Mersana Therapeutics (MRSN) Stock Price, News & Analysis

Company Overview

Mersana Therapeutics, Inc., a clinical stage biopharmaceutical company, develops antibody drug conjugates (ADC) for cancer patients with unmet needs. The company develops XMT-1660, a B7-H4-targeted Dolasynthen ADC candidate; and XMT-2056, an immunosynthen ADC. It has research and development collaborations with Janssen Biotech, Inc., Ares Trading S.A., Merck KGaA, and Asana BioSciences, LLC for the development of ADC product candidates. The company was formerly known as Nanopharma Corp. and changed its name to Mersana Therapeutics, Inc. in November 2005. Mersana Therapeutics, Inc. was incorporated in 2001 and is headquartered in Cambridge, Massachusetts.

Key Stats

• Today's Range: $0.34 to $0.39
• 50-Day Range: $0.26 to $0.46
• 52-Week Range: $0.26 to $2.83
• Volume: 3.13 million shs
• Average Volume: 2.59 million shs
• Market Capitalization: $43.91 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $5.20
• Consensus Rating: Buy

Mersana Therapeutics Stock Analysis - MarketRank™

Mersana Therapeutics scored higher than 76% of companies evaluated by MarketBeat, and ranked 241st out of 919 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.5 / 5
• Analyst Rating: Buy

Consensus Rating

Mersana Therapeutics has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 5 buy ratings, 1 hold rating, and no sell ratings.

Amount of Analyst Coverage

Mersana Therapeutics has only been the subject of 3 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Mersana Therapeutics are expected to decrease in the coming year, from ($0.62) to ($0.67) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Mersana Therapeutics is -0.58, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Mersana Therapeutics is -0.58, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Mersana Therapeutics has a P/B Ratio of 1.14. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

8.45% of the outstanding shares of Mersana Therapeutics have been sold short.

Short Interest Ratio / Days to Cover

Mersana Therapeutics has a short interest ratio ("days to cover") of 3.4, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Mersana Therapeutics has recently increased by 4.67%, indicating that investor sentiment is decreasing.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Mersana Therapeutics does not currently pay a dividend.

Dividend Growth

Mersana Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.1 / 5
• Environmental Score: -0.69

Percentage of Shares Shorted

8.45% of the outstanding shares of Mersana Therapeutics have been sold short.

Short Interest Ratio / Days to Cover

Mersana Therapeutics has a short interest ratio ("days to cover") of 3.4, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Mersana Therapeutics has recently increased by 4.67%, indicating that investor sentiment is decreasing.

News and Social Media

• Score: 2.5 / 5
• News Sentiment: 0.48

News Sentiment

Mersana Therapeutics has a news sentiment score of 0.48. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.73 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 12 news articles for Mersana Therapeutics this week, compared to 2 articles on an average week.

Search Interest

16 people have searched for MRSN on MarketBeat in the last 30 days. This is an increase of 45% compared to the previous 30 days.

MarketBeat Follows

Only 5 people have added Mersana Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of -17% compared to the previous 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Mersana Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

13.00% of the stock of Mersana Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

93.92% of the stock of Mersana Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

MRSN Stock Analysis - Frequently Asked Questions

How have MRSN shares performed this year?

Mersana Therapeutics' stock was trading at $1.43 at the beginning of 2025. Since then, MRSN shares have decreased by 75.4% and is now trading at $0.3523.
View the best growth stocks for 2025 here.

How were Mersana Therapeutics' earnings last quarter?

Mersana Therapeutics, Inc. (NASDAQ:MRSN) issued its quarterly earnings data on Thursday, May, 15th. The company reported ($0.19) earnings per share (EPS) for the quarter, beating analysts' consensus estimates of ($0.21) by $0.02. The company earned $2.75 million during the quarter, compared to analyst estimates of $6.05 million. Mersana Therapeutics had a negative net margin of 214.20% and a negative trailing twelve-month return on equity of 401.37%.
Read the conference call transcript.

When did Mersana Therapeutics IPO?

Mersana Therapeutics (MRSN) raised $75 million in an initial public offering on Wednesday, June 28th 2017. The company issued 5,000,000 shares at $14.00-$16.00 per share. J.P. Morgan, Cowen and Leerink Partners acted as the underwriters for the IPO and Wedbush PacGrow was co-manager.

Who are Mersana Therapeutics' major shareholders?

Top institutional shareholders of Mersana Therapeutics include AQR Capital Management LLC (4.13%), Acadian Asset Management LLC (2.40%), 683 Capital Management LLC (1.32%) and Jacobs Levy Equity Management Inc. (1.07%). Insiders that own company stock include Andrew A F Hack, Timothy B Lowinger, Anna Protopapas, Martin H Jr Huber, Brian Deschuytner, Alejandra Carvajal, Ashish Mandelia, Mohan Bala, Arvin Yang and Tushar Misra.
View institutional ownership trends.

How do I buy shares of Mersana Therapeutics?

Shares of MRSN stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Mersana Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Mersana Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Broadcom (AVGO), Saia (SAIA), Rambus (RMBS), Advanced Micro Devices (AMD) and Arista Networks (ANET).

Company Calendar

• Last Earnings: 5/15/2025
• Today: 5/24/2025
• Next Earnings (Estimated): 8/12/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: Pharmaceutical preparations
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:MRSN
• CIK: 1442836
• Web: www.mersana.com
• Phone: (617) 498-0020
• Fax: N/A
• Employees: 150
• Year Founded: N/A

Price Target and Rating

• Average Stock Price Target: $5.20
• High Stock Price Target: $10.00
• Low Stock Price Target: $3.00
• Potential Upside/Downside: +1,376.0%
• Consensus Rating: Buy
• Rating Score (0-4): 3.00
• Research Coverage: 7 Analysts

Profitability

• EPS (Most Recent Fiscal Year): ($0.59)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: $-171,670,000.00
• Net Margins: -214.20%
• Pretax Margin: -212.99%
• Return on Equity: -401.37%
• Return on Assets: -38.61%

Debt

• Debt-to-Equity Ratio: 13.35
• Current Ratio: 2.35
• Quick Ratio: 2.35

Sales & Book Value

• Annual Sales: $34.01 million
• Price / Sales: 1.29
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $0.31 per share
• Price / Book: 1.14

Miscellaneous

• Outstanding Shares: 124,631,000
• Free Float: 108,956,000
• Market Cap: $43.91 million
• Optionable: Optionable
• Beta: 1.32