Avoro Capital Advisors LLC Top Holdings and 13F Report (2026) About Avoro Capital Advisors LLCInvestment ActivityAvoro Capital Advisors LLC has $11.14 billion in total holdings as of June 30, 2026.Avoro Capital Advisors LLC owns shares of 26 different stocks, but just 11 companies or ETFs make up 80% of its holdings.Approximately 16.74% of the portfolio was purchased this quarter.About 24.16% of the portfolio was sold this quarter.This quarter, Avoro Capital Advisors LLC has purchased 30 new stocks and bought additional shares in 9 stocks.Avoro Capital Advisors LLC sold shares of 5 stocks and completely divested from 7 stocks this quarter.Largest Holdings United Therapeutics $1,505,082,912ASCENDIS PHARMA $1,363,235,526Krystal Biotech $1,073,713,003Madrigal Pharmaceuticals $984,408,154argenex $927,770,000 Largest New Holdings this Quarter K08588103 - ASCENDIS PHARMA $1,363,235,526 Holding423494103 - HEMAB THERAPEUTICS HLDGS INC $70,710,760 Holding81728A207 - FAETH THERAPEUTICS INC $36,100,975 Holding Largest Purchases this Quarter ASCENDIS PHARMA 5,111,111 shares (about $1.36B)Cytokinetics 1,666,666 shares (about $141.98M)DEFINIUM THERAPEUTICS INC 2,188,888 shares (about $102.97M)HEMAB THERAPEUTICS HLDGS INC 1,925,150 shares (about $70.71M)Arrowhead Pharmaceuticals 655,556 shares (about $53.43M) Largest Sales this Quarter United Therapeutics 232,223 shares (about $125.83M)Celcuity 175,000 shares (about $18.31M)Revolution Medicines 47,444 shares (about $8.89M)Vera Therapeutics 165,000 shares (about $7.08M)LEXEO THERAPEUTICS INC 385,811 shares (about $1.80M) Sector Allocation Over TimeMap of 500 Largest Holdings ofAvoro Capital Advisors LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorUTHRUnited Therapeutics$1,505,082,912$125,825,388 â–¼-7.7%2,777,77713.5%HealthcareASCENDIS PHARMA$1,363,235,526$1,363,235,526 â–²New Holding5,111,11112.2%ORDINARY SHARESKRYSKrystal Biotech$1,073,713,0030.0%2,888,8889.6%HealthcareMDGLMadrigal Pharmaceuticals$984,408,154$8,135,866 â–²0.8%1,833,3338.8%HealthcareARGXargenex$927,770,0000.0%1,000,0008.3%HealthcareARWRArrowhead Pharmaceuticals$925,591,288$53,434,370 â–²6.1%11,355,5558.3%HealthcareKYMRKymera Therapeutics$857,129,2380.0%7,474,7477.7%HealthcareRVMDRevolution Medicines$430,182,160$8,885,312 â–¼-2.0%2,297,0003.9%HealthcareCYTKCytokinetics$425,949,915$141,983,277 â–²50.0%4,999,9993.8%HealthcareCELCCelcuity$355,708,000$18,308,500 â–¼-4.9%3,400,0003.2%HealthcareGPCRStructure Therapeutics$351,836,6370.0%6,555,5553.2%HealthcareXENEXenon Pharmaceuticals$348,746,6200.0%5,777,7773.1%HealthcareDEFINIUM THERAPEUTICS INC$338,165,292$102,965,292 â–²43.8%7,188,8883.0%CommonQUREuniQure$309,881,409$35,382,463 â–²12.9%6,727,7772.8%HealthcareVERAVera Therapeutics$245,612,034$7,080,150 â–¼-2.8%5,723,8882.2%HealthcareTSHATaysha Gene Therapies$162,683,327$14,906,327 â–²10.1%23,888,8881.5%HealthcareOCULOcular Therapeutix$123,142,800$2,209,500 â–²1.8%12,540,0001.1%HealthcareDAMORA THERAPEUTICS INC$98,395,8300.0%3,783,0000.9%CommonHEMAB THERAPEUTICS HLDGS INC$70,710,760$70,710,760 â–²New Holding1,925,1500.6%CommonGHRSGH Research$48,384,0000.0%1,800,0000.4%HealthcareVRDNViridian Therapeutics$45,925,000$18,370,000 â–²66.7%2,500,0000.4%HealthcareSEPTERNA INC$44,792,8750.0%1,337,5000.4%CommonAVALO THERAPEUTICS$43,119,994$17,063,194 â–²65.5%2,333,3330.4%CommonFAETH THERAPEUTICS INC$36,100,975$36,100,975 â–²New Holding1,444,0390.3%COMMONAADIAadi Bioscience$13,050,2610.0%2,849,4020.1%HealthcareLEXEO THERAPEUTICS INC$6,932,175$1,795,950 â–¼-20.6%1,489,1890.1%CommonASNDAscendis Pharma A/S$0$1,157,945,625 â–¼-100.0%00.0%HealthcareAPLSApellis Pharmaceuticals$0$491,699,991 â–¼-100.0%00.0%HealthcareCNTACentessa Pharmaceuticals$0$454,017,673 â–¼-100.0%00.0%HealthcareTERNTerns Pharmaceuticals$0$300,240,400 â–¼-100.0%00.0%HealthcareSLNOSoleno Therapeutics$0$77,004,000 â–¼-100.0%00.0%HealthcareALKSAlkermes$0$42,432,000 â–¼-100.0%00.0%HealthcareMNKDMannKind$0$5,390,000 â–¼-100.0%00.0%HealthcareShowing largest 100 holdings. 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