NASDAQ:DSGN Design Therapeutics (DSGN) Stock Price, News & Analysis $12.24 -0.57 (-4.45%) Closing price 09/18/2026 04:00 PM EasternExtended Trading$12.26 +0.02 (+0.12%) As of 09/18/2026 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Design Therapeutics Stock (NASDAQ:DSGN) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Design Therapeutics alerts:Sign Up Key Stats Today's Range$12.24▼$12.8850-Day Range$11.63▼$15.9452-Week Range$5.28▼$17.25Volume2.55 million shsAverage Volume670,156 shsMarket Capitalization$765.98 millionP/E RatioN/ADividend YieldN/APrice Target$16.50Consensus RatingModerate Buy Company Overview Design Therapeutics, Inc. is a clinical-stage biotechnology company developing small-molecule medicines for genetic diseases. The company’s research platform, known as GeneTACs (Gene Targeted Chimeras), is designed to reactivate genes that have been silenced or disrupted by pathogenic genetic changes. Design Therapeutics’ lead programs have focused on diseases associated with nucleotide repeat expansions. Its pipeline has included DT-216, an investigational therapy intended to restore production of the frataxin protein in patients with Friedreich’s ataxia, a rare inherited neurological disorder. The company has also advanced GeneTAC research for additional genetic conditions, including ophthalmic diseases. Founded in 2017 and headquartered in Carlsbad, California, Design Therapeutics conducts drug discovery and clinical development primarily in the United States. The company was co-founded and is led by Pratik Shah, Ph.D., who serves as president and chief executive officer. Its products remain investigational and are subject to clinical and regulatory evaluation.AI Generated. May Contain Errors. Read More Design Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks52nd Percentile Overall ScoreDSGN MarketRank™: Design Therapeutics scored higher than 52% of companies evaluated by MarketBeat, and ranked 447th out of 897 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.6 / 5Analyst RatingModerate Buy Consensus RatingDesign Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.88, and is based on 1 strong buy rating, 6 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialDesign Therapeutics has a consensus price target of $16.50, representing about 34.8% upside from its current price of $12.24.Amount of Analyst CoverageDesign Therapeutics has only been the subject of 1 research reports in the past 90 days.Read more about Design Therapeutics' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Design Therapeutics are expected to decrease in the coming year, from ($1.41) to ($1.73) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Design Therapeutics is -10.37, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Design Therapeutics is -10.37, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioDesign Therapeutics has a P/B Ratio of 3.28. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Design Therapeutics' valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted10.68% of the float of Design Therapeutics has been sold short.Short Interest Ratio / Days to CoverDesign Therapeutics has a short interest ratio ("days to cover") of 8.98.Change versus previous monthShort interest in Design Therapeutics has recently decreased by 6.47%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldDesign Therapeutics does not currently pay a dividend.Dividend GrowthDesign Therapeutics does not have a long track record of dividend growth. News and Social Media2.9 / 5News SentimentN/A News SentimentDesign Therapeutics has a news sentiment score of 0.67. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.56 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 1 news article for Design Therapeutics this week, compared to 2 articles on an average week.Search Interest1 people have searched for DSGN on MarketBeat in the last 30 days. Company Ownership1.3 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Design Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders17.10% of the stock of Design Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions56.64% of the stock of Design Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Design Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. DSGN Stock News HeadlinesDesign Therapeutics, Inc. (NASDAQ:DSGN) Receives $16.50 Average PT from AnalystsSeptember 10, 2026 | americanbankingnews.comDesign Therapeutics to Participate in 2026 Cantor Fitzgerald Global Healthcare ConferenceSeptember 2, 2026 | globenewswire.comMILLIONAIRE MASTERCLASS INVITE: AltucherJames Altucher says Elon Musk is preparing an unprecedented project set to surface on September 25. Altucher is hosting a free masterclass revealing what he says is locked inside a sealed briefcase detailing Musk's plans. Attendees who join early can also access a $1,000 bonus offer included with the presentation.September 20 at 1:00 AM | Paradigm Press (Ad)RBC Capital Sticks to Their Buy Rating for Design Therapeutics (DSGN)August 31, 2026 | theglobeandmail.comWall Street Moves on MAA, Rivian and Design Therapeutics: One Upgrade, One Target Trim and a Biotech on WatchAugust 27, 2026 | 247wallst.comDesign Therapeutics Q2 Net Loss NarrowsAugust 3, 2026 | finance.yahoo.comDesign Therapeutics Provides RESTORE-FA Clinical Development Update and Reports Second Quarter 2026 Financial ResultsAugust 3, 2026 | globenewswire.comA Deeper Dive Into Design TherapeuticsJuly 27, 2026 | seekingalpha.comSee More Headlines DSGN Stock Analysis - Frequently Asked Questions How have DSGN shares performed this year? Design Therapeutics' stock was trading at $9.38 on January 1st, 2026. Since then, DSGN shares have increased by 30.5% and is now trading at $12.24. How were Design Therapeutics' earnings last quarter? Design Therapeutics, Inc. (NASDAQ:DSGN) announced its quarterly earnings data on Monday, August, 3rd. The company reported ($0.32) earnings per share for the quarter, beating analysts' consensus estimates of ($0.34) by $0.02. When did Design Therapeutics IPO? Design Therapeutics (DSGN) raised $228 million in an initial public offering (IPO) on Friday, March 26th 2021. The company issued 12,000,000 shares at a price of $18.00-$20.00 per share. Goldman Sachs, SVB Leerink and Piper Sandler acted as the underwriters for the IPO. Who are Design Therapeutics' major shareholders? Top institutional investors of Design Therapeutics include BlackRock Inc. (4.25%), Trails Edge Capital Partners LP (3.20%), Frazier Life Sciences Management L.P. (2.89%) and Almitas Capital LLC (1.64%). Insiders that own company stock include Rodney W Lappe, John P Schmid, Deepa Prasad and Arsani William. View institutional ownership trends. How do I buy shares of Design Therapeutics? Shares of DSGN stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Design Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Design Therapeutics investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH), iShares Micro-Cap ETF (IWC) and Voyager Therapeutics (VYGR). Company Calendar Last Earnings8/03/2026Today9/20/2026Next Earnings (Estimated)11/04/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (16m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 DSGN's financial health is in the Green zone, according to TradeSmith. DSGN has been in this zone for over 16 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:DSGN CIK1807120 Webwww.designtx.com Phone858-293-4900FaxN/AEmployees55Year Founded2017Price Target and Rating Average Price Target for Design Therapeutics$16.50 High Price Target$21.00 Low Price Target$14.00 Potential Upside/Downside+34.8%Consensus RatingModerate Buy Rating Score (0-4)2.88 Research Coverage8 Analysts Profitability EPS (Trailing Twelve Months)($1.18) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$69.79 million Net MarginsN/A Pretax MarginN/A Return on Equity-34.03% Return on Assets-32.05% Debt Debt-to-Equity RatioN/A Current Ratio18.86 Quick Ratio18.86 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$3.73 per share Price / Book3.28Miscellaneous Outstanding Shares62,580,000Free Float51,880,000Market Cap$765.98 million OptionableOptionable Beta1.66 Social Links 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. Download this report to learn how energy stocks can play a role in your portfolio as the global demand for energy continues to grow.Get This Free Report This page (NASDAQ:DSGN) was last updated on 9/20/2026 by MarketBeat.com Staff. From Our Partners$40,000,000,000,000The national debt just hit 40 trillion dollars, and the U.S. now spends more on interest payments than on its ...American Alternative | SponsoredGold did this exact thing in 1975… [then exploded]In 1975 the Fed raised rates and gold fell 50 percent. Headlines called the gold bull market dead. 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