AnaptysBio (ANAB) Stock Price, News & Analysis

Company Overview

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics. Its products include Rosnilimab, an IgG1 antibody that targets PD-1+ T cells, resulting in their agonism or depletion, broadly impacting pathogenic drivers of autoimmune and inflammatory diseases; and ANB032, a non-depleting antibody that binds to the BTLA checkpoint receptor and inhibits activated T cell proliferation; ANB033, a novel anti-CD122 antagonist antibody that targets the shared common beta subunit of the receptors for IL-15 and IL-2; ANB101, a BDCA2 modulator antibody that specifically targets plasmacytoid dendritic cells (pDCs); and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

Key Stats

• Today's Range: $20.09 to $21.04
• 50-Day Range: $19.79 to $27.00
• 52-Week Range: $12.21 to $40.70
• Volume: 257,922 shs
• Average Volume: 483,118 shs
• Market Capitalization: $566.16 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $46.13
• Consensus Rating: Moderate Buy

AnaptysBio Stock Analysis - MarketRank™

AnaptysBio scored higher than 60% of companies evaluated by MarketBeat, and ranked 412th out of 932 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.4 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

AnaptysBio has received a consensus rating of Moderate Buy. The company's average rating score is 2.80, and is based on 6 buy ratings, 3 hold ratings, and no sell ratings.

Amount of Analyst Coverage

AnaptysBio has been the subject of 5 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for AnaptysBio are expected to grow in the coming year, from ($6.08) to ($5.36) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of AnaptysBio is -4.51, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of AnaptysBio is -4.51, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Short Interest

• Score: 0.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

38.01% of the float of AnaptysBio has been sold short.

Short Interest Ratio / Days to Cover

AnaptysBio has a short interest ratio ("days to cover") of 16.5, which indicates bearish sentiment.

Change versus previous month

Short interest in AnaptysBio has recently increased by 1.92%, indicating that investor sentiment is decreasing.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

AnaptysBio does not currently pay a dividend.

Dividend Growth

AnaptysBio does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

38.01% of the float of AnaptysBio has been sold short.

Short Interest Ratio / Days to Cover

AnaptysBio has a short interest ratio ("days to cover") of 16.5, which indicates bearish sentiment.

Change versus previous month

Short interest in AnaptysBio has recently increased by 1.92%, indicating that investor sentiment is decreasing.

News and Social Media

• Score: 2.7 / 5
• News Sentiment: 0.90

News Sentiment

AnaptysBio has a news sentiment score of 0.90. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.66 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 3 news articles for AnaptysBio this week, compared to 5 articles on an average week.

Search Interest

5 people have searched for ANAB on MarketBeat in the last 30 days.

MarketBeat Follows

Only 1 people have added AnaptysBio to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, AnaptysBio insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $493,202.00 in company stock.

Percentage Held by Insiders

33.50% of the stock of AnaptysBio is held by insiders. A high percentage of insider ownership can be a sign of company health.

ANAB Stock Analysis - Frequently Asked Questions

How have ANAB shares performed this year?

AnaptysBio's stock was trading at $13.24 at the beginning of 2025. Since then, ANAB shares have increased by 52.7% and is now trading at $20.22.

How were AnaptysBio's earnings last quarter?

AnaptysBio, Inc. (NASDAQ:ANAB) announced its quarterly earnings results on Wednesday, August, 6th. The biotechnology company reported ($1.34) earnings per share (EPS) for the quarter, beating analysts' consensus estimates of ($1.50) by $0.16. The biotechnology company earned $22.26 million during the quarter, compared to analysts' expectations of $11.55 million. AnaptysBio had a negative net margin of 107.66% and a negative trailing twelve-month return on equity of 366.98%.

Is AnaptysBio buying back stock?

AnaptysBio's board approved a stock buyback program on Monday, March 24th 2025, which permits the company to repurchase $75,000,000 in shares, according to EventVestor. This means that the company could repurchase up to 13.1% of its stock through open market purchases. Stock repurchase programs are often an indication that the company's leadership believes its stock is undervalued.

When did AnaptysBio IPO?

AnaptysBio (ANAB) raised $60 million in an initial public offering on Thursday, January 26th 2017. The company issued 4,000,000 shares at a price of $14.00-$16.00 per share. Credit Suisse and Stifel acted as the underwriters for the IPO and JMP Securities and Wedbush PacGrow were co-managers.

Who are AnaptysBio's major shareholders?

Top institutional investors of AnaptysBio include First Light Asset Management LLC (12.64%), Bank of America Corp DE (3.85%), Sofinnova Investments Inc. (3.69%) and 683 Capital Management LLC (1.79%). Insiders that own company stock include Ecor1 Capital, Llc, Daniel Faga, Paul F Lizzul, Eric J Loumeau, Hollings Renton, Dennis Mulroy and Dennis M Fenton.
View institutional ownership trends.

How do I buy shares of AnaptysBio?

Shares of ANAB stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of AnaptysBio own?

Based on aggregate information from My MarketBeat watchlists, some other companies that AnaptysBio investors own include Meta Platforms (META), NVIDIA (NVDA), Tesla (TSLA), Alibaba Group (BABA), Advanced Micro Devices (AMD), Moderna (MRNA) and Alphabet (GOOG).

Company Calendar

• Last Earnings: 8/06/2025
• Today: 8/23/2025
• Next Earnings (Estimated): 11/04/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:ANAB
• CIK: 1370053
• Web: www.anaptysbio.com
• Phone: (858) 362-6295
• Fax: N/A
• Employees: 100
• Year Founded: 2005

Price Target and Rating

• Average Price Target for AnaptysBio: $46.13
• High Price Target: $90.00
• Low Price Target: $20.00
• Potential Upside/Downside: +128.1%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.80
• Research Coverage: 10 Analysts

Profitability

• EPS (Trailing Twelve Months): ($4.48)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$145.23 million
• Net Margins: -107.66%
• Pretax Margin: -107.59%
• Return on Equity: -366.98%
• Return on Assets: -30.58%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 8.22
• Quick Ratio: 8.22

Sales & Book Value

• Annual Sales: $91.28 million
• Price / Sales: 6.20
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: ($1.60) per share
• Price / Book: -12.64

Miscellaneous

• Outstanding Shares: 28,000,000
• Free Float: 18,618,000
• Market Cap: $566.16 million
• Optionable: Optionable
• Beta: -0.20