NASDAQ:APLT Applied Therapeutics (APLT) Stock Price, News & Analysis $0.40 +0.03 (+7.05%) Closing price 04:00 PM EasternExtended Trading$0.39 -0.01 (-2.28%) As of 06:17 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock About Applied Therapeutics Stock (NASDAQ:APLT) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Applied Therapeutics alerts:Sign Up Key Stats Today's Range$0.36▼$0.4050-Day Range$0.30▼$0.6052-Week Range$0.30▼$10.62Volume2.36 million shsAverage Volume3.44 million shsMarket Capitalization$55.92 millionP/E RatioN/ADividend YieldN/APrice Target$6.10Consensus RatingModerate Buy Company Overview Applied Therapeutics is a clinical‐stage biopharmaceutical company dedicated to discovering and developing novel therapeutics that address the underlying causes of serious diseases. The company’s research focuses on metabolic and renal indications, aiming to bring differentiated treatments to patients with high unmet medical needs. Applied Therapeutics leverages a deep understanding of human biology and a precision medicine approach to identify targets that can modulate disease pathways and deliver meaningful clinical benefits. The company’s most advanced program targets mitochondrial dysfunction and impaired energy metabolism with its investigational small molecule, beraprost sodium. Initially developed as a prostacyclin analogue, beraprost is being repositioned by Applied Therapeutics to explore new indications in rare metabolic disorders and chronic kidney disease. In addition to beraprost, the company’s pipeline includes small molecules designed to restore cellular homeostasis by enhancing nicotinamide adenine dinucleotide (NAD+) levels. These programs are supported by preclinical and early‐stage clinical studies that aim to validate mechanisms of action and demonstrate safety and efficacy in targeted patient populations. Applied Therapeutics was founded in 2018 and is headquartered in New York City. Since its inception, the company has built a specialized team of drug discovery scientists, clinical development experts, and regulatory professionals. Applied Therapeutics collaborates with academic institutions and biotech partners to accelerate the translation of its research into clinical milestones. The company’s strategic alliances and in-licensing agreements have expanded its capabilities in medicinal chemistry, preclinical toxicology, and clinical trial execution. Under the leadership of President and Chief Executive Officer James (“Jim”) McArthur, Applied Therapeutics has advanced from an early research outfit to a publicly traded biotech firm listed on the Nasdaq exchange. The management team includes seasoned executives with prior experience at leading pharmaceutical and biotechnology companies, providing strong governance and operational expertise. As Applied Therapeutics progresses its clinical programs, the company remains committed to delivering innovative therapies that improve patient outcomes in metabolic and renal diseases worldwide.AI Generated. May Contain Errors. Read More Applied Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks76th Percentile Overall ScoreAPLT MarketRank™: Applied Therapeutics scored higher than 76% of companies evaluated by MarketBeat, and ranked 239th out of 921 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.3 / 5Analyst RatingModerate Buy Consensus RatingApplied Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.50, and is based on 3 buy ratings, 3 hold ratings, and no sell ratings.Amount of Analyst CoverageApplied Therapeutics has only been the subject of 1 research reports in the past 90 days.Read more about Applied Therapeutics' stock forecast and price target. Earnings and Valuation1.3 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Applied Therapeutics are expected to grow in the coming year, from ($0.65) to ($0.62) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Applied Therapeutics is -0.92, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Applied Therapeutics is -0.92, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioApplied Therapeutics has a P/B Ratio of 0.81. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Applied Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted15.31% of the float of Applied Therapeutics has been sold short.Short Interest Ratio / Days to CoverApplied Therapeutics has a short interest ratio ("days to cover") of 9.9.Change versus previous monthShort interest in Applied Therapeutics has recently increased by 18.43%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldApplied Therapeutics does not currently pay a dividend.Dividend GrowthApplied Therapeutics does not have a long track record of dividend growth. Sustainability and ESG4.7 / 5Environmental Score-0.88 Percentage of Shares Shorted15.31% of the float of Applied Therapeutics has been sold short.Short Interest Ratio / Days to CoverApplied Therapeutics has a short interest ratio ("days to cover") of 9.9.Change versus previous monthShort interest in Applied Therapeutics has recently increased by 18.43%, indicating that investor sentiment is decreasing significantly. News and Social Media0.6 / 5News SentimentN/A News Coverage This WeekMarketBeat has tracked 1 news article for Applied Therapeutics this week, compared to 8 articles on an average week.Search InterestOnly 2 people have searched for APLT on MarketBeat in the last 30 days. This is a decrease of -60% compared to the previous 30 days.MarketBeat Follows5 people have added Applied Therapeutics to their MarketBeat watchlist in the last 30 days. This is an increase of 150% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Applied Therapeutics insiders have not sold or bought any company stock.Percentage Held by InsidersOnly 1.60% of the stock of Applied Therapeutics is held by insiders.Percentage Held by Institutions98.31% of the stock of Applied Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Applied Therapeutics' insider trading history. Receive APLT Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Applied Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address APLT Stock News HeadlinesBrokerages Set Applied Therapeutics Inc. (NASDAQ:APLT) Target Price at $6.10July 6 at 2:09 AM | americanbankingnews.comApplied Therapeutics, Inc. (APLT) - Yahoo FinanceJune 24, 2025 | finance.yahoo.comIs Elon's empire crumbling?The Tesla Shock Nobody Sees Coming While headlines scream "Tesla is doomed"... Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as July 23rd.July 9 at 2:00 AM | Brownstone Research (Ad)Applied Therapeutics Announces Key Leadership AppointmentsJune 17, 2025 | globenewswire.comApplied announces INSPIRE Phase 2/3 trial primary endpoint not significantMay 18, 2025 | msn.comApplied Therapeutics Presents Full 12-Month Clinical Results and New Topline Data from INSPIRE Phase 2/3 Trial of Govorestat in CMT-SORD in Late-Breaking Oral Presentation at the Peripheral Nerve Society 2025 Annual MeetingMay 18, 2025 | globenewswire.comApplied Therapeutics Reports First Quarter 2025 Financial ResultsMay 13, 2025 | globenewswire.comApplied Therapeutics Announces Acceptance of Late-Breaking Abstract for Oral Presentation at the Peripheral Nerve Society 2025 Annual MeetingMay 9, 2025 | globenewswire.comSee More Headlines APLT Stock Analysis - Frequently Asked Questions How have APLT shares performed this year? Applied Therapeutics' stock was trading at $0.8562 at the beginning of 2025. Since then, APLT shares have decreased by 53.9% and is now trading at $0.3950. How were Applied Therapeutics' earnings last quarter? Applied Therapeutics Inc. (NASDAQ:APLT) issued its quarterly earnings data on Monday, April, 14th. The company reported ($0.24) EPS for the quarter, missing the consensus estimate of ($0.18) by $0.06. The firm earned $0 million during the quarter, compared to analyst estimates of $0.61 million. When did Applied Therapeutics IPO? Applied Therapeutics (APLT) raised $60 million in an initial public offering on the week of May 13th 2019. The company issued 4,000,000 shares at a price of $14.00-$16.00 per share. Citigroup, Cowen and UBS Investment Bank served as the underwriters for the IPO and Baird was co-manager. How do I buy shares of Applied Therapeutics? Shares of APLT stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Applied Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Applied Therapeutics investors own include NVIDIA (NVDA), Broadcom (AVGO), Meta Platforms (META), Adobe (ADBE), Arista Networks (ANET), Advanced Micro Devices (AMD) and ServiceNow (NOW). Company Calendar Last Earnings4/14/2025Today7/09/2025Next Earnings (Estimated)8/06/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:APLT CIK1697532 Webwww.appliedtherapeutics.com Phone(212) 220-9226FaxN/AEmployees30Year Founded2017Price Target and Rating Average Price Target for Applied Therapeutics$6.10 High Price Target$14.00 Low Price Target$1.50 Potential Upside/Downside+1,444.3%Consensus RatingModerate Buy Rating Score (0-4)2.50 Research Coverage6 Analysts Profitability EPS (Trailing Twelve Months)($0.43) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$105.62 million Net MarginsN/A Pretax Margin-16,357.52% Return on Equity-184.67% Return on Assets-84.02% Debt Debt-to-Equity RatioN/A Current Ratio3.00 Quick Ratio3.00 Sales & Book Value Annual Sales$460 thousand Price / Sales121.57 Cash FlowN/A Price / Cash FlowN/A Book Value$0.49 per share Price / Book0.81Miscellaneous Outstanding Shares141,580,000Free Float139,311,000Market Cap$55.92 million OptionableOptionable Beta1.82 Social Links Ten Starter Stocks For Beginners to Buy NowJust getting into the stock market? 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