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Structure Therapeutics (GPCR) Institutional Ownership

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$22.31 -1.60 (-6.69%)
Closing price 04:00 PM Eastern
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$22.31 0.00 (0.00%)
As of 07:59 PM Eastern
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Institutional Ownership Changes (13F Filings) for Structure Therapeutics (NASDAQ:GPCR)

Current
Institutional Ownership
Percentage
91.78%
Number of
Institutional Buyers
(last 12 months)
121
Total
Institutional Inflows
(last 12 months)
$1.05B
Number of
Institutional Sellers
(last 12 months)
62
Total
Institutional Outflows
(last 12 months)
$491.11M
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GPCR Institutional Buying and Selling by Quarter

Structure Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
9/9/2026IFP Advisors Inc858$46K0.0%N/A0.001%
9/9/2026Squarepoint Ops LLC125,575$6.74M0.0%+454.5%0.180%
8/22/2026Seven Fleet Capital Management LP26,800$1.44M0.2%+197.8%0.038%
8/19/2026Wellington Management Group LLP7,379,433$396.05M0.1%+1.6%10.599%
7/10/2026E. Ohman J or Asset Management AB3,212$172K0.0%-28.9%0.005%
7/10/2026Handelsbanken Fonder AB19,400$1.04M0.0%N/A0.027%
6/4/2026Seven Fleet Capital Management LP9,000$434K0.1%N/A0.013%
5/28/2026Avidity Partners Management LP30,000$1.45M0.3%N/A0.042%
5/19/2026Flax Pond Capital LLC36,000$1.74M1.4%-26.1%0.051%
5/19/2026Bank of America Corp DE227,132$10.95M0.0%+617.0%0.321%
5/19/2026Stempoint Capital LP200,267$9.65M1.8%-43.0%0.283%
5/19/2026Janus Henderson Group PLC5,354,981$258.26M0.1%+5.2%7.559%
5/18/2026Royal Bank of Canada722$35K0.0%-92.9%0.001%
5/18/2026Rock Springs Capital Management LP640,217$30.86M1.8%-14.4%0.904%
5/18/2026Eversept Partners LP138,036$6.65M0.4%+8.2%0.195%
5/16/2026The Manufacturers Life Insurance Company114,814$5.53M0.0%+19.1%0.162%
5/16/2026Orbimed Advisors LLC1,475,403$71.11M1.3%+27.0%2.083%
5/15/2026Quadcap Wealth Management LLC4,729$228K0.0%-36.8%0.007%
5/14/2026Renaissance Technologies LLC55,800$2.69M0.0%-51.6%0.079%
5/14/2026PSquared Asset Management AG35,000$1.69M0.6%N/A0.049%
5/14/2026Siren L.L.C.1,328,698$64.04M1.8%+23.2%1.876%
5/14/2026Sei Investments Co.13,990$674K0.0%-6.1%0.020%
5/14/2026Monashee Investment Management LLC50,000$2.41M1.3%-77.8%0.071%
5/13/2026Cetera Investment Advisers7,720$372K0.0%+17.0%0.011%
5/8/2026PNC Financial Services Group Inc.2,854$138K0.0%-27.3%0.004%
5/7/2026SEB Asset Management AB245,043$11.81M0.1%N/A0.346%
5/6/2026Assetmark Inc.2,544$123K0.0%+21.4%0.004%
5/4/2026Principal Financial Group Inc.1,753,764$84.53M0.0%+36.6%2.476%
4/24/2026Peregrine Capital Management LLC97,117$4.68M0.2%+15.2%0.137%
4/22/2026Janney Montgomery Scott LLC6,819$329K0.0%N/A0.010%
4/22/2026Sterling Capital Management LLC590$28K0.0%N/A0.001%
4/20/2026TrueMark Investments LLC34,377$1.66M0.3%+1.4%0.049%
4/16/2026SG Americas Securities LLC2,649$128K0.0%-73.9%0.004%
3/12/2026PEAK6 LLC7,955$553K0.0%N/A0.011%
3/9/2026Flax Pond Capital LLC48,721$3.39M2.5%N/A0.069%
2/19/2026Invesco Ltd.3,200$223K0.0%-99.3%0.005%
2/18/2026XTX Topco Ltd19,193$1.34M0.0%N/A0.032%
2/18/2026Ikarian Capital LLC4,824$336K0.0%-97.0%0.008%
2/18/2026Voloridge Investment Management LLC250,000$17.39M0.1%N/A0.412%
2/18/2026Vestal Point Capital LP35,000$2.43M0.1%N/A0.058%
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2/18/2026Virtus Investment Advisers LLC3,967$276K0.1%-22.5%0.007%
2/18/2026Wellington Management Group LLP7,121,984$495.33M0.2%+25.2%11.737%
2/18/2026SummitTX Capital L.P.94,671$6.58M0.2%N/A0.156%
2/18/2026Susquehanna Portfolio Strategies LLC68,089$4.74M0.1%+21.7%0.112%
2/18/2026Tudor Investment Corp ET AL35,053$2.44M0.0%N/A0.058%
2/18/2026Sphera Funds Management LTD.41,000$2.85M0.5%-81.7%0.068%
2/18/2026Quadrature Capital Ltd12,761$888K0.0%N/A0.021%
2/18/2026RTW Investments LP100,000$6.96M0.1%N/A0.165%
2/18/2026Orbimed Advisors LLC1,161,803$80.80M1.7%+2.0%1.915%
2/18/2026Millennium Management LLC152,560$10.61M0.0%-88.0%0.251%
2/18/2026Janus Henderson Group PLC5,090,148$354.01M0.2%+14.4%8.389%
2/18/2026EcoR1 Capital LLC334,380$23.26M1.1%N/A0.551%
2/18/2026Eversept Partners LP127,561$8.87M0.4%-23.3%0.210%
2/18/2026Capitolis Liquid Global Markets LLC878,300$61.09M0.4%N/A1.243%
2/18/2026Casdin Capital LLC1,175,000$81.72M5.1%-24.4%1.936%
2/18/2026Catalio Capital Management LP252,901$17.59M3.3%-61.2%0.417%
2/18/2026Balyasny Asset Management L.P.216,199$15.04M0.0%-53.2%0.356%
2/18/2026Baker BROS. Advisors LP1,432,529$99.63M0.6%-7.9%2.361%
2/18/2026BVF Inc. IL3,479,022$241.97M8.2%+8.6%5.733%
2/18/2026ACT Capital Management LLC38,500$2.68M2.2%N/A0.063%
2/17/2026Logos Global Management LP600,000$41.73M2.5%-29.4%0.989%
2/17/2026Schonfeld Strategic Advisors LLC8,727$607K0.0%N/A0.014%
2/17/2026Burkehill Global Management LP60,000$4.17M0.3%N/A0.099%
2/17/2026J. Goldman & Co LP13,601$946K0.0%N/A0.022%
2/17/2026Cetera Investment Advisers6,596$459K0.0%N/A0.011%
2/17/2026Jain Global LLC99,996$6.96M0.0%N/A0.165%
2/17/2026ArrowMark Colorado Holdings LLC271,213$18.86M0.4%-16.1%0.447%
2/17/2026Trexquant Investment LP89,945$6.26M0.1%+345.4%0.148%
2/17/2026Farallon Capital Management LLC454,000$31.58M0.1%N/A0.748%
2/17/2026Price T Rowe Associates Inc. MD1,671,138$116.23M0.0%+477.5%2.754%
2/17/2026Rock Springs Capital Management LP748,236$52.04M2.7%-21.3%1.233%
2/17/2026Osaic Holdings Inc.59,238$4.12M0.0%-5.7%0.098%
2/17/2026Integral Health Asset Management LLC50,000$3.48M0.2%N/A0.082%
2/17/2026Russell Investments Group Ltd.26,274$1.83M0.0%N/A0.043%
2/17/2026B Group Inc.90,000$6.26M4.6%N/A0.148%
2/17/2026Avoro Capital Advisors LLC6,555,555$455.94M4.4%+21.3%9.254%
2/16/2026Verition Fund Management LLC78,149$5.44M0.0%+98.6%0.129%
2/16/2026PEAK6 LLC7,955$553K0.0%N/A0.013%
2/16/2026MML Investors Services LLC7,825$544K0.0%N/A0.013%
2/16/2026Maven Securities LTD20,000$1.39M0.0%N/A0.033%
2/16/2026NEXTBio Capital Management LP94,443$6.57M3.9%N/A0.156%
2/16/2026Healthcare of Ontario Pension Plan Trust Fund467,800$32.54M0.1%N/A0.771%
2/16/2026Barclays PLC7,833$545K0.0%+107.6%0.013%
2/13/2026Marshall Wace LLP168,584$11.73M0.0%N/A0.278%
2/13/2026The Manufacturers Life Insurance Company 96,387$6.53M0.0%+237.8%0.159%
2/13/2026Quinn Opportunity Partners LLC25,000$1.74M0.1%-40.5%0.041%
2/13/2026Stifel Financial Corp4,830$336K0.0%N/A0.008%
2/13/2026Bleichroeder LP10,000$696K0.1%-50.0%0.016%
2/13/2026Morgan Stanley2,087,834$145.21M0.0%+261.4%3.441%
2/13/2026Brandywine Managers LLC13,357$929K0.5%+20.8%0.022%
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2/13/2026Headlands Technologies LLC43,729$3.04M0.3%+63.1%0.072%
2/13/2026Birchview Capital LP90,000$6.26M3.7%+15.4%0.148%
2/13/2026Alyeska Investment Group L.P.115,000$8.00M0.0%-53.0%0.190%
2/13/2026Siren L.L.C.1,078,698$75.02M2.2%+5.1%1.778%
2/13/2026Police & Firemen s Retirement System of New Jersey1,829$127K0.0%N/A0.003%
2/13/2026State Street Corp48,224$3.35M0.0%+4.8%0.079%
2/13/2026Wells Fargo & Company MN5,664$394K0.0%-6.5%0.009%
2/13/2026Platinum Investment Management Ltd.87,874$6.11M1.4%-28.4%0.145%
2/13/2026Rhenman & Partners Asset Management AB147,600$10.27M1.0%-18.0%0.243%
2/12/2026Renaissance Technologies LLC115,200$8.01M0.0%-25.1%0.190%


GPCR Institutional Ownership - Frequently Asked Questions

During the previous two years, 211 institutional investors and hedge funds held shares of Structure Therapeutics. The most heavily invested institutionals were Avoro Capital Advisors LLC ($455.94M), Wellington Management Group LLP ($396.05M), Janus Henderson Group PLC ($258.26M), BVF Inc. IL ($241.97M), FMR LLC ($164.86M), Morgan Stanley ($145.21M), and Deep Track Capital LP ($118.04M).Learn more on Structure Therapeutics' institutional investors.

91.78% of Structure Therapeutics' stock is owned by institutional investors. Learn more on GPCR's institutional investor holdings.

Of the 191 institutional investors that purchased Structure Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Wellington Management Group LLP ($1.80M), Janus Henderson Group PLC ($1.71M), Principal Financial Group Inc. ($1.59M), Deep Track Capital LP ($1.58M), Morgan Stanley ($1.51M), Price T Rowe Associates Inc. MD ($1.38M), and Vestal Point Capital LP ($1.26M).

Institutional investors have bought a total of 17,576,433 shares in the last 24 months. This purchase volume represents approximately $1.05B in transactions.

Of the 62 institutional investors that sold Structure Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Wellington Management Group LLP ($1.19M), Millennium Management LLC ($1.12M), Baker BROS. Advisors LP ($1.08M), Deep Track Capital LP ($918.11K), Federated Hermes Inc. ($463.80K), Invesco Ltd. ($440.54K), and Monashee Investment Management LLC ($405K).

Institutional investors have sold a total of 10,121,699 shares in the last 24 months. This volume of shares sold represents approximately $491.11M in transactions.


Related Companies

Institutional ownership data for NASDAQ:GPCR is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.
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