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Zymeworks (ZYME) Institutional Ownership

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$18.40 -0.15 (-0.81%)
Closing price 10/17/2025 04:00 PM Eastern
Extended Trading
$18.65 +0.25 (+1.36%)
As of 10/17/2025 06:13 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.
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Institutional Ownership Changes (13F Filings) for Zymeworks (NYSE:ZYME)

Current
Institutional Ownership
Percentage
92.89%
Number of
Institutional Buyers
(last 12 months)
90
Total
Institutional Inflows
(last 12 months)
$256.36M
Number of
Institutional Sellers
(last 12 months)
72
Total
Institutional Outflows
(last 12 months)
$3.86B
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Skip Chart & View Institutional Buying and Selling Data

ZYME Institutional Buying and Selling by Quarter

Zymeworks Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
10/15/2025 CWM LLC6,968$119K0.0%-18.7%0.009%
10/7/2025 Assenagon Asset Management S.A.1,326,774$22.66M0.0%+169.2%1.765%
8/27/2025Squarepoint Ops LLC155,599$1.95M0.0%+144.6%0.207%
8/15/2025Tower Research Capital LLC TRC 4,947$62K0.0%+29.6%0.007%
8/15/2025Vestal Point Capital LP1,150,000$14.43M0.8%+130.0%1.530%
8/15/2025Rubric Capital Management LP4,710,551$59.12M0.9%+8.6%6.267%
8/15/2025Opaleye Management Inc.210,000$2.64M0.5%+20.0%0.279%
8/15/2025Perceptive Advisors LLC1,275,274$16.01M1.4%-31.6%1.697%
8/15/2025Man Group plc35,406$444K0.0%+226.1%0.047%
8/15/2025EcoR1 Capital LLC22,970,388$288.28M17.1%+33.1%30.560%
8/15/2025Engineers Gate Manager LP18,941$238K0.0%+52.8%0.025%
8/15/2025BNP Paribas Financial Markets10,307$129K0.0%+157.7%0.014%
8/15/2025Brevan Howard Capital Management LP10,628$133K0.0%N/A0.014%
8/15/2025Bank of America Corp DE90,378$1.13M0.0%+45.5%0.120%
8/15/2025Adage Capital Partners GP L.L.C.476,000$5.97M0.0%N/A0.633%
8/14/2025Samsara Biocapital LLC310,300$3.89M0.8%-53.5%0.413%
8/14/2025Jane Street Group LLC12,549$157K0.0%-90.8%0.017%
8/14/2025California State Teachers Retirement System42,873$538K0.0%-2.1%0.057%
8/14/2025Acuta Capital Partners LLC83,655$1.05M1.5%+22.2%0.111%
8/14/2025Raymond James Financial Inc.124,435$1.56M0.0%+6.6%0.166%
8/14/2025Redmile Group LLC4,150,627$52.09M5.5%-13.3%5.522%
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.26,863$337K0.0%-17.1%0.036%
8/14/2025The Manufacturers Life Insurance Company 19,070$239K0.0%-6.8%0.025%
8/14/2025Squarepoint Ops LLC155,599$1.95M0.0%+144.6%0.207%
8/14/2025Qube Research & Technologies Ltd69,874$877K0.0%N/A0.093%
8/14/2025AXA S.A.175,121$2.20M0.0%N/A0.233%
8/13/2025Cresset Asset Management LLC16,638$209K0.0%-22.0%0.022%
8/13/2025Tema Etfs LLC51,855$651K0.2%+57.1%0.069%
8/13/2025Kennedy Capital Management LLC146,954$1.84M0.0%+7.8%0.196%
8/13/2025Invesco Ltd.89,371$1.12M0.0%+14.3%0.119%
8/13/2025Panagora Asset Management Inc.33,559$421K0.0%N/A0.045%
8/13/2025Schroder Investment Management Group304,666$3.80M0.0%-5.4%0.405%
8/13/2025Virtus Investment Advisers LLC7,178$90K0.0%-44.8%0.010%
8/13/2025Tejara Capital Ltd200,150$2.51M1.2%+5.7%0.266%
8/13/2025Norges Bank201,700$2.53M0.0%N/A0.268%
8/13/2025Hsbc Holdings PLC36,497$461K0.0%N/A0.049%
8/13/2025Russell Investments Group Ltd.28,312$355K0.0%+827.4%0.041%
8/12/2025XTX Topco Ltd31,021$389K0.0%+53.5%0.045%
8/12/2025Prudential Financial Inc.44,965$564K0.0%+5.6%0.065%
8/12/2025Rhumbline Advisers86,083$1.08M0.0%+4.0%0.124%
8/12/2025Legal & General Group Plc43,763$549K0.0%-6.5%0.063%
8/12/2025Hillsdale Investment Management Inc.205,022$2.57M0.1%-13.5%0.294%
8/12/2025JPMorgan Chase & Co.441,690$5.54M0.0%+1,050.0%0.634%
8/12/2025Swiss National Bank73,100$917K0.0%-8.7%0.105%
8/11/2025Universal Beteiligungs und Servicegesellschaft mbH14,300$179K0.0%N/A0.021%
8/8/2025Intech Investment Management LLC23,163$291K0.0%-42.5%0.033%
8/8/2025Creative Planning25,389$319K0.0%+114.8%0.036%
8/7/2025ProShare Advisors LLC12,665$159K0.0%-15.1%0.018%
8/7/2025Campbell & CO Investment Adviser LLC14,985$188K0.0%N/A0.022%
8/6/2025BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,039,656$25.60M0.1%-99.3%2.927%
8/5/2025Bank of Montreal Can27,642$347K0.0%+6.7%0.040%
8/1/2025Teacher Retirement System of Texas10,368$130K0.0%-7.2%0.015%
8/1/2025Envestnet Asset Management Inc.14,606$183K0.0%-70.5%0.021%
7/31/2025AlphaQuest LLC14,026$176K0.0%-55.7%0.020%
7/29/2025VIRGINIA RETIREMENT SYSTEMS ET Al54,075$679K0.0%N/A0.078%
7/28/2025Ritholtz Wealth Management25,235$317K0.0%-58.3%0.036%
7/25/2025 CWM LLC8,570$108K0.0%+272.8%0.012%
7/23/2025KLP Kapitalforvaltning AS7,300$92K0.0%-29.1%0.010%
7/21/2025Platinum Investment Management Ltd.238,391$2.99M0.2%-14.5%0.342%
7/11/2025 Assenagon Asset Management S.A.492,780$6.18M0.0%-0.5%0.707%
6/18/2025 Voya Investment Management LLC15,653$186K0.0%-73.7%0.022%
5/29/2025Rhumbline Advisers82,738$985K0.0%-20.3%0.119%
5/19/2025Jane Street Group LLC135,763$1.62M0.0%+487.0%0.195%
5/19/2025UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC3,879,945$46.21M0.0%+184.2%5.576%
5/16/2025Empowered Funds LLC360,044$4.29M0.1%+2.1%0.517%
5/16/2025Goldman Sachs Group Inc.200,047$2.38M0.0%-20.0%0.288%
5/16/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.32,385$386K0.0%+4.6%0.047%
5/16/2025Jacobs Levy Equity Management Inc.12,040$143K0.0%-96.6%0.017%
5/16/2025Granahan Investment Management LLC407,589$4.85M0.2%-0.9%0.586%
5/16/2025EcoR1 Capital LLC17,259,548$205.56M12.2%+14.8%24.806%
5/16/2025Bridgeway Capital Management LLC766,944$9.13M0.2%+1.0%1.102%
5/16/2025AQR Capital Management LLC48,485$577K0.0%+86.0%0.070%
5/16/2025ADAR1 Capital Management LLC50,000$596K0.1%N/A0.072%
5/15/2025Redmile Group LLC4,788,945$57.04M5.4%-1.1%6.883%
5/15/2025Vestal Point Capital LP500,000$5.96M0.4%+170.3%0.719%
5/15/2025Royal Bank of Canada56,771$676K0.0%-6.8%0.082%
5/15/2025Magnetar Financial LLC12,448$148K0.0%N/A0.018%
5/15/2025Tema Etfs LLC33,001$393K0.1%N/A0.047%
5/15/2025Trexquant Investment LP220,809$2.63M0.0%+116.5%0.317%
5/14/2025Walleye Capital LLC247,959$2.95M0.0%-45.2%0.356%
5/14/2025AlphaQuest LLC31,676$377K0.0%+1,028.1%0.046%
5/14/2025Wellington Management Group LLP182,246$2.17M0.0%-16.8%0.262%
5/13/2025Northwest & Ethical Investments L.P.10,030$119K0.0%+83.3%0.014%
5/13/2025Cresset Asset Management LLC21,320$254K0.0%-30.8%0.031%
5/13/2025American Century Companies Inc.31,147$371K0.0%-22.0%0.045%
5/13/2025Tejara Capital Ltd189,409$2.26M0.9%+391.5%0.272%
5/12/2025Nuveen LLC198,812$2.37M0.0%N/A0.286%
5/12/2025Invesco Ltd.78,206$931K0.0%+12.7%0.112%
5/12/2025Swiss National Bank80,100$954K0.0%-11.2%0.115%
5/9/2025Deutsche Bank AG1,552,612$18.49M0.0%+0.4%2.232%
5/9/2025Charles Schwab Investment Management Inc.133,639$1.59M0.0%+1.8%0.192%
5/9/2025Vanguard Group Inc.1,767,041$21.05M0.0%-29.1%2.540%
5/8/2025XTX Topco Ltd20,205$241K0.0%-40.0%0.029%
5/7/2025Picton Mahoney Asset Management208,029$2.48M0.0%+0.7%0.299%
5/7/2025Zurcher Kantonalbank Zurich Cantonalbank24,531$292K0.0%+25.1%0.035%
5/6/2025One Wealth Advisors LLC10,404$124K0.0%-25.6%0.015%
5/2/2025Victory Capital Management Inc.44,270$527K0.0%-14.2%0.064%
5/1/2025CWM LLC2,299$27K0.0%+1,091.2%0.003%
5/1/2025Arizona State Retirement System11,846$141K0.0%-11.7%0.017%
4/30/2025China Universal Asset Management Co. Ltd.13,816$165K0.0%-5.4%0.020%
(Data available from 1/1/2016 forward)

ZYME Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of ZYME shares?

During the previous two years, 160 institutional investors and hedge funds held shares of Zymeworks. The most heavily invested institutionals were EcoR1 Capital LLC ($288.28M), BVF Inc. IL ($63.08M), Rubric Capital Management LP ($59.12M), Redmile Group LLC ($52.09M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($46.21M), BNP PARIBAS ASSET MANAGEMENT Holding S.A. ($25.60M), and Assenagon Asset Management S.A. ($22.66M).Learn more on Zymeworks' institutional investors.

What percentage of Zymeworks' stock is owned by institutional investors?

92.89% of Zymeworks' stock is owned by institutional investors. Learn more on ZYME's institutional investor holdings.

Which institutional investors have been buying Zymeworks' stock?

Of the 130 institutional investors that purchased Zymeworks' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: EcoR1 Capital LLC ($7.94M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($2.51M), Rubric Capital Management LP ($2.23M), Assenagon Asset Management S.A. ($1.64M), Vestal Point Capital LP ($1.14M), Acadian Asset Management LLC ($778.97K), and Healthcare of Ontario Pension Plan Trust Fund ($599K).

How much institutional buying is happening at Zymeworks?

Institutional investors have bought a total of 19,825,094 shares in the last 24 months. This purchase volume represents approximately $256.36M in transactions.

Which of Zymeworks' major shareholders have been selling company stock?

Of the 72 institutional investors that sold Zymeworks' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: BNP PARIBAS ASSET MANAGEMENT Holding S.A. ($299.47M), Vanguard Group Inc. ($1.09M), Redmile Group LLC ($1.06M), Jacobs Levy Equity Management Inc. ($639.69K), Perceptive Advisors LLC ($589.40K), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($537.29K), and Vestal Point Capital LP ($430K).

How much institutional selling is happening at Zymeworks?

Institutional investors have sold a total of 307,049,217 shares in the last 24 months. This volume of shares sold represents approximately $3.86B in transactions.


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This page (NYSE:ZYME) was last updated on 10/18/2025 by MarketBeat.com Staff
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