Annexon (ANNX) Competitors

$5.37 -0.08 (-1.47%)

Closing price 04:00 PM Eastern

Extended Trading

$5.44 +0.07 (+1.23%)

As of 06:36 PM Eastern

ANNX vs. OGN, TNGX, ERAS, BEAM, and ORKA

Should you buy Annexon stock or one of its competitors? MarketBeat compares Annexon with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Annexon include Organon & Co. (OGN), Tango Therapeutics (TNGX), Erasca (ERAS), Beam Therapeutics (BEAM), and Oruka Therapeutics (ORKA). These companies are all part of the "pharmaceutical products" industry.

How does Annexon compare to Organon & Co.?

Organon & Co. (NYSE:OGN) and Annexon (NASDAQ:ANNX) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their profitability, risk, earnings, dividends, valuation, analyst recommendations, institutional ownership and media sentiment.

Organon & Co. has higher revenue and earnings than Annexon. Annexon is trading at a lower price-to-earnings ratio than Organon & Co., indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Organon & Co.	$6.22B	0.56	$187M	$0.93	14.37
Annexon	N/A	N/A	-$206.69M	-$1.22	N/A

77.4% of Organon & Co. shares are held by institutional investors. 1.6% of Organon & Co. shares are held by company insiders. Comparatively, 11.9% of Annexon shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Organon & Co. has a net margin of 3.99% compared to Annexon's net margin of 0.00%. Organon & Co.'s return on equity of 99.95% beat Annexon's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Organon & Co.	3.99%	99.95%	6.22%
Annexon	N/A	-101.19%	-75.99%

In the previous week, Annexon had 17 more articles in the media than Organon & Co.. MarketBeat recorded 22 mentions for Annexon and 5 mentions for Organon & Co.. Organon & Co.'s average media sentiment score of 1.59 beat Annexon's score of 0.95 indicating that Organon & Co. is being referred to more favorably in the media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Organon & Co.	4 Very Positive mention(s)	1 Positive mention(s)	0 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Very Positive
Annexon	4 Very Positive mention(s)	3 Positive mention(s)	4 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Organon & Co. presently has a consensus target price of $11.40, indicating a potential downside of 14.70%. Annexon has a consensus target price of $16.00, indicating a potential upside of 197.95%. Given Annexon's stronger consensus rating and higher possible upside, analysts clearly believe Annexon is more favorable than Organon & Co..

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Organon & Co.	3 Sell rating(s)	4 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.57
Annexon	1 Sell rating(s)	2 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.43

Organon & Co. has a beta of 1.57, meaning that its stock price is 57% more volatile than the broader market. Comparatively, Annexon has a beta of 1.22, meaning that its stock price is 22% more volatile than the broader market.

Summary

Organon & Co. beats Annexon on 10 of the 15 factors compared between the two stocks.

How does Annexon compare to Tango Therapeutics?

Tango Therapeutics (NASDAQ:TNGX) and Annexon (NASDAQ:ANNX) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their profitability, risk, earnings, dividends, valuation, analyst recommendations, institutional ownership and media sentiment.

Tango Therapeutics presently has a consensus target price of $30.45, indicating a potential upside of 22.45%. Annexon has a consensus target price of $16.00, indicating a potential upside of 197.95%. Given Annexon's higher possible upside, analysts clearly believe Annexon is more favorable than Tango Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Tango Therapeutics	1 Sell rating(s)	2 Hold rating(s)	11 Buy rating(s)	0 Strong Buy rating(s)	2.71
Annexon	1 Sell rating(s)	2 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.43

79.0% of Tango Therapeutics shares are held by institutional investors. 6.5% of Tango Therapeutics shares are held by company insiders. Comparatively, 11.9% of Annexon shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

In the previous week, Annexon had 14 more articles in the media than Tango Therapeutics. MarketBeat recorded 22 mentions for Annexon and 8 mentions for Tango Therapeutics. Annexon's average media sentiment score of 0.95 beat Tango Therapeutics' score of 0.86 indicating that Annexon is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Tango Therapeutics	1 Very Positive mention(s)	0 Positive mention(s)	3 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive
Annexon	4 Very Positive mention(s)	3 Positive mention(s)	4 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Tango Therapeutics has a beta of 1.22, meaning that its stock price is 22% more volatile than the broader market. Comparatively, Annexon has a beta of 1.22, meaning that its stock price is 22% more volatile than the broader market.

Tango Therapeutics has higher revenue and earnings than Annexon. Tango Therapeutics is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Tango Therapeutics	$62.38M	57.51	-$101.59M	-$0.87	N/A
Annexon	N/A	N/A	-$206.69M	-$1.22	N/A

Annexon has a net margin of 0.00% compared to Tango Therapeutics' net margin of -151.15%. Tango Therapeutics' return on equity of -50.30% beat Annexon's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Tango Therapeutics	-151.15%	-50.30%	-36.25%
Annexon	N/A	-101.19%	-75.99%

Summary

Tango Therapeutics beats Annexon on 8 of the 14 factors compared between the two stocks.

How does Annexon compare to Erasca?

Erasca (NASDAQ:ERAS) and Annexon (NASDAQ:ANNX) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, profitability, valuation, institutional ownership, risk, dividends, earnings and analyst recommendations.

Erasca currently has a consensus price target of $18.75, indicating a potential upside of 80.81%. Annexon has a consensus price target of $16.00, indicating a potential upside of 197.95%. Given Annexon's higher possible upside, analysts plainly believe Annexon is more favorable than Erasca.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Erasca	2 Sell rating(s)	1 Hold rating(s)	7 Buy rating(s)	0 Strong Buy rating(s)	2.50
Annexon	1 Sell rating(s)	2 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.43

67.8% of Erasca shares are held by institutional investors. 14.2% of Erasca shares are held by company insiders. Comparatively, 11.9% of Annexon shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Erasca had 2 more articles in the media than Annexon. MarketBeat recorded 24 mentions for Erasca and 22 mentions for Annexon. Annexon's average media sentiment score of 0.95 beat Erasca's score of 0.10 indicating that Annexon is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Erasca	2 Very Positive mention(s)	2 Positive mention(s)	10 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Neutral
Annexon	4 Very Positive mention(s)	3 Positive mention(s)	4 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Erasca has a beta of 0.68, meaning that its share price is 32% less volatile than the broader market. Comparatively, Annexon has a beta of 1.22, meaning that its share price is 22% more volatile than the broader market.

Erasca is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Erasca	N/A	N/A	-$124.55M	-$0.93	N/A
Annexon	N/A	N/A	-$206.69M	-$1.22	N/A

Erasca's return on equity of -35.31% beat Annexon's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Erasca	N/A	-35.31%	-29.49%
Annexon	N/A	-101.19%	-75.99%

Summary

Erasca beats Annexon on 9 of the 13 factors compared between the two stocks.

How does Annexon compare to Beam Therapeutics?

Beam Therapeutics (NASDAQ:BEAM) and Annexon (NASDAQ:ANNX) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, profitability, risk, institutional ownership, earnings, analyst recommendations, valuation and dividends.

Beam Therapeutics has higher revenue and earnings than Annexon. Beam Therapeutics is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Beam Therapeutics	$164.01M	18.52	-$79.99M	-$0.68	N/A
Annexon	N/A	N/A	-$206.69M	-$1.22	N/A

99.7% of Beam Therapeutics shares are held by institutional investors. 3.8% of Beam Therapeutics shares are held by company insiders. Comparatively, 11.9% of Annexon shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Annexon has a net margin of 0.00% compared to Beam Therapeutics' net margin of -39.66%. Beam Therapeutics' return on equity of -29.00% beat Annexon's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Beam Therapeutics	-39.66%	-29.00%	-22.61%
Annexon	N/A	-101.19%	-75.99%

Beam Therapeutics currently has a consensus price target of $46.83, indicating a potential upside of 58.60%. Annexon has a consensus price target of $16.00, indicating a potential upside of 197.95%. Given Annexon's higher possible upside, analysts plainly believe Annexon is more favorable than Beam Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Beam Therapeutics	1 Sell rating(s)	3 Hold rating(s)	9 Buy rating(s)	1 Strong Buy rating(s)	2.71
Annexon	1 Sell rating(s)	2 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.43

Beam Therapeutics has a beta of 2.26, meaning that its stock price is 126% more volatile than the broader market. Comparatively, Annexon has a beta of 1.22, meaning that its stock price is 22% more volatile than the broader market.

In the previous week, Annexon had 10 more articles in the media than Beam Therapeutics. MarketBeat recorded 22 mentions for Annexon and 12 mentions for Beam Therapeutics. Annexon's average media sentiment score of 0.95 beat Beam Therapeutics' score of 0.72 indicating that Annexon is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Beam Therapeutics	4 Very Positive mention(s)	0 Positive mention(s)	6 Neutral mention(s)	0 Negative mention(s)	1 Very Negative mention(s)	Positive
Annexon	4 Very Positive mention(s)	3 Positive mention(s)	4 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Summary

Beam Therapeutics beats Annexon on 10 of the 16 factors compared between the two stocks.

How does Annexon compare to Oruka Therapeutics?

Annexon (NASDAQ:ANNX) and Oruka Therapeutics (NASDAQ:ORKA) are both medical companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, institutional ownership, media sentiment, risk, valuation, dividends, profitability and analyst recommendations.

56.4% of Oruka Therapeutics shares are owned by institutional investors. 11.9% of Annexon shares are owned by insiders. Comparatively, 23.5% of Oruka Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Annexon presently has a consensus price target of $16.00, indicating a potential upside of 197.95%. Oruka Therapeutics has a consensus price target of $120.80, indicating a potential upside of 89.05%. Given Annexon's higher probable upside, equities analysts plainly believe Annexon is more favorable than Oruka Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Annexon	1 Sell rating(s)	2 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.43
Oruka Therapeutics	1 Sell rating(s)	0 Hold rating(s)	10 Buy rating(s)	0 Strong Buy rating(s)	2.82

Oruka Therapeutics is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Annexon	N/A	N/A	-$206.69M	-$1.22	N/A
Oruka Therapeutics	N/A	N/A	-$105.43M	-$1.86	N/A

In the previous week, Annexon had 11 more articles in the media than Oruka Therapeutics. MarketBeat recorded 22 mentions for Annexon and 11 mentions for Oruka Therapeutics. Oruka Therapeutics' average media sentiment score of 1.16 beat Annexon's score of 0.95 indicating that Oruka Therapeutics is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Annexon	4 Very Positive mention(s)	3 Positive mention(s)	4 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive
Oruka Therapeutics	3 Very Positive mention(s)	1 Positive mention(s)	4 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Oruka Therapeutics' return on equity of -25.48% beat Annexon's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Annexon	N/A	-101.19%	-75.99%
Oruka Therapeutics	N/A	-25.48%	-24.34%

Annexon has a beta of 1.22, meaning that its stock price is 22% more volatile than the broader market. Comparatively, Oruka Therapeutics has a beta of -0.2, meaning that its stock price is 120% less volatile than the broader market.

Summary

Oruka Therapeutics beats Annexon on 8 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ANNX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

ANNX vs. The Competition

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Metric	Annexon	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$879.84M	$3.40B	$6.29B	$12.46B
Dividend Yield	N/A	2.31%	2.79%	5.30%
P/E Ratio	-4.40	18.98	20.89	25.59
Price / Sales	N/A	180.83	523.74	63.24
Price / Cash	N/A	122.51	42.94	55.34
Price / Book	4.30	6.74	9.86	6.70
Net Income	-$206.69M	$24.11M	$3.55B	$333.77M
7 Day Performance	-2.72%	0.08%	-0.33%	0.45%
1 Month Performance	-7.41%	0.84%	1.34%	4.06%
1 Year Performance	205.11%	78.10%	41.10%	36.24%

Annexon Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
ANNX Annexon	2.2504 of 5 stars	$5.37 -1.5%	$16.00 +198.0%	+211.4%	$879.84M	N/A	N/A	60	News Coverage Earnings Report Analyst Forecast Analyst Revision
OGN Organon & Co.	3.1511 of 5 stars	$13.35 -0.5%	$11.40 -14.6%	+58.1%	$3.50B	$6.22B	14.35	10,000	Positive News Ex-Dividend
TNGX Tango Therapeutics	2.7639 of 5 stars	$23.48 -0.6%	$22.44 -4.4%	+1,722.1%	$3.39B	$62.38M	N/A	90	Earnings Report Analyst Upgrade Gap Down High Trading Volume
ERAS Erasca	3.6832 of 5 stars	$10.40 -4.6%	$17.88 +71.9%	+686.5%	$3.23B	N/A	N/A	120	Trending News Earnings Report Analyst Forecast Analyst Revision
BEAM Beam Therapeutics	3.9838 of 5 stars	$31.47 -2.7%	$47.17 +49.9%	+76.5%	$3.23B	$139.74M	N/A	510	News Coverage Earnings Report Analyst Forecast

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This page (NASDAQ:ANNX) was last updated on 5/14/2026 by MarketBeat.com Staff.

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Annexon (ANNX) Competitors

ANNX vs. OGN, TNGX, ERAS, BEAM, and ORKA

How does Annexon compare to Organon & Co.?

Summary

How does Annexon compare to Tango Therapeutics?

Summary

How does Annexon compare to Erasca?

Summary

How does Annexon compare to Beam Therapeutics?

Summary

How does Annexon compare to Oruka Therapeutics?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

ANNX vs. The Competition

Annexon Competitors List

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Stock Ideas and Recommendations

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Annexon (ANNX) Competitors

ANNX vs. OGN, TNGX, ERAS, BEAM, and ORKA

How does Annexon compare to Organon & Co.?

Which has stronger valuation and earnings, OGN or ANNX?

Do insiders & institutionals hold more shares of OGN or ANNX?

Is OGN or ANNX more profitable?

Does the media favor OGN or ANNX?

Do analysts prefer OGN or ANNX?

Which has more risk and volatility, OGN or ANNX?

Summary

How does Annexon compare to Tango Therapeutics?

Do analysts prefer TNGX or ANNX?

Do insiders & institutionals hold more shares of TNGX or ANNX?

Does the media favor TNGX or ANNX?

Which has more risk and volatility, TNGX or ANNX?

Which has stronger valuation and earnings, TNGX or ANNX?

Is TNGX or ANNX more profitable?

Summary

How does Annexon compare to Erasca?

Do analysts prefer ERAS or ANNX?

Do institutionals and insiders believe in ERAS or ANNX?

Does the media prefer ERAS or ANNX?

Which has more risk & volatility, ERAS or ANNX?

Which has stronger earnings & valuation, ERAS or ANNX?

Is ERAS or ANNX more profitable?

Summary

How does Annexon compare to Beam Therapeutics?

Which has higher earnings and valuation, BEAM or ANNX?

Do insiders & institutionals believe in BEAM or ANNX?

Is BEAM or ANNX more profitable?

Do analysts prefer BEAM or ANNX?

Which has more volatility and risk, BEAM or ANNX?

Does the media prefer BEAM or ANNX?

Summary

How does Annexon compare to Oruka Therapeutics?

Do institutionals & insiders believe in ANNX or ORKA?

Do analysts recommend ANNX or ORKA?

Which has better valuation and earnings, ANNX or ORKA?

Does the media favor ANNX or ORKA?

Is ANNX or ORKA more profitable?

Which has more volatility and risk, ANNX or ORKA?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

ANNX vs. The Competition

Annexon Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools