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First Light Asset Management, LLC Top Holdings and 13F Report (2026)

About First Light Asset Management, LLC

Investment Activity

  • First Light Asset Management, LLC has $1.12 billion in total holdings as of March 31, 2026.
  • First Light Asset Management, LLC owns shares of 35 different stocks, but just 19 companies or ETFs make up 80% of its holdings.
  • Approximately 17.86% of the portfolio was purchased this quarter.
  • About 24.27% of the portfolio was sold this quarter.
  • This quarter, First Light Asset Management, LLC has purchased 33 new stocks and bought additional shares in 9 stocks.
  • First Light Asset Management, LLC sold shares of 19 stocks and completely divested from 5 stocks this quarter.

Largest Holdings

AxoGen
$132,611,704
PALVELLA THERAPEUTICS INC
$122,251,485
NeoGenomics
$72,196,437
SiBone
$67,610,790

Largest New Holdings this Quarter

89680M101 - TRISALUS LIFE SCIENCES INC
$20,267,308 Holding
878972108 - TECTONIC THERAPEUTICS INC
$20,021,736 Holding
68213N109 - Omnicell
$16,351,059 Holding
81663L200 - GeneDx
$15,600,772 Holding
85220G109 - SPYGLASS PHARMA INC
$9,716,250 Holding

Largest Purchases this Quarter

PALVELLA THERAPEUTICS INC
271,617 shares (about $33.86M)
APOGEE THERAPEUTICS INC
291,693 shares (about $24.55M)
TRISALUS LIFE SCIENCES INC
5,066,827 shares (about $20.27M)
TECTONIC THERAPEUTICS INC
647,743 shares (about $20.02M)
Omnicell
489,846 shares (about $16.35M)

Largest Sales this Quarter

AxoGen
1,230,558 shares (about $40.77M)
Centessa Pharmaceuticals
717,949 shares (about $28.52M)
Vera Therapeutics
555,770 shares (about $22.36M)
Rhythm Pharmaceuticals
208,663 shares (about $18.15M)
Edgewise Therapeutics
571,855 shares (about $18.01M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofFirst Light Asset Management, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
AxoGen, Inc. stock logo
AXGN
AxoGen
$132,611,704$40,768,387 â–¼-23.5%4,002,76811.9%Medical
PALVELLA THERAPEUTICS INC
$122,251,485$33,857,059 â–²38.3%980,75811.0%Common Stocks
NeoGenomics, Inc. stock logo
NEO
NeoGenomics
$72,196,437$2,263,731 â–¼-3.0%9,729,9786.5%Medical
SiBone stock logo
SIBN
SiBone
$67,610,790$4,045,212 â–²6.4%5,353,1906.1%Medical
Centessa Pharmaceuticals PLC Sponsored ADR stock logo
CNTA
Centessa Pharmaceuticals
$62,002,563$28,516,935 â–¼-31.5%1,560,9915.6%Medical
APOGEE THERAPEUTICS INC
$48,539,492$24,551,800 â–²102.4%576,6844.3%Common Stocks
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$44,349,966$2,292,027 â–¼-4.9%3,190,6454.0%Medical
Twist Bioscience Corporation stock logo
TWST
Twist Bioscience
$41,762,857$12,446,581 â–¼-23.0%878,8483.7%Medical
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$39,576,814$3,798,818 â–¼-8.8%1,089,6703.5%Medical
908 Devices Inc. stock logo
MASS
908 Devices
$37,164,086$7,566,627 â–²25.6%6,072,5633.3%Medical
NeuroPace, Inc. stock logo
NPCE
NeuroPace
$32,348,553$14,602,865 â–²82.3%2,459,9662.9%Medical
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$31,558,149$18,013,433 â–¼-36.3%1,001,8462.8%Medical
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
$31,358,803$4,481,556 â–¼-12.5%565,4312.8%Medical
Simulations Plus, Inc. stock logo
SLP
Simulations Plus
$31,119,968$7,847,369 â–²33.7%2,632,8232.8%Computer and Technology
Guardant Health, Inc. stock logo
GH
Guardant Health
$25,891,219$1,334,931 â–¼-4.9%280,2992.3%Medical
Tandem Diabetes Care, Inc. stock logo
TNDM
Tandem Diabetes Care
$25,203,087$4,317,506 â–²20.7%1,314,7152.3%Medical
AtriCure, Inc. stock logo
ATRC
AtriCure
$20,813,234$12,722,212 â–¼-37.9%729,5211.9%Medical
TRISALUS LIFE SCIENCES INC
$20,267,308$20,267,308 â–²New Holding5,066,8271.8%Common Stocks
TECTONIC THERAPEUTICS INC
$20,021,736$20,021,736 â–²New Holding647,7431.8%Common Stocks
iRhythm Technologies stock logo
IRTC
iRhythm Technologies
$19,841,050$1,681,195 â–²9.3%168,1161.8%Medical
SEPTERNA INC
$17,610,626$2,692,538 â–²18.0%732,8601.6%Common Stocks
Establishment Labs Holdings Inc. stock logo
ESTA
Establishment Labs
$17,473,364$3,710,232 â–¼-17.5%307,7381.6%Medical
Health Catalyst, Inc. stock logo
HCAT
Health Catalyst
$16,355,949$40,946 â–¼-0.2%12,878,7001.5%Medical
Omnicell, Inc. stock logo
OMCL
Omnicell
$16,351,059$16,351,059 â–²New Holding489,8461.5%Medical
KORU Medical Systems, Inc. stock logo
KRMD
KORU Medical Systems
$16,279,402$1,910,010 â–¼-10.5%3,768,3801.5%Medical
GeneDx Holdings Corp. stock logo
WGS
GeneDx
$15,600,772$15,600,772 â–²New Holding242,9271.4%Medical
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
$13,368,768$71,652 â–¼-0.5%1,843,9681.2%Medical
Vera Therapeutics, Inc. stock logo
VERA
Vera Therapeutics
$12,628,438$22,358,626 â–¼-63.9%313,9061.1%Medical
MiMedx Group, Inc stock logo
MDXG
MiMedx Group
$11,229,423$775,974 â–¼-6.5%2,842,8921.0%Medical
Butterfly Network, Inc. stock logo
BFLY
Butterfly Network
$10,747,075$613,935 â–¼-5.4%2,660,1671.0%Medical
SPYGLASS PHARMA INC
$9,716,250$9,716,250 â–²New Holding375,0000.9%Common Stocks
Organogenesis stock logo
ORGO
Organogenesis
$8,291,523$863,360 â–¼-9.4%3,498,5330.7%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$8,239,068$8,239,068 â–²New Holding141,7840.7%Medical
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$7,913,186$7,913,186 â–²New Holding201,8670.7%Medical
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$7,582,132$18,147,422 â–¼-70.5%87,1810.7%Medical
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$0$41,544,691 â–¼-100.0%00.0%Medical
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$0$38,918,365 â–¼-100.0%00.0%Medical
ABIVAX SA-ADR
$0$11,958,132 â–¼-100.0%00.0%Common Stocks
DYNE THERAPEUTICS INC
$0$3,036,318 â–¼-100.0%00.0%Common Stocks
iShares Russell 2000 Growth ETF stock logo
IWO
iShares Russell 2000 Growth ETF
$0$245,488 â–¼-100.0%00.0%ETF

Showing largest 100 holdings. View all holdings.
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