NASDAQ:PRAX Praxis Precision Medicines (PRAX) Stock Price, News & Analysis $259.86 -3.69 (-1.40%) Closing price 10/9/2026 04:00 PM EasternExtended Trading$259.74 -0.12 (-0.04%) As of 10/9/2026 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Praxis Precision Medicines Stock (NASDAQ:PRAX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get PRAX alerts:Sign Up Key Stats Today's Range$259.00▼$267.8550-Day Range$259.86▼$386.3352-Week Range$50.56▼$392.70Volume517,225 shsAverage Volume510,315 shsMarket Capitalization$7.26 billionP/E RatioN/ADividend YieldN/APrice Target$613.26Consensus RatingModerate Buy Company Overview Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for central nervous system disorders. The company uses insights from human genetics, neuroscience and its Cerebrum™ platform to identify and advance medicines for conditions in which existing treatment options may be limited. Praxis’ pipeline has included investigational treatments for epilepsies and other neurological disorders, including developmental and epileptic encephalopathies, essential tremor and movement-related conditions. Its research programs include small-molecule medicines designed to modulate neuronal ion channels and antisense oligonucleotide therapies intended to address specific genetic drivers of disease. The company’s drug candidates remain subject to clinical testing and regulatory review. Founded in 2015 and headquartered in Boston, Massachusetts, Praxis conducts research and clinical development activities through collaborations and studies in the United States and other regions. The company is led by President and Chief Executive Officer Marcio Souza.AI Generated. May Contain Errors. Read More Praxis Precision Medicines Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks55th Percentile Overall ScorePRAX MarketRank™: Praxis Precision Medicines scored higher than 55% of companies evaluated by MarketBeat, and ranked 453rd out of 883 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.5 / 5Analyst RatingModerate Buy Consensus RatingPraxis Precision Medicines has received a consensus rating of Moderate Buy. The company's average rating score is 2.95, and is based on 3 strong buy ratings, 15 buy ratings, no hold ratings, and 2 sell ratings.Upside PotentialPraxis Precision Medicines has a consensus price target of $613.26, representing about 136.0% upside from its current price of $259.86.Amount of Analyst CoveragePraxis Precision Medicines has been the subject of 9 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Praxis Precision Medicines' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Praxis Precision Medicines are expected to grow in the coming year, from ($13.90) to ($11.33) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Praxis Precision Medicines is -20.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Praxis Precision Medicines is -20.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioPraxis Precision Medicines has a P/B Ratio of 7.46. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Praxis Precision Medicines' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted15.46% of the float of Praxis Precision Medicines has been sold short.Short Interest Ratio / Days to CoverPraxis Precision Medicines has a short interest ratio ("days to cover") of 7.16.Change versus previous monthShort interest in Praxis Precision Medicines has recently increased by 10.34%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldPraxis Precision Medicines does not currently pay a dividend.Dividend GrowthPraxis Precision Medicines does not have a long track record of dividend growth. News and Social Media2.2 / 5News Sentiment0.44 News SentimentPraxis Precision Medicines has a news sentiment score of 0.44. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.63 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 7 news articles for Praxis Precision Medicines this week, compared to 7 articles on an average week.Search Interest7 people have searched for PRAX on MarketBeat in the last 30 days. This is an increase of 133% compared to the previous 30 days.MarketBeat FollowsOnly 3 people have added Praxis Precision Medicines to their MarketBeat watchlist in the last 30 days. This is a decrease of -57% compared to the previous 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Praxis Precision Medicines insiders have not sold or bought any company stock.Percentage Held by Insiders3.00% of the stock of Praxis Precision Medicines is held by insiders.Percentage Held by Institutions67.84% of the stock of Praxis Precision Medicines is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Praxis Precision Medicines' insider trading history. Receive PRAX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Praxis Precision Medicines and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. PRAX Stock News HeadlinesPraxis Precision Medicines (NASDAQ:PRAX) Stock Rating Reaffirmed as "Buy" by HC WainwrightOctober 8 at 2:30 AM | americanbankingnews.comPraxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)October 2, 2026 | globenewswire.comA letter from Shannon StansberryPorter Stansberry nearly canceled the entire project. When he first saw the claimed returns - only one down year in nearly two decades and total gains of almost 2,000% - his immediate reaction was disbelief. It took a trusted friend's personal vouching for Emmet Savage and a face-to-face trip to Ireland to change his mind. The full documentary, Investigating Project Prophet, is now live.October 10 at 1:00 AM | Porter & Company (Ad)Head-To-Head Comparison: Actinium Pharmaceuticals (NYSE:ATNM) versus Praxis Precision Medicines (NASDAQ:PRAX)October 2, 2026 | americanbankingnews.comPraxis Precision Medicines Inc (PRAX)September 19, 2026 | in.investing.comPraxis Precision Medicines: Still Potential Upside After Huge Rally (Rating Upgrade)September 12, 2026 | seekingalpha.comPraxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)September 3, 2026 | globenewswire.comS&P 500 Futures Drop in Premarket Trading; Praxis Precision Meds, Science Applications LeadAugust 31, 2026 | barrons.comSee More Headlines PRAX Stock Analysis - Frequently Asked Questions How have PRAX shares performed this year? Praxis Precision Medicines' stock was trading at $294.74 at the beginning of 2026. Since then, PRAX shares have decreased by 11.8% and is now trading at $259.86. How were Praxis Precision Medicines' earnings last quarter? Praxis Precision Medicines, Inc. (NASDAQ:PRAX) issued its earnings results on Thursday, August, 6th. The company reported ($2.87) earnings per share for the quarter, beating analysts' consensus estimates of ($3.67) by $0.80. Read the conference call transcript. When did Praxis Precision Medicines' stock split? Praxis Precision Medicines's stock reverse split on Wednesday, November 29th 2023.The 1-15 reverse split was announced on Wednesday, November 29th 2023. The number of shares owned by shareholders was adjusted after the market closes on Wednesday, November 29th 2023. An investor that had 100 shares of stock prior to the reverse split would have 7 shares after the split. When did Praxis Precision Medicines IPO? Praxis Precision Medicines (PRAX) raised $170 million in an initial public offering (IPO) on Friday, October 16th 2020. The company issued 10,000,000 shares at a price of $16.00-$18.00 per share. Cowen, Evercore ISI, Piper Sandler and Wedbush PacGrow acted as the underwriters for the IPO and Blackstone Capital Markets was co-manager. Who are Praxis Precision Medicines' major shareholders? Praxis Precision Medicines' top institutional investors include GAMMA Investing LLC. Insiders that own company stock include Alex Nemiroff, Lauren Mastrocola and Jill Desimone. View institutional ownership trends. How do I buy shares of Praxis Precision Medicines? Shares of PRAX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Praxis Precision Medicines own? Based on aggregate information from My MarketBeat watchlists, some other companies that Praxis Precision Medicines investors own include NVIDIA (NVDA), Broadcom (AVGO), Meta Platforms (META), Advanced Micro Devices (AMD), Adobe (ADBE), Arista Networks (ANET) and ServiceNow (NOW). Company Calendar Last Earnings8/06/2026Today10/10/2026Next Earnings (Estimated)11/09/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (12m+) 1-Year History Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 PRAX's financial health is in the Green zone, according to TradeSmith. PRAX has been in this zone for over 12 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:PRAX CIK1689548 Webwww.praxismedicines.com Phone617-300-8460FaxN/AEmployees168Year Founded2015Price Target and Rating Average Price Target for Praxis Precision Medicines$613.26 High Price Target$1,201.00 Low Price Target$162.00 Potential Upside/Downside+136.0%Consensus RatingModerate Buy Rating Score (0-4)2.95 Research Coverage20 Analysts Profitability EPS (Trailing Twelve Months)($12.93) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$303.27 million Net MarginsN/A Pretax MarginN/A Return on Equity-34.15% Return on Assets-32.42% Debt Debt-to-Equity RatioN/A Current Ratio15.73 Quick Ratio15.73 Sales & Book Value Annual Sales$8.55 million Price / Sales848.57 Cash FlowN/A Price / Cash FlowN/A Book Value$34.85 per share Price / Book7.46Miscellaneous Outstanding Shares27,920,000Free Float27,082,000Market Cap$7.26 billion OptionableOptionable Beta2.79 Social Links Options Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. Click the link below to get your free copy.Get This Free Report This page (NASDAQ:PRAX) was last updated on 10/10/2026 by MarketBeat.com Staff. 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