NASDAQ:CTMX CytomX Therapeutics (CTMX) Stock Price, News & Analysis $2.72 -0.03 (-1.09%) Closing price 09/30/2026 04:00 PM EasternExtended Trading$2.71 -0.01 (-0.37%) As of 05:17 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About CytomX Therapeutics Stock (NASDAQ:CTMX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get CytomX Therapeutics alerts:Sign Up Key Stats Today's Range$2.70▼$2.8050-Day Range$2.69▼$3.7252-Week Range$2.60▼$8.21Volume3.22 million shsAverage Volume4.13 million shsMarket Capitalization$592.69 millionP/E RatioN/ADividend YieldN/APrice Target$11.90Consensus RatingModerate Buy Company Overview CytomX Therapeutics, Inc. (NASDAQ: CTMX) is a clinical-stage biopharmaceutical company focused on developing cancer therapies designed to selectively activate in the tumor microenvironment. The company’s Probody therapeutic platform uses molecular masking technology intended to limit antibody activity in healthy tissue and enable activation by proteases that are more prevalent in tumors. CytomX’s pipeline includes investigational therapies spanning several modalities, including Probody drug conjugates, T-cell engagers and cytokine-based treatments. Its programs have included CX-2051, a CEACAM5-directed Probody drug conjugate; CX-904, a conditionally active T-cell engager targeting EGFR; and CX-801, an investigational tumor-targeted interferon-based therapy. These candidates are being studied for potential use in solid tumors, although the company does not currently market an approved product. Founded in 2008 and headquartered in South San Francisco, California, CytomX has advanced its programs through internal research and collaborations with pharmaceutical companies, including Astellas Pharma and Bristol Myers Squibb. The company’s therapies are intended for development and potential commercialization in international oncology markets, subject to clinical and regulatory approval. CytomX has been led by President and Chief Executive Officer Sean McCarthy, Ph.D., a co-founder of the company.AI Generated. May Contain Errors. Read More CytomX Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks40th Percentile Overall ScoreCTMX MarketRank™: CytomX Therapeutics scored higher than 40% of companies evaluated by MarketBeat, and ranked 633rd out of 891 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.2 / 5Analyst RatingModerate Buy Consensus RatingCytomX Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.83, and is based on 1 strong buy rating, 9 buy ratings, 1 hold rating, and 1 sell rating.Upside PotentialCytomX Therapeutics has a consensus price target of $11.90, representing about 337.5% upside from its current price of $2.72.Amount of Analyst CoverageCytomX Therapeutics has only been the subject of 4 research reports in the past 90 days.Read more about CytomX Therapeutics' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for CytomX Therapeutics are expected to decrease in the coming year, from ($0.40) to ($0.52) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of CytomX Therapeutics is -5.44, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of CytomX Therapeutics is -5.44, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioCytomX Therapeutics has a P/B Ratio of 4.69. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about CytomX Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted18.43% of the float of CytomX Therapeutics has been sold short.Short Interest Ratio / Days to CoverCytomX Therapeutics has a short interest ratio ("days to cover") of 9.29.Change versus previous monthShort interest in CytomX Therapeutics has recently increased by 15.30%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldCytomX Therapeutics does not currently pay a dividend.Dividend GrowthCytomX Therapeutics does not have a long track record of dividend growth. News and Social Media1.6 / 5News Sentiment0.53 News SentimentCytomX Therapeutics has a news sentiment score of 0.53. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.74 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 4 news articles for CytomX Therapeutics this week, compared to 4 articles on an average week.Search InterestOnly 7 people have searched for CTMX on MarketBeat in the last 30 days. This is a decrease of 0% compared to the previous 30 days.MarketBeat FollowsOnly 1 people have added CytomX Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership0.9 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, CytomX Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders3.80% of the stock of CytomX Therapeutics is held by insiders.Percentage Held by Institutions67.77% of the stock of CytomX Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about CytomX Therapeutics' insider trading history. Receive CTMX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for CytomX Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. CTMX Stock News HeadlinesComparing IDEAYA Biosciences (NASDAQ:IDYA) and CytomX Therapeutics (NASDAQ:CTMX)September 27, 2026 | americanbankingnews.comCytomX Therapeutics, Inc. (CTMX) Presents at Morgan Stanley 24th Annual Global Healthcare Conference TranscriptSeptember 14, 2026 | seekingalpha.comSmall Colorado Company (Backed by Sam Altman) Could Save U.S. Power GridA small Colorado company has secured rights to technology that could prevent the U.S. public power grid from collapsing — and billionaire Sam Altman is now an investor. This under-the-radar firm is drawing serious attention from those watching the energy infrastructure space closely. | Altimetry (Ad)CytomX Therapeutics, Inc. (CTMX) Presents at Wells Fargo 21st Annual Healthcare Conference - SlideshowSeptember 10, 2026 | seekingalpha.comCytomX Therapeutics to Present at Upcoming September Investor ConferencesSeptember 1, 2026 | globenewswire.comCytomX Therapeutics Announces FDA Fast Track Designation for Varsetatug masetecan (“Varseta-M”) for Relapsed/Refractory Metastatic Colorectal Cancer (R/R mCRC)August 27, 2026 | globenewswire.comCytomX Therapeutics: Promising Varseta-M With Comfortable RunwayAugust 12, 2026 | seekingalpha.comCytomX Therapeutics, Inc. (CTMX) Q2 2026 Earnings Call TranscriptAugust 6, 2026 | seekingalpha.comSee More Headlines CTMX Stock Analysis - Frequently Asked Questions How have CTMX shares performed this year? CytomX Therapeutics' stock was trading at $4.26 at the beginning of 2026. Since then, CTMX shares have decreased by 36.2% and is now trading at $2.72. How were CytomX Therapeutics' earnings last quarter? CytomX Therapeutics, Inc. (NASDAQ:CTMX) posted its quarterly earnings data on Thursday, August, 6th. The biotechnology company reported ($0.09) EPS for the quarter, missing the consensus estimate of ($0.08) by $0.01. The biotechnology company earned $1.42 million during the quarter, compared to analyst estimates of $12.39 million. CytomX Therapeutics had a negative trailing twelve-month return on equity of 38.46% and a negative net margin of 435.21%. Read the conference call transcript. When did CytomX Therapeutics IPO? CytomX Therapeutics (CTMX) raised $100 million in an initial public offering on Thursday, October 8th 2015. The company issued 6,666,667 shares at $14.00-$16.00 per share. How do I buy shares of CytomX Therapeutics? Shares of CTMX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of CytomX Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that CytomX Therapeutics investors own include NVIDIA (NVDA), Broadcom (AVGO), Arista Networks (ANET), Meta Platforms (META), Adobe (ADBE) and CrowdStrike (CRWD). Company Calendar Last Earnings8/06/2026Today10/01/2026Next Earnings (Estimated)11/05/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (5m+) 1-Year History Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 CTMX's financial health is in the Yellow zone, according to TradeSmith. CTMX has been in this zone for over 5 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:CTMX CIK1501989 Webwww.cytomx.com Phone(650) 515-3185Fax650-351-0353Employees69Year Founded2008Price Target and Rating Average Price Target for CytomX Therapeutics$11.90 High Price Target$16.00 Low Price Target$6.00 Potential Upside/Downside+337.5%Consensus RatingModerate Buy Rating Score (0-4)2.83 Research Coverage12 Analysts Profitability EPS (Trailing Twelve Months)($0.50) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$17.37 million Net Margins-435.21% Pretax Margin-433.95% Return on Equity-38.46% Return on Assets-30.33% Debt Debt-to-Equity RatioN/A Current Ratio9.36 Quick Ratio9.36 Sales & Book Value Annual Sales$76.20 million Price / Sales7.78 Cash FlowN/A Price / Cash FlowN/A Book Value$0.58 per share Price / Book4.69Miscellaneous Outstanding Shares217,900,000Free Float209,619,000Market Cap$592.69 million OptionableOptionable Beta2.14 Social Links The Infrastructure's Backbone: 10 Stocks Powering the AI BuildoutThe AI boom extends far beyond the biggest tech names. Discover 10 companies supplying the memory, storage, networking, semiconductor manufacturing, and power infrastructure that make AI possible. Learn where the next wave of AI investment opportunities may emerge—and the key risks investors should watch as the global AI buildout accelerates.Get This Free Report This page (NASDAQ:CTMX) was last updated on 10/1/2026 by MarketBeat.com Staff. From Our PartnersALERT: Drop these 5 stocks before the market opens tomorrow!The Wall Street Journal is already raising the alarm about a potential market crash, and Weiss Ratings researc...Weiss Ratings | SponsoredTrump's New DollarPorter Stansberry says President Trump has signed an executive order initiating what he calls a full U.S. doll...Porter & Company | SponsoredSmall Colorado Company (Backed by Sam Altman) Could Save U.S. Power GridA small Colorado company has secured rights to technology that could prevent the U.S. public power grid from c...Altimetry | SponsoredReady to give options a try? 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