Milestone Scientific (MLSS) Stock Price, News & Analysis

Company Overview

Milestone Scientific, Inc., listed on the New York Stock Exchange under the symbol MLSS, is a medical device company specializing in the development and commercialization of computer-controlled injection technologies for local anesthesia and pain management. The company’s proprietary systems are designed to enhance patient comfort, improve clinical outcomes and streamline the administration of anesthetics in dental and medical procedures. Through its precision delivery platforms, Milestone Scientific aims to set a new standard for minimally invasive injections.

At the core of Milestone Scientific’s product portfolio is the Single Tooth Anesthesia (STA) System, which uses Comunication Controlled Local Anesthetic Delivery (CCLAD) technology to provide targeted, atraumatic anesthesia for individual dental roots. Complementing STA is the CompuFlo® Epidural System, which employs real-time pressure sensing to identify tissue planes and facilitate safer, more accurate epidural needle placement. Both systems are supported by a growing body of clinical research, patents and peer-reviewed publications that underscore their efficacy and safety.

Milestone Scientific distributes its technologies through a combination of direct sales and partnerships with dental and medical distributors, serving markets across North America, Europe, Latin America and parts of Asia. The company maintains strategic relationships with dental institutions, hospitals and specialty clinics to drive adoption and training. In addition to product sales, Milestone offers continuing education programs for clinicians, ensuring that users are proficient in device operation and best practices for pain management.

Founded in 1995 and headquartered in Livingston, New Jersey, Milestone Scientific was established to bridge the gap between conventional syringe techniques and modern computer-aided delivery systems. The company’s leadership team brings together experience in medical device development, regulatory affairs and commercial strategy to support global expansion and ongoing innovation. Through sustained investment in research and development, Milestone Scientific continues to advance its platform technologies and explore new applications in both dental and medical markets.

Key Stats

• Today's Range: $0.45 to $0.45
• 50-Day Range: $0.43 to $0.65
• 52-Week Range: $0.38 to $1.39
• Volume: 147,264 shs
• Average Volume: 197,223 shs
• Market Capitalization: $35.50 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $1.25
• Consensus Rating: Buy

Milestone Scientific Stock Analysis - MarketRank™

Milestone Scientific scored higher than 58% of companies evaluated by MarketBeat, and ranked 449th out of 942 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.5 / 5
• Analyst Rating: Buy

Consensus Rating

Milestone Scientific has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 1 buy rating, no hold ratings, and no sell ratings.

Upside Potential

Milestone Scientific has a consensus price target of $1.25, representing about 176.6% upside from its current price of $0.45.

Amount of Analyst Coverage

Milestone Scientific has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: N/A

Price to Earnings Ratio vs. the Market

The P/E ratio of Milestone Scientific is -6.45, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Milestone Scientific is -6.45, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Milestone Scientific has a P/B Ratio of 4.11. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 5.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

0.26% of the float of Milestone Scientific has been sold short.

Short Interest Ratio / Days to Cover

Milestone Scientific has a short interest ratio ("days to cover") of 0.4, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Milestone Scientific has recently decreased by 29.94%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Milestone Scientific does not currently pay a dividend.

Dividend Growth

Milestone Scientific does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

0.26% of the float of Milestone Scientific has been sold short.

Short Interest Ratio / Days to Cover

Milestone Scientific has a short interest ratio ("days to cover") of 0.4, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Milestone Scientific has recently decreased by 29.94%, indicating that investor sentiment is improving significantly.

News and Social Media

• Score: N/A
• News Sentiment: N/A

Company Ownership

• Score: 2.5 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Milestone Scientific insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $20,227.00 in company stock.

Percentage Held by Insiders

24.75% of the stock of Milestone Scientific is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

Only 5.79% of the stock of Milestone Scientific is held by institutions.

MLSS Stock Analysis - Frequently Asked Questions

How have MLSS shares performed this year?

Milestone Scientific's stock was trading at $0.96 at the beginning of 2025. Since then, MLSS shares have decreased by 52.9% and is now trading at $0.4519.

How were Milestone Scientific's earnings last quarter?

Milestone Scientific Inc. (NYSE:MLSS) released its earnings results on Thursday, August, 15th. The company reported ($0.02) earnings per share for the quarter, missing analysts' consensus estimates of ($0.01) by $0.01. The company earned $1.85 million during the quarter. Milestone Scientific had a negative trailing twelve-month return on equity of 60.26% and a negative net margin of 52.01%.

How do I buy shares of Milestone Scientific?

Shares of MLSS stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Milestone Scientific own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Milestone Scientific investors own include Waste Connections (WCN), DiamondRock Hospitality (DRH), The RMR Group (RMR), AU Optronics (AUOTY), iShares Micro-Cap ETF (IWC), American Water Works (AWK) and Triple Flag Precious Metals (TFPM).

Company Calendar

• Last Earnings: 8/15/2024
• Today: 10/07/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NYSE
• Sector: Medical
• Industry: Surgical appliances & supplies
• Sub-Industry: Medical Equipment
• Current Symbol: NYSE:MLSS
• CIK: 855683
• Web: www.milestonescientific.com
• Phone: (973) 535-2717
• Fax: 973-535-2829
• Employees: 30
• Year Founded: 1989

Price Target and Rating

• Average Price Target for Milestone Scientific: $1.25
• High Price Target: $1.25
• Low Price Target: $1.25
• Potential Upside/Downside: +176.6%
• Consensus Rating: Buy
• Rating Score (0-4): 3.00
• Research Coverage: 1 Analysts

Profitability

• EPS (Trailing Twelve Months): ($0.09)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$6.93 million
• Net Margins: -52.01%
• Pretax Margin: -52.21%
• Return on Equity: -60.26%
• Return on Assets: -40.23%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 2.85
• Quick Ratio: 1.86

Sales & Book Value

• Annual Sales: $9.08 million
• Price / Sales: 3.91
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $0.11 per share
• Price / Book: 4.11

Miscellaneous

• Outstanding Shares: 78,559,000
• Free Float: 58,614,000
• Market Cap: $35.50 million
• Optionable: Optionable
• Beta: 0.88