OTCMKTS:OPHLY Ono Pharmaceutical (OPHLY) Stock Price, News & Analysis $4.94 -0.06 (-1.23%) As of 12:42 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartSEC FilingsBuy This Stock About Ono Pharmaceutical Stock (OTCMKTS:OPHLY) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Ono Pharmaceutical alerts:Sign Up Key Stats Today's Range$4.94▼$5.0250-Day Range$4.42▼$5.0852-Week Range$3.55▼$5.75Volume6,199 shsAverage Volume32,345 shsMarket CapitalizationN/AP/E Ratio1.08Dividend Yield335.19%Price TargetN/AConsensus RatingN/A Company Overview Ono Pharmaceutical Co., Ltd. is a Japan-based pharmaceutical company engaged in the research, development, manufacturing and marketing of prescription drugs and diagnostics. Headquartered in Osaka, the company traces its origins to the early 18th century and has grown into a global specialty‐pharmaceutical firm. Its product portfolio spans oncology, immunology, allergy and inflammatory diseases, with a notable focus on novel immunotherapies. In oncology, Ono Pharmaceutical is best known for co‐developing and commercializing nivolumab (Opdivo), an anti–PD‐1 immune checkpoint inhibitor developed in partnership with Bristol‐Myers Squibb. Beyond cancer immunotherapy, the company researches small‐molecule drugs and antibody therapeutics targeting various immunological pathways. It also produces in vitro diagnostics and laboratory reagents that support disease detection and treatment monitoring. Ono Pharmaceutical operates primarily in Japan but has extended its reach globally through strategic alliances and licensing agreements. In overseas markets, the company collaborates with multinational partners to secure regulatory approvals and to manage manufacturing and distribution. Ono’s ongoing pipeline includes compounds in clinical trials for solid tumors, hematological malignancies and immune‐mediated disorders.AI Generated. May Contain Errors. Read More Receive OPHLY Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Ono Pharmaceutical and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. 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This free guide lays it all out in plain English — from A to Z, with step-by-step examples you can follow in your own account.August 10 at 1:00 AM | Profits Run (Ad)Ono Pharmaceutical Co. - Depositary receipt (OPHLY) price target increased by 28.77% to 2.56February 4, 2026 | msn.comOno Shares Replay Information for 44th Annual J.P. Morgan Healthcare Conference PresentationJanuary 15, 2026 | finance.yahoo.comOno Pharmaceutical Co., - depositary receipt (OPHLY) price target increased by 30.66% to 1.99December 22, 2025 | msn.comOno Pharmaceutical Co., - Depositary Receipt (OPHLY) Price Target Decreased by 17.63% to 1.52November 17, 2025 | msn.comPRISM BioLab Achieved Initial Milestone and Receives the Milestone Payment in Drug Discovery Collaboration with Ono Pharmaceutical Co., Ltd.November 14, 2025 | finance.yahoo.comSee More Headlines OPHLY Stock Analysis - Frequently Asked Questions How have OPHLY shares performed this year? Ono Pharmaceutical's stock was trading at $4.55 at the start of the year. Since then, OPHLY stock has increased by 9.1% and is now trading at $4.9650. How do I buy shares of Ono Pharmaceutical? Shares of OPHLY stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Industry, Sector and Symbol Stock ExchangeOTCMKTS SectorHealthcare Industry Pharmaceuticals Sub-IndustryPharmaceuticals Current SymbolOTCMKTS:OPHLY CIK940821 Webwww.ono.co.jp Phone(166) 263-5670FaxN/AEmployees3,761Year FoundedN/AProfitability EPS (Trailing Twelve Months)N/A Trailing P/E Ratio1.08 Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current RatioN/A Quick RatioN/A Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding SharesN/AFree FloatN/AMarket CapN/A OptionableNot Optionable BetaN/A 10 Best Stocks to Own - Summer 2026Enter your email address and we’ll send you MarketBeat’s list of ten stocks set to soar in Summer 2026, despite the threat of tariffs and what's happening in Iran. These ten stocks are incredibly resilient and are likely to thrive in any economic environment. 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