Ishara Investments Lp Top Holdings and 13F Report (2026) About Ishara Investments LpInvestment ActivityIshara Investments Lp has $136.10 million in total holdings as of June 30, 2026.Ishara Investments Lp owns shares of 41 different stocks, but just 21 companies or ETFs make up 80% of its holdings.Approximately 49.47% of the portfolio was purchased this quarter.About 41.89% of the portfolio was sold this quarter.This quarter, Ishara Investments Lp has purchased 36 new stocks and bought additional shares in 13 stocks.Ishara Investments Lp sold shares of 9 stocks and completely divested from 11 stocks this quarter.Largest Holdings ACADIA Pharmaceuticals $10,373,000Xeris Biopharma $9,741,600BioMarin Pharmaceutical $8,211,070PRAXIS PRECISION MEDICINES I $7,549,515Ultragenyx Pharmaceutical $6,844,950 Largest New Holdings this Quarter 00847X104 - Agios Pharmaceuticals $6,086,040 Holding457669307 - Insmed $5,464,275 Holding22663K107 - Crinetics Pharmaceuticals $5,369,770 Holding890260839 - TONIX PHARMACEUTICALS HLDG C $4,316,070 Holding10806X102 - BridgeBio Pharma $4,275,152 Holding Largest Purchases this Quarter ACADIA Pharmaceuticals 287,000 shares (about $7.26M)Agios Pharmaceuticals 164,000 shares (about $6.09M)Insmed 51,250 shares (about $5.46M)Crinetics Pharmaceuticals 143,500 shares (about $5.37M)TONIX PHARMACEUTICALS HLDG C 338,250 shares (about $4.32M) Largest Sales this Quarter PRAXIS PRECISION MEDICINES I 20,500 shares (about $6.86M)Axsome Therapeutics 24,600 shares (about $6.02M)Silence Therapeutics 85,150 shares (about $3.75M)Vera Therapeutics 71,750 shares (about $3.08M)Travere Therapeutics 28,700 shares (about $1.63M) Sector Allocation Over TimeMap of 500 Largest Holdings ofIshara Investments Lp Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorACADACADIA Pharmaceuticals$10,373,000$7,261,100 â–²233.3%410,0007.6%HealthcareXERSXeris Biopharma$9,741,600$1,623,600 â–²20.0%1,230,0007.2%HealthcareBMRNBioMarin Pharmaceutical$8,211,070$3,519,030 â–²75.0%143,5006.0%HealthcarePRAXIS PRECISION MEDICINES I$7,549,515$6,863,195 â–¼-47.6%22,5505.5%COM NEWRAREUltragenyx Pharmaceutical$6,844,950$1,026,743 â–²17.6%205,0005.0%HealthcareAGIOAgios Pharmaceuticals$6,086,040$6,086,040 â–²New Holding164,0004.5%HealthcareINSMInsmed$5,464,275$5,464,275 â–²New Holding51,2504.0%HealthcareCRNXCrinetics Pharmaceuticals$5,369,770$5,369,770 â–²New Holding143,5003.9%HealthcareZNTLZentalis Pharmaceuticals$4,971,250$994,250 â–¼-16.7%1,025,0003.7%HealthcarePCVXVaxcyte$4,766,660$1,429,998 â–²42.9%82,0003.5%HealthcareANNXAnnexon$4,682,200$3,687,233 â–²370.6%820,0003.4%HealthcareTVTXTravere Therapeutics$4,658,420$1,630,447 â–¼-25.9%82,0003.4%HealthcareTONIX PHARMACEUTICALS HLDG C$4,316,070$4,316,070 â–²New Holding338,2503.2%COM NEWBBIOBridgeBio Pharma$4,275,152$4,275,152 â–²New Holding57,4003.1%HealthcareAXSMAxsome Therapeutics$4,014,228$6,021,342 â–¼-60.0%16,4002.9%HealthcareCONTINEUM THERAPEUTICS INC$3,359,950$1,032,570 â–²44.4%205,0002.5%CL ALXRXLexicon Pharmaceuticals$3,050,400$885,600 â–²40.9%1,271,0002.2%HealthcareKURAKura Oncology$3,035,948$3,035,948 â–²New Holding276,7502.2%HealthcareDBV TECHNOLOGIES S A$3,025,800$1,344,800 â–²80.0%184,5002.2%SPONSORED ADSGMABGenmab A/S$2,815,675$563,135 â–²25.0%102,5002.1%HealthcareCYTKCytokinetics$2,794,232$2,794,232 â–²New Holding32,8002.1%HealthcareMLYSMineralys Therapeutics$2,765,450$553,090 â–²25.0%102,5002.0%HealthcareSLNSilence Therapeutics$2,434,847$3,745,749 â–¼-60.6%55,3501.8%HealthcareNUVBNuvation Bio$2,095,920$2,095,920 â–²New Holding369,0001.5%HealthcareWVEWAVE Life Sciences$1,905,680$1,905,680 â–²New Holding328,0001.4%HealthcareNEKTAR THERAPEUTICS$1,860,437$1,860,437 â–²New Holding26,6501.4%COM NEWSRRKScholar Rock$1,691,250$1,465,750 â–¼-46.4%30,7501.2%HealthcareELVNEnliven Therapeutics$1,664,600$1,664,600 â–²New Holding32,8001.2%HealthcareALNYAlnylam Pharmaceuticals$1,542,7790.0%5,1251.1%HealthcareBEAMBeam Therapeutics$1,407,120$562,848 â–¼-28.6%41,0001.0%HealthcareSIONNA THERAPEUTICS INC$1,350,540$810,324 â–²150.0%123,0001.0%COMORICOric Pharmaceuticals$1,332,090$222,015 â–²20.0%123,0001.0%HealthcareNAMSNewAmsterdam Pharma$1,250,5410.0%36,9000.9%HealthcareVRTXVertex Pharmaceuticals$1,221,956$1,221,956 â–²New Holding2,4600.9%HealthcareSPRYARS Pharmaceuticals$1,149,355$1,149,355 â–²New Holding143,4900.8%HealthcareMONOPAR THERAPEUTICS INC$1,138,857$1,138,857 â–²New Holding12,3000.8%COM NEWERASErasca$751,120$751,120 â–²New Holding41,0000.6%HealthcareVERAVera Therapeutics$439,828$3,078,796 â–¼-87.5%10,2500.3%HealthcareIMTXImmatics$311,498$1,245,992 â–¼-80.0%30,7500.2%HealthcareMREOMereo BioPharma Group$244,232$244,232 â–²New Holding768,7500.2%HealthcareGOSSGossamer Bio$134,9720.0%820,0000.1%HealthcareKALVKalVista Pharmaceuticals$0$5,570,978 â–¼-100.0%00.0%HealthcareFOLDAmicus Therapeutics$0$5,335,740 â–¼-100.0%00.0%HealthcareVSTMVerastem$0$4,346,000 â–¼-100.0%00.0%HealthcareARWRArrowhead Pharmaceuticals$0$3,470,445 â–¼-100.0%00.0%HealthcareMLTXMoonLake Immunotherapeutics$0$3,248,020 â–¼-100.0%00.0%HealthcareARDXArdelyx$0$2,701,490 â–¼-100.0%00.0%HealthcareCPRXCatalyst Pharmaceuticals$0$2,030,320 â–¼-100.0%00.0%HealthcareLGNDLigand Pharmaceuticals$0$1,637,130 â–¼-100.0%00.0%HealthcareEWTXEdgewise Therapeutics$0$1,549,800 â–¼-100.0%00.0%HealthcareIDYAIDEAYA Biosciences$0$819,672 â–¼-100.0%00.0%HealthcarePTCTPTC Therapeutics$0$698,333 â–¼-100.0%00.0%HealthcareShowing largest 100 holdings. 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