Does the media prefer PLRX or CLLS?

In the previous week, Cellectis had 1 more articles in the media than Pliant Therapeutics. MarketBeat recorded 2 mentions for Cellectis and 1 mentions for Pliant Therapeutics. Cellectis' average media sentiment score of 0.50 beat Pliant Therapeutics' score of 0.00 indicating that Cellectis is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Pliant Therapeutics 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Cellectis 0 Very Positive mention(s) 2 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive

Is NMRA or PLRX more profitable?

Pliant Therapeutics' return on equity of -58.11% beat Neumora Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets Neumora Therapeutics N/A -181.70% -119.15% Pliant Therapeutics N/A -58.11% -44.37%

Pliant Therapeutics (PLRX) Competitors

$1.17 0.00 (0.00%)

Closing price 07/2/2026 04:00 PM Eastern

Extended Trading

$1.17 +0.00 (+0.09%)

As of 07/2/2026 06:56 PM Eastern

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PLRX vs. CLLS, NMRA, BCYC, LYEL, and TRDA

Should you buy Pliant Therapeutics stock or one of its competitors? MarketBeat compares Pliant Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Pliant Therapeutics include Cellectis (CLLS), Neumora Therapeutics (NMRA), Bicycle Therapeutics (BCYC), Lyell Immunopharma (LYEL), and Entrada Therapeutics (TRDA). These companies are all part of the "pharmaceutical products" industry.

How does Pliant Therapeutics compare to Cellectis?

Pliant Therapeutics (NASDAQ:PLRX) and Cellectis (NASDAQ:CLLS) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, media sentiment, profitability, analyst recommendations, institutional ownership, dividends, valuation and risk.

Pliant Therapeutics has a beta of 1.21, indicating that its share price is 21% more volatile than the broader market. Comparatively, Cellectis has a beta of 2.88, indicating that its share price is 188% more volatile than the broader market.

97.3% of Pliant Therapeutics shares are owned by institutional investors. Comparatively, 63.9% of Cellectis shares are owned by institutional investors. 8.0% of Pliant Therapeutics shares are owned by insiders. Comparatively, 16.4% of Cellectis shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Pliant Therapeutics currently has a consensus price target of $3.00, indicating a potential upside of 156.41%. Cellectis has a consensus price target of $7.00, indicating a potential upside of 112.12%. Given Pliant Therapeutics' higher possible upside, equities research analysts clearly believe Pliant Therapeutics is more favorable than Cellectis.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Pliant Therapeutics	2 Sell rating(s)	2 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.80
Cellectis	1 Sell rating(s)	0 Hold rating(s)	4 Buy rating(s)	1 Strong Buy rating(s)	2.83

Pliant Therapeutics has a net margin of 0.00% compared to Cellectis' net margin of -89.51%. Pliant Therapeutics' return on equity of -58.11% beat Cellectis' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Pliant Therapeutics	N/A	-58.11%	-44.37%
Cellectis	-89.51%	-80.66%	-20.51%

Cellectis has higher revenue and earnings than Pliant Therapeutics. Cellectis is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Pliant Therapeutics	$1.58M	45.85	-$149.34M	-$1.84	N/A
Cellectis	$68.07M	4.86	-$67.59M	-$0.67	N/A

In the previous week, Cellectis had 1 more articles in the media than Pliant Therapeutics. MarketBeat recorded 2 mentions for Cellectis and 1 mentions for Pliant Therapeutics. Cellectis' average media sentiment score of 0.50 beat Pliant Therapeutics' score of 0.00 indicating that Cellectis is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Pliant Therapeutics	0 Very Positive mention(s)	0 Positive mention(s)	1 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Neutral
Cellectis	0 Very Positive mention(s)	2 Positive mention(s)	0 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Summary

Cellectis beats Pliant Therapeutics on 11 of the 17 factors compared between the two stocks.

How does Pliant Therapeutics compare to Neumora Therapeutics?

Neumora Therapeutics (NASDAQ:NMRA) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their risk, analyst recommendations, dividends, valuation, profitability, earnings, institutional ownership and media sentiment.

Pliant Therapeutics' return on equity of -58.11% beat Neumora Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Neumora Therapeutics	N/A	-181.70%	-119.15%
Pliant Therapeutics	N/A	-58.11%	-44.37%

Neumora Therapeutics currently has a consensus price target of $6.86, indicating a potential upside of 310.61%. Pliant Therapeutics has a consensus price target of $3.00, indicating a potential upside of 156.41%. Given Neumora Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Neumora Therapeutics is more favorable than Pliant Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Neumora Therapeutics	2 Sell rating(s)	1 Hold rating(s)	6 Buy rating(s)	1 Strong Buy rating(s)	2.60
Pliant Therapeutics	2 Sell rating(s)	2 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.80

Neumora Therapeutics has a beta of 2.74, suggesting that its stock price is 174% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, suggesting that its stock price is 21% more volatile than the broader market.

In the previous week, Pliant Therapeutics had 1 more articles in the media than Neumora Therapeutics. MarketBeat recorded 1 mentions for Pliant Therapeutics and 0 mentions for Neumora Therapeutics. Neumora Therapeutics' average media sentiment score of 0.00 equaled Pliant Therapeutics'average media sentiment score.

Company	Overall Sentiment
Neumora Therapeutics	Neutral
Pliant Therapeutics	Neutral

47.7% of Neumora Therapeutics shares are owned by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are owned by institutional investors. 26.9% of Neumora Therapeutics shares are owned by insiders. Comparatively, 8.0% of Pliant Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Pliant Therapeutics has higher revenue and earnings than Neumora Therapeutics. Neumora Therapeutics is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Neumora Therapeutics	N/A	N/A	-$236.93M	-$1.33	N/A
Pliant Therapeutics	$1.58M	45.85	-$149.34M	-$1.84	N/A

Summary

Neumora Therapeutics and Pliant Therapeutics tied by winning 7 of the 14 factors compared between the two stocks.

How does Pliant Therapeutics compare to Bicycle Therapeutics?

Bicycle Therapeutics (NASDAQ:BCYC) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their valuation, earnings, dividends, risk, media sentiment, profitability, analyst recommendations and institutional ownership.

Pliant Therapeutics has lower revenue, but higher earnings than Bicycle Therapeutics. Bicycle Therapeutics is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Bicycle Therapeutics	$63.50M	4.78	-$218.96M	-$3.15	N/A
Pliant Therapeutics	$1.58M	45.85	-$149.34M	-$1.84	N/A

86.2% of Bicycle Therapeutics shares are owned by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are owned by institutional investors. 22.9% of Bicycle Therapeutics shares are owned by insiders. Comparatively, 8.0% of Pliant Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Pliant Therapeutics has a net margin of 0.00% compared to Bicycle Therapeutics' net margin of -344.95%. Bicycle Therapeutics' return on equity of -35.74% beat Pliant Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Bicycle Therapeutics	-344.95%	-35.74%	-29.54%
Pliant Therapeutics	N/A	-58.11%	-44.37%

In the previous week, Pliant Therapeutics had 1 more articles in the media than Bicycle Therapeutics. MarketBeat recorded 1 mentions for Pliant Therapeutics and 0 mentions for Bicycle Therapeutics. Bicycle Therapeutics' average media sentiment score of 0.00 equaled Pliant Therapeutics'average media sentiment score.

Company	Overall Sentiment
Bicycle Therapeutics	Neutral
Pliant Therapeutics	Neutral

Bicycle Therapeutics has a beta of 1.55, suggesting that its stock price is 55% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, suggesting that its stock price is 21% more volatile than the broader market.

Bicycle Therapeutics presently has a consensus price target of $14.00, suggesting a potential upside of 221.84%. Pliant Therapeutics has a consensus price target of $3.00, suggesting a potential upside of 156.41%. Given Bicycle Therapeutics' stronger consensus rating and higher probable upside, equities research analysts plainly believe Bicycle Therapeutics is more favorable than Pliant Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Bicycle Therapeutics	1 Sell rating(s)	3 Hold rating(s)	5 Buy rating(s)	0 Strong Buy rating(s)	2.44
Pliant Therapeutics	2 Sell rating(s)	2 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.80

Summary

Bicycle Therapeutics beats Pliant Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Pliant Therapeutics compare to Lyell Immunopharma?

Pliant Therapeutics (NASDAQ:PLRX) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their media sentiment, valuation, earnings, analyst recommendations, institutional ownership, dividends, profitability and risk.

Pliant Therapeutics has higher revenue and earnings than Lyell Immunopharma. Lyell Immunopharma is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Pliant Therapeutics	$1.58M	45.85	-$149.34M	-$1.84	N/A
Lyell Immunopharma	$40K	8,194.66	-$274.45M	-$13.80	N/A

Pliant Therapeutics presently has a consensus price target of $3.00, indicating a potential upside of 156.41%. Lyell Immunopharma has a consensus price target of $43.00, indicating a potential upside of 206.05%. Given Lyell Immunopharma's stronger consensus rating and higher probable upside, analysts clearly believe Lyell Immunopharma is more favorable than Pliant Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Pliant Therapeutics	2 Sell rating(s)	2 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.80
Lyell Immunopharma	1 Sell rating(s)	1 Hold rating(s)	4 Buy rating(s)	1 Strong Buy rating(s)	2.71

97.3% of Pliant Therapeutics shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 8.0% of Pliant Therapeutics shares are owned by insiders. Comparatively, 6.2% of Lyell Immunopharma shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Pliant Therapeutics has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -794,858.12%. Pliant Therapeutics' return on equity of -58.11% beat Lyell Immunopharma's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Pliant Therapeutics	N/A	-58.11%	-44.37%
Lyell Immunopharma	-794,858.12%	-85.71%	-66.41%

In the previous week, Pliant Therapeutics had 1 more articles in the media than Lyell Immunopharma. MarketBeat recorded 1 mentions for Pliant Therapeutics and 0 mentions for Lyell Immunopharma. Lyell Immunopharma's average media sentiment score of 1.00 beat Pliant Therapeutics' score of 0.00 indicating that Lyell Immunopharma is being referred to more favorably in the news media.

Company	Overall Sentiment
Pliant Therapeutics	Neutral
Lyell Immunopharma	Positive

Pliant Therapeutics has a beta of 1.21, suggesting that its share price is 21% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.06, suggesting that its share price is 106% less volatile than the broader market.

Summary

Pliant Therapeutics beats Lyell Immunopharma on 11 of the 17 factors compared between the two stocks.

How does Pliant Therapeutics compare to Entrada Therapeutics?

Entrada Therapeutics (NASDAQ:TRDA) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their valuation, institutional ownership, profitability, analyst recommendations, earnings, dividends, risk and media sentiment.

In the previous week, Pliant Therapeutics had 1 more articles in the media than Entrada Therapeutics. MarketBeat recorded 1 mentions for Pliant Therapeutics and 0 mentions for Entrada Therapeutics. Entrada Therapeutics' average media sentiment score of 0.00 equaled Pliant Therapeutics'average media sentiment score.

Company	Overall Sentiment
Entrada Therapeutics	Neutral
Pliant Therapeutics	Neutral

Entrada Therapeutics has a beta of -0.26, suggesting that its stock price is 126% less volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, suggesting that its stock price is 21% more volatile than the broader market.

86.4% of Entrada Therapeutics shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 9.5% of Entrada Therapeutics shares are held by insiders. Comparatively, 8.0% of Pliant Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Entrada Therapeutics presently has a consensus price target of $17.50, suggesting a potential upside of 126.68%. Pliant Therapeutics has a consensus price target of $3.00, suggesting a potential upside of 156.41%. Given Pliant Therapeutics' higher probable upside, analysts plainly believe Pliant Therapeutics is more favorable than Entrada Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Entrada Therapeutics	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.33
Pliant Therapeutics	2 Sell rating(s)	2 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.80

Entrada Therapeutics has higher revenue and earnings than Pliant Therapeutics. Entrada Therapeutics is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Entrada Therapeutics	$25.42M	11.79	-$143.75M	-$3.99	N/A
Pliant Therapeutics	$1.58M	45.85	-$149.34M	-$1.84	N/A

Pliant Therapeutics has a net margin of 0.00% compared to Entrada Therapeutics' net margin of -2,895.05%. Entrada Therapeutics' return on equity of -51.22% beat Pliant Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Entrada Therapeutics	-2,895.05%	-51.22%	-42.20%
Pliant Therapeutics	N/A	-58.11%	-44.37%

Summary

Pliant Therapeutics beats Entrada Therapeutics on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PLRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

PLRX vs. The Competition

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Metric	Pliant Therapeutics	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$72.45M	$3.78B	$7.16B	$12.48B
Dividend Yield	N/A	2.16%	2.66%	6.52%
P/E Ratio	-0.64	21.61	28.02	24.70
Price / Sales	45.85	340.22	540.55	99.42
Price / Cash	N/A	147.12	49.26	57.09
Price / Book	0.40	8.66	10.96	6.46
Net Income	-$149.34M	$23.81M	$3.57B	$337.01M
7 Day Performance	2.63%	3.39%	2.12%	1.69%
1 Month Performance	1.74%	10.81%	5.25%	3.81%
1 Year Performance	-6.02%	62.61%	33.29%	23.90%

Pliant Therapeutics Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
PLRX Pliant Therapeutics	2.0239 of 5 stars	$1.17 flat	$3.00 +156.4%	-6.0%	$72.45M	$1.58M	N/A	90	Gap Down High Trading Volume
CLLS Cellectis	2.4494 of 5 stars	$2.86 -4.0%	$7.00 +144.8%	+108.2%	$286.97M	$68.07M	N/A	290	Gap Down
NMRA Neumora Therapeutics	3.7478 of 5 stars	$1.54 +0.3%	$6.86 +346.7%	+105.9%	$284.41M	N/A	N/A	108	Gap Down
BCYC Bicycle Therapeutics	3.0528 of 5 stars	$4.06 +1.9%	$14.00 +245.3%	-41.4%	$282.74M	$63.50M	N/A	240
LYEL Lyell Immunopharma	3.7512 of 5 stars	$11.98 -6.0%	$43.00 +259.1%	+49.2%	$279.38M	$40K	N/A	270	Positive News Gap Down

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This page (NASDAQ:PLRX) was last updated on 7/5/2026 by MarketBeat.com Staff.

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Pliant Therapeutics (PLRX) Competitors

PLRX vs. CLLS, NMRA, BCYC, LYEL, and TRDA

How does Pliant Therapeutics compare to Cellectis?

Summary

How does Pliant Therapeutics compare to Neumora Therapeutics?

Summary

How does Pliant Therapeutics compare to Bicycle Therapeutics?

Summary

How does Pliant Therapeutics compare to Lyell Immunopharma?

Summary

How does Pliant Therapeutics compare to Entrada Therapeutics?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

PLRX vs. The Competition

Pliant Therapeutics Competitors List

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Pliant Therapeutics (PLRX) Competitors

PLRX vs. CLLS, NMRA, BCYC, LYEL, and TRDA

How does Pliant Therapeutics compare to Cellectis?

Which has more volatility and risk, PLRX or CLLS?

Do insiders and institutionals believe in PLRX or CLLS?

Do analysts rate PLRX or CLLS?

Is PLRX or CLLS more profitable?

Which has higher earnings and valuation, PLRX or CLLS?

Does the media prefer PLRX or CLLS?

Summary

How does Pliant Therapeutics compare to Neumora Therapeutics?

Is NMRA or PLRX more profitable?

Do analysts prefer NMRA or PLRX?

Which has more volatility and risk, NMRA or PLRX?

Does the media prefer NMRA or PLRX?

Do institutionals and insiders believe in NMRA or PLRX?

Which has better earnings & valuation, NMRA or PLRX?

Summary

How does Pliant Therapeutics compare to Bicycle Therapeutics?

Which has stronger earnings and valuation, BCYC or PLRX?

Do institutionals & insiders hold more shares of BCYC or PLRX?

Is BCYC or PLRX more profitable?

Does the media favor BCYC or PLRX?

Which has more volatility and risk, BCYC or PLRX?

Do analysts recommend BCYC or PLRX?

Summary

How does Pliant Therapeutics compare to Lyell Immunopharma?

Which has better valuation & earnings, PLRX or LYEL?

Do analysts recommend PLRX or LYEL?

Do insiders and institutionals believe in PLRX or LYEL?

Is PLRX or LYEL more profitable?

Does the media refer more to PLRX or LYEL?

Which has more volatility & risk, PLRX or LYEL?

Summary

How does Pliant Therapeutics compare to Entrada Therapeutics?

Does the media favor TRDA or PLRX?

Which has more volatility and risk, TRDA or PLRX?

Do insiders and institutionals have more ownership in TRDA or PLRX?

Do analysts rate TRDA or PLRX?

Which has better valuation and earnings, TRDA or PLRX?

Is TRDA or PLRX more profitable?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

PLRX vs. The Competition

Pliant Therapeutics Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools