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Pliant Therapeutics (PLRX) Competitors

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$1.12 -0.02 (-1.32%)
Closing price 09/23/2026 04:00 PM Eastern
Extended Trading
$1.14 +0.02 (+1.69%)
As of 04:09 AM Eastern
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PLRX vs. GLSI, ANIK, PYXS, ACIU, and IVVD

Should you buy Pliant Therapeutics stock or one of its competitors? Pliant Therapeutics's main competitors and comparable companies include Greenwich LifeSciences (GLSI), Anika Therapeutics (ANIK), Pyxis Oncology (PYXS), AC Immune (ACIU), and Invivyd (IVVD). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Pliant Therapeutics compare to Greenwich LifeSciences?

Greenwich LifeSciences (NASDAQ:GLSI) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, earnings, institutional ownership, profitability, dividends, risk, analyst recommendations and media sentiment.

Pliant Therapeutics' return on equity of -52.17% beat Greenwich LifeSciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Greenwich LifeSciencesN/A -793.81% -295.32%
Pliant Therapeutics N/A -52.17%-40.46%

In the previous week, Pliant Therapeutics had 1 more articles in the media than Greenwich LifeSciences. MarketBeat recorded 1 mentions for Pliant Therapeutics and 0 mentions for Greenwich LifeSciences. Pliant Therapeutics' average media sentiment score of -0.09 beat Greenwich LifeSciences' score of -1.32 indicating that Pliant Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Greenwich LifeSciences Negative
Pliant Therapeutics Neutral

Greenwich LifeSciences is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Greenwich LifeSciencesN/AN/A-$19.36M-$1.54N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.49N/A

Greenwich LifeSciences has a beta of 1.47, meaning that its stock price is 47% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.27, meaning that its stock price is 27% more volatile than the broader market.

4.2% of Greenwich LifeSciences shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 51.5% of Greenwich LifeSciences shares are held by insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Greenwich LifeSciences currently has a consensus price target of $69.00, suggesting a potential upside of 294.06%. Pliant Therapeutics has a consensus price target of $3.00, suggesting a potential upside of 166.67%. Given Greenwich LifeSciences' stronger consensus rating and higher possible upside, equities research analysts clearly believe Greenwich LifeSciences is more favorable than Pliant Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Greenwich LifeSciences
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Pliant Therapeutics
2 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75

Summary

Pliant Therapeutics beats Greenwich LifeSciences on 7 of the 12 factors compared between the two stocks.

How does Pliant Therapeutics compare to Anika Therapeutics?

Anika Therapeutics (NASDAQ:ANIK) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their profitability, institutional ownership, earnings, risk, dividends, valuation, analyst recommendations and media sentiment.

91.5% of Anika Therapeutics shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 12.1% of Anika Therapeutics shares are held by insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Anika Therapeutics has higher revenue and earnings than Pliant Therapeutics. Anika Therapeutics is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Anika Therapeutics$112.82M2.42-$10.88M-$0.27N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.49N/A

Pliant Therapeutics has a net margin of 0.00% compared to Anika Therapeutics' net margin of -3.14%. Anika Therapeutics' return on equity of 0.20% beat Pliant Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Anika Therapeutics-3.14% 0.20% 0.15%
Pliant Therapeutics N/A -52.17%-40.46%

In the previous week, Anika Therapeutics had 2 more articles in the media than Pliant Therapeutics. MarketBeat recorded 3 mentions for Anika Therapeutics and 1 mentions for Pliant Therapeutics. Anika Therapeutics' average media sentiment score of 0.53 beat Pliant Therapeutics' score of -0.09 indicating that Anika Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Anika Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pliant Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Anika Therapeutics currently has a consensus price target of $22.00, suggesting a potential upside of 7.95%. Pliant Therapeutics has a consensus price target of $3.00, suggesting a potential upside of 166.67%. Given Pliant Therapeutics' higher probable upside, analysts plainly believe Pliant Therapeutics is more favorable than Anika Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Anika Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75
Pliant Therapeutics
2 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75

Anika Therapeutics has a beta of 0.2, indicating that its share price is 80% less volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.27, indicating that its share price is 27% more volatile than the broader market.

Summary

Anika Therapeutics beats Pliant Therapeutics on 11 of the 16 factors compared between the two stocks.

How does Pliant Therapeutics compare to Pyxis Oncology?

Pyxis Oncology (NASDAQ:PYXS) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, earnings, dividends, risk, valuation, analyst recommendations, institutional ownership and media sentiment.

In the previous week, Pyxis Oncology had 1 more articles in the media than Pliant Therapeutics. MarketBeat recorded 2 mentions for Pyxis Oncology and 1 mentions for Pliant Therapeutics. Pliant Therapeutics' average media sentiment score of -0.09 beat Pyxis Oncology's score of -0.40 indicating that Pliant Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pyxis Oncology
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Pliant Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Pyxis Oncology has a beta of 1.34, meaning that its stock price is 34% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.27, meaning that its stock price is 27% more volatile than the broader market.

39.1% of Pyxis Oncology shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 5.7% of Pyxis Oncology shares are held by company insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Pyxis Oncology presently has a consensus target price of $8.75, suggesting a potential upside of 171.74%. Pliant Therapeutics has a consensus target price of $3.00, suggesting a potential upside of 166.67%. Given Pyxis Oncology's stronger consensus rating and higher possible upside, analysts plainly believe Pyxis Oncology is more favorable than Pliant Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70
Pliant Therapeutics
2 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75

Pyxis Oncology has higher revenue and earnings than Pliant Therapeutics. Pyxis Oncology is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pyxis Oncology$13.86M19.38-$79.62M-$1.41N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.49N/A

Pliant Therapeutics' return on equity of -52.17% beat Pyxis Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
Pyxis OncologyN/A -215.23% -112.19%
Pliant Therapeutics N/A -52.17%-40.46%

Summary

Pyxis Oncology beats Pliant Therapeutics on 8 of the 14 factors compared between the two stocks.

How does Pliant Therapeutics compare to AC Immune?

AC Immune (NASDAQ:ACIU) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their valuation, profitability, earnings, media sentiment, risk, analyst recommendations, institutional ownership and dividends.

AC Immune has a beta of 1.6, meaning that its stock price is 60% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.27, meaning that its stock price is 27% more volatile than the broader market.

AC Immune currently has a consensus price target of $7.50, suggesting a potential upside of 165.02%. Pliant Therapeutics has a consensus price target of $3.00, suggesting a potential upside of 166.67%. Given Pliant Therapeutics' higher possible upside, analysts clearly believe Pliant Therapeutics is more favorable than AC Immune.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
AC Immune
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Pliant Therapeutics
2 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75

AC Immune has higher revenue and earnings than Pliant Therapeutics. AC Immune is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AC Immune$4.31M66.82-$85.03M-$0.54N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.49N/A

Pliant Therapeutics has a net margin of 0.00% compared to AC Immune's net margin of -245.32%. Pliant Therapeutics' return on equity of -52.17% beat AC Immune's return on equity.

Company Net Margins Return on Equity Return on Assets
AC Immune-245.32% -100.17% -28.36%
Pliant Therapeutics N/A -52.17%-40.46%

In the previous week, AC Immune had 6 more articles in the media than Pliant Therapeutics. MarketBeat recorded 7 mentions for AC Immune and 1 mentions for Pliant Therapeutics. AC Immune's average media sentiment score of 1.19 beat Pliant Therapeutics' score of -0.09 indicating that AC Immune is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
AC Immune
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pliant Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

51.4% of AC Immune shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 4.6% of AC Immune shares are held by insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Summary

AC Immune beats Pliant Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Pliant Therapeutics compare to Invivyd?

Invivyd (NASDAQ:IVVD) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, dividends, valuation, institutional ownership, earnings, media sentiment, profitability and risk.

70.4% of Invivyd shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 12.3% of Invivyd shares are held by insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Invivyd has higher revenue and earnings than Pliant Therapeutics. Invivyd is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Invivyd$53.43M5.09-$52.49M-$0.33N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.49N/A

Invivyd has a beta of 0.81, indicating that its stock price is 19% less volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.27, indicating that its stock price is 27% more volatile than the broader market.

Pliant Therapeutics has a net margin of 0.00% compared to Invivyd's net margin of -183.90%. Pliant Therapeutics' return on equity of -52.17% beat Invivyd's return on equity.

Company Net Margins Return on Equity Return on Assets
Invivyd-183.90% -59.73% -48.97%
Pliant Therapeutics N/A -52.17%-40.46%

In the previous week, Invivyd and Invivyd both had 1 articles in the media. Invivyd's average media sentiment score of 1.34 beat Pliant Therapeutics' score of -0.09 indicating that Invivyd is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Invivyd
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pliant Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Invivyd presently has a consensus target price of $8.00, indicating a potential upside of 766.65%. Pliant Therapeutics has a consensus target price of $3.00, indicating a potential upside of 166.67%. Given Invivyd's stronger consensus rating and higher probable upside, equities research analysts clearly believe Invivyd is more favorable than Pliant Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Invivyd
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Pliant Therapeutics
2 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75

Summary

Invivyd beats Pliant Therapeutics on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PLRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PLRX vs. The Competition

MetricPliant TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$70.59M$3.98B$7.31B$13.28B
Dividend YieldN/A3.63%2.52%12.57%
P/E Ratio-0.7613.88274.1025.70
Price / SalesN/A1,437.48672.6190.85
Price / CashN/A113.2977.8052.76
Price / Book0.3815.4510.486.32
Net Income-$149.34M-$22.82M$3.49B$359.73M
7 Day Performance-0.44%-1.68%-0.68%0.17%
1 Month Performance-1.32%-6.15%-3.18%-3.27%
1 Year Performance-22.95%30.67%15.13%5.58%

Pliant Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PLRX
Pliant Therapeutics
1.4759 of 5 stars
$1.13
-1.3%
$3.00
+166.7%
-22.9%$70.59MN/AN/A49
GLSI
Greenwich LifeSciences
2.0681 of 5 stars
$19.12
+2.9%
$69.00
+260.9%
+59.5%$280.84MN/AN/A13
ANIK
Anika Therapeutics
3.3818 of 5 stars
$20.94
+1.2%
$22.00
+5.1%
+123.5%$280.38M$112.82MN/A235
PYXS
Pyxis Oncology
3.0706 of 5 stars
$3.33
+4.3%
$8.75
+163.1%
+47.0%$277.67M$13.86MN/A56
ACIU
AC Immune
3.2028 of 5 stars
$2.73
+2.8%
$7.50
+175.2%
+12.3%$277.32M$4.31MN/A106

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This page (NASDAQ:PLRX) was last updated on 9/24/2026 by MarketBeat.com Staff.
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