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Pyxis Oncology (PYXS) Competitors

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$2.03 +0.04 (+2.01%)
Closing price 10/9/2026 04:00 PM Eastern
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$2.03 0.00 (0.00%)
As of 10/9/2026 07:30 PM Eastern
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PYXS vs. GUTS, PHAR, IMMX, NVCT, and MDXG

Should you buy Pyxis Oncology stock or one of its competitors? Pyxis Oncology's main competitors and comparable companies include Fractyl Health (GUTS), Pharming Group (PHAR), Immix Biopharma (IMMX), Nuvectis Pharma (NVCT), and MiMedx Group (MDXG). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Pyxis Oncology compare to Fractyl Health?

Fractyl Health (NASDAQ:GUTS) and Pyxis Oncology (NASDAQ:PYXS) are both small-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their media sentiment, analyst recommendations, profitability, earnings, risk, institutional ownership, dividends and valuation.

In the previous week, Fractyl Health had 13 more articles in the media than Pyxis Oncology. MarketBeat recorded 18 mentions for Fractyl Health and 5 mentions for Pyxis Oncology. Pyxis Oncology's average media sentiment score of 0.82 beat Fractyl Health's score of -0.10 indicating that Pyxis Oncology is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
0 Very Positive mention(s)
0 Positive mention(s)
16 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Pyxis Oncology
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Fractyl Health has a beta of 2.42, suggesting that its share price is 142% more volatile than the broader market. Comparatively, Pyxis Oncology has a beta of 1.37, suggesting that its share price is 37% more volatile than the broader market.

Pyxis Oncology's return on equity of -215.23% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Pyxis Oncology N/A -215.23%-112.19%

Fractyl Health currently has a consensus price target of $66.00, indicating a potential upside of 1,393.21%. Pyxis Oncology has a consensus price target of $8.75, indicating a potential upside of 331.03%. Given Fractyl Health's higher possible upside, research analysts clearly believe Fractyl Health is more favorable than Pyxis Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70

Pyxis Oncology has higher revenue and earnings than Fractyl Health. Fractyl Health is trading at a lower price-to-earnings ratio than Pyxis Oncology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl Health$90K651.21-$140.95M-$0.88N/A
Pyxis Oncology$11.04M15.34-$79.62M-$1.41N/A

39.1% of Pyxis Oncology shares are held by institutional investors. 8.4% of Fractyl Health shares are held by insiders. Comparatively, 5.7% of Pyxis Oncology shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Summary

Fractyl Health beats Pyxis Oncology on 8 of the 15 factors compared between the two stocks.

How does Pyxis Oncology compare to Pharming Group?

Pyxis Oncology (NASDAQ:PYXS) and Pharming Group (NASDAQ:PHAR) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their dividends, earnings, risk, valuation, analyst recommendations, profitability, institutional ownership and media sentiment.

Pyxis Oncology presently has a consensus price target of $8.75, indicating a potential upside of 331.03%. Pharming Group has a consensus price target of $38.67, indicating a potential upside of 294.96%. Given Pyxis Oncology's stronger consensus rating and higher probable upside, equities research analysts plainly believe Pyxis Oncology is more favorable than Pharming Group.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70
Pharming Group
2 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.20

Pyxis Oncology has a beta of 1.37, indicating that its stock price is 37% more volatile than the broader market. Comparatively, Pharming Group has a beta of -0.05, indicating that its stock price is 105% less volatile than the broader market.

In the previous week, Pyxis Oncology had 3 more articles in the media than Pharming Group. MarketBeat recorded 5 mentions for Pyxis Oncology and 2 mentions for Pharming Group. Pyxis Oncology's average media sentiment score of 0.82 beat Pharming Group's score of 0.40 indicating that Pyxis Oncology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pyxis Oncology
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pharming Group
0 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Pharming Group has a net margin of 2.51% compared to Pyxis Oncology's net margin of 0.00%. Pharming Group's return on equity of 3.40% beat Pyxis Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
Pyxis OncologyN/A -215.23% -112.19%
Pharming Group 2.51%3.40%1.90%

39.1% of Pyxis Oncology shares are owned by institutional investors. Comparatively, 0.0% of Pharming Group shares are owned by institutional investors. 5.7% of Pyxis Oncology shares are owned by insiders. Comparatively, 2.1% of Pharming Group shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Pharming Group has higher revenue and earnings than Pyxis Oncology. Pyxis Oncology is trading at a lower price-to-earnings ratio than Pharming Group, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pyxis Oncology$11.04M15.34-$79.62M-$1.41N/A
Pharming Group$366.48M1.89$2.85M$0.1281.58

Summary

Pyxis Oncology beats Pharming Group on 9 of the 16 factors compared between the two stocks.

How does Pyxis Oncology compare to Immix Biopharma?

Pyxis Oncology (NASDAQ:PYXS) and Immix Biopharma (NASDAQ:IMMX) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, media sentiment, risk, dividends, profitability, analyst recommendations, institutional ownership and valuation.

39.1% of Pyxis Oncology shares are owned by institutional investors. Comparatively, 11.3% of Immix Biopharma shares are owned by institutional investors. 5.7% of Pyxis Oncology shares are owned by company insiders. Comparatively, 30.3% of Immix Biopharma shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Pyxis Oncology has a beta of 1.37, indicating that its share price is 37% more volatile than the broader market. Comparatively, Immix Biopharma has a beta of 0.24, indicating that its share price is 76% less volatile than the broader market.

In the previous week, Pyxis Oncology had 2 more articles in the media than Immix Biopharma. MarketBeat recorded 5 mentions for Pyxis Oncology and 3 mentions for Immix Biopharma. Pyxis Oncology's average media sentiment score of 0.82 beat Immix Biopharma's score of 0.41 indicating that Pyxis Oncology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pyxis Oncology
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Immix Biopharma
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Immix Biopharma's return on equity of -38.44% beat Pyxis Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
Pyxis OncologyN/A -215.23% -112.19%
Immix Biopharma N/A -38.44%-34.72%

Pyxis Oncology currently has a consensus target price of $8.75, indicating a potential upside of 331.03%. Immix Biopharma has a consensus target price of $24.14, indicating a potential upside of 155.21%. Given Pyxis Oncology's higher probable upside, research analysts clearly believe Pyxis Oncology is more favorable than Immix Biopharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70
Immix Biopharma
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.78

Immix Biopharma has lower revenue, but higher earnings than Pyxis Oncology. Immix Biopharma is trading at a lower price-to-earnings ratio than Pyxis Oncology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pyxis Oncology$11.04M15.34-$79.62M-$1.41N/A
Immix BiopharmaN/AN/A-$29.44M-$0.88N/A

Summary

Pyxis Oncology beats Immix Biopharma on 7 of the 13 factors compared between the two stocks.

How does Pyxis Oncology compare to Nuvectis Pharma?

Pyxis Oncology (NASDAQ:PYXS) and Nuvectis Pharma (NASDAQ:NVCT) are both small-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their valuation, profitability, risk, media sentiment, analyst recommendations, dividends, earnings and institutional ownership.

Pyxis Oncology has a beta of 1.37, suggesting that its stock price is 37% more volatile than the broader market. Comparatively, Nuvectis Pharma has a beta of -0.24, suggesting that its stock price is 124% less volatile than the broader market.

Nuvectis Pharma's return on equity of -184.25% beat Pyxis Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
Pyxis OncologyN/A -215.23% -112.19%
Nuvectis Pharma N/A -184.25%-105.24%

39.1% of Pyxis Oncology shares are held by institutional investors. Comparatively, 96.8% of Nuvectis Pharma shares are held by institutional investors. 5.7% of Pyxis Oncology shares are held by insiders. Comparatively, 28.5% of Nuvectis Pharma shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Nuvectis Pharma has lower revenue, but higher earnings than Pyxis Oncology. Nuvectis Pharma is trading at a lower price-to-earnings ratio than Pyxis Oncology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pyxis Oncology$11.04M15.34-$79.62M-$1.41N/A
Nuvectis PharmaN/AN/A-$26.44M-$1.31N/A

In the previous week, Pyxis Oncology had 1 more articles in the media than Nuvectis Pharma. MarketBeat recorded 5 mentions for Pyxis Oncology and 4 mentions for Nuvectis Pharma. Pyxis Oncology's average media sentiment score of 0.82 beat Nuvectis Pharma's score of 0.00 indicating that Pyxis Oncology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pyxis Oncology
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Nuvectis Pharma
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Pyxis Oncology presently has a consensus price target of $8.75, indicating a potential upside of 331.03%. Nuvectis Pharma has a consensus price target of $36.25, indicating a potential upside of 71.64%. Given Pyxis Oncology's higher possible upside, research analysts clearly believe Pyxis Oncology is more favorable than Nuvectis Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70
Nuvectis Pharma
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.80

Summary

Nuvectis Pharma beats Pyxis Oncology on 8 of the 15 factors compared between the two stocks.

How does Pyxis Oncology compare to MiMedx Group?

Pyxis Oncology (NASDAQ:PYXS) and MiMedx Group (NASDAQ:MDXG) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their profitability, media sentiment, risk, valuation, dividends, analyst recommendations, earnings and institutional ownership.

In the previous week, MiMedx Group had 1 more articles in the media than Pyxis Oncology. MarketBeat recorded 6 mentions for MiMedx Group and 5 mentions for Pyxis Oncology. Pyxis Oncology's average media sentiment score of 0.82 beat MiMedx Group's score of 0.20 indicating that Pyxis Oncology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pyxis Oncology
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
MiMedx Group
1 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Pyxis Oncology has a beta of 1.37, suggesting that its stock price is 37% more volatile than the broader market. Comparatively, MiMedx Group has a beta of 1.18, suggesting that its stock price is 18% more volatile than the broader market.

MiMedx Group has a net margin of 1.76% compared to Pyxis Oncology's net margin of 0.00%. MiMedx Group's return on equity of 12.09% beat Pyxis Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
Pyxis OncologyN/A -215.23% -112.19%
MiMedx Group 1.76%12.09%9.22%

Pyxis Oncology currently has a consensus target price of $8.75, indicating a potential upside of 331.03%. MiMedx Group has a consensus target price of $8.57, indicating a potential upside of 83.54%. Given Pyxis Oncology's higher probable upside, analysts plainly believe Pyxis Oncology is more favorable than MiMedx Group.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70
MiMedx Group
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

39.1% of Pyxis Oncology shares are held by institutional investors. Comparatively, 79.2% of MiMedx Group shares are held by institutional investors. 5.7% of Pyxis Oncology shares are held by insiders. Comparatively, 2.5% of MiMedx Group shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

MiMedx Group has higher revenue and earnings than Pyxis Oncology. Pyxis Oncology is trading at a lower price-to-earnings ratio than MiMedx Group, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pyxis Oncology$11.04M15.34-$79.62M-$1.41N/A
MiMedx Group$418.63M1.63$48.58M$0.04116.75

Summary

MiMedx Group beats Pyxis Oncology on 10 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PYXS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PYXS vs. The Competition

MetricPyxis OncologyBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$169.32M$3.85B$7.16B$13.21B
Dividend YieldN/A3.66%2.53%16.37%
P/E RatioN/A13.62275.3026.16
Price / Sales12.221,234.34635.99108.09
Price / CashN/A116.5676.3853.09
Price / Book2.3617.1711.226.33
Net Income-$79.62M-$22.69M$3.50B$382.15M
7 Day Performance-5.14%-1.34%-0.89%-1.40%
1 Month Performance-37.92%-8.45%-4.42%-3.47%
1 Year Performance-45.06%14.02%7.03%1.18%

Pyxis Oncology Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PYXS
Pyxis Oncology
2.6105 of 5 stars
$2.03
+2.0%
$8.75
+331.0%
-47.0%$169.32M$13.86MN/A56
GUTS
Fractyl Health
2.7401 of 5 stars
$4.43
-2.9%
$66.00
+1,389.8%
-73.7%$705.65M$90KN/A73
PHAR
Pharming Group
4.1869 of 5 stars
$9.88
+0.8%
$38.67
+291.4%
-32.9%$699.31M$376.13M82.33407
IMMX
Immix Biopharma
2.8127 of 5 stars
$9.71
-4.1%
$24.14
+148.6%
+266.7%$695.44MN/AN/A21
NVCT
Nuvectis Pharma
2.293 of 5 stars
$20.60
-3.7%
$36.25
+76.0%
+251.4%$672.22MN/AN/A13

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This page (NASDAQ:PYXS) was last updated on 10/10/2026 by MarketBeat.com Staff.
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