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Protagonist Therapeutics Q4 2025 Earnings Report

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$100.77 +1.56 (+1.57%)
As of 11:28 AM Eastern
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Protagonist Therapeutics EPS Results

Actual EPS
-$0.69
Consensus EPS
-$0.53
Beat/Miss
Missed by -$0.16
One Year Ago EPS
N/A

Protagonist Therapeutics Revenue Results

Actual Revenue
$7.44 million
Expected Revenue
$14.92 million
Beat/Miss
Missed by -$7.48 million
YoY Revenue Growth
N/A

Protagonist Therapeutics Announcement Details

Quarter
Q4 2025
Time
Before Market Opens
Conference Call Date
Wednesday, February 25, 2026
Conference Call Time
12:30PM ET

Upcoming Earnings

Protagonist Therapeutics' Q2 2026 earnings is estimated for Wednesday, May 6, 2026, based on past reporting schedules

Earnings Documents

Protagonist Therapeutics Earnings Headlines

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About Protagonist Therapeutics

Protagonist Therapeutics (NASDAQ:PTGX) (NASDAQ: PTGX) is a clinical-stage biopharmaceutical company focused on the development of novel, orally administered peptide-based therapies for immune-mediated and other serious diseases. The company leverages its proprietary Peptide 2.0 platform to design peptides that target G protein–coupled receptors and cytokine receptors, with the goal of combining the potency of biologics with the convenience of oral administration. Protagonist’s approach aims to address unmet medical needs in areas where injectable therapies have been the standard of care.

Among its lead programs is PTG-100, an oral α4β7 integrin antagonist intended to block leukocyte migration to the gut in ulcerative colitis and Crohn’s disease. PTG-200, a selective interleukin-23 receptor antagonist, is in Phase 2 clinical trials for moderate to severe Crohn’s disease. The company’s PTG-300 program is a hepcidin mimetic being evaluated in hematologic disorders characterized by iron overload, including polycythemia vera and myelofibrosis.

Founded in 2006 and headquartered in San Diego, California, Protagonist Therapeutics conducts global clinical trials across North America, Europe and Asia. The company is led by a team of seasoned biotechnology executives with deep expertise in peptide drug discovery and development. Protagonist maintains collaborations with academic institutions and industry partners to advance its pipeline and explore additional therapeutic areas where oral peptide therapeutics may deliver significant patient benefit.

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