Sio Capital Management, LLC Top Holdings and 13F Report (2025) About Sio Capital Management, LLCInvestment ActivitySio Capital Management, LLC has $261.84 million in total holdings as of June 30, 2025.Sio Capital Management, LLC owns shares of 52 different stocks, but just 19 companies or ETFs make up 80% of its holdings.Approximately 35.03% of the portfolio was purchased this quarter.About 62.17% of the portfolio was sold this quarter.This quarter, Sio Capital Management, LLC has purchased 54 new stocks and bought additional shares in 31 stocks.Sio Capital Management, LLC sold shares of 6 stocks and completely divested from 12 stocks this quarter.Largest Holdings Maximus $38,475,637Disc Medicine $15,082,320Globus Medical $14,493,541Centene $14,248,500Merck & Co., Inc. $13,769,961 Largest New Holdings this Quarter 15135B101 - Centene $14,248,500 Holding45168D104 - IDEXX Laboratories $9,654,120 Holding80105N105 - Sanofi $9,058,125 Holding28036F105 - Edgewise Therapeutics $7,075,860 HoldingN5749R100 - Merus $3,299,019 Holding Largest Purchases this Quarter Centene 262,500 shares (about $14.25M)Disc Medicine 211,276 shares (about $11.19M)IDEXX Laboratories 18,000 shares (about $9.65M)Sanofi 187,500 shares (about $9.06M)Edgewise Therapeutics 539,730 shares (about $7.08M) Largest Sales this Quarter Neurocrine Biosciences 86,848 shares (about $10.92M)Embecta 1,076,444 shares (about $10.43M)Merck & Co., Inc. 96,645 shares (about $7.65M)Ventyx Biosciences 1,274,691 shares (about $2.73M)SEPTERNA INC 204,235 shares (about $2.16M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSio Capital Management, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorMMSMaximus$38,475,637$5,597,327 ▲17.0%548,08614.7%Business ServicesIRONDisc Medicine$15,082,320$11,189,177 ▲287.4%284,7875.8%MedicalGMEDGlobus Medical$14,493,541$2,276,401 ▲18.6%245,5705.5%MedicalCNCCentene$14,248,500$14,248,500 ▲New Holding262,5005.4%MedicalMRKMerck & Co., Inc.$13,769,961$7,650,418 ▼-35.7%173,9515.3%MedicalBRIGHT MINDS BIOSCIENCES INC$13,377,145$124,701 ▲0.9%512,3385.1%COM NEWNBIXNeurocrine Biosciences$12,660,125$10,915,925 ▼-46.3%100,7254.8%MedicalBMRNBioMarin Pharmaceutical$12,374,517$4,616,381 ▲59.5%225,1144.7%MedicalANNXAnnexon$9,829,834$1,675,147 ▲20.5%4,095,7643.8%MedicalIDXXIDEXX Laboratories$9,654,120$9,654,120 ▲New Holding18,0003.7%MedicalSNYSanofi$9,058,125$9,058,125 ▲New Holding187,5003.5%MedicalTYRATyra Biosciences$7,754,322$3,767,297 ▲94.5%810,2743.0%MedicalANIPANI Pharmaceuticals$7,368,226$1,672,031 ▲29.4%112,9232.8%MedicalEWTXEdgewise Therapeutics$7,075,860$7,075,860 ▲New Holding539,7302.7%MedicalANTERIS TECHNOLOGIES GLOBAL$6,969,893$2,012,255 ▼-22.4%1,839,0222.7%COMSEPTERNA INC$6,177,478$2,158,764 ▼-25.9%584,4352.4%COMAORTArtivion$4,936,690$1,168,054 ▲31.0%158,7361.9%MedicalDIANTHUS THERAPEUTICS INC$4,397,984$2,218,330 ▲101.8%236,0701.7%COMPRQRProQR Therapeutics$4,233,284$41,914 ▲1.0%2,075,1391.6%MedicalPMVPPMV Pharmaceuticals$3,959,5200.0%3,735,3961.5%MedicalAVNSAVANOS MEDICAL$3,535,512$35,006 ▲1.0%288,8491.4%MedicalMRUSMerus$3,299,019$3,299,019 ▲New Holding62,7191.3%MedicalAQSTAquestive Therapeutics$3,136,189$1,839,897 ▲141.9%947,4891.2%MedicalINMBINmune Bio$3,001,383$3,001,383 ▲New Holding1,299,3001.1%MedicalVTYXVentyx Biosciences$2,799,043$2,727,839 ▼-49.4%1,307,9641.1%MedicalMBX BIOSCIENCES INC$2,749,810$2,749,810 ▲New Holding241,0001.1%COMIDYAIDEAYA Biosciences$2,611,315$25,855 ▲1.0%124,2301.0%MedicalALIGOS THERAPEUTICS INC$2,422,106$1,119,115 ▲85.9%335,9370.9%COM NEWVIRVir Biotechnology$2,410,849$23,869 ▲1.0%478,3430.9%MedicalNMTCNeuroOne Medical Technologies$2,390,101$2,390,101 ▲New Holding3,523,6630.9%MedicalSENSSenseonics$2,311,635$2,311,635 ▲New Holding4,852,2980.9%MedicalTVTXTravere Therapeutics$1,808,708$17,908 ▲1.0%122,2100.7%MedicalERASErasca$1,739,580$17,224 ▲1.0%1,369,7480.7%MedicalATXSAstria Therapeutics$1,705,852$16,889 ▲1.0%318,2560.7%MedicalSVRASavara$1,657,220$16,409 ▲1.0%726,8510.6%MedicalENTAEnanta Pharmaceuticals$1,351,531$13,381 ▲1.0%178,7740.5%MedicalTELATELA Bio$1,234,422$12,222 ▲1.0%636,3000.5%MedicalALECAlector$1,183,743$11,721 ▲1.0%845,5310.5%MedicalCNTXContext Therapeutics$879,040$8,704 ▲1.0%1,341,6360.3%MedicalOVIDOvid Therapeutics$736,3370.0%2,232,0000.3%MedicalMODDModular Medical$585,439$397,706 ▲211.8%785,8240.2%MedicalFHTXFoghorn Therapeutics$577,578$5,720 ▲1.0%122,8890.2%MedicalAPREAprea Therapeutics$472,134$4,675 ▲1.0%279,3690.2%MedicalNYXHNyxoah$380,2760.0%50,8390.1%MedicalAVALO THERAPEUTICS INC$360,143$3,568 ▲1.0%72,1730.1%COM NEWEMBCEmbecta$302,028$10,430,756 ▼-97.2%31,1690.1%MedicalBOUNDLESS BIO INC$165,316$1,637 ▲1.0%163,6790.1%COMNXTCNextCure$60,398$598 ▲1.0%131,3000.0%MedicalTERNTerns Pharmaceuticals$37,673$373 ▲1.0%10,1000.0%MedicalHUMAWHumacyte$18,7490.0%49,9980.0%MedicalRCKTWRocket Pharmaceuticals$13,6200.0%400,0000.0%MedicalLIFEaTyr Pharma$5,577$5,577 ▲New Holding1,1000.0%MedicalICLRIcon$0$35,577,392 ▼-100.0%00.0%MedicalZBHZimmer Biomet$0$21,242,188 ▼-100.0%00.0%MedicalLABCORP HOLDINGS INC$0$19,520,602 ▼-100.0%00.0%COM SHSTFXTeleflex$0$14,894,118 ▼-100.0%00.0%MedicalHAEHaemonetics$0$8,513,539 ▼-100.0%00.0%MedicalTARAProtara Therapeutics$0$6,450,918 ▼-100.0%00.0%MedicalSLNOSoleno Therapeutics$0$5,594,535 ▼-100.0%00.0%MedicalPRAXIS PRECISION MEDICINES INC I$0$4,260,375 ▼-100.0%00.0%COM NEWETNB89BIO$0$3,635,000 ▼-100.0%00.0%MedicalAKROAkero Therapeutics$0$3,440,800 ▼-100.0%00.0%MedicalVXRTVaxart$0$2,272,463 ▼-100.0%00.0%MedicalIRWDIronwood Pharmaceuticals$0$1,495,896 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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