Avoro Capital Advisors LLC Top Holdings and 13F Report (2025) About Avoro Capital Advisors LLCInvestment ActivityAvoro Capital Advisors LLC has $5.71 billion in total holdings as of June 30, 2025.Avoro Capital Advisors LLC owns shares of 30 different stocks, but just 13 companies or ETFs make up 80% of its holdings.Approximately 5.85% of the portfolio was purchased this quarter.About 19.88% of the portfolio was sold this quarter.This quarter, Avoro Capital Advisors LLC has purchased 33 new stocks and bought additional shares in 10 stocks.Avoro Capital Advisors LLC sold shares of 17 stocks and completely divested from 4 stocks this quarter.Largest Holdings Ascendis Pharma A/S $859,548,000United Therapeutics $681,019,500argenex $647,683,500Madrigal Pharmaceuticals $567,450,000Krystal Biotech $365,643,600 Largest New Holdings this Quarter 00973Y108 - Akero Therapeutics $186,760,000 Holding Largest Purchases this Quarter Akero Therapeutics 3,500,000 shares (about $186.76M)MoonLake Immunotherapeutics 1,379,900 shares (about $65.13M)uniQure 1,450,000 shares (about $20.21M)Vera Therapeutics 598,100 shares (about $14.09M)Alkermes 450,000 shares (about $12.87M) Largest Sales this Quarter Blueprint Medicines 3,475,000 shares (about $445.43M)United Therapeutics 305,000 shares (about $87.64M)Madrigal Pharmaceuticals 147,222 shares (about $44.56M)Ascendis Pharma A/S 238,000 shares (about $41.08M)Soleno Therapeutics 475,000 shares (about $39.80M) Sector Allocation Over TimeMap of 500 Largest Holdings ofAvoro Capital Advisors LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorASNDAscendis Pharma A/S$859,548,000$41,078,800 ▼-4.6%4,980,00015.1%MedicalUTHRUnited Therapeutics$681,019,500$87,641,750 ▼-11.4%2,370,00011.9%MedicalARGXargenex$647,683,500$33,170,766 ▼-4.9%1,175,00011.3%MedicalMDGLMadrigal Pharmaceuticals$567,450,000$44,555,266 ▼-7.3%1,875,0009.9%MedicalKRYSKrystal Biotech$365,643,600$9,759,660 ▼-2.6%2,660,0006.4%MedicalKYMRKymera Therapeutics$286,084,420$4,170,020 ▲1.5%6,555,5555.0%MedicalAPLSApellis Pharmaceuticals$211,566,6630.0%12,222,2223.7%MedicalRNAAvidity Biosciences$200,220,000$16,330,000 ▼-7.5%7,050,0003.5%MedicalMLTXMoonLake Immunotherapeutics$195,880,000$65,131,280 ▲49.8%4,150,0003.4%MedicalAKROAkero Therapeutics$186,760,000$186,760,000 ▲New Holding3,500,0003.3%MedicalSLNOSoleno Therapeutics$171,749,000$39,795,500 ▼-18.8%2,050,0003.0%MedicalXENEXenon Pharmaceuticals$169,020,000$10,694,146 ▼-6.0%5,400,0003.0%MedicalARWRArrowhead Pharmaceuticals$167,480,000$8,075,554 ▼-4.6%10,600,0002.9%MedicalMRUSMerus$165,982,193$8,182,193 ▲5.2%3,155,5552.9%MedicalVERAVera Therapeutics$148,428,000$14,091,236 ▲10.5%6,300,0002.6%MedicalFOLDAmicus Therapeutics$103,140,000$14,325,000 ▼-12.2%18,000,0001.8%MedicalALKSAlkermes$82,969,000$12,874,500 ▲18.4%2,900,0001.5%MedicalOCULOcular Therapeutix$68,672,000$6,124,800 ▼-8.2%7,400,0001.2%MedicalETNB89BIO$66,285,000$3,928,000 ▲6.3%6,750,0001.2%MedicalCNTACentessa Pharmaceuticals$65,700,000$12,483,000 ▲23.5%5,000,0001.2%MedicalQUREuniQure$50,532,500$20,213,000 ▲66.7%3,625,0000.9%MedicalTSHATaysha Gene Therapies$50,127,000$3,927,002 ▲8.5%21,700,0000.9%MedicalBPMCBlueprint Medicines$48,067,500$445,425,500 ▼-90.3%375,0000.8%MedicalTOURMALINE BIO INC$40,863,324$2,087,574 ▲5.4%2,555,5550.7%CommonBCRXBioCryst Pharmaceuticals$40,320,000$37,632,000 ▼-48.3%4,500,0000.7%MedicalMNKDMannKind$21,879,000$10,846,000 ▼-33.1%5,850,0000.4%MedicalGLUEMonte Rosa Therapeutics$16,799,750$4,151,671 ▼-19.8%3,725,0000.3%MedicalSEPTERNA INC$13,080,375$1,057,000 ▼-7.5%1,237,5000.2%CommonRAREUltragenyx Pharmaceutical$11,998,800$18,180,000 ▼-60.2%330,0000.2%MedicalAADIAadi Bioscience$5,328,3820.0%2,849,4020.1%MedicalSRPTSarepta Therapeutics$0$170,707,970 ▼-100.0%00.0%MedicalITCIIntra-Cellular Therapies$0$82,450,000 ▼-100.0%00.0%MedicalPCVXVaxcyte$0$37,760,000 ▼-100.0%00.0%MedicalAUTLAutolus Therapeutics$0$15,361,495 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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