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Annexon (ANNX) Institutional Ownership

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$4.19 +0.07 (+1.70%)
Closing price 10/2/2026 04:00 PM Eastern
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$4.26 +0.07 (+1.67%)
As of 10/2/2026 07:31 PM Eastern
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Institutional Ownership Changes (13F Filings) for Annexon (NASDAQ:ANNX)

Number of
Institutional Buyers
(last 12 months)
108
Total
Institutional Inflows
(last 12 months)
$316.89M
Number of
Institutional Sellers
(last 12 months)
31
Total
Institutional Outflows
(last 12 months)
$22.37M
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ANNX Institutional Buying and Selling by Quarter

Annexon Major Shareholders & Ownership History

Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
9/9/2026Opaleye Management Inc.1,714,451$9.79M0.9%-26.5%0.904%
9/9/2026WINTON GROUP Ltd47,800$273K0.0%+98.3%0.025%
9/9/2026Engineers Gate Manager LP319,057$1.82M0.0%+83.2%0.168%
9/9/2026Integrated Wealth Concepts LLC13,537$77K0.0%+32.3%0.007%
9/9/2026Squarepoint Ops LLC173,285$989K0.0%+155.0%0.091%
8/25/2026VIRGINIA RETIREMENT SYSTEMS ET Al54,300$310K0.0%N/A0.029%
8/20/2026Susquehanna Fundamental Investments LLC21,010$120K0.0%N/A0.011%
8/20/2026Moore Capital Management LP425,332$2.43M0.0%N/A0.224%
8/19/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC180,647$1.03M0.0%+38.3%0.095%
8/19/2026Wellington Management Group LLP406,795$2.32M0.0%-22.0%0.215%
8/18/2026Palo Alto Investors LP2,948,090$16.83M0.0%N/A1.555%
8/18/2026Coastal Bridge Advisors LLC17,000$97K0.0%N/A0.009%
8/17/2026Corient Private Wealth LP19,704$113K0.0%N/A0.010%
8/17/2026Bank of America Corp DE614,186$3.51M0.0%N/A0.324%
8/15/2026Jupiter Topco LLC59,100$338K0.0%N/A0.031%
8/15/2026J. Goldman & Co LP116,046$663K0.0%N/A0.061%
8/14/2026Canada Pension Plan Investment Board38,600$220K0.0%N/A0.024%
8/14/2026Parkman Healthcare Partners LLC641,029$3.66M0.4%N/A0.391%
8/14/2026Legal & General Group Plc98,118$560K0.0%N/A0.060%
8/14/2026The Manufacturers Life Insurance Company41,517$237K0.0%N/A0.025%
8/13/2026Forefront Analytics LLC14,240$81K0.1%N/A0.009%
8/12/2026Landscape Capital Management L.L.C.20,813$119K0.0%N/A0.013%
8/12/2026Ieq Capital LLC120,010$685K0.0%N/A0.073%
8/11/2026E Fund Management Co. Ltd.24,433$140K0.0%N/A0.015%
8/7/2026BlackRock Inc.13,539,744$77.31M0.0%N/A8.264%
8/7/2026Deutsche Bank AG616,489$3.52M0.0%N/A0.376%
8/6/2026SCS Capital Management LLC99,000$565K0.0%N/A0.060%
8/6/2026Bank of New York Mellon Corp501,442$2.86M0.0%N/A0.306%
8/6/2026State of Wyoming19,479$111K0.0%N/A0.012%
8/6/2026GSA Capital Partners LLP104,378$596K0.0%N/A0.064%
7/9/2026Hennion & Walsh Asset Management Inc.507,050$2.90M0.1%-0.5%0.309%
5/19/2026Bank of America Corp DE4,259,995$23.60M0.0%+165.3%2.600%
5/19/2026Janus Henderson Group PLC59,100$328K0.0%N/A0.036%
5/18/2026ADAR1 Capital Management LLC55,000$305K0.0%+14.6%0.034%
5/18/2026Redmile Group LLC14,549,768$80.61M5.3%+44.8%8.880%
5/16/2026The Manufacturers Life Insurance Company134,786$747K0.0%+3.6%0.082%
5/14/2026Renaissance Technologies LLC544,300$3.02M0.0%-32.2%0.332%
5/14/2026Siren L.L.C.3,958,646$21.93M0.6%N/A2.416%
5/14/2026Sei Investments Co.203,236$1.13M0.0%+248.8%0.124%
5/14/2026Lido Advisors LLC31,000$172K0.0%-11.3%0.019%
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5/7/2026Dimensional Fund Advisors LP924,078$5.12M0.0%+28.6%0.569%
5/7/2026AlphaCentric Advisors LLC24,518$136K0.1%N/A0.015%
5/7/2026Swiss National Bank236,000$1.31M0.0%N/A0.145%
5/5/2026Bank of New York Mellon Corp395,019$2.19M0.0%+9.2%0.243%
5/4/2026J. Safra Sarasin Holding AG90,487$501K0.0%-23.2%0.056%
5/1/2026Fifth Third Bancorp35,398$196K0.0%N/A0.022%
4/28/2026Abel Hall LLC10,921$61K0.0%N/A0.007%
4/27/2026Y Intercept Hong Kong Ltd1,319,913$7.31M0.1%N/A0.812%
4/25/2026Strs Ohio55,500$307K0.0%N/A0.034%
4/22/2026Pictet Asset Management Holding SA16,701$93K0.0%N/A0.010%
3/3/2026Caitong International Asset Management Co. Ltd19,197$96K0.0%N/A0.016%
2/19/2026Invesco Ltd.972,449$4.88M0.0%+381.5%0.813%
2/18/2026Mercer Global Advisors Inc. ADV10,386$52K0.0%N/A0.009%
2/18/2026XTX Topco Ltd243,313$1.22M0.0%+64.6%0.203%
2/18/2026Ikarian Capital LLC230,244$1.16M0.1%N/A0.192%
2/18/2026Virtus Investment Advisers LLC53,527$269K0.1%+27.5%0.045%
2/18/2026Wellington Management Group LLP398,077$2.00M0.0%N/A0.333%
2/18/2026SummitTX Capital L.P.438,497$2.20M0.1%+81.2%0.367%
2/18/2026Susquehanna Portfolio Strategies LLC356,619$1.79M0.0%+0.8%0.298%
2/18/2026Sphera Funds Management LTD.1,316,212$6.61M1.2%-26.6%1.100%
2/18/2026Quadrature Capital Ltd48,573$244K0.0%N/A0.041%
2/18/2026Millennium Management LLC2,836,857$14.24M0.0%+0.5%2.371%
2/18/2026Ishara Investments LP750,000$3.77M4.4%N/A0.627%
2/18/2026Cinctive Capital Management LP358,986$1.80M0.1%+448.4%0.300%
2/18/2026Balyasny Asset Management L.P.3,299,256$16.56M0.0%+154.3%2.758%
2/18/2026Boothbay Fund Management LLC64,069$322K0.0%N/A0.054%
2/18/2026BVF Inc. IL9,128,080$45.82M1.5%+30.4%7.630%
2/17/2026ADAR1 Capital Management LLC48,000$241K0.0%N/A0.040%
2/17/2026Schonfeld Strategic Advisors LLC522,846$2.63M0.0%+146.4%0.437%
2/17/2026J. Goldman & Co LP993,795$4.99M0.1%-10.2%0.831%
2/17/2026AQR Capital Management LLC776,307$3.90M0.0%+35.2%0.649%
2/17/2026Mak Capital One LLC2,958,527$14.85M1.6%N/A2.473%
2/17/2026Jump Financial LLC122,858$617K0.0%N/A0.103%
2/17/2026Price T Rowe Associates Inc. MD445,074$2.24M0.0%-8.2%0.372%
2/17/2026Adage Capital Partners GP L.L.C.5,500,000$27.61M0.0%+266.7%4.598%
2/17/2026Russell Investments Group Ltd.683,016$3.43M0.0%+3,648.7%0.571%
2/17/2026Captrust Financial Advisors31,585$159K0.0%N/A0.026%
2/16/2026Mariner LLC31,335$157K0.0%N/A0.026%
2/16/2026Landscape Capital Management L.L.C.10,016$50K0.0%N/A0.008%
2/16/2026Barclays PLC289,963$1.46M0.0%+96.0%0.242%
2/13/2026Marshall Wace LLP520,998$2.62M0.0%N/A0.436%
2/13/2026The Manufacturers Life Insurance Company 130,102$655K0.0%-1.9%0.109%
2/13/2026Quarry LP75,000$376K0.1%-31.8%0.063%
2/13/2026Jacobs Levy Equity Management Inc.683,879$3.43M0.0%+2,927.5%0.572%
2/13/2026Sirios Capital Management L P710,256$3.57M0.4%-26.8%0.594%
2/13/2026Rafferty Asset Management LLC141,644$711K0.0%N/A0.118%
2/13/2026Charles Schwab Investment Management Inc.1,057,060$5.31M0.0%+33.8%0.884%
2/13/2026State Street Corp4,652,185$23.35M0.0%+126.9%3.889%
2/13/2026Ieq Capital LLC182,982$919K0.0%+21.7%0.153%
2/13/2026Caitong International Asset Management Co. Ltd16,415$82K0.2%N/A0.014%
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2/13/2026Wells Fargo & Company MN573,748$2.88M0.0%+40.1%0.480%
2/12/2026MetLife Investment Management LLC39,059$196K0.0%-12.5%0.033%
2/12/2026Renaissance Technologies LLC802,600$4.03M0.0%+6.5%0.671%
2/12/2026Dimensional Fund Advisors LP718,680$3.61M0.0%-6.3%0.601%
2/12/2026EntryPoint Capital LLC42,774$215K0.1%+114.2%0.036%
2/12/2026New York State Common Retirement Fund29,568$148K0.0%-14.2%0.025%
2/12/2026Nuveen LLC2,915,324$14.64M0.0%+327.1%2.437%
2/11/2026Deutsche Bank AG560,744$2.82M0.0%-62.7%0.469%
2/11/2026Cerity Partners LLC14,801$74K0.0%N/A0.012%
2/11/2026Landing Point Financial Group LLC34,900$175K0.1%N/A0.029%


ANNX Institutional Ownership - Frequently Asked Questions

During the previous two years, 167 institutional investors and hedge funds held shares of Annexon. The most heavily invested institutionals were Redmile Group LLC ($80.61M), BlackRock Inc. ($77.31M), FMR LLC ($50.69M), BVF Inc. IL ($45.82M), Point72 Asset Management L.P. ($28.87M), Adage Capital Partners GP L.L.C. ($27.61M), and Bain Capital Life Sciences Investors LLC ($26.93M).Learn more on Annexon's institutional investors.

Of the 151 institutional investors that purchased Annexon's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($13.54M), State Street Corp ($4.67M), Redmile Group LLC ($4.50M), Adage Capital Partners GP L.L.C. ($4M), Siren L.L.C. ($3.96M), Bank of America Corp DE ($3.68M), and Mak Capital One LLC ($2.96M).

Institutional investors have bought a total of 60,356,954 shares in the last 24 months. This purchase volume represents approximately $316.89M in transactions.

Of the 31 institutional investors that sold Annexon's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Deutsche Bank AG ($943.61K), Goldman Sachs Group Inc. ($637.69K), Opaleye Management Inc. ($617.31K), Sphera Funds Management LTD. ($478.18K), J. Safra Sarasin Holding AG ($290.95K), Sirios Capital Management L P ($279.32K), and Renaissance Technologies LLC ($258.30K).

Institutional investors have sold a total of 4,681,890 shares in the last 24 months. This volume of shares sold represents approximately $22.37M in transactions.



Institutional ownership data for NASDAQ:ANNX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.
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