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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
BCRX BioCryst Pharmaceuticals	$10.10 +1.4%	$9.71	$6.00 ▼ $11.31	$2.11B	1.11	3.01 million shs	5.71 million shs
BSTC BioSpecifics Technologies	$88.53	$88.47	$42.00 ▼ $89.15	$650.25M	0.24	61,105 shs	N/A
FOLD Amicus Therapeutics	$5.64 -1.6%	$6.39	$5.62 ▼ $12.65	$1.74B	0.54	3.08 million shs	17.42 million shs
LGND Ligand Pharmaceuticals	$114.07 -0.5%	$106.70	$77.53 ▼ $129.90	$2.20B	0.83	117,349 shs	259,225 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
BCRX BioCryst Pharmaceuticals	0.00%	-2.60%	-2.79%	+26.57%	+68.33%
BSTC BioSpecifics Technologies	0.00%	0.00%	0.00%	0.00%	0.00%
FOLD Amicus Therapeutics	0.00%	-6.47%	-9.90%	-37.40%	-42.27%
LGND Ligand Pharmaceuticals	0.00%	+1.40%	+12.62%	+5.47%	+41.63%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	Dividend Strength	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
BCRX BioCryst Pharmaceuticals	4.25 of 5 stars	4.4	1.0	0.0	4.2	2.2	1.7	0.6
BSTC BioSpecifics Technologies	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
FOLD Amicus Therapeutics	3.9951 of 5 stars	3.4	2.0	0.0	4.3	1.9	0.0	1.9
LGND Ligand Pharmaceuticals	4.4046 of 5 stars	3.5	0.0	0.0	4.4	2.6	3.3	1.9

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
BCRX BioCryst Pharmaceuticals	2.89	Moderate Buy	$16.56	63.92% Upside
BSTC BioSpecifics Technologies	0.00	N/A	N/A	N/A
FOLD Amicus Therapeutics	2.70	Moderate Buy	$16.22	187.63% Upside
LGND Ligand Pharmaceuticals	3.00	Buy	$146.14	28.12% Upside

Current Analyst Ratings Breakdown

Latest BSTC, LGND, BCRX, and FOLD Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
5/9/2025	LGND Ligand Pharmaceuticals	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$142.00 ➝ $145.00
5/7/2025	BCRX BioCryst Pharmaceuticals	Barclays Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Equal Weight ➝ Equal Weight	$8.00 ➝ $11.00
5/6/2025	BCRX BioCryst Pharmaceuticals	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform ➝ Outperform	$11.00 ➝ $13.00
5/6/2025	BCRX BioCryst Pharmaceuticals	JPMorgan Chase & Co. Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Overweight ➝ Overweight	$10.00 ➝ $13.00
5/6/2025	BCRX BioCryst Pharmaceuticals	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$15.00 ➝ $17.00
5/6/2025	BCRX BioCryst Pharmaceuticals	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$30.00 ➝ $30.00
5/2/2025	FOLD Amicus Therapeutics	UBS Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$21.00 ➝ $22.00
5/2/2025	FOLD Amicus Therapeutics	The Goldman Sachs Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Neutral ➝ Neutral	$12.00 ➝ $9.00
4/29/2025	BCRX BioCryst Pharmaceuticals	Cantor Fitzgerald Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Overweight	$20.00
4/11/2025	BCRX BioCryst Pharmaceuticals	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform ➝ Outperform	$11.00 ➝ $11.00
4/10/2025	BCRX BioCryst Pharmaceuticals	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$15.00 ➝ $15.00

(Data available from 6/22/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
BCRX BioCryst Pharmaceuticals	$450.71M	4.69	N/A	N/A	($2.30) per share	-4.39
BSTC BioSpecifics Technologies	$38.19M	17.03	$3.38 per share	26.18	$18.42 per share	4.81
FOLD Amicus Therapeutics	$528.29M	3.29	N/A	N/A	$0.65 per share	8.68
LGND Ligand Pharmaceuticals	$167.13M	13.17	$1.61 per share	70.99	$43.95 per share	2.60

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
BCRX BioCryst Pharmaceuticals	-$88.88M	-$0.26	N/A	N/A	2.28	-10.62%	N/A	-11.06%	8/4/2025 (Estimated)
BSTC BioSpecifics Technologies	$24.47M	$3.33	37.51	17.60	N/A	47.43%	14.81%	14.46%	N/A
FOLD Amicus Therapeutics	-$56.11M	-$0.09	N/A	13.12	N/A	-5.41%	4.67%	1.05%	8/14/2025 (Estimated)
LGND Ligand Pharmaceuticals	-$4.03M	-$7.12	N/A	30.75	N/A	-73.07%	-7.83%	-6.92%	8/5/2025 (Estimated)

Latest BSTC, LGND, BCRX, and FOLD Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue	Details
5/8/2025	Q1 2025	LGND Ligand Pharmaceuticals	$1.23	$1.33	+$0.10	-$2.21	$37.84 million	$45.33 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
BCRX BioCryst Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
BSTC BioSpecifics Technologies	N/A	N/A	N/A	N/A	N/A
FOLD Amicus Therapeutics	N/A	N/A	N/A	N/A	N/A
LGND Ligand Pharmaceuticals	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
BCRX BioCryst Pharmaceuticals	N/A	2.93	2.88
BSTC BioSpecifics Technologies	N/A	66.24	66.24
FOLD Amicus Therapeutics	2.02	3.34	2.47
LGND Ligand Pharmaceuticals	N/A	5.27	5.02

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
BCRX BioCryst Pharmaceuticals	85.88%
BSTC BioSpecifics Technologies	60.34%
FOLD Amicus Therapeutics	N/A
LGND Ligand Pharmaceuticals	91.28%

Insider Ownership

Company	Insider Ownership
BCRX BioCryst Pharmaceuticals	4.80%
BSTC BioSpecifics Technologies	15.70%
FOLD Amicus Therapeutics	2.20%
LGND Ligand Pharmaceuticals	7.00%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
BCRX BioCryst Pharmaceuticals	530	209.25 million	199.21 million	Optionable
BSTC BioSpecifics Technologies	7	7.35 million	N/A	Not Optionable
FOLD Amicus Therapeutics	480	307.93 million	301.16 million	Optionable
LGND Ligand Pharmaceuticals	80	19.29 million	17.94 million	Optionable

BSTC, LGND, BCRX, and FOLD Headlines

Recent News About These Companies

Advisor Resource Council Makes New $2.24 Million Investment in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 21 at 5:21 AM | marketbeat.com

SG Americas Securities LLC Acquires 5,201 Shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 21 at 3:34 AM | marketbeat.com

Chicago Capital LLC Has $58.30 Million Position in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 17, 2025 | marketbeat.com

Wealth Enhancement Advisory Services LLC Takes $286,000 Position in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 16, 2025 | marketbeat.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Insider Sells $57,270.00 in Stock

June 13, 2025 | insidertrades.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Receives $146.14 Consensus Target Price from Analysts

June 13, 2025 | americanbankingnews.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Insider Andrew Reardon Sells 500 Shares

June 12, 2025 | marketbeat.com

LGND Makes Bullish Cross Above Critical Moving Average

June 11, 2025 | nasdaq.com

Ligand Announces 2025 Investor Day in New York City

June 11, 2025 | globenewswire.com

GAMMA Investing LLC Purchases 61,996 Shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 10, 2025 | marketbeat.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Receives Consensus Rating of "Buy" from Brokerages

June 10, 2025 | marketbeat.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Shares Bought by Congress Asset Management Co.

June 7, 2025 | marketbeat.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Insider Andrew Reardon Sells 1,000 Shares

June 3, 2025 | marketbeat.com

Andrew Reardon Sells 1,000 Shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Stock

June 3, 2025 | insidertrades.com

UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Has $5.40 Million Stake in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 3, 2025 | marketbeat.com

Summit Global Investments Acquires 6,407 Shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

June 1, 2025 | marketbeat.com

Kings Path Partners LLC Reduces Stock Position in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

May 31, 2025 | marketbeat.com

Squarepoint Ops LLC Purchases Shares of 16,799 Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

May 31, 2025 | marketbeat.com

Bank of America Corp DE Purchases 2,533 Shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

May 25, 2025 | marketbeat.com

Castleark Management LLC Cuts Stock Position in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

May 23, 2025 | marketbeat.com

Ligand to Ring the Nasdaq Opening Bell on May 19, 2025

May 14, 2025 | globenewswire.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

BSTC, LGND, BCRX, and FOLD Company Descriptions

BioCryst Pharmaceuticals NASDAQ:BCRX

$10.10 +0.14 (+1.41%)

Closing price 06/20/2025 04:00 PM Eastern

Extended Trading

$9.99 -0.11 (-1.04%)

As of 06/20/2025 07:56 PM Eastern

BioCryst Pharmaceuticals, Inc., a biotechnology company, develops oral small-molecule and protein therapeutics to treat rare diseases. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX10013, an oral factor D inhibitor for complement-mediated diseases. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

BioSpecifics Technologies NASDAQ:BSTC

BioSpecifics Technologies Corp., a biopharmaceutical company, develops an injectable collagenase clostridium histolyticum for various indications in the United States and internationally. The company offers injectable collagenase for the treatment of Dupuytren's contracture and Peyronie's disease under the XIAFLEX and Xiapex brands. It also provides injectable collagenase to treat frozen shoulder, cellulite, canine lipoma, lateral hip fat, plantar fibromatosis, human lipoma, and uterine fibroids. The company has a development and license agreement with Endo Global Ventures. BioSpecifics Technologies Corp. was founded in 1957 and is headquartered in Wilmington, Delaware.

Amicus Therapeutics NASDAQ:FOLD

$5.64 -0.09 (-1.57%)

Closing price 06/20/2025 04:00 PM Eastern

Extended Trading

$5.64 +0.00 (+0.09%)

As of 06/20/2025 07:33 PM Eastern

Amicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant; and Pombiliti + Opfolda, for the treatment of late onset. It has collaboration and license agreements with the University of Pennsylvania to research and develop parvovirus gene therapy products; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Princeton, New Jersey.

Ligand Pharmaceuticals NASDAQ:LGND

$114.07 -0.57 (-0.50%)

Closing price 06/20/2025 04:00 PM Eastern

Extended Trading

$113.99 -0.08 (-0.07%)

As of 06/20/2025 04:16 PM Eastern

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and Evomela, which are used to treat multiple myeloma; Rylaze, a recombinant erwinia asparaginase for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; Filspari, a dual endothelin and angiotensin II receptor antagonist in development for rare kidney diseases and non-immunosuppressive treatment indicated for immunoglobulin A nephropathy; Teriparatide injection product for osteoporosis; Vaxneuvance for the prevention of invasive disease caused by streptococcus pneumoniae serotypes; and Pneumosil, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia among children. The company also offers TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and children aged 8 years and older with Stage 2 T1D; Nexterone, a captisol-enabled formulation of amiodarone; Zulresso, a captisol-enabled formulation of brexanolone for the treatment of postpartum depression; and Veklury, an antiviral treatment for moderate or severe COVID-19. In addition, it provides Noxafil-IV, a captisol-enabled formulation of posaconazole for IV use; Duavee for the treatment of post-menopausal symptoms in women; Exemptia for autoimmune diseases; Vivitra for breast cancer; and Bryxta and Zybev for various indications. The company has alliances, licenses, and other business relationships with Amgen, Merck, Pfizer, Jazz, Takeda, Gilead Sciences, and Baxter International. Further, it sells Captisol materials. Ligand Pharmaceuticals Incorporated was incorporated in 1987 and is based in Jupiter, Florida.

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Comparative Price Performance Over Time