or CLYM?

Which has higher valuation and earnings, PYXS or CLYM?

Is PYXS or CLYM more profitable?

Summary

How does Pyxis Oncology compare to Tilray Brands?

Do analysts rate TLRY or PYXS?

Which has more risk & volatility, TLRY or PYXS?

Does the media favor TLRY or PYXS?

Which has stronger earnings and valuation, TLRY or PYXS?

Is TLRY or PYXS more profitable?

Do institutionals and insiders have more ownership in TLRY or PYXS?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

PYXS vs. The Competition

Pyxis Oncology Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools