Zymeworks (ZYME) Institutional Ownership $14.01 -0.80 (-5.40%) Closing price 04:00 PM EasternExtended Trading$13.70 -0.32 (-2.25%) As of 06:40 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Zymeworks (NYSE:ZYME)CurrentInstitutional OwnershipPercentage92.89%Number ofInstitutional Buyers(last 12 months)91TotalInstitutional Inflows(last 12 months)$242.62MNumber ofInstitutional Sellers(last 12 months)72TotalInstitutional Outflows(last 12 months)$3.86B Get ZYME Insider Trade Alerts Want to know when executives and insiders are buying or selling Zymeworks stock? 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Skip Chart & View Institutional Buying and Selling Data ZYME Institutional Buying and Selling by Quarter Zymeworks Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails8/27/2025 Squarepoint Ops LLC155,599$1.95M0.0%+144.6%0.207% 8/15/2025 Tower Research Capital LLC TRC 4,947$62K0.0%+29.6%0.007% 8/15/2025 Vestal Point Capital LP1,150,000$14.43M0.8%+130.0%1.530% 8/15/2025 Rubric Capital Management LP4,710,551$59.12M0.9%+8.6%6.267% 8/15/2025 Opaleye Management Inc.210,000$2.64M0.5%+20.0%0.279% 8/15/2025 Perceptive Advisors LLC1,275,274$16.01M1.4%-31.6%1.697% 8/15/2025 Man Group plc35,406$444K0.0%+226.1%0.047% 8/15/2025 EcoR1 Capital LLC22,970,388$288.28M17.1%+33.1%30.560% 8/15/2025 Engineers Gate Manager LP18,941$238K0.0%+52.8%0.025% 8/15/2025 BNP Paribas Financial Markets10,307$129K0.0%+157.7%0.014% Get the Latest News and Ratings for ZYME and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Zymeworks and its competitors with MarketBeat's FREE daily newsletter. 8/15/2025 Brevan Howard Capital Management LP10,628$133K0.0%N/A0.014% 8/15/2025 Bank of America Corp DE90,378$1.13M0.0%+45.5%0.120% 8/15/2025 Adage Capital Partners GP L.L.C.476,000$5.97M0.0%N/A0.633% 8/14/2025 Samsara Biocapital LLC310,300$3.89M0.8%-53.5%0.413% 8/14/2025 Jane Street Group LLC12,549$157K0.0%-90.8%0.017% 8/14/2025 California State Teachers Retirement System42,873$538K0.0%-2.1%0.057% 8/14/2025 Acuta Capital Partners LLC83,655$1.05M1.5%+22.2%0.111% 8/14/2025 Raymond James Financial Inc.124,435$1.56M0.0%+6.6%0.166% 8/14/2025 Redmile Group LLC4,150,627$52.09M5.5%-13.3%5.522% 8/14/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.26,863$337K0.0%-17.1%0.036% 8/14/2025 The Manufacturers Life Insurance Company 19,070$239K0.0%-6.8%0.025% 8/14/2025 Squarepoint Ops LLC155,599$1.95M0.0%+144.6%0.207% 8/14/2025 Qube Research & Technologies Ltd69,874$877K0.0%N/A0.093% 8/14/2025 AXA S.A.175,121$2.20M0.0%N/A0.233% 8/13/2025 Cresset Asset Management LLC16,638$209K0.0%-22.0%0.022% 8/13/2025 Tema Etfs LLC51,855$651K0.2%+57.1%0.069% 8/13/2025 Kennedy Capital Management LLC146,954$1.84M0.0%+7.8%0.196% 8/13/2025 Invesco Ltd.89,371$1.12M0.0%+14.3%0.119% 8/13/2025 Panagora Asset Management Inc.33,559$421K0.0%N/A0.045% 8/13/2025 Schroder Investment Management Group304,666$3.80M0.0%-5.4%0.405% 8/13/2025 Virtus Investment Advisers LLC7,178$90K0.0%-44.8%0.010% 8/13/2025 Tejara Capital Ltd200,150$2.51M1.2%+5.7%0.266% 8/13/2025 Norges Bank201,700$2.53M0.0%N/A0.268% 8/13/2025 Hsbc Holdings PLC36,497$461K0.0%N/A0.049% 8/13/2025 Russell Investments Group Ltd.28,312$355K0.0%+827.4%0.041% 8/12/2025 XTX Topco Ltd31,021$389K0.0%+53.5%0.045% 8/12/2025 Prudential Financial Inc.44,965$564K0.0%+5.6%0.065% 8/12/2025 Rhumbline Advisers86,083$1.08M0.0%+4.0%0.124% 8/12/2025 Legal & General Group Plc43,763$549K0.0%-6.5%0.063% 8/12/2025 Hillsdale Investment Management Inc.205,022$2.57M0.1%-13.5%0.294% Market Panic: Trump Just Dropped a Bomb on Your Stocks (Ad)tock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tariffs just lit the fuse. Millions of investors are blindsided as stocks plunge… but this is only Phase 1. If you're still holding the wrong assets, you could lose 30% or more in the coming weeks.Don't wait for the next drop to wipe you out. Get the FREE Guide Before Markets Open Tomorrow8/12/2025 JPMorgan Chase & Co.441,690$5.54M0.0%+1,050.0%0.634% 8/12/2025 Swiss National Bank73,100$917K0.0%-8.7%0.105% 8/11/2025 Universal Beteiligungs und Servicegesellschaft mbH14,300$179K0.0%N/A0.021% 8/8/2025 Intech Investment Management LLC23,163$291K0.0%-42.5%0.033% 8/8/2025 Creative Planning25,389$319K0.0%+114.8%0.036% 8/7/2025 ProShare Advisors LLC12,665$159K0.0%-15.1%0.018% 8/7/2025 Campbell & CO Investment Adviser LLC14,985$188K0.0%N/A0.022% 8/6/2025 BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,039,656$25.60M0.1%-99.3%2.927% 8/5/2025 Bank of Montreal Can27,642$347K0.0%+6.7%0.040% 8/1/2025 Teacher Retirement System of Texas10,368$130K0.0%-7.2%0.015% 8/1/2025 Envestnet Asset Management Inc.14,606$183K0.0%-70.5%0.021% 7/31/2025 AlphaQuest LLC14,026$176K0.0%-55.7%0.020% 7/29/2025 VIRGINIA RETIREMENT SYSTEMS ET Al54,075$679K0.0%N/A0.078% 7/28/2025 Ritholtz Wealth Management25,235$317K0.0%-58.3%0.036% 7/25/2025 CWM LLC8,570$108K0.0%+272.8%0.012% 7/23/2025 KLP Kapitalforvaltning AS7,300$92K0.0%-29.1%0.010% 7/21/2025 Platinum Investment Management Ltd.238,391$2.99M0.2%-14.5%0.342% 7/11/2025 Assenagon Asset Management S.A.492,780$6.18M0.0%-0.5%0.707% 6/18/2025 Voya Investment Management LLC15,653$186K0.0%-73.7%0.022% 5/29/2025 Rhumbline Advisers82,738$985K0.0%-20.3%0.119% 5/19/2025 Jane Street Group LLC135,763$1.62M0.0%+487.0%0.195% 5/19/2025 UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC3,879,945$46.21M0.0%+184.2%5.576% 5/16/2025 Empowered Funds LLC360,044$4.29M0.1%+2.1%0.517% 5/16/2025 Goldman Sachs Group Inc.200,047$2.38M0.0%-20.0%0.288% 5/16/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.32,385$386K0.0%+4.6%0.047% 5/16/2025 Jacobs Levy Equity Management Inc.12,040$143K0.0%-96.6%0.017% 5/16/2025 Granahan Investment Management LLC407,589$4.85M0.2%-0.9%0.586% 5/16/2025 EcoR1 Capital LLC17,259,548$205.56M12.2%+14.8%24.806% 5/16/2025 Bridgeway Capital Management LLC766,944$9.13M0.2%+1.0%1.102% 5/16/2025 AQR Capital Management LLC48,485$577K0.0%+86.0%0.070% 5/16/2025 ADAR1 Capital Management LLC50,000$596K0.1%N/A0.072% 5/15/2025 Redmile Group LLC4,788,945$57.04M5.4%-1.1%6.883% 5/15/2025 Vestal Point Capital LP500,000$5.96M0.4%+170.3%0.719% 5/15/2025 Royal Bank of Canada56,771$676K0.0%-6.8%0.082% 5/15/2025 Magnetar Financial LLC12,448$148K0.0%N/A0.018% 5/15/2025 Tema Etfs LLC33,001$393K0.1%N/A0.047% 5/15/2025 Trexquant Investment LP220,809$2.63M0.0%+116.5%0.317% 5/14/2025 Walleye Capital LLC247,959$2.95M0.0%-45.2%0.356% 5/14/2025 AlphaQuest LLC31,676$377K0.0%+1,028.1%0.046% 5/14/2025 Wellington Management Group LLP182,246$2.17M0.0%-16.8%0.262% 5/13/2025 Northwest & Ethical Investments L.P.10,030$119K0.0%+83.3%0.014% 5/13/2025 Cresset Asset Management LLC21,320$254K0.0%-30.8%0.031% 5/13/2025 American Century Companies Inc.31,147$371K0.0%-22.0%0.045% 5/13/2025 Tejara Capital Ltd189,409$2.26M0.9%+391.5%0.272% 5/12/2025 Nuveen LLC198,812$2.37M0.0%N/A0.286% 5/12/2025 Invesco Ltd.78,206$931K0.0%+12.7%0.112% 5/12/2025 Swiss National Bank80,100$954K0.0%-11.2%0.115% 5/9/2025 Deutsche Bank AG1,552,612$18.49M0.0%+0.4%2.232% 5/9/2025 Charles Schwab Investment Management Inc.133,639$1.59M0.0%+1.8%0.192% 5/9/2025 Vanguard Group Inc.1,767,041$21.05M0.0%-29.1%2.540% Market Panic: Trump Just Dropped a Bomb on Your Stocks (Ad)tock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tariffs just lit the fuse. Millions of investors are blindsided as stocks plunge… but this is only Phase 1. If you're still holding the wrong assets, you could lose 30% or more in the coming weeks.Don't wait for the next drop to wipe you out. Get the FREE Guide Before Markets Open Tomorrow5/8/2025 XTX Topco Ltd20,205$241K0.0%-40.0%0.029% 5/7/2025 Picton Mahoney Asset Management208,029$2.48M0.0%+0.7%0.299% 5/7/2025 Zurcher Kantonalbank Zurich Cantonalbank24,531$292K0.0%+25.1%0.035% 5/6/2025 One Wealth Advisors LLC10,404$124K0.0%-25.6%0.015% 5/2/2025 Victory Capital Management Inc.44,270$527K0.0%-14.2%0.064% 5/1/2025 CWM LLC2,299$27K0.0%+1,091.2%0.003% 5/1/2025 Arizona State Retirement System11,846$141K0.0%-11.7%0.017% 4/30/2025 China Universal Asset Management Co. Ltd.13,816$165K0.0%-5.4%0.020% 4/29/2025 Envestnet Asset Management Inc.49,512$590K0.0%-8.5%0.071% 4/28/2025 Teacher Retirement System of Texas11,168$133K0.0%-18.7%0.016% (Data available from 1/1/2016 forward) ZYME Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of ZYME shares? During the previous two years, 160 institutional investors and hedge funds held shares of Zymeworks. The most heavily invested institutionals were EcoR1 Capital LLC ($288.28M), BVF Inc. IL ($63.08M), Rubric Capital Management LP ($59.12M), Redmile Group LLC ($52.09M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($46.21M), BNP PARIBAS ASSET MANAGEMENT Holding S.A. ($25.60M), and Vanguard Group Inc. ($21.05M).Learn more on Zymeworks' institutional investors. What percentage of Zymeworks' stock is owned by institutional investors? 92.89% of Zymeworks' stock is owned by institutional investors. Learn more on ZYME's institutional investor holdings. Which institutional investors have been buying Zymeworks' stock? Of the 130 institutional investors that purchased Zymeworks' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: EcoR1 Capital LLC ($7.94M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($2.51M), Rubric Capital Management LP ($2.23M), Vestal Point Capital LP ($1.14M), Assenagon Asset Management S.A. ($808.80K), Acadian Asset Management LLC ($778.97K), and Healthcare of Ontario Pension Plan Trust Fund ($599K). How much institutional buying is happening at Zymeworks? Institutional investors have bought a total of 19,031,486 shares in the last 24 months. This purchase volume represents approximately $242.62M in transactions. Which of Zymeworks' major shareholders have been selling company stock? Of the 72 institutional investors that sold Zymeworks' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: BNP PARIBAS ASSET MANAGEMENT Holding S.A. ($299.47M), Vanguard Group Inc. ($1.09M), Redmile Group LLC ($1.06M), Jacobs Levy Equity Management Inc. ($639.69K), Perceptive Advisors LLC ($589.40K), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($537.29K), and Vestal Point Capital LP ($430K). How much institutional selling is happening at Zymeworks? Institutional investors have sold a total of 307,417,509 shares in the last 24 months. This volume of shares sold represents approximately $3.86B in transactions. 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