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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Curis, Inc. stock logo
CRIS
Curis
$2.16
-6.1%
$2.03
$1.02
$8.42
$24.06M3.6973,883 shs65,603 shs
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
$0.72
$0.72
$0.55
$1.45
$23.72M-0.57522,267 shsN/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
$0.18
$113.43
$34.53
$114.20
$6.94M2.05891,560 shsN/A
Passage Bio, Inc. stock logo
PASG
Passage Bio
$0.39
+0.1%
$0.37
$0.26
$1.33
$24.27M1.71361,254 shs51,602 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Curis, Inc. stock logo
CRIS
Curis
-6.09%-11.84%+12.50%-18.80%-72.31%
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
0.00%0.00%0.00%+2.94%-38.41%
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
0.00%0.00%0.00%0.00%0.00%
Passage Bio, Inc. stock logo
PASG
Passage Bio
+0.13%0.00%+29.90%-21.97%-59.06%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Curis, Inc. stock logo
CRIS
Curis
2.4023 of 5 stars
3.53.00.00.03.10.00.6
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
N/AN/AN/AN/AN/AN/AN/AN/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
N/AN/AN/AN/AN/AN/AN/AN/A
Passage Bio, Inc. stock logo
PASG
Passage Bio
2.0382 of 5 stars
3.52.00.00.00.01.71.3
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Curis, Inc. stock logo
CRIS
Curis
3.00
Buy$17.00687.04% Upside
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
2.33
Hold$0.9531.83% Upside
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
0.00
N/AN/AN/A
Passage Bio, Inc. stock logo
PASG
Passage Bio
3.00
Buy$7.501,818.16% Upside

Current Analyst Ratings Breakdown

Latest ONCE, CRIS, PASG, and CYTH Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
5/19/2025
Curis, Inc. stock logo
CRIS
Curis
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy$17.00
3/31/2025
Curis, Inc. stock logo
CRIS
Curis
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$20.00 ➝ $16.00
(Data available from 6/21/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Curis, Inc. stock logo
CRIS
Curis
$11.20M2.02N/AN/A($0.71) per share-3.04
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
$870.73K27.24N/AN/A$0.21 per share3.43
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
$64.72M0.11N/AN/A$13.15 per share0.01
Passage Bio, Inc. stock logo
PASG
Passage Bio
N/AN/AN/AN/A$0.99 per shareN/A
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Curis, Inc. stock logo
CRIS
Curis
-$43.39M-$6.23N/AN/AN/A-376.08%-923.37%-97.14%7/30/2025 (Estimated)
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
-$20.06M-$0.90N/AN/AN/A-2,847.19%N/A-307.16%N/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
-$78.82M-$2.11N/AN/AN/A-358.41%-59.10%-33.13%N/A
Passage Bio, Inc. stock logo
PASG
Passage Bio
-$64.77M-$1.02N/AN/AN/AN/A-93.59%-59.65%8/14/2025 (Estimated)

Latest ONCE, CRIS, PASG, and CYTH Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/13/2025Q1 2025
Passage Bio, Inc. stock logo
PASG
Passage Bio
-$0.24-$0.25-$0.01-$0.25N/AN/A
5/6/2025Q1 2025
Curis, Inc. stock logo
CRIS
Curis
-$1.14-$1.25-$0.11-$1.25$2.37 million$2.38 million
3/31/2025Q4 2024
Curis, Inc. stock logo
CRIS
Curis
-$1.36-$1.25+$0.11-$1.25$2.04 million$2.70 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Curis, Inc. stock logo
CRIS
Curis
N/AN/AN/AN/AN/A
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
N/AN/AN/AN/AN/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
N/AN/AN/AN/AN/A
Passage Bio, Inc. stock logo
PASG
Passage Bio
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Curis, Inc. stock logo
CRIS
Curis
N/A
1.23
1.23
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
N/A
0.17
0.16
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
0.35
4.67
4.35
Passage Bio, Inc. stock logo
PASG
Passage Bio
N/A
3.74
3.74

Institutional Ownership

CompanyInstitutional Ownership
Curis, Inc. stock logo
CRIS
Curis
29.97%
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
68.55%
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
88.37%
Passage Bio, Inc. stock logo
PASG
Passage Bio
53.48%

Insider Ownership

CompanyInsider Ownership
Curis, Inc. stock logo
CRIS
Curis
5.45%
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
29.78%
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
6.00%
Passage Bio, Inc. stock logo
PASG
Passage Bio
5.00%
CompanyEmployeesShares OutstandingFree FloatOptionable
Curis, Inc. stock logo
CRIS
Curis
6010.46 million9.89 millionNo Data
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
932.92 million23.12 millionNo Data
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
36838.52 millionN/ANo Data
Passage Bio, Inc. stock logo
PASG
Passage Bio
13062.15 million59.04 millionOptionable

Recent News About These Companies

Passage Bio price target lowered to $6 from $7 at Chardan
Passage Bio reports FY24 EPS ($1.07) vs ($1.86) last year

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

View All Headlines
Curis stock logo

Curis NASDAQ:CRIS

$2.16 -0.14 (-6.09%)
Closing price 06/20/2025 04:00 PM Eastern
Extended Trading
$2.14 -0.02 (-0.69%)
As of 06/20/2025 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Curis, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small molecule IRAK4 kinase inhibitor, which is in a Phase 1/2 open-label, single arm expansion trial in patients with relapsed or refractory, or R/R, AML and high-risk myelodysplastic syndromes. The company's pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma; CA-170, an oral, small molecule antagonist designated as CA-170 that selectively targets PD-L1 and VISTA; and CA-327, an oral, small molecule, TIM3/PD-L1, which is a molecule antagonist of PD-L1 and TIM3. It has collaboration agreement with Genentech Inc., or Genentech and F. Hoffmann-La Roche Ltd, or Roche, for the commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway antagonist for the treatment of advanced basal cell carcinoma, or BCC; Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology; and also licensed four programs under the Aurigene collaboration, including emavusertib. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.

Cyclo Therapeutics stock logo

Cyclo Therapeutics NASDAQ:CYTH

$0.72 0.00 (0.00%)
As of 03/26/2025

Cyclo Therapeutics, Inc., a clinical stage biotechnology company, engages in the development of cyclodextrin-based products for the treatment of neurodegenerative diseases. The company's lead drug candidate is Trappsol Cyclo (hydroxypropyl beta cyclodextrin), an orphan drug, which is in Phase III clinical trials for the treatment of Niemann-Pick Type C disease; and in Phase IIb clinical trials for the treatment of Alzheimer's disease. It also sells cyclodextrins and related products to the pharmaceutical, nutritional, and other industries, primarily for use in diagnostics and specialty drugs. The company was formerly known as CTD Holdings, Inc. and changed its name to Cyclo Therapeutics, Inc. in September 2019. Cyclo Therapeutics, Inc. was incorporated in 1990 and is headquartered in Gainesville, Florida.

Spark Therapeutics stock logo

Spark Therapeutics NASDAQ:ONCE

Spark Therapeutics, Inc. focuses on the development of gene therapy products for patients suffering from debilitating genetic diseases. Its products include LUXTURNA (voretigene neparvovec) for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy and viable retinal cells. The company's gene therapy product candidates comprise SPK-8011 and SPK-8016 for hemophilia; SPK-7001 for choroideremia; and SPK-9001 for hemophilia B. It is also developing other liver-directed gene therapies, including SPK-3006 for Pompe disease; and neurodegenerative disease product candidates to address Huntington's disease and others, as well as TPP1 deficiency, which is a form of Batten disease. The company's preclinical programs targets inherited retinal diseases, including Stargardt's disease. The company has collaboration agreement with Pfizer, Inc. for the development and commercialization of SPK-FIX product candidates in its gene therapy program for the treatment of hemophilia B. It also has licensing and commercialization agreement with Novartis to develop and commercialize voretigene neparvovec outside the United States. Spark Therapeutics, Inc. was founded in 2013 and is headquartered in Philadelphia, Pennsylvania.

Passage Bio stock logo

Passage Bio NASDAQ:PASG

$0.39 +0.00 (+0.13%)
Closing price 06/20/2025 04:00 PM Eastern
Extended Trading
$0.39 -0.01 (-1.28%)
As of 06/20/2025 07:05 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Passage Bio, Inc., a genetic medicines company, develops gene therapies for central nervous system diseases. It develops PBGM01, a functional GLB1 gene encoding ß-galactosidase for infantile GM1; PBFT02, a functional granulin (GRN) and gene encoding progranulin (PGRN) for the treatment of FTD caused by progranulin deficiency; and PBKR03, a functional GALC gene encoding the hydrolytic enzyme galactosylceramidase for infantile Krabbe disease. The company develops PBML04 for the treatment of metachromatic leukodystrophy; PBAL05 for the treatment of amyotrophic lateral sclerosis; and other program for huntington's disease. It has a strategic research collaboration with the Trustees of the University of Pennsylvania's Gene Therapy Program; and collaboration agreement, and a development services and clinical supply agreement with Catalent Maryland, Inc. Passage Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.