NASDAQ:PLRX Pliant Therapeutics (PLRX) Stock Price, News & Analysis $1.11 -0.02 (-1.77%) Closing price 09/18/2026 04:00 PM EasternExtended Trading$1.12 +0.00 (+0.45%) As of 09/18/2026 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC Filings About Pliant Therapeutics Stock (NASDAQ:PLRX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Pliant Therapeutics alerts:Sign Up Key Stats Today's Range$1.09▼$1.1350-Day Range$1.03▼$1.1952-Week Range$1.02▼$1.95Volume438,690 shsAverage Volume374,925 shsMarket Capitalization$68.73 millionP/E RatioN/ADividend YieldN/APrice Target$3.00Consensus RatingReduce Company Overview Pliant Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing therapies for fibrotic diseases. The company’s research centers on integrins, cell-surface proteins that regulate biological processes involved in tissue repair and fibrosis. Pliant seeks to develop medicines that address fibrosis in organs including the lungs and liver. Pliant’s lead investigational product is bexotegrast, an oral small-molecule inhibitor designed to selectively target the alphaV beta6 and alphaV beta1 integrins. The therapy has been evaluated in clinical studies for idiopathic pulmonary fibrosis and is also being investigated for liver-related fibrotic diseases, including primary sclerosing cholangitis. As an investigational medicine, bexotegrast has not been approved for commercial use. Founded in 2015 and headquartered in South San Francisco, California, Pliant conducts research and clinical development primarily in the United States while working with clinical and research partners in other regions as its programs advance. The company is led by Chief Executive Officer Bernard Coulie, M.D., Ph.D., and its shares trade on the Nasdaq under the symbol PLRX.AI Generated. May Contain Errors. Read More Pliant Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks33rd Percentile Overall ScorePLRX MarketRank™: Pliant Therapeutics scored higher than 33% of companies evaluated by MarketBeat, and ranked 723rd out of 897 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.1 / 5Analyst RatingReduce Consensus RatingPliant Therapeutics has received a consensus rating of Reduce. The company's average rating score is 1.75, and is based on no strong buy ratings, 1 buy rating, 1 hold rating, and 2 sell ratings.Upside PotentialPliant Therapeutics has a consensus price target of $3.00, representing about 170.3% upside from its current price of $1.11.Amount of Analyst CoveragePliant Therapeutics has only been the subject of 1 research reports in the past 90 days.Read more about Pliant Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Pliant Therapeutics are expected to decrease in the coming year, from ($1.42) to ($1.53) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Pliant Therapeutics is -0.74, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Pliant Therapeutics is -0.74, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioPliant Therapeutics has a P/B Ratio of 0.38. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Pliant Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted5.80% of the float of Pliant Therapeutics has been sold short.Short Interest Ratio / Days to CoverPliant Therapeutics has a short interest ratio ("days to cover") of 7.19.Change versus previous monthShort interest in Pliant Therapeutics has recently increased by 18.41%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldPliant Therapeutics does not currently pay a dividend.Dividend GrowthPliant Therapeutics does not have a long track record of dividend growth. News and Social Media2.0 / 5News Sentiment0.26 News SentimentPliant Therapeutics has a news sentiment score of 0.26. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.56 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Pliant Therapeutics this week, compared to 1 article on an average week.MarketBeat FollowsOnly 1 people have added Pliant Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership1.0 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Pliant Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders8.74% of the stock of Pliant Therapeutics is held by insiders.Percentage Held by Institutions97.30% of the stock of Pliant Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Pliant Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. PLRX Stock News HeadlinesPliant Therapeutics, Inc. (NASDAQ:PLRX) Receives $3.00 Average Target Price from AnalystsSeptember 17 at 3:31 AM | americanbankingnews.comPliant Therapeutics consensus price target lowered 20% to $2.04September 16, 2026 | msn.comA new kind of civil war is coming after election day?Across America, AI-driven backlash is fueling protests, lawsuits, and moratoria that could reshape the political and investment landscape. Whitney Tilson believes tensions may come to a head at midnight on November 4th, the day after the midterm elections, with major implications for your portfolio. | Stansberry Research (Ad)Pliant Therapeutics Inc Ordinary Shares PLRXAugust 28, 2026 | morningstar.comMPliant Therapeutics Receives FDA Fast Track Designation for PLN-101095 in Combination with Pembrolizumab for the Treatment of ICI-Refractory Solid TumorsAugust 18, 2026 | globenewswire.comOppenheimer Sticks to Their Hold Rating for Pliant Therapeutics (PLRX)August 14, 2026 | theglobeandmail.comPliant Therapeutics, Inc.: Pliant Therapeutics Provides Corporate Update and Reports Second Quarter 2026 Financial ResultsAugust 12, 2026 | finanznachrichten.dePliant Therapeutics Provides Corporate Update and Reports Second Quarter 2026 Financial ResultsAugust 11, 2026 | globenewswire.comSee More Headlines PLRX Stock Analysis - Frequently Asked Questions How have PLRX shares performed this year? Pliant Therapeutics' stock was trading at $1.22 on January 1st, 2026. Since then, PLRX shares have decreased by 9.0% and is now trading at $1.11. How were Pliant Therapeutics' earnings last quarter? Pliant Therapeutics, Inc. (NASDAQ:PLRX) issued its quarterly earnings data on Tuesday, August, 11th. The company reported ($0.36) earnings per share (EPS) for the quarter, missing the consensus estimate of ($0.34) by $0.02. When did Pliant Therapeutics IPO? Pliant Therapeutics (PLRX) raised $135 million in an IPO on Wednesday, June 3rd 2020. The company issued 9,000,000 shares at $14.00-$16.00 per share. Citigroup, Cowen and Piper Sandler acted as the underwriters for the IPO and Needham & Company was co-manager. Who are Pliant Therapeutics' major shareholders? Top institutional investors of Pliant Therapeutics include ADAR1 Capital Management LLC (8.90%), Monaco Asset Management SAM (3.13%), BlackRock Inc. (1.86%) and Connor Clark & Lunn Investment Management Ltd. (0.87%). Insiders that own company stock include Bernard Coulie, Keith Lamont Cummings, Eric Lefebvre, Hans Hull, Mike Ouimette and Minnie Kuo. View institutional ownership trends. How do I buy shares of Pliant Therapeutics? Shares of PLRX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Pliant Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Pliant Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Broadcom (AVGO), Advanced Micro Devices (AMD), Adobe (ADBE), ServiceNow (NOW) and CrowdStrike (CRWD). Company Calendar Last Earnings8/11/2026Today9/20/2026Next Earnings (Estimated)11/05/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (5m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 PLRX's financial health is in the Yellow zone, according to TradeSmith. PLRX has been in this zone for over 5 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:PLRX CIK1746473 Webpliantrx.com Phone650-481-6770FaxN/AEmployees49Year Founded2016Price Target and Rating Average Price Target for Pliant Therapeutics$3.00 High Price Target$3.00 Low Price Target$3.00 Potential Upside/Downside+170.3%Consensus RatingReduce Rating Score (0-4)1.75 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($1.49) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$149.34 million Net MarginsN/A Pretax MarginN/A Return on Equity-52.17% Return on Assets-40.46% Debt Debt-to-Equity RatioN/A Current Ratio9.90 Quick Ratio9.90 Sales & Book Value Annual Sales$1.58 million Price / Sales43.50 Cash FlowN/A Price / Cash FlowN/A Book Value$2.95 per share Price / Book0.38Miscellaneous Outstanding Shares61,920,000Free Float56,510,000Market Cap$68.73 million OptionableOptionable Beta1.27 Social Links 7 Stocks That Will Be Magnificent in 2026Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2026. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free Report This page (NASDAQ:PLRX) was last updated on 9/20/2026 by MarketBeat.com Staff. From Our Partners“Elon’s nightmare” could fund your retirementMarc Chaikin, the 60 year Wall Street veteran whose Chaikin Money Flow indicator sits on every Bloomberg termi...Chaikin Analytics | SponsoredYou’ve never seen anything like this beforeFor centuries, families like the Rothschilds, Morgans, and Rockefellers have quietly used one overlooked type ...Porter & Company | SponsoredMy top 3 AI picks for the next decadeAlexander Green bought Apple in 1996, recommended Nvidia at a split-adjusted 66 cents in 2004, and picked up A...The Oxford Club | SponsoredYour $29.97 book is free todayWhy Some Traders Skip Stocks Entirely You don't need a big account to trade options. 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