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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
LENZ LENZ Therapeutics	$34.69 +1.3%	$29.45	$16.54 ▼ $38.93	$976.39M	0.42	195,349 shs	494,289 shs
PRQR ProQR Therapeutics	$2.32 -1.7%	$1.84	$1.07 ▼ $4.62	$244.09M	0.36	657,904 shs	186,473 shs
RCUS Arcus Biosciences	$9.35 -2.0%	$8.87	$6.50 ▼ $18.98	$990.07M	0.8	883,406 shs	545,958 shs
ZYME Zymeworks	$13.34 -2.3%	$12.26	$9.03 ▼ $17.70	$929.57M	1.19	581,139 shs	363,270 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
LENZ LENZ Therapeutics	-1.61%	+5.30%	+22.01%	+69.10%	+83.60%
PRQR ProQR Therapeutics	+2.61%	+10.13%	+33.33%	+110.71%	+38.01%
RCUS Arcus Biosciences	+2.09%	+12.29%	-5.28%	+17.56%	-31.81%
ZYME Zymeworks	+0.66%	+6.43%	+4.51%	+28.50%	+47.84%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	News and Social Media Sentiment	Company Ownership
LENZ LENZ Therapeutics	1.0692 of 5 stars	3.6	0.0	0.6	0.8
PRQR ProQR Therapeutics	2.04 of 5 stars	3.6	3.0	2.4	0.0
RCUS Arcus Biosciences	2.9444 of 5 stars	4.4	3.0	1.2	1.7
ZYME Zymeworks	2.1737 of 5 stars	3.5	1.0	1.8	3.3

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
LENZ LENZ Therapeutics	3.17	Buy	$46.60	31.81% Upside
PRQR ProQR Therapeutics	3.13	Buy	$8.00	241.15% Upside
RCUS Arcus Biosciences	2.89	Moderate Buy	$21.29	126.93% Upside
ZYME Zymeworks	2.90	Moderate Buy	$21.00	55.61% Upside

Current Analyst Ratings Breakdown

Latest PRQR, LENZ, ZYME, and RCUS Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
7/3/2025	ZYME Zymeworks	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Neutral ➝ Neutral	$13.00
6/27/2025	PRQR ProQR Therapeutics	Cantor Fitzgerald Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Overweight ➝ Overweight	$8.00
6/27/2025	PRQR ProQR Therapeutics	JMP Securities Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Market Outperform ➝ Market Outperform	$8.00
5/20/2025	ZYME Zymeworks	TD Securities Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy
5/20/2025	ZYME Zymeworks	TD Cowen Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy
5/13/2025	PRQR ProQR Therapeutics	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Outperform ➝ Outperform	$15.00 ➝ $9.00
5/9/2025	RCUS Arcus Biosciences	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Overweight ➝ Overweight	$24.00 ➝ $22.00
5/8/2025	LENZ LENZ Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$38.00 ➝ $38.00
5/8/2025	RCUS Arcus Biosciences	The Goldman Sachs Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Neutral ➝ Neutral	$15.00 ➝ $13.00
5/7/2025	RCUS Arcus Biosciences	Wedbush Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform	$33.00
5/7/2025	RCUS Arcus Biosciences	Wells Fargo & Company Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Overweight ➝ Overweight	$29.00 ➝ $26.00

(Data available from 7/11/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
LENZ LENZ Therapeutics	N/A	N/A	N/A	N/A	$7.42 per share	N/A
PRQR ProQR Therapeutics	$20.46M	12.06	N/A	N/A	$0.91 per share	2.58
RCUS Arcus Biosciences	$258M	3.85	N/A	N/A	$5.30 per share	1.77
ZYME Zymeworks	$93.38M	10.07	N/A	N/A	$6.63 per share	2.04

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
LENZ LENZ Therapeutics	-$49.77M	-$1.77	N/A	N/A	N/A	N/A	-23.74%	-22.65%	8/13/2025 (Estimated)
PRQR ProQR Therapeutics	-$30.04M	-$0.35	N/A	N/A	N/A	-157.04%	-53.49%	-22.07%	8/4/2025 (Estimated)
RCUS Arcus Biosciences	-$283M	-$4.19	N/A	N/A	N/A	-258.94%	-70.58%	-32.97%	8/4/2025 (Estimated)
ZYME Zymeworks	-$118.67M	-$1.49	N/A	N/A	N/A	-182.75%	-23.00%	-18.04%	7/30/2025 (Estimated)

Latest PRQR, LENZ, ZYME, and RCUS Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/7/2025	N/A	ZYME Zymeworks	-$0.52	N/A	N/A	N/A	$17.18 million	N/A
5/8/2025	Q1 2025	PRQR ProQR Therapeutics	-$0.09	-$0.1082	-$0.0182	-$0.11	$4.90 million	$4.89 million
5/8/2025	N/A	ZYME Zymeworks	-$0.45	-$0.30	+$0.15	N/A	$20.65 million	$27.11 million
5/7/2025	Q1 2025	LENZ LENZ Therapeutics	-$0.55	-$0.53	+$0.02	-$0.53	N/A	N/A
5/6/2025	Q1 2025	RCUS Arcus Biosciences	-$1.02	-$1.14	-$0.12	-$1.14	$38.61 million	$28.00 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
LENZ LENZ Therapeutics	N/A	N/A	N/A	N/A	N/A
PRQR ProQR Therapeutics	N/A	N/A	N/A	N/A	N/A
RCUS Arcus Biosciences	N/A	N/A	N/A	N/A	N/A
ZYME Zymeworks	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
LENZ LENZ Therapeutics	N/A	23.09	23.09
PRQR ProQR Therapeutics	N/A	4.10	4.10
RCUS Arcus Biosciences	0.09	5.37	5.37
ZYME Zymeworks	N/A	4.10	4.10

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
LENZ LENZ Therapeutics	54.32%
PRQR ProQR Therapeutics	32.65%
RCUS Arcus Biosciences	92.89%
ZYME Zymeworks	92.89%

Insider Ownership

Company	Insider Ownership
LENZ LENZ Therapeutics	6.90%
PRQR ProQR Therapeutics	8.40%
RCUS Arcus Biosciences	9.60%
ZYME Zymeworks	1.92%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
LENZ LENZ Therapeutics	110	28.15 million	26.20 million	N/A
PRQR ProQR Therapeutics	180	105.21 million	96.38 million	Optionable
RCUS Arcus Biosciences	500	105.89 million	95.72 million	Optionable
ZYME Zymeworks	460	69.68 million	67.56 million	Optionable

PRQR, LENZ, ZYME, and RCUS Headlines

Recent News About These Companies

ZYME | Zymeworks Inc. Annual Cash Flow Statement | MarketWatch

July 11 at 11:23 AM | marketwatch.com

Bispecific Antibody Clinical Trial Pipeline Gains Momentum: 180+ Companies Lead the Charge in Pioneering New Treatments | DelveInsight

July 9 at 2:55 AM | finance.yahoo.com

Zymeworks (NYSE:ZYME) Receives "Neutral" Rating from HC Wainwright

July 5, 2025 | americanbankingnews.com

Zymeworks (NYSE:ZYME) Given "Neutral" Rating at HC Wainwright

July 3, 2025 | marketbeat.com

Zymeworks Amends Warrant Agreement with EcoR1 Capital

June 27, 2025 | tipranks.com

ZYME - Zymeworks Inc Registered Shs Dividends - Morningstar

June 27, 2025 | morningstar.comM

Companies Like Zymeworks (NASDAQ:ZYME) Are In A Position To Invest In Growth

June 25, 2025 | finance.yahoo.com

Zymeworks Inc. (NYSE:ZYME) Given Average Recommendation of "Moderate Buy" by Brokerages

June 21, 2025 | marketbeat.com

All You Need to Know About Zymeworks (ZYME) Rating Upgrade to Buy

June 20, 2025 | zacks.com

Rhumbline Advisers Has $985,000 Stock Position in Zymeworks Inc. (NYSE:ZYME)

June 20, 2025 | marketbeat.com

Duncan Williams Asset Management LLC Buys Shares of 22,095 Zymeworks Inc. (NYSE:ZYME)

June 19, 2025 | marketbeat.com

Zymeworks Inc (NASDAQ:ZYME) Valuation Biotech Sector Trends S&P 500

June 18, 2025 | kalkinemedia.comK

SG Americas Securities LLC Raises Position in Zymeworks Inc. (NYSE:ZYME)

June 17, 2025 | marketbeat.com

Assenagon Asset Management S.A. Sells 147,184 Shares of Zymeworks Inc. (NYSE:ZYME)

June 15, 2025 | marketbeat.com

Zymeworks (NYSE:ZYME) Shares Gap Down - Time to Sell?

June 13, 2025 | marketbeat.com

Zymeworks: Early-Stage Biotech Feel Despite Zanidatamab Advancements (Downgrade)

June 12, 2025 | seekingalpha.com

Bank of America Corp DE Sells 38,030 Shares of Zymeworks Inc. (NYSE:ZYME)

June 12, 2025 | marketbeat.com

Wall Street Analysts See a 76.74% Upside in Zymeworks (ZYME): Can the Stock Really Move This High?

June 4, 2025 | zacks.com

Zymeworks’ zanidatamab gains approval in China for biliary tract cancer

June 2, 2025 | msn.com

Roche’s 96-week data for multiple sclerosis drug; ZymeWorks claims $20M milestone

May 30, 2025 | endpts.comE

China's NMPA Approves Zymeworks' Ziihera for HER2-High Biliary Tract Cancer

May 30, 2025 | precisionmedicineonline.comP

New MarketBeat Followers Over Time

Media Sentiment Over Time

PRQR, LENZ, ZYME, and RCUS Company Descriptions

LENZ Therapeutics NASDAQ:LENZ

$34.69 +0.43 (+1.26%)

Closing price 04:00 PM Eastern

Extended Trading

$34.82 +0.13 (+0.37%)

As of 04:51 PM Eastern

LENZ Therapeutics, Inc., a biopharmaceutical company, focuses on developing and commercializing therapies to improve vision in the United States. Its product candidates include LNZ100 and LNZ101 which are in Phase III clinical trials for the treatment of presbyopia. The company is headquartered in Del Mar, California.

ProQR Therapeutics NASDAQ:PRQR

$2.32 -0.04 (-1.69%)

Closing price 04:00 PM Eastern

Extended Trading

$2.42 +0.10 (+4.27%)

As of 05:50 PM Eastern

ProQR Therapeutics N.V., a biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company's products pipeline includes AX-0810 for cholestatic diseases targeting Na-taurocholate cotransporting polypeptide (NTCP); and AX-1412 for cardiovascular diseases (CVDs) targeting Beta-1,4-galactosyltransferase 1 (B4GALT1). It also develops various other early-stage research programs, including AX-1005 for undisclosed targets in CVDs; AX-2402, which focuses on Rett syndrome; AX-2911 for nonalcoholic steatohepatitis (NASH); AX-0601 for obesity and Type 2 diabetes; and AX-9115 for rare metabolic condition, as well as various other targets. In addition, the company develops Axiomer RNA base-editing platform technology. It has a license agreement with Radboud University Medical Center; Inserm Transfert SA; Ionis Pharmaceuticals, Inc.; Vico Therapeutics B.V.; University of Rochester; and Leiden University Medical Center, as well as license and research collaboration with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.

Arcus Biosciences NYSE:RCUS

$9.35 -0.19 (-1.99%)

Closing price 03:59 PM Eastern

Extended Trading

$9.24 -0.12 (-1.23%)

As of 04:29 PM Eastern

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. The company's pipeline products include Domvanalimab, an anti-TIGIT antibody, which is in Phase 2 and Phase 3 clinical trial; and AB308, an investigational anti-TIGIT monoclonal antibody, which is in Phase 1b clinical trial to study people with advanced solid and hematologic malignancies. It also develops Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in Phase 2 clinical trial; Quemliclustat, a small-molecule CD73 inhibitor, which is Phase 1b and Phase 2 clinical trial; Zimberelimab, an anti-PD-1 antibody, which is in Phase 2 clinical trial for metastatic cell lung cancer and monotherapy; and AB521, an oral and small-molecule inhibitor of HIF-2a, which is in Phase 1 clinical trial for the treatment of Von Hippel-Lindau disease. In addition, the company's preclinical pipeline products include AB598, a CD39 antibody; and AB801, a small molecule Axl inhibitor. It has a clinical collaboration with AstraZeneca to evaluate domvanalimab in combination with durvalumab in a registrational phase 3 clinical trial in patients with unresectable Stage 3 NSCLC; and BVF Partners L.P. to support the discovery and development of compounds for the treatment of inflammatory diseases. Arcus Biosciences, Inc. was incorporated in 2015 and is headquartered in Hayward, California.

Zymeworks NYSE:ZYME

$13.34 -0.32 (-2.34%)

Closing price 04:00 PM Eastern

Extended Trading

$13.34 0.00 (0.00%)

As of 04:29 PM Eastern

Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a human epidermal growth factor receptor 2 (HER2) that is in Phase 1, Phase 2, and Phase 3 clinical trials, including certain ongoing pivotal clinical trials; and zanidatamab zovodotin, a HER2 -targeted antibody-drug conjugate that is in Phase 2 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. It also develops a pipeline of preclinical product candidates and discovery-stage programs in oncology, including immuno-oncology agents and other therapeutic areas. Zymeworks Inc. has strategic partnerships and collaborations with BeiGene, Ltd.; Celgene Corporation; Celgene Alpine Investment Co. LLC; GlaxoSmithKline Intellectual Property Development Limited; Daiichi Sankyo Co., Ltd.; Janssen Biotech, Inc.; LEO Pharma A/S; Iconic Therapeutics, Inc.; Merck Sharp & Dohme Research GmbH; and Atreca, Inc. Zymeworks Inc. was incorporated in 2003 and is based in Middletown, Delaware.

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Comparative Price Performance Over Time