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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ADXNNASDAQ:APRENASDAQ:CYCNNASDAQ:NOVN On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeADXNAddex Therapeutics$8.88+4.7%$8.08$6.51▼$13.27$8.98M1.6294,318 shs1,373 shsAPREAprea Therapeutics$1.64-7.5%$1.71$1.41▼$5.01$9.78M1.2223,276 shs30,352 shsCYCNCyclerion Therapeutics$2.95-6.3%$3.07$1.27▼$9.47$10.11M1.581.28 million shs17,413 shsNOVNNovan$0.00$0.08▼$3.33$2.64M-0.06602,421 shs7.19 million shs12 Stocks Corporate Insiders are AbandoningIf a company's CEO, COO, and CFO were all selling shares of their stock, would you want to know? MarketBeat just compiled its list of the twelve stocks that corporate insiders are abandoning. Complete the form below to see which companies made the list.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceADXNAddex Therapeutics-0.18%+7.70%+7.96%+12.18%+8.94%APREAprea Therapeutics-7.51%-13.49%+2.19%-31.59%-59.83%CYCNCyclerion Therapeutics-6.35%-5.14%-3.91%+7.27%+33.48%NOVNNovan0.00%0.00%0.00%0.00%0.00%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationADXNAddex Therapeutics2.3257 of 5 stars3.55.00.00.00.00.80.6APREAprea Therapeutics2.9118 of 5 stars3.53.00.00.01.12.51.3CYCNCyclerion Therapeutics0.7307 of 5 stars0.03.00.00.00.03.30.6NOVNNovanN/AN/AN/AN/AN/AN/AN/AN/ACompare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceADXNAddex Therapeutics 3.00Buy$30.00237.88% UpsideAPREAprea Therapeutics 3.00Buy$15.50848.01% UpsideCYCNCyclerion Therapeutics 0.00N/AN/AN/ANOVNNovan 0.00N/AN/AN/ACurrent Analyst Ratings BreakdownLatest NOVN, ADXN, APRE, and CYCN Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails3/25/2025APREAprea TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$11.00(Data available from 6/21/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookADXNAddex Therapeutics$460K20.46N/AN/A$10.37 per share0.86APREAprea Therapeutics$1.50M6.03N/AN/A$3.55 per share0.46CYCNCyclerion Therapeutics$2M4.73N/AN/A$3.27 per share0.90NOVNNovan$24.71M0.00N/AN/A$0.19 per share0.00Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateADXNAddex Therapeutics$8.02M-$0.34N/A∞N/A1,717.88%-61.65%-49.42%9/1/2025 (Estimated)APREAprea Therapeutics-$12.96M-$2.37N/AN/AN/A-1,095.02%-68.39%-55.74%8/11/2025 (Estimated)CYCNCyclerion Therapeutics-$3.06M-$1.16N/A∞N/AN/A-34.02%-30.68%8/6/2025 (Estimated)NOVNNovan-$31.31M-$1.32N/AN/AN/A-128.61%-700.28%-39.58%N/ALatest NOVN, ADXN, APRE, and CYCN EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/14/2025Q1 2025APREAprea Therapeutics-$0.6543-$0.66-$0.0057-$0.66N/A$0.16 million3/25/2025Q4 2024APREAprea Therapeutics-$0.69-$0.49+$0.20-$0.49$0.15 million$0.21 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthADXNAddex TherapeuticsN/AN/AN/AN/AN/AAPREAprea TherapeuticsN/AN/AN/AN/AN/ACYCNCyclerion TherapeuticsN/AN/AN/AN/AN/ANOVNNovanN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioADXNAddex TherapeuticsN/A4.424.42APREAprea TherapeuticsN/A5.905.90CYCNCyclerion TherapeuticsN/A4.214.21NOVNNovanN/A0.740.72Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipADXNAddex Therapeutics16.14%APREAprea Therapeutics34.19%CYCNCyclerion Therapeutics75.62%NOVNNovan14.51%Insider OwnershipCompanyInsider OwnershipADXNAddex Therapeutics15.00%APREAprea Therapeutics13.63%CYCNCyclerion Therapeutics34.30%NOVNNovan1.30%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableADXNAddex Therapeutics301.06 million901,000Not OptionableAPREAprea Therapeutics75.53 million4.78 millionNo DataCYCNCyclerion Therapeutics303.21 million2.11 millionNo DataNOVNNovan9028.02 million27.65 millionNot OptionableNOVN, ADXN, APRE, and CYCN HeadlinesRecent News About These CompaniesHow Novartis plans to thrive without competing directly with Eli Lilly in weight loss drug marketSeptember 18, 2024 | invezz.comNovartis AGFebruary 27, 2024 | wsj.comNovartis AG Registered SharesFebruary 16, 2024 | morningstar.comNovartis AG Registered Shares NOVNOctober 31, 2023 | morningstar.comNovan: Regulation Fd Disclosure, Financial Statements And ExhibitsOctober 25, 2023 | cbonds.comNovan reaches deals to sell assets in bankruptcy caseSeptember 8, 2023 | bizjournals.comFirm Retention Summary: NovanAugust 8, 2023 | msn.comNovan (NOVN) Price Target Increased by 43.52% to 15.81August 3, 2023 | msn.comNovan files patent for a composition and method of treating skinAugust 1, 2023 | pharmaceutical-technology.comInsider Sale Alert: Novan Inc. [NOVN] – Is it Time to sell?July 25, 2023 | knoxdaily.comNOVN short interest surges, indicating growing pessimism among investorsJuly 21, 2023 | knoxdaily.comNOVN stock rated an Overweight by Cantor FitzgeraldJuly 18, 2023 | knoxdaily.comNovan Shares Hit 52-Week Low After Bankruptcy DeclarationJuly 17, 2023 | marketwatch.comDurham biotech Novan to sell assets, files for bankruptcyJuly 17, 2023 | wraltechwire.comPotential Price Increase for Novan Inc. (NOVN) After Recent Insider ActivityJuly 11, 2023 | knoxdaily.comNovan Inc. [NOVN] Investment Guide: What You Need to KnowJuly 3, 2023 | knoxdaily.comCIMB appoints Novan Amirudin as CIMB Investment Bank CEOJune 16, 2023 | malaymail.comCIMB appoints Novan Amirudin as CEO of CIMB Investment BankJune 16, 2023 | thestar.com.myNovan Amirudin new CIMB Investment Bank CEOJune 16, 2023 | freemalaysiatoday.comDurham pharma Novan slashes 50% of workforce, mulls sale of assetsJune 1, 2023 | wraltechwire.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeNOVN, ADXN, APRE, and CYCN Company DescriptionsAddex Therapeutics NASDAQ:ADXN$8.88 +0.40 (+4.72%) As of 06/20/2025 04:00 PM Eastern This is a fair market value price provided by Polygon.io. Learn more.Addex Therapeutics Ltd discovers, develops, and commercializes small-molecule pharmaceutical products for central nervous system (CNS) disorders in Switzerland. The company focuses on the discovery of G-protein coupled receptors and enzymes. Its lead programs include Dipraglurant for the treatment of Parkinson's disease levodopa-induced dyskinesia and dystonia, and post-stroke/TBI recovery; ADX71149, a novel orally active metabotropic glutamate receptor subtype 2 positive allosteric modulator (mGlu2 PAM) for the treatment of epilepsy; and GABAB PAM for the treatment of pain, anxiety, overactive bladder, and addiction, as well as substance use disorder. Addex Therapeutics Ltd has license and collaboration agreement with Janssen Pharmaceuticals Inc. for the discovery, development, and commercialization of novel mGlu2 PAM compounds for the treatment of CNS and related diseases; license and research agreement with Indivior PLC discovery, development, and commercialization of novel GABAB PAM compounds for the treatment of addiction and other CNS diseases; and The CharcotMarieTooth Association to evaluate the role of GABAB PAM compounds in preclinical models of CMT1A. The company was formerly known as Addex Pharmaceuticals Ltd. Addex Therapeutics Ltd was founded in 2002 and is based in Geneva, Switzerland.Aprea Therapeutics NASDAQ:APRE$1.64 -0.13 (-7.17%) As of 06/20/2025 04:00 PM Eastern This is a fair market value price provided by Polygon.io. Learn more.Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidate is the ATRN-119 that is in Phase I clinical trials for treating advanced solid tumors. The company is also developing ATRN-1051 for the treatment of ovarian cancer; and APRE-DDRi for the treatment of advanced solid tumors. The company is headquartered in Doylestown, Pennsylvania.Cyclerion Therapeutics NASDAQ:CYCN$2.95 -0.20 (-6.35%) Closing price 06/20/2025 04:00 PM EasternExtended Trading$2.95 0.00 (0.00%) As of 06/20/2025 04:01 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Cyclerion Therapeutics, Inc., a biopharmaceutical company, develops treatments for serious diseases. It is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to out-license for cardiovascular diseases; and Praliciguat, a systemic sGC stimulator that is licensed to Akebia Therapeutics, Inc. for the treatment of rare kidney disease. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.Novan NASDAQ:NOVNNovan, Inc., a medical dermatology company, focuses on developing and commercializing therapeutic products for skin diseases. Its clinical stage dermatology drug candidates include SB204, a topical monotherapy for the treatment of acne vulgaris; SB206, a topical anti-viral gel for the treatment of viral skin infections; SB208, a topical broad-spectrum anti-fungal gel for the treatment of fungal infections of the skin and nails, including athlete's foot and fungal nail infections; and SB414, a topical cream-based gel product candidate for the treatment of inflammatory skin diseases. The company develops SB207, an anti-viral product candidate for the treatment of external genital warts; WH602, a nitric oxide-containing intravaginal gel to treat high-risk human papilloma virus (HPV); WH504, a non-gel formulation product candidate to treat high-risk HPV; and SB019 for the treatment of SARS-CoV-2. Novan, Inc. has a license agreement with Sato Pharmaceutical Co., Ltd.; and a strategic alliance with Orion Corporation. The company was incorporated in 2006 and is headquartered in Durham, North Carolina. 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