Is PMVP or APLT more profitable?

PMV Pharmaceuticals' return on equity of -68.98% beat Applied Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets PMV Pharmaceuticals N/A -68.98% -62.70% Applied Therapeutics N/A -340.84% -175.00%

Which has stronger valuation and earnings, APLT or OKYO?

OKYO Pharma has lower revenue, but higher earnings than Applied Therapeutics. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio Applied Therapeutics $1M 15.86 -$105.62M -$0.10 N/A OKYO Pharma N/A N/A -$4.71M N/A N/A

Is APLT or OKYO more profitable?

OKYO Pharma's return on equity of 0.00% beat Applied Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets Applied Therapeutics N/A -340.84% -175.00% OKYO Pharma N/A N/A N/A

Is APLT or EXOZ more profitable?

eXoZymes' return on equity of -220.63% beat Applied Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets Applied Therapeutics N/A -340.84% -175.00% eXoZymes N/A -220.63% -141.26%

Is INKT or APLT more profitable?

MiNK Therapeutics' return on equity of 0.00% beat Applied Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets MiNK Therapeutics N/A N/A -118.57% Applied Therapeutics N/A -340.84% -175.00%

Applied Therapeutics (APLT) Competitors

$0.10 0.00 (0.00%)

As of 06/29/2026

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APLT vs. PMVP, OKYO, EXOZ, INKT, and XLO

Should you buy Applied Therapeutics stock or one of its competitors? MarketBeat compares Applied Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Applied Therapeutics include PMV Pharmaceuticals (PMVP), OKYO Pharma (OKYO), eXoZymes (EXOZ), MiNK Therapeutics (INKT), and Xilio Therapeutics (XLO). These companies are all part of the "pharmaceutical products" industry.

How does Applied Therapeutics compare to PMV Pharmaceuticals?

PMV Pharmaceuticals (NASDAQ:PMVP) and Applied Therapeutics (NASDAQ:APLT) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their risk, institutional ownership, valuation, media sentiment, dividends, analyst recommendations, profitability and earnings.

90.2% of PMV Pharmaceuticals shares are held by institutional investors. Comparatively, 98.3% of Applied Therapeutics shares are held by institutional investors. 7.6% of PMV Pharmaceuticals shares are held by company insiders. Comparatively, 1.6% of Applied Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

PMV Pharmaceuticals' return on equity of -68.98% beat Applied Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
PMV Pharmaceuticals	N/A	-68.98%	-62.70%
Applied Therapeutics	N/A	-340.84%	-175.00%

PMV Pharmaceuticals has a beta of 1.36, meaning that its stock price is 36% more volatile than the broader market. Comparatively, Applied Therapeutics has a beta of 2.08, meaning that its stock price is 108% more volatile than the broader market.

PMV Pharmaceuticals currently has a consensus target price of $5.00, suggesting a potential upside of 280.23%. Applied Therapeutics has a consensus target price of $1.00, suggesting a potential upside of 870.87%. Given Applied Therapeutics' higher possible upside, analysts plainly believe Applied Therapeutics is more favorable than PMV Pharmaceuticals.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
PMV Pharmaceuticals	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.67
Applied Therapeutics	1 Sell rating(s)	2 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.67

PMV Pharmaceuticals has higher earnings, but lower revenue than Applied Therapeutics. Applied Therapeutics is trading at a lower price-to-earnings ratio than PMV Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
PMV Pharmaceuticals	N/A	N/A	-$77.74M	-$1.49	N/A
Applied Therapeutics	$1M	15.86	-$105.62M	-$0.10	N/A

In the previous week, PMV Pharmaceuticals had 2 more articles in the media than Applied Therapeutics. MarketBeat recorded 2 mentions for PMV Pharmaceuticals and 0 mentions for Applied Therapeutics. PMV Pharmaceuticals' average media sentiment score of 0.96 beat Applied Therapeutics' score of 0.00 indicating that PMV Pharmaceuticals is being referred to more favorably in the media.

Company	Overall Sentiment
PMV Pharmaceuticals	Positive
Applied Therapeutics	Neutral

Summary

PMV Pharmaceuticals beats Applied Therapeutics on 10 of the 15 factors compared between the two stocks.

How does Applied Therapeutics compare to OKYO Pharma?

Applied Therapeutics (NASDAQ:APLT) and OKYO Pharma (NASDAQ:OKYO) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, analyst recommendations, earnings, media sentiment, risk, institutional ownership, valuation and profitability.

Applied Therapeutics presently has a consensus price target of $1.00, indicating a potential upside of 870.87%. OKYO Pharma has a consensus price target of $6.33, indicating a potential upside of 325.06%. Given Applied Therapeutics' higher possible upside, equities research analysts clearly believe Applied Therapeutics is more favorable than OKYO Pharma.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Applied Therapeutics	1 Sell rating(s)	2 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.67
OKYO Pharma	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40

Applied Therapeutics has a beta of 2.08, meaning that its share price is 108% more volatile than the broader market. Comparatively, OKYO Pharma has a beta of 0.02, meaning that its share price is 98% less volatile than the broader market.

OKYO Pharma's return on equity of 0.00% beat Applied Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Applied Therapeutics	N/A	-340.84%	-175.00%
OKYO Pharma	N/A	N/A	N/A

98.3% of Applied Therapeutics shares are held by institutional investors. Comparatively, 3.0% of OKYO Pharma shares are held by institutional investors. 1.6% of Applied Therapeutics shares are held by insiders. Comparatively, 40.5% of OKYO Pharma shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, OKYO Pharma had 3 more articles in the media than Applied Therapeutics. MarketBeat recorded 3 mentions for OKYO Pharma and 0 mentions for Applied Therapeutics. OKYO Pharma's average media sentiment score of 0.45 beat Applied Therapeutics' score of 0.00 indicating that OKYO Pharma is being referred to more favorably in the news media.

Company	Overall Sentiment
Applied Therapeutics	Neutral
OKYO Pharma	Neutral

OKYO Pharma has lower revenue, but higher earnings than Applied Therapeutics.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Applied Therapeutics	$1M	15.86	-$105.62M	-$0.10	N/A
OKYO Pharma	N/A	N/A	-$4.71M	N/A	N/A

Summary

OKYO Pharma beats Applied Therapeutics on 8 of the 12 factors compared between the two stocks.

How does Applied Therapeutics compare to eXoZymes?

Applied Therapeutics (NASDAQ:APLT) and eXoZymes (NASDAQ:EXOZ) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their risk, earnings, analyst recommendations, media sentiment, valuation, profitability, dividends and institutional ownership.

98.3% of Applied Therapeutics shares are held by institutional investors. 1.6% of Applied Therapeutics shares are held by insiders. Comparatively, 72.4% of eXoZymes shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

eXoZymes has lower revenue, but higher earnings than Applied Therapeutics. eXoZymes is trading at a lower price-to-earnings ratio than Applied Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Applied Therapeutics	$1M	15.86	-$105.62M	-$0.10	N/A
eXoZymes	$70K	1,001.00	-$9.16M	-$1.14	N/A

Applied Therapeutics has a beta of 2.08, suggesting that its stock price is 108% more volatile than the broader market. Comparatively, eXoZymes has a beta of 2.66, suggesting that its stock price is 166% more volatile than the broader market.

Applied Therapeutics currently has a consensus target price of $1.00, indicating a potential upside of 870.87%. Given Applied Therapeutics' stronger consensus rating and higher possible upside, equities research analysts plainly believe Applied Therapeutics is more favorable than eXoZymes.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Applied Therapeutics	1 Sell rating(s)	2 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.67
eXoZymes	1 Sell rating(s)	0 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.00

eXoZymes' return on equity of -220.63% beat Applied Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Applied Therapeutics	N/A	-340.84%	-175.00%
eXoZymes	N/A	-220.63%	-141.26%

In the previous week, eXoZymes had 2 more articles in the media than Applied Therapeutics. MarketBeat recorded 2 mentions for eXoZymes and 0 mentions for Applied Therapeutics. eXoZymes' average media sentiment score of 1.19 beat Applied Therapeutics' score of 0.00 indicating that eXoZymes is being referred to more favorably in the news media.

Company	Overall Sentiment
Applied Therapeutics	Neutral
eXoZymes	Positive

Summary

eXoZymes beats Applied Therapeutics on 8 of the 14 factors compared between the two stocks.

How does Applied Therapeutics compare to MiNK Therapeutics?

MiNK Therapeutics (NASDAQ:INKT) and Applied Therapeutics (NASDAQ:APLT) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their analyst recommendations, risk, earnings, profitability, dividends, valuation, institutional ownership and media sentiment.

MiNK Therapeutics has a beta of 0.47, indicating that its stock price is 53% less volatile than the broader market. Comparatively, Applied Therapeutics has a beta of 2.08, indicating that its stock price is 108% more volatile than the broader market.

MiNK Therapeutics has higher earnings, but lower revenue than Applied Therapeutics. MiNK Therapeutics is trading at a lower price-to-earnings ratio than Applied Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
MiNK Therapeutics	N/A	N/A	-$12.49M	-$2.84	N/A
Applied Therapeutics	$1M	15.86	-$105.62M	-$0.10	N/A

2.9% of MiNK Therapeutics shares are held by institutional investors. Comparatively, 98.3% of Applied Therapeutics shares are held by institutional investors. 20.4% of MiNK Therapeutics shares are held by company insiders. Comparatively, 1.6% of Applied Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

MiNK Therapeutics currently has a consensus target price of $35.00, indicating a potential upside of 194.61%. Applied Therapeutics has a consensus target price of $1.00, indicating a potential upside of 870.87%. Given Applied Therapeutics' higher possible upside, analysts plainly believe Applied Therapeutics is more favorable than MiNK Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
MiNK Therapeutics	1 Sell rating(s)	2 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.40
Applied Therapeutics	1 Sell rating(s)	2 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.67

MiNK Therapeutics' return on equity of 0.00% beat Applied Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
MiNK Therapeutics	N/A	N/A	-118.57%
Applied Therapeutics	N/A	-340.84%	-175.00%

In the previous week, MiNK Therapeutics had 1 more articles in the media than Applied Therapeutics. MarketBeat recorded 1 mentions for MiNK Therapeutics and 0 mentions for Applied Therapeutics. MiNK Therapeutics' average media sentiment score of 1.89 beat Applied Therapeutics' score of 0.00 indicating that MiNK Therapeutics is being referred to more favorably in the media.

Company	Overall Sentiment
MiNK Therapeutics	Very Positive
Applied Therapeutics	Neutral

Summary

MiNK Therapeutics beats Applied Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Applied Therapeutics compare to Xilio Therapeutics?

Applied Therapeutics (NASDAQ:APLT) and Xilio Therapeutics (NASDAQ:XLO) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their profitability, media sentiment, valuation, institutional ownership, dividends, analyst recommendations, risk and earnings.

Applied Therapeutics has a beta of 2.08, suggesting that its share price is 108% more volatile than the broader market. Comparatively, Xilio Therapeutics has a beta of -0.12, suggesting that its share price is 112% less volatile than the broader market.

In the previous week, Xilio Therapeutics had 3 more articles in the media than Applied Therapeutics. MarketBeat recorded 3 mentions for Xilio Therapeutics and 0 mentions for Applied Therapeutics. Xilio Therapeutics' average media sentiment score of 0.71 beat Applied Therapeutics' score of 0.00 indicating that Xilio Therapeutics is being referred to more favorably in the news media.

Company	Overall Sentiment
Applied Therapeutics	Neutral
Xilio Therapeutics	Positive

Applied Therapeutics has a net margin of 0.00% compared to Xilio Therapeutics' net margin of -58.52%. Xilio Therapeutics' return on equity of -151.42% beat Applied Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Applied Therapeutics	N/A	-340.84%	-175.00%
Xilio Therapeutics	-58.52%	-151.42%	-27.61%

98.3% of Applied Therapeutics shares are held by institutional investors. Comparatively, 54.3% of Xilio Therapeutics shares are held by institutional investors. 1.6% of Applied Therapeutics shares are held by insiders. Comparatively, 7.5% of Xilio Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Applied Therapeutics presently has a consensus target price of $1.00, suggesting a potential upside of 870.87%. Xilio Therapeutics has a consensus target price of $28.00, suggesting a potential upside of 189.56%. Given Applied Therapeutics' higher possible upside, research analysts plainly believe Applied Therapeutics is more favorable than Xilio Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Applied Therapeutics	1 Sell rating(s)	2 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.67
Xilio Therapeutics	1 Sell rating(s)	0 Hold rating(s)	0 Buy rating(s)	1 Strong Buy rating(s)	2.50

Xilio Therapeutics has higher revenue and earnings than Applied Therapeutics. Xilio Therapeutics is trading at a lower price-to-earnings ratio than Applied Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Applied Therapeutics	$1M	15.86	-$105.62M	-$0.10	N/A
Xilio Therapeutics	$53.48M	1.19	-$35.04M	-$3.55	N/A

Summary

Xilio Therapeutics beats Applied Therapeutics on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding APLT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

APLT vs. The Competition

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Metric	Applied Therapeutics	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$15.86M	$3.64B	$6.78B	$12.58B
Dividend Yield	N/A	2.21%	2.66%	6.21%
P/E Ratio	-1.03	21.23	27.32	24.89
Price / Sales	15.86	336.45	559.95	116.34
Price / Cash	N/A	62.10	29.14	36.96
Price / Book	0.21	8.81	11.07	6.57
Net Income	-$105.62M	$23.81M	$3.57B	$336.70M
7 Day Performance	N/A	3.60%	2.49%	3.24%
1 Month Performance	N/A	1.59%	0.83%	1.67%
1 Year Performance	-66.89%	69.67%	36.80%	31.94%

Applied Therapeutics Competitors List

Export

Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
APLT Applied Therapeutics	N/A	$0.10 flat	$1.00 +870.9%	N/A	$15.86M	$1M	N/A	30
PMVP PMV Pharmaceuticals	3.5015 of 5 stars	$1.15 -2.5%	$5.00 +334.8%	+20.6%	$62.93M	N/A	N/A	50
OKYO OKYO Pharma	2.9484 of 5 stars	$1.54 -0.6%	$6.33 +311.3%	-38.0%	$62.86M	N/A	N/A	7
EXOZ eXoZymes	0.9134 of 5 stars	$7.40 +3.6%	N/A	-19.0%	$60.54M	$70K	N/A	29	Positive News
INKT MiNK Therapeutics	3.3655 of 5 stars	$11.31 -6.6%	$35.00 +209.5%	+70.6%	$60.33M	N/A	N/A	30	Positive News

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This page (NASDAQ:APLT) was last updated on 6/30/2026 by MarketBeat.com Staff.

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Applied Therapeutics (APLT) Competitors

APLT vs. PMVP, OKYO, EXOZ, INKT, and XLO

How does Applied Therapeutics compare to PMV Pharmaceuticals?

Summary

How does Applied Therapeutics compare to OKYO Pharma?

Summary

How does Applied Therapeutics compare to eXoZymes?

Summary

How does Applied Therapeutics compare to MiNK Therapeutics?

Summary

How does Applied Therapeutics compare to Xilio Therapeutics?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

APLT vs. The Competition

Applied Therapeutics Competitors List

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Applied Therapeutics (APLT) Competitors

APLT vs. PMVP, OKYO, EXOZ, INKT, and XLO

How does Applied Therapeutics compare to PMV Pharmaceuticals?

Do insiders & institutionals believe in PMVP or APLT?

Is PMVP or APLT more profitable?

Which has more risk & volatility, PMVP or APLT?

Do analysts recommend PMVP or APLT?

Which has better earnings and valuation, PMVP or APLT?

Does the media favor PMVP or APLT?

Summary

How does Applied Therapeutics compare to OKYO Pharma?

Do analysts recommend APLT or OKYO?

Which has more risk and volatility, APLT or OKYO?

Is APLT or OKYO more profitable?

Do institutionals and insiders have more ownership in APLT or OKYO?

Does the media favor APLT or OKYO?

Which has stronger valuation and earnings, APLT or OKYO?

Summary

How does Applied Therapeutics compare to eXoZymes?

Do insiders & institutionals have more ownership in APLT or EXOZ?

Which has better earnings and valuation, APLT or EXOZ?

Which has more volatility & risk, APLT or EXOZ?

Do analysts recommend APLT or EXOZ?

Is APLT or EXOZ more profitable?

Does the media prefer APLT or EXOZ?

Summary

How does Applied Therapeutics compare to MiNK Therapeutics?

Which has more volatility and risk, INKT or APLT?

Which has preferable valuation and earnings, INKT or APLT?

Do institutionals and insiders have more ownership in INKT or APLT?

Do analysts recommend INKT or APLT?

Is INKT or APLT more profitable?

Does the media prefer INKT or APLT?

Summary

How does Applied Therapeutics compare to Xilio Therapeutics?

Which has more volatility and risk, APLT or XLO?

Does the media favor APLT or XLO?

Is APLT or XLO more profitable?

Do insiders and institutionals hold more shares of APLT or XLO?

Do analysts prefer APLT or XLO?

Which has better valuation and earnings, APLT or XLO?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

APLT vs. The Competition

Applied Therapeutics Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools