NASDAQ:SPRB Spruce Biosciences Q4 2025 Earnings Report $48.72 -0.30 (-0.61%) Closing price 09/25/2026 04:00 PM EasternExtended Trading$48.80 +0.09 (+0.17%) As of 09/25/2026 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. ProfileEarnings HistoryForecast Spruce Biosciences EPS ResultsActual EPS-$9.58Consensus EPS -$9.16Beat/MissMissed by -$0.42One Year Ago EPSN/ASpruce Biosciences Revenue ResultsActual RevenueN/AExpected RevenueN/ABeat/MissN/AYoY Revenue GrowthN/ASpruce Biosciences Announcement DetailsQuarterQ4 2025Date3/12/2026TimeBefore Market OpensConference Call DateMonday, March 9, 2026Conference Call Time7:00AM ETUpcoming EarningsSpruce Biosciences' Q3 2026 earnings is estimated for Monday, November 9, 2026, based on past reporting schedules, with a conference call scheduled on Wednesday, November 11, 2026 at 9:30 AM ET. Check back for transcripts, audio, and key financial metrics as they become available.Conference Call ResourcesPress Release (8-K)Annual Report (10-K)Earnings HistoryCompany ProfilePowered by Earnings DocumentsPress Release(8-K)Annual report(10-K) Spruce Biosciences Earnings HeadlinesSpruce Biosciences (NASDAQ:SPRB) Stock Rating Reaffirmed as Market Outperform by Citizens JmpSeptember 26 at 2:12 AM | americanbankingnews.comSpruce Biosciences, Inc. (NASDAQ:SPRB) Given Consensus Rating of "Moderate Buy" by AnalystsSeptember 23, 2026 | americanbankingnews.comYour $29.97 book is free todayWhy Some Traders Skip Stocks Entirely You don't need a big account to trade options. In fact, options can give you up to 12 times the leverage of stocks — with a fraction of the capital tied up. This free guide lays it all out in plain English — from A to Z, with step-by-step examples you can follow in your own account.September 27 at 1:00 AM | Profits Run (Ad)Spruce Biosciences (NASDAQ:SPRB) Coverage Initiated at Lake Street CapitalSeptember 19, 2026 | americanbankingnews.comLake Street initiates coverage of Spruce Biosciences at buySeptember 18, 2026 | msn.comSpruce Biosciences to Participate in the H.C. Wainwright 28th Annual Global Investment ConferenceSeptember 8, 2026 | businesswire.comSee More Spruce Biosciences Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Spruce Biosciences? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Spruce Biosciences and other key companies, straight to your email. Email Address About Spruce BiosciencesSpruce Biosciences (NASDAQ:SPRB) is a clinical-stage biopharmaceutical company focused on developing treatments for endocrine disorders. The company’s research has centered on therapies intended to address conditions involving hormone dysregulation and adrenal function. Its lead investigational product is tildacerfont, an oral, selective corticotropin-releasing factor type 1 (CRF1) receptor antagonist. The therapy is designed to reduce excessive adrenocorticotropic hormone (ACTH) signaling and adrenal androgen production, with development focused primarily on congenital adrenal hyperplasia (CAH), a rare inherited disorder affecting cortisol production. Tildacerfont has been evaluated in clinical studies involving patients with both classic and nonclassic forms of CAH. Spruce Biosciences has operated as a U.S.-based company serving the global biopharmaceutical market through clinical development activities and collaborations with research and medical communities. The company does not have a broadly marketed commercial product, and its activities have primarily involved research, clinical trials, regulatory planning and business development related to its endocrine-focused pipeline.View Spruce Biosciences ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Latest Articles MarketBeat Week in Review – 09/21 - 09/252 Cybersecurity Stocks Breaking Out as AI Continues to Be a TailwindCostco Ends Its Fiscal Year on a High Note, Eyes Big ExpansionCracker Barrel Stock Is Rallying Again, But the Turnaround Still Has a Traffic Problem5 Scary-Good Stocks With Strong October Catalysts and Breakout PotentialDarden Restaurants Serves Up Fresh Catalysts for a Stock Price RallySoFi Is Bypassing the Banking Bottleneck With Stablecoin Settlement Upcoming Earnings Micron Technology (9/30/2026)NIKE (10/1/2026)Accenture (10/1/2026)PepsiCo (10/8/2026)Delta Air Lines (10/9/2026)America Movil (10/13/2026)BlackRock (10/13/2026)Citigroup (10/13/2026)The Goldman Sachs Group (10/13/2026)JPMorgan Chase & Co. 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