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Compare stocks with our powerful stock comparison tool. Analyze fundamentals, price performance, and key financial indicators to make informed investment decisions. Our tool lets you compare up to ten stocks side by side based on Performance Charts, Price & Volume, MarketRank™, Analyst Ratings, Sales & Book Value, Profitability & Earnings, Dividends, Debt, Ownership, Headlines, and more. Simply enter up to ten stock symbols (e.g., BAC, JPM, WFC, C, GS) to get started and uncover top investment opportunities.

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$53.36
-5.0%
$47.93
$21.02
$58.40
$4.48B-0.161.04 million shs1.69 million shs
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
$3.41
+7.2%
$3.41
$1.85
$6.30
$524.84M1.1826,463 shs3,000 shs
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$28.40
-2.2%
$30.76
$21.51
$56.00
$3.50B0.951.36 million shs946,287 shs
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
$3.10
+0.3%
$3.01
$2.58
$4.92
$206.06M159,123 shs41,237 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
0.00%+3.67%+10.13%+38.81%+139.51%
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
0.00%0.00%0.00%0.00%+76.68%
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
0.00%-0.96%-6.29%-1.66%-28.94%
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
0.00%+1.64%+3.69%-6.93%-32.53%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
3.5179 of 5 stars
3.51.00.04.71.90.80.0
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
0.5221 of 5 stars
1.10.00.00.03.30.80.6
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
2.3382 of 5 stars
4.50.00.00.03.10.80.0
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
2.6147 of 5 stars
3.35.00.00.02.20.00.6
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
3.00
Buy$82.5054.61% Upside
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
2.17
Hold$1.33-60.90% Downside
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
3.06
Buy$65.59130.94% Upside
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
2.67
Moderate Buy$7.00125.81% Upside

Current Analyst Ratings Breakdown

Latest OPT, SOPH, RNA, and AKRO Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
6/27/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Cantor Fitzgerald
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Reiterated RatingOverweight ➝ Overweight$96.00
6/24/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Sanford C. Bernstein
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Initiated CoverageOutperform$50.00
6/17/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Wolfe Research
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Initiated CoverageOutperform$55.00
6/11/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Raymond James Financial
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Initiated CoverageStrong-Buy$65.00
6/10/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Citigroup
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Boost Price TargetBuy ➝ Buy$70.00 ➝ $75.00
6/10/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Barclays
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Boost Price TargetOverweight ➝ Overweight$57.00 ➝ $59.00
6/10/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
JPMorgan Chase & Co.
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Boost Price TargetOverweight ➝ Overweight$57.00 ➝ $59.00
6/9/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Bank of America
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Boost Price TargetBuy ➝ Buy$48.00 ➝ $54.00
6/9/2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
Chardan Capital
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Boost Price TargetBuy ➝ Buy$65.00 ➝ $75.00
5/27/2025
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
Bank of America
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Boost Price TargetBuy ➝ Buy$63.00 ➝ $64.00
5/13/2025
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
Citigroup
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Lower Price TargetBuy ➝ Buy$80.00 ➝ $78.00
(Data available from 6/30/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
N/AN/AN/AN/A$10.75 per shareN/A
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
$120K4,373.61N/AN/A($0.56) per share-6.09
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$10.90M314.02N/AN/A$11.94 per share2.38
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
$65.17M3.17N/AN/A$1.48 per share2.09
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
-$252.06M-$1.95N/AN/AN/AN/A-15.19%-13.97%8/8/2025 (Estimated)
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
-$220.24MN/A0.00N/AN/AN/AN/AN/A8/28/2025 (Estimated)
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
-$322.30M-$3.00N/AN/AN/A-4,136.00%-26.96%-24.57%8/8/2025 (Estimated)
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
-$62.49M-$1.00N/AN/AN/A-98.51%-63.47%-40.06%8/5/2025 (Estimated)

Latest OPT, SOPH, RNA, and AKRO Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/12/2025Q1 2025
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
-$1.01$0.90+$1.91$0.90N/AN/A
5/8/2025Q1 2025
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
-$0.88-$0.90-$0.02-$0.90$2.63 million$1.60 million
5/6/2025Q1 2025
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
-$0.21-$0.26-$0.05-$0.26$16.76 million$17.78 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
N/AN/AN/AN/AN/A
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
N/AN/AN/AN/AN/A
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
N/AN/AN/AN/AN/A
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
0.03
16.80
16.80
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
N/A
1.57
N/A
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
N/A
16.91
16.91
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
0.16
3.11
2.94

Institutional Ownership

CompanyInstitutional Ownership
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
N/A
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
55.95%
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
N/A
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
31.59%

Insider Ownership

CompanyInsider Ownership
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
7.07%
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
3.20%
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
3.83%
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
4.88%
CompanyEmployeesShares OutstandingFree FloatOptionable
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
3079.72 million74.08 millionOptionable
Opthea Limited Unsponsored ADR stock logo
OPT
Opthea
8153.91 million148.99 millionNot Optionable
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
190120.52 million115.90 millionOptionable
SOPHiA GENETICS SA stock logo
SOPH
SOPHiA GENETICS
52066.69 million63.43 millionNot Optionable

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Akero Therapeutics stock logo

Akero Therapeutics NASDAQ:AKRO

$53.36 -2.83 (-5.04%)
As of 04:00 PM Eastern

Akero Therapeutics, Inc., together with its subsidiary, engages in the development of treatments for patients with serious metabolic diseases in the United States. The company's lead product candidate is efruxifermin (EFX), which is in Phase 3 clinical trials that protects against cellular stress and regulates the metabolism of lipids, carbohydrates, and proteins throughout the body for the treatment of biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH) patients. It has a license agreement with Amgen Inc. to develop, manufacture, use, distribute, and sell EFX as a treatment for MASH and other metabolic diseases. The company was formerly known as Pippin Pharmaceuticals, Inc. and changed its name to Akero Therapeutics, Inc. in May 2018. Akero Therapeutics, Inc. was incorporated in 2017 and is headquartered in South San Francisco, California.

Opthea stock logo

Opthea NASDAQ:OPT

$3.41 +0.23 (+7.23%)
As of 06/27/2025

Opthea Limited, a clinical stage biopharmaceutical company, engages in the development and commercialization of therapies primarily for eye disease in Australia. The company's development activities are based on the intellectual property portfolio covering Vascular Endothelial Growth Factors (VEGF) VEGF-C, VEGF-D, and VEGF Receptor-3 for the treatment of diseases associated with blood and lymphatic vessel growth, as well as vascular leakage. Its lead product candidate is Sozinibercept (OPT 302), a soluble form of vascular endothelial growth factor receptor-3 VEGFR-3, currently under Phase 3 clinical development as a novel therapy for wet age-related macular degeneration and diabetic macular edema. The company was formerly known as Circadian Technologies Limited and changed its name to Opthea Limited in December 2015. Opthea Limited was incorporated in 1984 and is based in South Yarra, Australia.

Avidity Biosciences stock logo

Avidity Biosciences NASDAQ:RNA

$28.40 -0.63 (-2.17%)
As of 04:00 PM Eastern

Avidity Biosciences, Inc., a biopharmaceutical company, engages in the delivery of RNA therapeutics. It develops antibody oligonucleotide conjugates (AOC) that are designed to treat diseases previously untreatable with RNA therapeutics. The company's lead product candidate AOC 1001 for the treatment of myotonic dystrophy type 1, a rare monogenic muscle disease that is in phase 1/2 clinical trial. Its other products in pipeline include AOC 1044 for the treatment of duchenne muscular dystrophy, which is under phase 1/2 clinical development trial; and AOC 1020 to treat facioscapulohumeral muscular dystrophy that is in phase 1/2 clinical trial. The company is developing products for rare skeletal muscle and rare cardiac diseases. Avidity Biosciences, Inc. was incorporated in 2012 and is headquartered in San Diego, California.

SOPHiA GENETICS stock logo

SOPHiA GENETICS NASDAQ:SOPH

$3.10 +0.01 (+0.32%)
As of 04:00 PM Eastern

SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. The company offers SOPHiA DDM platform, a cloud-native software platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, applications, products, and services are used by hospitals, laboratories, and biopharmaceutical companies through its own sales force as well as distributors and industry collaborators in Switzerland, France, Italy, rest of Europe, North America, the United States, Latin America, and the Asia-pacific. SOPHiA GENETICS SA was incorporated in 2011 and is headquartered in Rolle, Switzerland.