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Annexon (ANNX) Competitors

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$3.94 -0.20 (-4.83%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$4.00 +0.06 (+1.50%)
As of 09/11/2026 07:39 PM Eastern
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ANNX vs. DNLI, VCYT, GRAL, IDYA, and ABCL

Should you buy Annexon stock or one of its competitors? Annexon's main competitors and comparable companies include Denali Therapeutics (DNLI), Veracyte (VCYT), GRAIL (GRAL), IDEAYA Biosciences (IDYA), and AbCellera Biologics (ABCL). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Annexon compare to Denali Therapeutics?

Denali Therapeutics (NASDAQ:DNLI) and Annexon (NASDAQ:ANNX) are both healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their risk, analyst recommendations, dividends, media sentiment, institutional ownership, profitability, valuation and earnings.

Annexon has lower revenue, but higher earnings than Denali Therapeutics. Denali Therapeutics is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$330.53M10.20-$512.54M-$2.84N/A
AnnexonN/AN/A-$206.69M-$1.16N/A

Denali Therapeutics has a beta of 1.01, meaning that its stock price is 1% more volatile than the broader market. Comparatively, Annexon has a beta of 1.21, meaning that its stock price is 21% more volatile than the broader market.

In the previous week, Annexon had 3 more articles in the media than Denali Therapeutics. MarketBeat recorded 5 mentions for Annexon and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.46 beat Annexon's score of 0.89 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Annexon
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Denali Therapeutics currently has a consensus target price of $35.85, suggesting a potential upside of 69.97%. Annexon has a consensus target price of $15.14, suggesting a potential upside of 284.34%. Given Annexon's higher possible upside, analysts plainly believe Annexon is more favorable than Denali Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75
Annexon
2 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.40

Denali Therapeutics' return on equity of -55.27% beat Annexon's return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -55.27% -44.24%
Annexon N/A -106.15%-79.82%

92.9% of Denali Therapeutics shares are held by institutional investors. 9.7% of Denali Therapeutics shares are held by company insiders. Comparatively, 10.3% of Annexon shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Summary

Denali Therapeutics and Annexon tied by winning 7 of the 14 factors compared between the two stocks.

How does Annexon compare to Veracyte?

Annexon (NASDAQ:ANNX) and Veracyte (NASDAQ:VCYT) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their analyst recommendations, profitability, risk, media sentiment, valuation, earnings, institutional ownership and dividends.

Annexon currently has a consensus target price of $15.14, indicating a potential upside of 284.34%. Veracyte has a consensus target price of $55.78, indicating a potential upside of 36.48%. Given Annexon's higher possible upside, analysts plainly believe Annexon is more favorable than Veracyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Annexon
2 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.40
Veracyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
3 Strong Buy rating(s)
2.91

Annexon has a beta of 1.21, suggesting that its share price is 21% more volatile than the broader market. Comparatively, Veracyte has a beta of 1.93, suggesting that its share price is 93% more volatile than the broader market.

In the previous week, Veracyte had 1 more articles in the media than Annexon. MarketBeat recorded 6 mentions for Veracyte and 5 mentions for Annexon. Annexon's average media sentiment score of 0.89 beat Veracyte's score of 0.44 indicating that Annexon is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Annexon
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Veracyte
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Veracyte has higher revenue and earnings than Annexon. Annexon is trading at a lower price-to-earnings ratio than Veracyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AnnexonN/AN/A-$206.69M-$1.16N/A
Veracyte$517.15M6.35$66.35M$1.4128.99

Veracyte has a net margin of 20.37% compared to Annexon's net margin of 0.00%. Veracyte's return on equity of 9.26% beat Annexon's return on equity.

Company Net Margins Return on Equity Return on Assets
AnnexonN/A -106.15% -79.82%
Veracyte 20.37%9.26%8.61%

Summary

Veracyte beats Annexon on 11 of the 14 factors compared between the two stocks.

How does Annexon compare to GRAIL?

GRAIL (NASDAQ:GRAL) and Annexon (NASDAQ:ANNX) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their media sentiment, valuation, institutional ownership, earnings, profitability, risk, analyst recommendations and dividends.

GRAIL has a beta of 3.25, indicating that its stock price is 225% more volatile than the broader market. Comparatively, Annexon has a beta of 1.21, indicating that its stock price is 21% more volatile than the broader market.

GRAIL presently has a consensus price target of $71.11, indicating a potential downside of 6.72%. Annexon has a consensus price target of $15.14, indicating a potential upside of 284.34%. Given Annexon's higher possible upside, analysts clearly believe Annexon is more favorable than GRAIL.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
GRAIL
1 Sell rating(s)
5 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.45
Annexon
2 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.40

In the previous week, GRAIL had 4 more articles in the media than Annexon. MarketBeat recorded 9 mentions for GRAIL and 5 mentions for Annexon. GRAIL's average media sentiment score of 0.96 beat Annexon's score of 0.89 indicating that GRAIL is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
GRAIL
3 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Annexon
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Annexon has a net margin of 0.00% compared to GRAIL's net margin of -236.95%. GRAIL's return on equity of -15.88% beat Annexon's return on equity.

Company Net Margins Return on Equity Return on Assets
GRAIL-236.95% -15.88% -14.02%
Annexon N/A -106.15%-79.82%

Annexon has lower revenue, but higher earnings than GRAIL. GRAIL is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
GRAIL$165.26M20.60-$408.35M-$9.75N/A
AnnexonN/AN/A-$206.69M-$1.16N/A

Summary

GRAIL beats Annexon on 8 of the 14 factors compared between the two stocks.

How does Annexon compare to IDEAYA Biosciences?

Annexon (NASDAQ:ANNX) and IDEAYA Biosciences (NASDAQ:IDYA) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their institutional ownership, media sentiment, risk, valuation, analyst recommendations, dividends, earnings and profitability.

Annexon currently has a consensus price target of $15.14, indicating a potential upside of 284.34%. IDEAYA Biosciences has a consensus price target of $52.69, indicating a potential upside of 40.18%. Given Annexon's higher probable upside, equities research analysts clearly believe Annexon is more favorable than IDEAYA Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Annexon
2 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.40
IDEAYA Biosciences
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.80

IDEAYA Biosciences has higher revenue and earnings than Annexon. IDEAYA Biosciences is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AnnexonN/AN/A-$206.69M-$1.16N/A
IDEAYA Biosciences$218.71M15.10-$113.70M-$1.94N/A

In the previous week, IDEAYA Biosciences had 8 more articles in the media than Annexon. MarketBeat recorded 13 mentions for IDEAYA Biosciences and 5 mentions for Annexon. Annexon's average media sentiment score of 0.89 beat IDEAYA Biosciences' score of 0.64 indicating that Annexon is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Annexon
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
IDEAYA Biosciences
3 Very Positive mention(s)
0 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Annexon has a beta of 1.21, indicating that its share price is 21% more volatile than the broader market. Comparatively, IDEAYA Biosciences has a beta of -0.07, indicating that its share price is 107% less volatile than the broader market.

98.3% of IDEAYA Biosciences shares are held by institutional investors. 10.3% of Annexon shares are held by company insiders. Comparatively, 4.7% of IDEAYA Biosciences shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Annexon has a net margin of 0.00% compared to IDEAYA Biosciences' net margin of -75.93%. IDEAYA Biosciences' return on equity of -16.73% beat Annexon's return on equity.

Company Net Margins Return on Equity Return on Assets
AnnexonN/A -106.15% -79.82%
IDEAYA Biosciences -75.93%-16.73%-15.34%

Summary

IDEAYA Biosciences beats Annexon on 8 of the 15 factors compared between the two stocks.

How does Annexon compare to AbCellera Biologics?

Annexon (NASDAQ:ANNX) and AbCellera Biologics (NASDAQ:ABCL) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their profitability, earnings, valuation, media sentiment, analyst recommendations, risk, institutional ownership and dividends.

In the previous week, Annexon had 3 more articles in the media than AbCellera Biologics. MarketBeat recorded 5 mentions for Annexon and 2 mentions for AbCellera Biologics. AbCellera Biologics' average media sentiment score of 1.02 beat Annexon's score of 0.89 indicating that AbCellera Biologics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Annexon
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
AbCellera Biologics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Annexon has a beta of 1.21, suggesting that its share price is 21% more volatile than the broader market. Comparatively, AbCellera Biologics has a beta of 1.32, suggesting that its share price is 32% more volatile than the broader market.

61.4% of AbCellera Biologics shares are owned by institutional investors. 10.3% of Annexon shares are owned by company insiders. Comparatively, 28.4% of AbCellera Biologics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

AbCellera Biologics has higher revenue and earnings than Annexon. AbCellera Biologics is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AnnexonN/AN/A-$206.69M-$1.16N/A
AbCellera Biologics$66.17M50.46-$146.41M-$0.54N/A

Annexon has a net margin of 0.00% compared to AbCellera Biologics' net margin of -248.83%. AbCellera Biologics' return on equity of -17.49% beat Annexon's return on equity.

Company Net Margins Return on Equity Return on Assets
AnnexonN/A -106.15% -79.82%
AbCellera Biologics -248.83%-17.49%-12.36%

Annexon presently has a consensus price target of $15.14, suggesting a potential upside of 284.34%. AbCellera Biologics has a consensus price target of $12.83, suggesting a potential upside of 17.85%. Given Annexon's higher probable upside, equities analysts plainly believe Annexon is more favorable than AbCellera Biologics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Annexon
2 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.40
AbCellera Biologics
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71

Summary

AbCellera Biologics beats Annexon on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ANNX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ANNX vs. The Competition

MetricAnnexonBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$784.86M$3.84B$7.13B$12.72B
Dividend YieldN/A3.63%2.56%11.15%
P/E Ratio-3.4014.25275.2425.29
Price / SalesN/A1,473.06655.9998.94
Price / CashN/A106.6877.0451.44
Price / Book2.7715.1210.336.20
Net Income-$206.69M-$22.86M$3.50B$358.50M
7 Day Performance-19.10%-4.34%-3.32%-2.35%
1 Month Performance-26.08%-0.02%-0.41%-2.77%
1 Year Performance62.81%40.64%19.21%7.63%

Annexon Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ANNX
Annexon
2.4103 of 5 stars
$3.94
-4.8%
$15.14
+284.3%
+54.5%$784.86MN/AN/A60
DNLI
Denali Therapeutics
3.7567 of 5 stars
$22.80
-0.2%
$35.85
+57.2%
+42.3%$3.65B$330.53MN/A430
VCYT
Veracyte
4.3682 of 5 stars
$44.67
-0.5%
$54.33
+21.6%
+28.3%$3.61B$517.15M31.68790
GRAL
GRAIL
0.6883 of 5 stars
$80.62
+0.1%
$67.78
-15.9%
+97.2%$3.60B$147.17MN/A1,360
IDYA
IDEAYA Biosciences
3.1081 of 5 stars
$39.97
-0.5%
$50.19
+25.6%
+50.8%$3.53B$218.71MN/A80

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This page (NASDAQ:ANNX) was last updated on 9/12/2026 by MarketBeat.com Staff.
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