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Design Therapeutics (DSGN) Competitors

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$15.27 +0.17 (+1.13%)
Closing price 08/18/2026 04:00 PM Eastern
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$15.27 0.00 (0.00%)
As of 08/18/2026 07:30 PM Eastern
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DSGN vs. ALMS, GMTX, CLDX, GRAL, and NAMS

Should you buy Design Therapeutics stock or one of its competitors? Design Therapeutics's main competitors and comparable companies include Alumis (ALMS), Gemini Therapeutics (GMTX), Celldex Therapeutics (CLDX), GRAIL (GRAL), and NewAmsterdam Pharma (NAMS). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Design Therapeutics compare to Alumis?

Alumis (NASDAQ:ALMS) and Design Therapeutics (NASDAQ:DSGN) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, profitability, risk, earnings, valuation, institutional ownership and media sentiment.

Alumis has a beta of -0.69, suggesting that its stock price is 169% less volatile than the broader market. Comparatively, Design Therapeutics has a beta of 1.63, suggesting that its stock price is 63% more volatile than the broader market.

Design Therapeutics has lower revenue, but higher earnings than Alumis. Design Therapeutics is trading at a lower price-to-earnings ratio than Alumis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alumis$24.05M131.89-$243.32M-$3.86N/A
Design TherapeuticsN/AN/A-$69.79M-$1.18N/A

In the previous week, Alumis had 18 more articles in the media than Design Therapeutics. MarketBeat recorded 19 mentions for Alumis and 1 mentions for Design Therapeutics. Design Therapeutics' average media sentiment score of 0.77 beat Alumis' score of -0.13 indicating that Design Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alumis
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Design Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alumis currently has a consensus target price of $40.30, indicating a potential upside of 61.98%. Design Therapeutics has a consensus target price of $16.50, indicating a potential upside of 8.06%. Given Alumis' higher possible upside, equities analysts clearly believe Alumis is more favorable than Design Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alumis
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.75
Design Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

56.6% of Design Therapeutics shares are held by institutional investors. 33.7% of Alumis shares are held by insiders. Comparatively, 17.1% of Design Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Design Therapeutics has a net margin of 0.00% compared to Alumis' net margin of -5,933.46%. Design Therapeutics' return on equity of -34.03% beat Alumis' return on equity.

Company Net Margins Return on Equity Return on Assets
Alumis-5,933.46% -93.15% -74.50%
Design Therapeutics N/A -34.03%-32.05%

Summary

Design Therapeutics beats Alumis on 9 of the 15 factors compared between the two stocks.

How does Design Therapeutics compare to Gemini Therapeutics?

Gemini Therapeutics (NASDAQ:GMTX) and Design Therapeutics (NASDAQ:DSGN) are both healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their analyst recommendations, profitability, media sentiment, institutional ownership, risk, dividends, valuation and earnings.

75.4% of Gemini Therapeutics shares are owned by institutional investors. Comparatively, 56.6% of Design Therapeutics shares are owned by institutional investors. 12.9% of Gemini Therapeutics shares are owned by insiders. Comparatively, 17.1% of Design Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

In the previous week, Design Therapeutics had 1 more articles in the media than Gemini Therapeutics. MarketBeat recorded 1 mentions for Design Therapeutics and 0 mentions for Gemini Therapeutics. Design Therapeutics' average media sentiment score of 0.77 beat Gemini Therapeutics' score of 0.00 indicating that Design Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Gemini Therapeutics Neutral
Design Therapeutics Positive

Design Therapeutics' return on equity of -34.03% beat Gemini Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Gemini TherapeuticsN/A -38.78% -35.88%
Design Therapeutics N/A -34.03%-32.05%

Gemini Therapeutics is trading at a lower price-to-earnings ratio than Design Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Gemini TherapeuticsN/AN/A-$71.87M-$1.00N/A
Design TherapeuticsN/AN/A-$69.79M-$1.18N/A

Gemini Therapeutics has a beta of -0.12, indicating that its stock price is 112% less volatile than the broader market. Comparatively, Design Therapeutics has a beta of 1.63, indicating that its stock price is 63% more volatile than the broader market.

Design Therapeutics has a consensus target price of $16.50, suggesting a potential upside of 8.06%. Given Design Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Design Therapeutics is more favorable than Gemini Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Gemini Therapeutics
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00
Design Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Summary

Design Therapeutics beats Gemini Therapeutics on 12 of the 14 factors compared between the two stocks.

How does Design Therapeutics compare to Celldex Therapeutics?

Design Therapeutics (NASDAQ:DSGN) and Celldex Therapeutics (NASDAQ:CLDX) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their dividends, analyst recommendations, risk, profitability, institutional ownership, media sentiment, valuation and earnings.

Design Therapeutics has a beta of 1.63, indicating that its stock price is 63% more volatile than the broader market. Comparatively, Celldex Therapeutics has a beta of 0.87, indicating that its stock price is 13% less volatile than the broader market.

Design Therapeutics has higher earnings, but lower revenue than Celldex Therapeutics. Design Therapeutics is trading at a lower price-to-earnings ratio than Celldex Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Design TherapeuticsN/AN/A-$69.79M-$1.18N/A
Celldex Therapeutics$1.54M2,131.02-$258.76M-$4.35N/A

Design Therapeutics' return on equity of -34.03% beat Celldex Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Design TherapeuticsN/A -34.03% -32.05%
Celldex Therapeutics N/A -52.35%-47.61%

56.6% of Design Therapeutics shares are owned by institutional investors. 17.1% of Design Therapeutics shares are owned by company insiders. Comparatively, 5.2% of Celldex Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Design Therapeutics presently has a consensus price target of $16.50, suggesting a potential upside of 8.06%. Celldex Therapeutics has a consensus price target of $55.46, suggesting a potential upside of 32.71%. Given Celldex Therapeutics' higher probable upside, analysts clearly believe Celldex Therapeutics is more favorable than Design Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Design Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.86

In the previous week, Celldex Therapeutics had 1 more articles in the media than Design Therapeutics. MarketBeat recorded 2 mentions for Celldex Therapeutics and 1 mentions for Design Therapeutics. Celldex Therapeutics' average media sentiment score of 1.14 beat Design Therapeutics' score of 0.77 indicating that Celldex Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Design Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Celldex Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Design Therapeutics beats Celldex Therapeutics on 8 of the 14 factors compared between the two stocks.

How does Design Therapeutics compare to GRAIL?

GRAIL (NASDAQ:GRAL) and Design Therapeutics (NASDAQ:DSGN) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their analyst recommendations, valuation, dividends, media sentiment, risk, profitability, earnings and institutional ownership.

GRAIL has a beta of 3.24, meaning that its stock price is 224% more volatile than the broader market. Comparatively, Design Therapeutics has a beta of 1.63, meaning that its stock price is 63% more volatile than the broader market.

In the previous week, GRAIL had 6 more articles in the media than Design Therapeutics. MarketBeat recorded 7 mentions for GRAIL and 1 mentions for Design Therapeutics. GRAIL's average media sentiment score of 1.25 beat Design Therapeutics' score of 0.77 indicating that GRAIL is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
GRAIL
5 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Design Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

56.6% of Design Therapeutics shares are owned by institutional investors. 1.8% of GRAIL shares are owned by insiders. Comparatively, 17.1% of Design Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Design Therapeutics has lower revenue, but higher earnings than GRAIL. Design Therapeutics is trading at a lower price-to-earnings ratio than GRAIL, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
GRAIL$147.17M21.52-$408.35M-$9.75N/A
Design TherapeuticsN/AN/A-$69.79M-$1.18N/A

Design Therapeutics has a net margin of 0.00% compared to GRAIL's net margin of -236.95%. GRAIL's return on equity of -15.88% beat Design Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
GRAIL-236.95% -15.88% -14.02%
Design Therapeutics N/A -34.03%-32.05%

GRAIL currently has a consensus price target of $67.78, suggesting a potential downside of 4.39%. Design Therapeutics has a consensus price target of $16.50, suggesting a potential upside of 8.06%. Given Design Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Design Therapeutics is more favorable than GRAIL.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
GRAIL
1 Sell rating(s)
5 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.30
Design Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Summary

Design Therapeutics beats GRAIL on 9 of the 16 factors compared between the two stocks.

How does Design Therapeutics compare to NewAmsterdam Pharma?

NewAmsterdam Pharma (NASDAQ:NAMS) and Design Therapeutics (NASDAQ:DSGN) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their earnings, analyst recommendations, risk, institutional ownership, media sentiment, valuation, dividends and profitability.

NewAmsterdam Pharma has a beta of 0.1, meaning that its stock price is 90% less volatile than the broader market. Comparatively, Design Therapeutics has a beta of 1.63, meaning that its stock price is 63% more volatile than the broader market.

Design Therapeutics has a net margin of 0.00% compared to NewAmsterdam Pharma's net margin of -3,644.21%. Design Therapeutics' return on equity of -34.03% beat NewAmsterdam Pharma's return on equity.

Company Net Margins Return on Equity Return on Assets
NewAmsterdam Pharma-3,644.21% -34.81% -31.50%
Design Therapeutics N/A -34.03%-32.05%

NewAmsterdam Pharma presently has a consensus price target of $49.33, suggesting a potential upside of 81.04%. Design Therapeutics has a consensus price target of $16.50, suggesting a potential upside of 8.06%. Given NewAmsterdam Pharma's stronger consensus rating and higher possible upside, equities analysts clearly believe NewAmsterdam Pharma is more favorable than Design Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
NewAmsterdam Pharma
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
2.93
Design Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

In the previous week, NewAmsterdam Pharma had 2 more articles in the media than Design Therapeutics. MarketBeat recorded 3 mentions for NewAmsterdam Pharma and 1 mentions for Design Therapeutics. NewAmsterdam Pharma's average media sentiment score of 1.49 beat Design Therapeutics' score of 0.77 indicating that NewAmsterdam Pharma is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
NewAmsterdam Pharma
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Design Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Design Therapeutics has lower revenue, but higher earnings than NewAmsterdam Pharma. Design Therapeutics is trading at a lower price-to-earnings ratio than NewAmsterdam Pharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
NewAmsterdam Pharma$7.12M457.43-$203.82M-$2.16N/A
Design TherapeuticsN/AN/A-$69.79M-$1.18N/A

89.9% of NewAmsterdam Pharma shares are held by institutional investors. Comparatively, 56.6% of Design Therapeutics shares are held by institutional investors. 12.7% of NewAmsterdam Pharma shares are held by insiders. Comparatively, 17.1% of Design Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Summary

NewAmsterdam Pharma beats Design Therapeutics on 10 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding DSGN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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DSGN vs. The Competition

MetricDesign TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$928.09M$3.74B$7.06B$13.09B
Dividend YieldN/A3.69%2.56%10.63%
P/E Ratio-12.9411.65270.2824.33
Price / SalesN/A1,355.41676.02125.40
Price / CashN/A44.9028.8838.50
Price / Book4.0917.7311.296.43
Net Income-$69.79M-$12.50M$3.46B$348.18M
7 Day Performance4.16%1.00%0.86%-0.08%
1 Month Performance21.48%3.18%2.56%1.47%
1 Year Performance195.36%59.20%26.82%21.05%

Design Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
DSGN
Design Therapeutics
0.8807 of 5 stars
$15.27
+1.1%
$16.50
+8.1%
+182.8%$928.09MN/AN/A40
ALMS
Alumis
3.1545 of 5 stars
$25.37
-7.8%
$40.30
+58.8%
+413.0%$3.51B$24.05MN/AN/A
GMTX
Gemini Therapeutics
N/A$78.28
+1.1%
N/A+33.7%$3.39BN/AN/A30
CLDX
Celldex Therapeutics
2.7524 of 5 stars
$44.33
+3.2%
$55.46
+25.1%
+70.7%$3.37B$1.54MN/A150
GRAL
GRAIL
0.9109 of 5 stars
$75.48
+0.9%
$67.78
-10.2%
+116.1%$3.34B$147.17MN/A1,360

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This page (NASDAQ:DSGN) was last updated on 8/19/2026 by MarketBeat.com Staff.
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