S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
$19.87
+0.2%
$23.25
$13.36
$27.50
$531.72M-0.3313,083 shs288,943 shs
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
$18.70
+5.9%
$21.08
$15.25
$29.30
$557.07M1.58,074 shs4,016 shs
Organigram Holdings Inc. stock logo
OGI
Organigram
$1.89
+1.1%
$2.09
$0.97
$2.91
$195.05M1.091.38 million shs1.42 million shs
Provention Bio, Inc. stock logo
PRVB
Provention Bio
$24.98
+3.1%
$24.58
$3.18
$25.00
$2.37B2.472.28 million shs9.12 million shs
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
$1.08
+2.9%
$1.34
$0.71
$1.96
$189.43M0.951.24 million shs812,732 shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
-7.64%-19.81%-14.78%-15.51%-13.33%
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
-5.82%-14.03%-18.29%-24.86%-30.24%
Organigram Holdings Inc. stock logo
OGI
Organigram
+2.19%-8.78%-15.77%+0.54%-14.77%
Provention Bio, Inc. stock logo
PRVB
Provention Bio
0.00%0.00%0.00%0.00%+2.21%
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
-5.41%-14.63%-23.36%-22.79%-16.67%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
2.5377 of 5 stars
4.40.00.00.02.62.50.6
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
2.997 of 5 stars
3.35.00.00.02.60.01.9
Organigram Holdings Inc. stock logo
OGI
Organigram
0.2232 of 5 stars
0.02.00.00.02.50.01.3
Provention Bio, Inc. stock logo
PRVB
Provention Bio
N/AN/AN/AN/AN/AN/AN/AN/A
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
1.7816 of 5 stars
3.32.00.00.02.81.70.6

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
2.80
Moderate Buy$46.22132.62% Upside
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
2.50
Moderate Buy$34.0081.82% Upside
Organigram Holdings Inc. stock logo
OGI
Organigram
3.00
BuyN/AN/A
Provention Bio, Inc. stock logo
PRVB
Provention Bio
N/AN/AN/AN/A
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
2.50
Moderate Buy$5.81438.19% Upside

Current Analyst Ratings

Latest OGI, ANAB, PRVB, RIGL, and CALT Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/16/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Leerink Partnrs
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform
4/16/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
SVB Leerink
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$47.00
4/15/2024
Organigram Holdings Inc. stock logo
OGI
Organigram
Alliance Global Partners
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeNeutral ➝ Buy
4/11/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Wells Fargo & Company
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOverweight$56.00
4/1/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
JPMorgan Chase & Co.
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetNeutral ➝ Neutral$30.00 ➝ $28.00
3/12/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeNeutral ➝ Outperform$20.00 ➝ $34.00
3/7/2024
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
Citigroup
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$3.00 ➝ $4.00
3/6/2024
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetNeutral ➝ Neutral$2.00 ➝ $3.00
3/6/2024
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$15.00
3/6/2024
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
B. Riley
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingNeutral ➝ Neutral$1.25
2/26/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
BTIG Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageBuy$55.00
(Data available from 4/19/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
$17.16M30.99N/AN/A$3.32 per share5.98
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
$113.78M4.90N/AN/A$1.06 per share17.64
Organigram Holdings Inc. stock logo
OGI
Organigram
$120.01M1.63N/AN/A$2.48 per share0.76
Provention Bio, Inc. stock logo
PRVB
Provention Bio
$12.90M183.54N/AN/A$1.40 per share17.84
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
$116.88M1.62N/AN/A($0.16) per share-6.75

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
-$163.62M-$6.08N/AN/AN/A-953.66%-119.42%-32.58%5/9/2024 (Estimated)
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
-$43.96M-$1.64N/A5.42N/A-38.72%-104.47%-26.75%5/21/2024 (Estimated)
Organigram Holdings Inc. stock logo
OGI
Organigram
-$184.34M-$0.80N/AN/AN/A-173.48%-30.94%-27.70%4/23/2024 (Estimated)
Provention Bio, Inc. stock logo
PRVB
Provention Bio
-$113.57M-$1.53N/AN/AN/A-880.69%-103.36%-69.08%N/A
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
-$25.09M-$0.15N/A21.60N/A-21.47%N/A-21.21%5/7/2024 (Estimated)

Latest OGI, ANAB, PRVB, RIGL, and CALT Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
3/11/2024Q4 2023
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
-$1.74-$1.59+$0.15-$1.59$3.28 million$9.01 million
2/21/202412/31/2023
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
-$0.09-$0.07+$0.02-$0.06$36.24 million$42.45 million    
2/13/2024Q1 2024
Organigram Holdings Inc. stock logo
OGI
Organigram
-$0.10-$0.14-$0.04-$0.14$28.61 million$26.78 million

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
N/AN/AN/AN/AN/A
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
N/AN/AN/AN/AN/A
Organigram Holdings Inc. stock logo
OGI
Organigram
N/AN/AN/AN/AN/A
Provention Bio, Inc. stock logo
PRVB
Provention Bio
N/AN/AN/AN/AN/A
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
N/AN/AN/AN/AN/A

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
N/A
10.87
10.87
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
2.89
3.13
3.08
Organigram Holdings Inc. stock logo
OGI
Organigram
N/A
4.28
2.11
Provention Bio, Inc. stock logo
PRVB
Provention Bio
0.19
1.93
1.92
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
N/A
1.86
1.76

Ownership

Institutional Ownership

CompanyInstitutional Ownership
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
N/A
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
2.83%
Organigram Holdings Inc. stock logo
OGI
Organigram
34.63%
Provention Bio, Inc. stock logo
PRVB
Provention Bio
37.39%
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
66.23%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
11726.76 million17.26 millionOptionable
Calliditas Therapeutics AB (publ) stock logo
CALT
Calliditas Therapeutics AB (publ)
19229.79 million29.14 millionOptionable
Organigram Holdings Inc. stock logo
OGI
Organigram
984103.20 million103.11 millionOptionable
Provention Bio, Inc. stock logo
PRVB
Provention Bio
8294.78 million82.37 millionNot Optionable
Rigel Pharmaceuticals, Inc. stock logo
RIGL
Rigel Pharmaceuticals
147175.40 million160.67 millionOptionable

OGI, ANAB, PRVB, RIGL, and CALT Headlines

SourceHeadline
Rigel Pharmaceuticals (NASDAQ:RIGL) Shares Cross Above 200-Day Moving Average of $1.19Rigel Pharmaceuticals (NASDAQ:RIGL) Shares Cross Above 200-Day Moving Average of $1.19
americanbankingnews.com - April 12 at 2:22 AM
Rigel Announces Inducement Grants under NASDAQ Listing Rule 5635(c)(4)Rigel Announces Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
prnewswire.com - April 10 at 4:30 PM
Rigel Announces Publication of Data on REZLIDHIA® (Olutasidenib) in Post-Venetoclax Patients with Mutant IDH1 AML in Leukemia & LymphomaRigel Announces Publication of Data on REZLIDHIA® (Olutasidenib) in Post-Venetoclax Patients with Mutant IDH1 AML in Leukemia & Lymphoma
prnewswire.com - April 4 at 8:05 AM
Assenagon Asset Management S.A. Has $2.89 Million Stake in Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL)Assenagon Asset Management S.A. Has $2.89 Million Stake in Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL)
marketbeat.com - April 3 at 4:36 AM
Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL) Sees Large Growth in Short InterestRigel Pharmaceuticals, Inc. (NASDAQ:RIGL) Sees Large Growth in Short Interest
marketbeat.com - April 1 at 8:31 AM
Rigel Pharmaceuticals (NASDAQ:RIGL) Raised to "Buy" at StockNews.comRigel Pharmaceuticals (NASDAQ:RIGL) Raised to "Buy" at StockNews.com
marketbeat.com - March 27 at 11:16 PM
RIGL Apr 2024 3.000 callRIGL Apr 2024 3.000 call
finance.yahoo.com - March 16 at 7:34 AM
Rigel Pharmaceuticals, Inc.: Rigel Pharmaceuticals Announces Appointment of Lisa Rojkjaer, M.D. as Chief Medical OfficerRigel Pharmaceuticals, Inc.: Rigel Pharmaceuticals Announces Appointment of Lisa Rojkjaer, M.D. as Chief Medical Officer
finanznachrichten.de - March 12 at 12:09 PM
Rigel Pharma Names Rojkjaer EVP, Chief Medical OfficerRigel Pharma Names Rojkjaer EVP, Chief Medical Officer
markets.businessinsider.com - March 12 at 12:09 PM
Rigel Pharmaceuticals Announces Appointment of Lisa Rojkjaer, M.D. as Chief Medical OfficerRigel Pharmaceuticals Announces Appointment of Lisa Rojkjaer, M.D. as Chief Medical Officer
prnewswire.com - March 12 at 8:05 AM
Rigel Pharmaceuticals Inc (RIGL) Reports Growth in 2023 Sales, Despite Net Loss for the YearRigel Pharmaceuticals Inc (RIGL) Reports Growth in 2023 Sales, Despite Net Loss for the Year
finance.yahoo.com - March 7 at 6:17 PM
Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL) Q4 2023 Earnings Call TranscriptRigel Pharmaceuticals, Inc. (NASDAQ:RIGL) Q4 2023 Earnings Call Transcript
insidermonkey.com - March 7 at 1:01 PM
Rigel Pharmaceuticals Inc.Rigel Pharmaceuticals Inc.
barrons.com - March 6 at 10:15 PM
Rigel Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business UpdateRigel Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update
stockhouse.com - March 6 at 5:14 PM
Rigel Pharmaceuticals: Q4 Earnings InsightsRigel Pharmaceuticals: Q4 Earnings Insights
benzinga.com - March 6 at 5:14 PM
Rigel Pharmaceuticals Inc. Q4 Earnings SummaryRigel Pharmaceuticals Inc. Q4 Earnings Summary
markets.businessinsider.com - March 6 at 5:14 PM
Rigel Pharmaceuticals GAAP EPS of $0.00 beats by $0.02, revenue of $35.8M beats by $2.39MRigel Pharmaceuticals GAAP EPS of $0.00 beats by $0.02, revenue of $35.8M beats by $2.39M
msn.com - March 6 at 5:14 PM
Owning 47% shares,institutional owners seem interested in Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL),Owning 47% shares,institutional owners seem interested in Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL),
finance.yahoo.com - March 6 at 5:14 PM
Q4 2023 Rigel Pharmaceuticals Inc Earnings CallQ4 2023 Rigel Pharmaceuticals Inc Earnings Call
finance.yahoo.com - March 6 at 5:14 PM
Q4 2023 Rigel Pharmaceuticals Inc Earnings Call TranscriptQ4 2023 Rigel Pharmaceuticals Inc Earnings Call Transcript
gurufocus.com - March 6 at 12:03 AM
RIGL Stock Earnings: Rigel Pharmaceuticals Beats Revenue for Q4 2023RIGL Stock Earnings: Rigel Pharmaceuticals Beats Revenue for Q4 2023
investorplace.com - March 5 at 9:01 PM
Rigel Pharmaceuticals (RIGL) Reports Break-Even Earnings for Q4Rigel Pharmaceuticals (RIGL) Reports Break-Even Earnings for Q4
zacks.com - March 5 at 6:11 PM
Rigel Announces Conference Call and Webcast to Report Fourth Quarter and Full Year 2023 Financial Results and Business UpdateRigel Announces Conference Call and Webcast to Report Fourth Quarter and Full Year 2023 Financial Results and Business Update
prnewswire.com - February 27 at 8:05 AM
Rigel Pharmaceuticals: Gavreto Deal Expands Growth ProspectsRigel Pharmaceuticals: Gavreto Deal Expands Growth Prospects
seekingalpha.com - February 26 at 6:28 PM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

AnaptysBio logo

AnaptysBio

NASDAQ:ANAB
AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics. Its products include Rosnilimab, an IgG1 antibody that targets PD-1+ T cells, resulting in their agonism or depletion, broadly impacting pathogenic drivers of autoimmune and inflammatory diseases; and ANB032, a non-depleting antibody that binds to the BTLA checkpoint receptor and inhibits activated T cell proliferation; ANB033, a novel anti-CD122 antagonist antibody that targets the shared common beta subunit of the receptors for IL-15 and IL-2; ANB101, a BDCA2 modulator antibody that specifically targets plasmacytoid dendritic cells (pDCs); and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.
Calliditas Therapeutics AB (publ) logo

Calliditas Therapeutics AB (publ)

NASDAQ:CALT
Calliditas Therapeutics AB (publ), a commercial-stage specialty pharmaceutical company, focused on identifying, developing, and commercializing pharmaceuticals products for treatments in orphan indications with initial focus on renal and hepatic diseases. It offers Nefecon, an oral formulation of budesonide that is an immunosuppressant for the treatment of the autoimmune renal disease immunoglobulin A nephropathy. The company's lead product candidate is Setanaxib, a NOX inhibitor that is in Phase 2b/3 clinical trial for the treatment of primary biliary cholangitis; and in Phase 2 clinical trial for the treatment of squamous cell carcinoma of the head and neck cancer and idiopathic pulmonary fibrosis, as well as for type 1 diabetic kidney disease. It also develops Budenofalk 3 mg oral capsules for the treatment of autoimmune hepatitis. The company was founded in 2004 and is headquartered in Stockholm, Sweden.
Organigram logo

Organigram

NASDAQ:OGI
Organigram Holdings Inc., through its subsidiaries, engages in the production and sale of cannabis and cannabis-derived products in Canada. It offers medical cannabis products, including whole flower, milled flower, pre-rolls, infused pre-rolls, vapes, gummies, and concentrates for medical retailers; adult use recreational cannabis under the SHRED, Holy Mountain, Big Bag O' Buds, Monjour, Trailblazer, SHRED'ems, Edison Cannabis Co., Edison JOLTS, Tremblant, and Laurentian brands. The company also engages in the wholesale shipping of cannabis plant cuttings, dried flowers, blends, pre-rolls, and cannabis derivative-based products to retailers and wholesalers for adult-use recreational cannabis. It sells its products through online, as well as consumer channels. The company was incorporated in 2010 and is headquartered in Toronto, Canada.
Provention Bio logo

Provention Bio

NASDAQ:PRVB
Provention Bio, Inc. is a clinical-stage biopharmaceutical company, which engages in the development and commercialization of novel therapeutics and solutions. Its products include PRV-031 for the interception of type 1 diabetes (T1D), PRV-015 for the treatment of gluten-free diet non-responding celiac disease, PRV-6527 for Crohn's disease, PRV-3279 for the treatment of lupus, and PRV-101 for the prevention of acute coxsackie virus B (CVB), and the prevention of type 1 diabetes (T1D) onset. The company was founded by Francisco Leon and Ashleigh Palmer on October 4, 2016 and is headquartered in Red Bank, NJ.
Rigel Pharmaceuticals logo

Rigel Pharmaceuticals

NASDAQ:RIGL
Rigel Pharmaceuticals, Inc., a biotechnology company, engages in discovering, developing, and providing therapies that enhance the lives of patients with hematologic disorders and cancer. The company's commercialized products include Tavalisse, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia; Rezlidhia, a non-intensive monotherapy for the treatment of adult patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation as detected by an FDA-approved test; and GAVRETO, a once daily, small molecule, oral, kinase inhibitor for the treatment of adult patients with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer, as well as for the treatment of adult and pediatric patients 12 years of age and older with advanced or metastatic RET fusion-positive thyroid cancer. It also develops R289, an oral IRAK1/4 Inhibitor, which is in Phase 1b clinical trials for the treatment of hematology-oncology, autoimmune, and inflammatory diseases; and a receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitor program in clinical development with partner Eli Lilly and Company. In addition, the company has product candidates in clinical development with partners BerGenBio ASA and Daiichi Sankyo. The company has strategic development collaboration with The University of Texas MD Anderson Cancer Center for the development of REZLIDHIA (Olutasidenib) in acute myeloid leukemia (AML) and other hematologic cancers. The company was incorporated in 1996 and is headquartered in South San Francisco, California.