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Pliant Therapeutics (PLRX) Competitors

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$1.09 +0.01 (+0.93%)
Closing price 07/24/2026 04:00 PM Eastern
Extended Trading
$1.09 0.00 (0.00%)
As of 07/24/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PLRX vs. MGNX, GLSI, ALXO, NAGE, and SRZN

Should you buy Pliant Therapeutics stock or one of its competitors? MarketBeat compares Pliant Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Pliant Therapeutics include MacroGenics (MGNX), Greenwich LifeSciences (GLSI), ALX Oncology (ALXO), Niagen Bioscience (NAGE), and Surrozen (SRZN). These companies are all part of the "pharmaceutical products" industry.

How does Pliant Therapeutics compare to MacroGenics?

Pliant Therapeutics (NASDAQ:PLRX) and MacroGenics (NASDAQ:MGNX) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their profitability, media sentiment, valuation, earnings, institutional ownership, analyst recommendations, risk and dividends.

97.3% of Pliant Therapeutics shares are owned by institutional investors. Comparatively, 96.9% of MacroGenics shares are owned by institutional investors. 8.7% of Pliant Therapeutics shares are owned by insiders. Comparatively, 13.6% of MacroGenics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

MacroGenics has higher revenue and earnings than Pliant Therapeutics. MacroGenics is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pliant TherapeuticsN/AN/A-$149.34M-$1.84N/A
MacroGenics$157.08M1.50-$74.62M-$1.10N/A

Pliant Therapeutics has a beta of 1.21, suggesting that its stock price is 21% more volatile than the broader market. Comparatively, MacroGenics has a beta of 1.18, suggesting that its stock price is 18% more volatile than the broader market.

Pliant Therapeutics has a net margin of 0.00% compared to MacroGenics' net margin of -44.79%. Pliant Therapeutics' return on equity of -58.11% beat MacroGenics' return on equity.

Company Net Margins Return on Equity Return on Assets
Pliant TherapeuticsN/A -58.11% -44.37%
MacroGenics -44.79%-147.80%-28.40%

Pliant Therapeutics presently has a consensus price target of $3.00, suggesting a potential upside of 175.23%. MacroGenics has a consensus price target of $5.50, suggesting a potential upside of 48.65%. Given Pliant Therapeutics' higher probable upside, research analysts plainly believe Pliant Therapeutics is more favorable than MacroGenics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pliant Therapeutics
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80
MacroGenics
1 Sell rating(s)
3 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.29

In the previous week, MacroGenics had 2 more articles in the media than Pliant Therapeutics. MarketBeat recorded 5 mentions for MacroGenics and 3 mentions for Pliant Therapeutics. Pliant Therapeutics' average media sentiment score of 1.08 beat MacroGenics' score of 0.37 indicating that Pliant Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pliant Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
MacroGenics
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

MacroGenics beats Pliant Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Pliant Therapeutics compare to Greenwich LifeSciences?

Greenwich LifeSciences (NASDAQ:GLSI) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their risk, media sentiment, valuation, dividends, analyst recommendations, earnings, profitability and institutional ownership.

Greenwich LifeSciences has a beta of 1.4, indicating that its share price is 40% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, indicating that its share price is 21% more volatile than the broader market.

Greenwich LifeSciences presently has a consensus target price of $57.00, indicating a potential upside of 339.14%. Pliant Therapeutics has a consensus target price of $3.00, indicating a potential upside of 175.23%. Given Greenwich LifeSciences' stronger consensus rating and higher possible upside, equities research analysts clearly believe Greenwich LifeSciences is more favorable than Pliant Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Greenwich LifeSciences
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Pliant Therapeutics
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80

Pliant Therapeutics' return on equity of -58.11% beat Greenwich LifeSciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Greenwich LifeSciencesN/A -941.15% -368.53%
Pliant Therapeutics N/A -58.11%-44.37%

Greenwich LifeSciences is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Greenwich LifeSciencesN/AN/A-$19.36M-$1.57N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.84N/A

In the previous week, Greenwich LifeSciences had 16 more articles in the media than Pliant Therapeutics. MarketBeat recorded 19 mentions for Greenwich LifeSciences and 3 mentions for Pliant Therapeutics. Pliant Therapeutics' average media sentiment score of 1.08 beat Greenwich LifeSciences' score of 0.77 indicating that Pliant Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Greenwich LifeSciences
4 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Pliant Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

4.2% of Greenwich LifeSciences shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 51.5% of Greenwich LifeSciences shares are held by insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Greenwich LifeSciences beats Pliant Therapeutics on 8 of the 13 factors compared between the two stocks.

How does Pliant Therapeutics compare to ALX Oncology?

ALX Oncology (NASDAQ:ALXO) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their risk, valuation, analyst recommendations, earnings, media sentiment, profitability, institutional ownership and dividends.

ALX Oncology has a beta of 0.42, indicating that its stock price is 58% less volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, indicating that its stock price is 21% more volatile than the broader market.

In the previous week, ALX Oncology and ALX Oncology both had 3 articles in the media. Pliant Therapeutics' average media sentiment score of 1.08 beat ALX Oncology's score of 0.97 indicating that Pliant Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
ALX Oncology
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pliant Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

ALX Oncology currently has a consensus price target of $4.60, indicating a potential upside of 126.60%. Pliant Therapeutics has a consensus price target of $3.00, indicating a potential upside of 175.23%. Given Pliant Therapeutics' higher possible upside, analysts plainly believe Pliant Therapeutics is more favorable than ALX Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
ALX Oncology
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.67
Pliant Therapeutics
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80

98.0% of ALX Oncology shares are held by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are held by institutional investors. 21.0% of ALX Oncology shares are held by company insiders. Comparatively, 8.7% of Pliant Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Pliant Therapeutics' return on equity of -58.11% beat ALX Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
ALX OncologyN/A -124.06% -85.57%
Pliant Therapeutics N/A -58.11%-44.37%

ALX Oncology is trading at a lower price-to-earnings ratio than Pliant Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ALX OncologyN/AN/A-$101.69M-$1.49N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.84N/A

Summary

ALX Oncology and Pliant Therapeutics tied by winning 6 of the 12 factors compared between the two stocks.

How does Pliant Therapeutics compare to Niagen Bioscience?

Niagen Bioscience (NASDAQ:NAGE) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their institutional ownership, analyst recommendations, valuation, profitability, risk, dividends, media sentiment and earnings.

15.4% of Niagen Bioscience shares are owned by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are owned by institutional investors. 10.0% of Niagen Bioscience shares are owned by insiders. Comparatively, 8.7% of Pliant Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

In the previous week, Pliant Therapeutics had 1 more articles in the media than Niagen Bioscience. MarketBeat recorded 3 mentions for Pliant Therapeutics and 2 mentions for Niagen Bioscience. Pliant Therapeutics' average media sentiment score of 1.08 beat Niagen Bioscience's score of 0.94 indicating that Pliant Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Niagen Bioscience
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pliant Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Niagen Bioscience currently has a consensus target price of $10.50, indicating a potential upside of 227.10%. Pliant Therapeutics has a consensus target price of $3.00, indicating a potential upside of 175.23%. Given Niagen Bioscience's stronger consensus rating and higher probable upside, equities research analysts plainly believe Niagen Bioscience is more favorable than Pliant Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Niagen Bioscience
0 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
3.00
Pliant Therapeutics
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80

Niagen Bioscience has higher revenue and earnings than Pliant Therapeutics. Pliant Therapeutics is trading at a lower price-to-earnings ratio than Niagen Bioscience, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Niagen Bioscience$129.42M1.98$17.38M$0.2115.29
Pliant TherapeuticsN/AN/A-$149.34M-$1.84N/A

Niagen Bioscience has a beta of 2.09, suggesting that its stock price is 109% more volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, suggesting that its stock price is 21% more volatile than the broader market.

Niagen Bioscience has a net margin of 14.29% compared to Pliant Therapeutics' net margin of 0.00%. Niagen Bioscience's return on equity of 22.68% beat Pliant Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Niagen Bioscience14.29% 22.68% 16.23%
Pliant Therapeutics N/A -58.11%-44.37%

Summary

Niagen Bioscience beats Pliant Therapeutics on 13 of the 16 factors compared between the two stocks.

How does Pliant Therapeutics compare to Surrozen?

Surrozen (NASDAQ:SRZN) and Pliant Therapeutics (NASDAQ:PLRX) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, analyst recommendations, risk, profitability, valuation, earnings and dividends.

Pliant Therapeutics has lower revenue, but higher earnings than Surrozen. Pliant Therapeutics is trading at a lower price-to-earnings ratio than Surrozen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Surrozen$7.49M30.57-$242.03M-$37.59N/A
Pliant TherapeuticsN/AN/A-$149.34M-$1.84N/A

Surrozen presently has a consensus price target of $42.00, indicating a potential upside of 112.87%. Pliant Therapeutics has a consensus price target of $3.00, indicating a potential upside of 175.23%. Given Pliant Therapeutics' higher probable upside, analysts plainly believe Pliant Therapeutics is more favorable than Surrozen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Surrozen
2 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.50
Pliant Therapeutics
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80

Pliant Therapeutics has a net margin of 0.00% compared to Surrozen's net margin of -4,810.50%. Surrozen's return on equity of 0.00% beat Pliant Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Surrozen-4,810.50% N/A -154.08%
Pliant Therapeutics N/A -58.11%-44.37%

Surrozen has a beta of 0.51, meaning that its stock price is 49% less volatile than the broader market. Comparatively, Pliant Therapeutics has a beta of 1.21, meaning that its stock price is 21% more volatile than the broader market.

66.6% of Surrozen shares are owned by institutional investors. Comparatively, 97.3% of Pliant Therapeutics shares are owned by institutional investors. 31.7% of Surrozen shares are owned by company insiders. Comparatively, 8.7% of Pliant Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Surrozen and Surrozen both had 3 articles in the media. Pliant Therapeutics' average media sentiment score of 1.08 beat Surrozen's score of 0.63 indicating that Pliant Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Surrozen
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pliant Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Pliant Therapeutics beats Surrozen on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PLRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PLRX vs. The Competition

MetricPliant TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$66.87M$3.67B$6.86B$12.25B
Dividend YieldN/A2.19%2.67%9.79%
P/E Ratio-0.5921.4827.1423.64
Price / SalesN/A169.92517.0189.03
Price / CashN/A157.9050.5459.64
Price / Book0.377.8810.286.07
Net Income-$149.34M$23.86M$3.60B$331.99M
7 Day Performance-5.22%-3.82%-1.27%-0.63%
1 Month Performance-3.54%-2.61%-0.37%-2.00%
1 Year Performance-30.57%32.79%18.30%13.62%

Pliant Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PLRX
Pliant Therapeutics
2.4585 of 5 stars
$1.09
+0.9%
$3.00
+175.2%
-31.4%$66.87MN/AN/A90
MGNX
MacroGenics
2.642 of 5 stars
$4.44
-1.4%
$5.50
+24.0%
+107.9%$280.17M$149.50MN/A430
GLSI
Greenwich LifeSciences
1.9036 of 5 stars
$18.67
+0.5%
$47.50
+154.5%
+13.0%$274.78MN/AN/A3
ALXO
ALX Oncology
2.0326 of 5 stars
$2.00
+1.3%
$4.60
+130.6%
+275.9%$268.45MN/AN/A40
NAGE
Niagen Bioscience
4.2586 of 5 stars
$3.37
-3.0%
$10.50
+212.0%
-65.4%$267.99M$129.42M16.02120

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This page (NASDAQ:PLRX) was last updated on 7/25/2026 by MarketBeat.com Staff.
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