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Great Point Partners LLC Top Holdings and 13F Report (2025)

About Great Point Partners LLC

Investment Activity

  • Great Point Partners LLC has $188.80 million in total holdings as of March 31, 2025.
  • Great Point Partners LLC owns shares of 32 different stocks, but just 19 companies or ETFs make up 80% of its holdings.
  • Approximately 30.78% of the portfolio was purchased this quarter.
  • About 20.51% of the portfolio was sold this quarter.
  • This quarter, Great Point Partners LLC has purchased 26 new stocks and bought additional shares in 6 stocks.
  • Great Point Partners LLC sold shares of 8 stocks and completely divested from 4 stocks this quarter.

Largest Holdings

Cytokinetics
$14,870,300
Evolus
$11,365,258
ABIVAX SA
$10,238,194

Largest New Holdings this Quarter

00972D105 - Akebia Therapeutics
$9,549,773 Holding
04351P101 - Ascendis Pharma A/S
$7,793,000 Holding
03237H101 - Amylyx Pharmaceuticals
$6,414,466 Holding
45258J102 - Immunovant
$6,408,750 Holding
86627T108 - Summit Therapeutics
$4,822,500 Holding

Largest Purchases this Quarter

Akebia Therapeutics
4,973,840 shares (about $9.55M)
Ascendis Pharma A/S
50,000 shares (about $7.79M)
Amylyx Pharmaceuticals
1,811,996 shares (about $6.41M)
Immunovant
375,000 shares (about $6.41M)
Summit Therapeutics
250,000 shares (about $4.82M)

Largest Sales this Quarter

KalVista Pharmaceuticals
772,636 shares (about $8.92M)
Ionis Pharmaceuticals
255,007 shares (about $7.69M)
Dynavax Technologies
264,121 shares (about $3.43M)
HELIX ACQUISITION CORP II
126,167 shares (about $1.43M)
Voyager Therapeutics
200,476 shares (about $677.61K)

Sector Allocation Over Time

Map of 500 Largest Holdings ofGreat Point Partners LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$14,870,300$401,900 2.8%370,0007.9%Medical
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$11,705,795$8,916,219 -43.2%1,014,3676.2%Medical
Evolus, Inc. stock logo
EOLS
Evolus
$11,365,258$592,105 5.5%944,7436.0%Medical
ABIVAX SA
$10,238,194$65,075 -0.6%1,638,1115.4%SPONSORED ADS
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$10,110,0000.0%750,0005.4%Medical
Merus stock logo
MRUS
Merus
$9,981,896$3,327,804 50.0%237,1565.3%Medical
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
$9,549,773$9,549,773 New Holding4,973,8405.1%Medical
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$8,228,8760.0%245,2724.4%Medical
Ascendis Pharma A/S stock logo
ASND
Ascendis Pharma A/S
$7,793,000$7,793,000 New Holding50,0004.1%Medical
Dynavax Technologies Co. stock logo
DVAX
Dynavax Technologies
$7,728,551$3,425,650 -30.7%595,8794.1%Medical
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
$7,542,500$7,693,561 -50.5%250,0004.0%Medical
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$6,414,466$6,414,466 New Holding1,811,9963.4%Medical
Immunovant, Inc. stock logo
IMVT
Immunovant
$6,408,750$6,408,750 New Holding375,0003.4%Medical
Unicycive Therapeutics, Inc. stock logo
UNCY
Unicycive Therapeutics
$6,312,4020.0%10,980,0003.3%Medical
NEUROGENE INC
$5,514,988$330,257 6.4%470,9642.9%COM
DIANTHUS THERAPEUTICS INC
$4,988,5000.0%275,0002.6%COM
Summit Therapeutics Inc. stock logo
SMMT
Summit Therapeutics
$4,822,500$4,822,500 New Holding250,0002.6%Medical
Legend Biotech Co. stock logo
LEGN
Legend Biotech
$4,690,483$4,690,483 New Holding138,2402.5%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$4,361,922$4,361,922 New Holding115,5172.3%Medical
Autolus Therapeutics plc stock logo
AUTL
Autolus Therapeutics
$4,229,811$434,747 -9.3%2,728,9102.2%Medical
HELIX ACQUISITION CORP II
$4,224,313$1,425,687 -25.2%373,8332.2%CL A ORD SHS
Zura Bio Limited stock logo
ZURA
Zura Bio
$4,089,5500.0%3,170,1942.2%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$3,428,726$3,428,726 New Holding175,5621.8%Medical
Arcellx, Inc. stock logo
ACLX
Arcellx
$2,952,000$2,952,000 New Holding45,0001.6%Medical
Mereo BioPharma Group plc stock logo
MREO
Mereo BioPharma Group
$2,868,750$281,250 10.9%1,275,0001.5%Medical
Context Therapeutics Inc. stock logo
CNTX
Context Therapeutics
$2,866,4310.0%4,683,7111.5%Medical
Rezolute, Inc. stock logo
RZLT
Rezolute
$2,415,822$612,329 34.0%833,0421.3%Medical
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$2,152,715$2,152,715 New Holding149,7021.1%Medical
Voyager Therapeutics, Inc. stock logo
VYGR
Voyager Therapeutics
$2,116,810$677,609 -24.2%626,2751.1%Medical
ProMIS Neurosciences, Inc. stock logo
PMN
ProMIS Neurosciences
$1,839,6870.0%2,645,1281.0%Medical
UPSTREAM BIO INC
$1,836,0000.0%300,0001.0%COM
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$1,147,500$276,750 -19.4%850,0000.6%Medical
JASPER THERAPEUTICS INC
$0$6,892,484 -100.0%00.0%COM NEW
ORUKA THERAPEUTICS INC
$0$4,436,490 -100.0%00.0%COM
OPTINOSE INC
$0$2,473,397 -100.0%00.0%COM NEW
UroGen Pharma Ltd. stock logo
URGN
UroGen Pharma
$0$2,000,528 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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