CRISPR Therapeutics AG (NASDAQ: CRSP) is a biotechnology company focused on developing gene-editing medicines based on CRISPR/Cas9 technology. The company aims to treat serious diseases by precisely modifying genetic material in patients’ cells, with research programs spanning hematology, oncology, autoimmune diseases, and regenerative medicine.
Its lead product, CASGEVY (exagamglogene autotemcel), is a CRISPR/Cas9-based cell therapy developed with Vertex Pharmaceuticals. CASGEVY is approved in multiple markets, including the United States, United Kingdom, and European Union, for certain patients with sickle cell disease and transfusion-dependent beta thalassemia. The therapy uses a patient’s own blood stem cells, which are edited outside the body and then reinfused.
Founded in 2013, CRISPR Therapeutics conducts research and clinical development internationally, with operations and activities in North America and Europe. The company was co-founded by Emmanuelle Charpentier, Rodger Novak, and other scientists, and is led by Chief Executive Officer Samarth Kulkarni.
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