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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Curis, Inc. stock logo
CRIS
Curis
$2.77
-1.1%
$1.88
$1.02
$8.83
$28.98M3.6973,319 shs94,754 shs
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
$0.72
$0.72
$0.55
$1.45
$23.72M-0.57509,232 shsN/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
$0.18
$113.43
$34.53
$114.20
$6.94M2.05891,560 shsN/A
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
$3.05
-4.7%
$4.41
$2.67
$33.90
$17.66M0.67115,514 shs222,052 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Curis, Inc. stock logo
CRIS
Curis
+11.55%+18.64%+42.86%-1.41%-67.40%
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
0.00%0.00%0.00%+2.94%-41.89%
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
0.00%0.00%0.00%0.00%0.00%
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-10.11%-20.79%-4.19%-66.31%-89.84%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Curis, Inc. stock logo
CRIS
Curis
2.875 of 5 stars
3.53.00.00.03.60.01.3
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
N/AN/AN/AN/AN/AN/AN/AN/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
N/AN/AN/AN/AN/AN/AN/AN/A
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
4.3623 of 5 stars
3.52.00.04.62.63.30.6
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Curis, Inc. stock logo
CRIS
Curis
3.00
Buy$17.00513.72% Upside
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
2.33
Hold$0.9531.83% Upside
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
0.00
N/AN/AN/A
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
3.00
Buy$72.332,271.58% Upside

Current Analyst Ratings Breakdown

Latest ONCE, CRIS, XFOR, and CYTH Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
5/19/2025
Curis, Inc. stock logo
CRIS
Curis
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy$17.00
5/2/2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$1.50 ➝ $7.00
3/31/2025
Curis, Inc. stock logo
CRIS
Curis
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$20.00 ➝ $16.00
3/27/2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$45.00 ➝ $45.00
3/26/2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOverweight ➝ Overweight$90.00 ➝ $90.00
(Data available from 6/12/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Curis, Inc. stock logo
CRIS
Curis
$11.20M2.59N/AN/A$3.34 per share0.83
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
$870.73K27.24N/AN/A$0.21 per share3.43
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
$64.72M0.11N/AN/A$13.15 per share0.01
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
$31.36M0.56N/AN/A$0.31 per share9.84
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Curis, Inc. stock logo
CRIS
Curis
-$47.41M-$6.23N/AN/AN/A-443.35%-923.37%-78.35%7/30/2025 (Estimated)
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
-$20.06M-$0.90N/AN/AN/A-2,847.19%N/A-307.16%N/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
-$78.82M-$2.11N/AN/AN/A-358.41%-59.10%-33.13%N/A
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-$101.17M$2.14N/AN/AN/AN/A-236.19%-75.14%8/6/2025 (Estimated)

Latest ONCE, CRIS, XFOR, and CYTH Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/6/2025Q1 2025
Curis, Inc. stock logo
CRIS
Curis
-$1.14-$1.25-$0.11-$1.25$2.37 million$2.38 million
5/1/2025Q1 2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-$4.13$0.04+$4.17$0.04$7.03 million$28.81 million
3/31/2025Q4 2024
Curis, Inc. stock logo
CRIS
Curis
-$1.36-$1.25+$0.11-$1.25$2.04 million$2.70 million
3/25/2025Q4 2024
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-$5.10-$6.00-$0.90-$0.20$1.07 million$1.43 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Curis, Inc. stock logo
CRIS
Curis
N/AN/AN/AN/AN/A
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
N/AN/AN/AN/AN/A
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
N/AN/AN/AN/AN/A
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Curis, Inc. stock logo
CRIS
Curis
N/A
1.22
1.22
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
N/A
0.17
0.16
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
0.35
4.67
4.35
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
1.26
4.89
4.80

Institutional Ownership

CompanyInstitutional Ownership
Curis, Inc. stock logo
CRIS
Curis
29.97%
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
68.55%
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
88.37%
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
72.03%

Insider Ownership

CompanyInsider Ownership
Curis, Inc. stock logo
CRIS
Curis
5.70%
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
29.78%
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
6.00%
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
2.37%
CompanyEmployeesShares OutstandingFree FloatOptionable
Curis, Inc. stock logo
CRIS
Curis
6010.46 million7.98 millionNo Data
Cyclo Therapeutics, Inc. stock logo
CYTH
Cyclo Therapeutics
932.92 million23.12 millionNo Data
Spark Therapeutics Inc stock logo
ONCE
Spark Therapeutics
36838.52 millionN/ANo Data
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
805.79 million167.78 millionOptionable

Recent News About These Companies

X4 Pharmaceuticals Analyst Ratings
Earnings Preview For X4 Pharmaceuticals
Why X4 Pharmaceuticals, Inc. (XFOR) is Surging in 2025
X4 Pharmaceuticals trading halted, news pending
X4 Pharmaceuticals announces 1-for-30 reverse stock split

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

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Curis stock logo

Curis NASDAQ:CRIS

$2.77 -0.03 (-1.07%)
As of 04:00 PM Eastern

Curis, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small molecule IRAK4 kinase inhibitor, which is in a Phase 1/2 open-label, single arm expansion trial in patients with relapsed or refractory, or R/R, AML and high-risk myelodysplastic syndromes. The company's pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma; CA-170, an oral, small molecule antagonist designated as CA-170 that selectively targets PD-L1 and VISTA; and CA-327, an oral, small molecule, TIM3/PD-L1, which is a molecule antagonist of PD-L1 and TIM3. It has collaboration agreement with Genentech Inc., or Genentech and F. Hoffmann-La Roche Ltd, or Roche, for the commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway antagonist for the treatment of advanced basal cell carcinoma, or BCC; Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology; and also licensed four programs under the Aurigene collaboration, including emavusertib. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.

Cyclo Therapeutics stock logo

Cyclo Therapeutics NASDAQ:CYTH

$0.72 0.00 (0.00%)
As of 03/26/2025

Cyclo Therapeutics, Inc., a clinical stage biotechnology company, engages in the development of cyclodextrin-based products for the treatment of neurodegenerative diseases. The company's lead drug candidate is Trappsol Cyclo (hydroxypropyl beta cyclodextrin), an orphan drug, which is in Phase III clinical trials for the treatment of Niemann-Pick Type C disease; and in Phase IIb clinical trials for the treatment of Alzheimer's disease. It also sells cyclodextrins and related products to the pharmaceutical, nutritional, and other industries, primarily for use in diagnostics and specialty drugs. The company was formerly known as CTD Holdings, Inc. and changed its name to Cyclo Therapeutics, Inc. in September 2019. Cyclo Therapeutics, Inc. was incorporated in 1990 and is headquartered in Gainesville, Florida.

Spark Therapeutics stock logo

Spark Therapeutics NASDAQ:ONCE

Spark Therapeutics, Inc. focuses on the development of gene therapy products for patients suffering from debilitating genetic diseases. Its products include LUXTURNA (voretigene neparvovec) for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy and viable retinal cells. The company's gene therapy product candidates comprise SPK-8011 and SPK-8016 for hemophilia; SPK-7001 for choroideremia; and SPK-9001 for hemophilia B. It is also developing other liver-directed gene therapies, including SPK-3006 for Pompe disease; and neurodegenerative disease product candidates to address Huntington's disease and others, as well as TPP1 deficiency, which is a form of Batten disease. The company's preclinical programs targets inherited retinal diseases, including Stargardt's disease. The company has collaboration agreement with Pfizer, Inc. for the development and commercialization of SPK-FIX product candidates in its gene therapy program for the treatment of hemophilia B. It also has licensing and commercialization agreement with Novartis to develop and commercialize voretigene neparvovec outside the United States. Spark Therapeutics, Inc. was founded in 2013 and is headquartered in Philadelphia, Pennsylvania.

X4 Pharmaceuticals stock logo

X4 Pharmaceuticals NASDAQ:XFOR

$3.05 -0.15 (-4.69%)
As of 04:00 PM Eastern

X4 Pharmaceuticals, Inc., a late-stage clinical biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is mavorixafor, a small molecule inhibitor of the chemokine receptor C-X-C chemokine receptor type 4 (CXCR4), which is in Phase III clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome; and Phase II clinical trial to treat congenital, idiopathic, or cyclic neutropenia. The company is also developing X4P-003, a CXCR4 antagonist for the treatment of CXCR4 dependent disorders and primary immunodeficiencies; and X4P-002, a CXCR4 antagonist for the treatment of blood-brain barrier diseases. It has a license agreement with Abbisko Therapeutics Co Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications. The company is headquartered in Boston, Massachusetts.