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Pyxis Oncology (PYXS) Institutional Ownership

Pyxis Oncology logo
$3.33 -0.08 (-2.35%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$3.40 +0.07 (+2.16%)
As of 09/18/2026 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Pyxis Oncology (NASDAQ:PYXS)

Current
Institutional Ownership
Percentage
39.07%
Number of
Institutional Buyers
(last 12 months)
31
Total
Institutional Inflows
(last 12 months)
$9.01M
Number of
Institutional Sellers
(last 12 months)
13
Total
Institutional Outflows
(last 12 months)
$8.01M
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PYXS Institutional Buying and Selling by Quarter

Pyxis Oncology Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/21/2026 J. Derek Lewis & Associates Inc.43,000$63K0.0%-18.9%0.068%
5/19/2026 Bank of America Corp DE16,807$25K0.0%-97.1%0.027%
5/14/2026 Renaissance Technologies LLC888,680$1.30M0.0%+22.0%1.414%
5/7/2026 Dimensional Fund Advisors LP25,912$38K0.0%-48.2%0.041%
5/5/2026 Bank of New York Mellon Corp133,996$196K0.0%-18.8%0.213%
3/23/2026 J. Derek Lewis & Associates Inc.53,000$61K0.0%N/A0.085%
2/18/2026 XTX Topco Ltd289,033$332K0.0%+1,533.0%0.464%
2/18/2026 Toronto Dominion Bank75,000$86K0.0%N/A0.120%
2/18/2026 Quadrature Capital Ltd100,536$116K0.0%N/A0.161%
2/18/2026 Millennium Management LLC743,107$855K0.0%-8.9%1.194%
2/18/2026 Maia Wealth LLC21,959$25K0.0%N/A0.035%
2/18/2026 Engineers Gate Manager LP22,816$26K0.0%N/A0.037%
2/18/2026 683 Capital Management LLC891,910$1.03M0.0%+69.9%1.433%
2/17/2026 Laurion Capital Management LP4,796,479$5.52M0.2%+32.3%7.703%
2/17/2026 ExodusPoint Capital Management LP317,769$365K0.0%N/A0.510%
2/17/2026 Royal Bank of Canada55,551$64K0.0%-28.8%0.089%
2/17/2026 Graham Capital Management L.P.183,942$212K0.0%N/A0.295%
2/16/2026 OMERS ADMINISTRATION Corp67,000$77K0.0%N/A0.108%
2/16/2026 Barclays PLC60,385$69K0.0%+1,939.3%0.097%
2/13/2026 Marshall Wace LLP389,764$448K0.0%N/A0.626%
2/13/2026 Velan Capital Investment Management LP40,000$46K0.0%-27.3%0.064%
2/13/2026 State Street Corp241,637$278K0.0%+19.6%0.388%
2/12/2026 Jane Street Group LLC786,010$904K0.0%+158.8%1.262%
2/12/2026 HRT Financial LP39,649$45K0.0%+157.5%0.064%
2/12/2026 Commonwealth Equity Services LLC39,755$46K0.0%-35.0%0.064%
2/12/2026 Renaissance Technologies LLC728,380$838K0.0%+26.4%1.170%
2/12/2026 Dimensional Fund Advisors LP50,066$58K0.0%+37.1%0.080%
2/11/2026 Fox Run Management L.L.C.22,566$26K0.0%N/A0.036%
2/11/2026 LPL Financial LLC35,102$40K0.0%+150.7%0.056%
2/10/2026 Goldman Sachs Group Inc.86,145$99K0.0%-31.3%0.138%
2/9/2026 Geode Capital Management LLC577,211$664K0.0%+6.0%0.927%
2/6/2026 Atle Fund Management AB617,245$710K0.2%N/A0.991%
1/12/2026 Avanza Fonder AB27,345$31K0.0%N/A0.044%
11/17/2025 Jacobs Levy Equity Management Inc.60,333$134K0.0%N/A0.097%
11/17/2025 Velan Capital Investment Management LP55,000$122K0.1%+37.5%0.088%
11/17/2025 Qube Research & Technologies Ltd30,808$68K0.0%-70.1%0.049%
11/17/2025 Millennium Management LLC815,331$1.81M0.0%-77.0%1.309%
11/17/2025 Citadel Advisors LLC337,359$749K0.0%N/A0.542%
11/17/2025 Bank of America Corp DE615,922$1.37M0.0%+2,690.9%0.989%
11/14/2025 Longaeva Partners L.P.503,214$1.12M0.2%N/A0.808%
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11/14/2025 Two Sigma Investments LP46,501$103K0.0%N/A0.075%
11/14/2025 Bridgeway Capital Management LLC76,700$170K0.0%-46.1%0.123%
11/13/2025 UBS Group AG373,727$830K0.0%-5.6%0.600%
11/10/2025 Persistent Asset Partners Ltd34,632$77K0.1%N/A0.056%
11/7/2025Vanguard Group Inc.2,163,962$4.80M0.0%+0.7%3.476%
10/31/2025 Pier 88 Investment Partners LLC151,730$337K0.1%-58.7%0.245%
8/15/2025 Bridgeway Capital Management LLC142,295$157K0.0%+76.1%0.230%
8/14/2025 Jane Street Group LLC336,084$370K0.0%N/A0.543%
8/14/2025 Velan Capital Investment Management LP40,000$44K0.0%N/A0.065%
8/14/2025 Qube Research & Technologies Ltd103,063$113K0.0%+128.4%0.166%
8/13/2025 Marshall Wace LLP147,771$163K0.0%N/A0.239%
8/12/2025 XTX Topco Ltd36,380$40K0.0%N/A0.059%
8/12/2025 Catalyst Funds Management Pty Ltd23,200$26K0.0%N/A0.037%
8/8/2025 Geode Capital Management LLC510,963$562K0.0%-53.9%0.825%
8/7/2025 Pier 88 Investment Partners LLC367,170$404K0.1%-6.1%0.593%
8/1/2025 Y Intercept Hong Kong Ltd133,047$146K0.0%N/A0.215%
7/30/2025 Schulhoff & Co. Inc.275,000$302K0.1%+125.4%0.444%
7/11/2025 Kingstone Capital Partners Texas LLC33,600$37K0.0%N/A0.054%
6/27/2025 Goldman Sachs Group Inc.160,830$158K0.0%-12.9%0.260%
5/21/2025Acadian Asset Management LLC84,122$81K0.0%N/A0.136%
5/16/2025Goldman Sachs Group Inc.160,830$158K0.0%-12.9%0.260%
5/16/2025AQR Capital Management LLC40,270$39K0.0%-19.6%0.065%
5/16/2025683 Capital Management LLC550,000$539K0.0%+32.5%0.888%
5/13/2025American Century Companies Inc.26,353$26K0.0%-91.2%0.043%
5/12/2025Nuveen LLC127,304$125K0.0%N/A0.206%
5/9/2025Charles Schwab Investment Management Inc.115,237$113K0.0%-11.2%0.186%
5/6/2025Pier 88 Investment Partners LLC390,960$383K0.1%+296.6%0.631%
2/17/2025Ridgeback Capital Investments L.P.359,231$560K100.0%N/A0.604%
2/17/2025ProShare Advisors LLC16,568$26K0.0%N/A0.028%
2/17/2025Nuveen Asset Management LLC127,304$199K0.0%-14.6%0.214%
2/17/2025OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC146,400$228K0.0%N/A0.246%
2/17/2025Millennium Management LLC2,980,906$4.65M0.0%+53.8%5.012%
2/17/2025Jacobs Levy Equity Management Inc.601,940$939K0.0%+57.2%1.012%
2/17/2025Graham Capital Management L.P.30,287$47K0.0%N/A0.051%
2/17/2025Deutsche Bank AG30,300$47K0.0%-87.3%0.051%
2/17/2025Caption Management LLC22,306$35K0.0%N/A0.038%
2/17/2025Bank of America Corp DE53,745$84K0.0%+20.3%0.090%
2/17/2025Ameriprise Financial Inc.22,251$35K0.0%N/A0.037%
2/14/2025Jane Street Group LLC67,686$106K0.0%+36.6%0.114%
2/14/2025Northern Trust Corp378,586$591K0.0%-3.9%0.637%
2/14/2025Boothbay Fund Management LLC181,042$282K0.0%-52.7%0.304%
2/14/2025Dimensional Fund Advisors LP111,051$173K0.0%+35.5%0.187%
2/13/2025Marshall Wace LLP157,953$246K0.0%+35.7%0.266%
2/13/2025XTX Topco Ltd22,492$35K0.0%-73.5%0.038%
2/13/2025Barclays PLC77,013$121K0.0%+20.2%0.129%
2/13/2025Renaissance Technologies LLC293,354$458K0.0%+83.0%0.493%
2/13/2025Aristides Capital LLC124,000$193K0.0%N/A0.209%
2/12/2025Pier 88 Investment Partners LLC98,590$154K0.0%-18.9%0.166%
2/11/2025Sei Investments Co.61,140$95K0.0%N/A0.103%
2/11/2025American Century Companies Inc.299,937$468K0.0%+88.1%0.504%
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2/10/2025Commonwealth Equity Services LLC26,250$41K0.0%+61.5%0.044%
11/19/2024Barclays PLC64,089$235K0.0%+275.0%0.108%
11/16/2024Geode Capital Management LLC1,084,727$3.98M0.0%+5.5%1.824%
11/15/2024Barclays PLC64,089$235K0.0%+275.0%0.108%
11/15/2024Public Employees Retirement System of Ohio29,100$107K0.0%N/A0.049%
11/15/2024XTX Topco Ltd84,771$311K0.0%+133.6%0.143%
11/15/2024Jane Street Group LLC49,558$182K0.0%+40.8%0.083%
11/15/2024State Street Corp951,251$3.49M0.0%+28.0%1.600%
11/15/2024Jacobs Levy Equity Management Inc.382,840$1.41M0.0%N/A0.644%
11/14/2024MetLife Investment Management LLC18,818$69K0.0%+41.1%0.032%


PYXS Institutional Ownership - Frequently Asked Questions

During the previous two years, 66 institutional investors and hedge funds held shares of Pyxis Oncology. The most heavily invested institutionals were Laurion Capital Management LP ($5.52M), Vanguard Group Inc. ($4.80M), abrdn plc ($3.35M), Renaissance Technologies LLC ($1.30M), Longaeva Partners L.P. ($1.12M), 683 Capital Management LLC ($1.03M), and Jane Street Group LLC ($904K).Learn more on Pyxis Oncology's institutional investors.

39.07% of Pyxis Oncology's stock is owned by institutional investors. Learn more on PYXS's institutional investor holdings.

Of the 56 institutional investors that purchased Pyxis Oncology's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Laurion Capital Management LP ($1.17M), Millennium Management LLC ($1.04M), Jane Street Group LLC ($850.87K), Jacobs Levy Equity Management Inc. ($662.27K), Atle Fund Management AB ($617.25K), Bank of America Corp DE ($602.92K), and Marshall Wace LLP ($579.13K).

Institutional investors have bought a total of 6,296,413 shares in the last 24 months. This purchase volume represents approximately $9.01M in transactions.

Of the 13 institutional investors that sold Pyxis Oncology's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Millennium Management LLC ($2.80M), Bank of America Corp DE ($571.04K), Pier 88 Investment Partners LLC ($215.44K), Qube Research & Technologies Ltd ($72.26K), Bridgeway Capital Management LLC ($65.60K), Goldman Sachs Group Inc. ($39.31K), and Bank of New York Mellon Corp ($31.05K).

Institutional investors have sold a total of 3,906,796 shares in the last 24 months. This volume of shares sold represents approximately $8.01M in transactions.


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Institutional ownership data for NASDAQ:PYXS is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 5/21/2026. New 13F filings are added each quarter as they're published.
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