Apellis Pharmaceuticals (APLS) Competitors $17.43 -0.97 (-5.27%) Closing price 06/27/2025 04:00 PM EasternExtended Trading$17.92 +0.50 (+2.84%) As of 06/27/2025 07:50 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock APLS vs. BPMC, BBIO, ROIV, VRNA, RVMD, ELAN, LEGN, GRFS, TLX, and TGTXShould you be buying Apellis Pharmaceuticals stock or one of its competitors? The main competitors of Apellis Pharmaceuticals include Blueprint Medicines (BPMC), BridgeBio Pharma (BBIO), Roivant Sciences (ROIV), Verona Pharma (VRNA), Revolution Medicines (RVMD), Elanco Animal Health (ELAN), Legend Biotech (LEGN), Grifols (GRFS), Telix Pharmaceuticals Limited American Depositary Shares (TLX), and TG Therapeutics (TGTX). These companies are all part of the "pharmaceutical products" industry. Apellis Pharmaceuticals vs. Its Competitors Blueprint Medicines BridgeBio Pharma Roivant Sciences Verona Pharma Revolution Medicines Elanco Animal Health Legend Biotech Grifols Telix Pharmaceuticals Limited American Depositary Shares TG Therapeutics Apellis Pharmaceuticals (NASDAQ:APLS) and Blueprint Medicines (NASDAQ:BPMC) are both mid-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their dividends, media sentiment, risk, earnings, institutional ownership, analyst recommendations, valuation and profitability. Does the media prefer APLS or BPMC? In the previous week, Blueprint Medicines had 5 more articles in the media than Apellis Pharmaceuticals. MarketBeat recorded 7 mentions for Blueprint Medicines and 2 mentions for Apellis Pharmaceuticals. Blueprint Medicines' average media sentiment score of 1.34 beat Apellis Pharmaceuticals' score of 0.93 indicating that Blueprint Medicines is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Apellis Pharmaceuticals 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Blueprint Medicines 5 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has better earnings and valuation, APLS or BPMC? Blueprint Medicines has lower revenue, but higher earnings than Apellis Pharmaceuticals. Blueprint Medicines is trading at a lower price-to-earnings ratio than Apellis Pharmaceuticals, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioApellis Pharmaceuticals$781.37M2.80-$197.88M-$1.79-9.74Blueprint Medicines$508.82M16.26-$67.09M-$2.47-51.87 Do insiders and institutionals hold more shares of APLS or BPMC? 96.3% of Apellis Pharmaceuticals shares are held by institutional investors. 6.5% of Apellis Pharmaceuticals shares are held by insiders. Comparatively, 4.2% of Blueprint Medicines shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term. Is APLS or BPMC more profitable? Blueprint Medicines has a net margin of -27.70% compared to Apellis Pharmaceuticals' net margin of -28.83%. Blueprint Medicines' return on equity of -64.60% beat Apellis Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Apellis Pharmaceuticals-28.83% -99.19% -25.35% Blueprint Medicines -27.70%-64.60%-17.22% Which has more risk and volatility, APLS or BPMC? Apellis Pharmaceuticals has a beta of 0.68, suggesting that its share price is 32% less volatile than the S&P 500. Comparatively, Blueprint Medicines has a beta of 0.84, suggesting that its share price is 16% less volatile than the S&P 500. Do analysts prefer APLS or BPMC? Apellis Pharmaceuticals presently has a consensus price target of $40.05, suggesting a potential upside of 129.79%. Blueprint Medicines has a consensus price target of $128.06, suggesting a potential downside of 0.04%. Given Apellis Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Apellis Pharmaceuticals is more favorable than Blueprint Medicines.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Apellis Pharmaceuticals 0 Sell rating(s) 9 Hold rating(s) 11 Buy rating(s) 1 Strong Buy rating(s) 2.62Blueprint Medicines 0 Sell rating(s) 17 Hold rating(s) 4 Buy rating(s) 1 Strong Buy rating(s) 2.27 SummaryApellis Pharmaceuticals and Blueprint Medicines tied by winning 8 of the 16 factors compared between the two stocks. Get Apellis Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for APLS and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding APLS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart APLS vs. The Competition Export to ExcelMetricApellis PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$2.19B$2.84B$5.47B$8.93BDividend YieldN/A2.48%5.32%4.14%P/E Ratio-9.7421.0326.2119.67Price / Sales2.80281.84387.56105.07Price / CashN/A42.8636.4056.84Price / Book9.477.207.875.43Net Income-$197.88M-$55.15M$3.16B$249.20M7 Day Performance-1.47%0.76%3.10%3.99%1 Month Performance0.11%4.39%4.62%4.82%1 Year Performance-54.56%-0.74%31.74%17.00% Apellis Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)APLSApellis Pharmaceuticals4.5105 of 5 stars$17.43-5.3%$40.05+129.8%-54.6%$2.19B$781.37M-9.74770BPMCBlueprint Medicines1.7445 of 5 stars$128.25+0.2%$129.35+0.9%+18.9%$8.28B$562.12M-118.75640Positive NewsHigh Trading VolumeBBIOBridgeBio Pharma4.6845 of 5 stars$41.14+3.4%$57.36+39.4%+77.1%$7.81B$127.42M-14.44400News CoverageAnalyst ForecastInsider TradeROIVRoivant Sciences2.0382 of 5 stars$11.08-2.1%$17.50+57.9%+7.8%$7.53B$29.05M-73.86860Insider TradeOptions VolumeVRNAVerona Pharma1.7062 of 5 stars$92.70+0.5%$87.44-5.7%+548.8%$7.52B$118.54M-48.2830RVMDRevolution Medicines4.5245 of 5 stars$39.77-2.0%$67.08+68.7%-4.9%$7.41B$742K-11.08250News CoveragePositive NewsAnalyst ForecastAnalyst RevisionELANElanco Animal Health2.2932 of 5 stars$14.00+1.4%$15.17+8.3%-0.8%$6.95B$4.43B35.019,800News CoverageAnalyst UpgradeLEGNLegend Biotech2.3957 of 5 stars$35.84-2.7%$76.20+112.6%-21.8%$6.59B$728.30M-37.731,070Positive NewsGRFSGrifols4.047 of 5 stars$9.09+2.5%N/A+40.5%$6.25B$7.21B7.7726,300Analyst DowngradeTLXTelix Pharmaceuticals Limited American Depositary SharesN/A$16.74+4.0%$22.00+31.4%N/A$5.66B$783.21M0.00N/AGap DownTGTXTG Therapeutics3.6326 of 5 stars$35.63-1.1%$40.80+14.5%+106.4%$5.66B$386.39M-356.26290News Coverage Related Companies and Tools Related Companies BPMC Alternatives BBIO Alternatives ROIV Alternatives VRNA Alternatives RVMD Alternatives ELAN Alternatives LEGN Alternatives GRFS Alternatives TLX Alternatives TGTX Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:APLS) was last updated on 6/29/2025 by MarketBeat.com Staff From Our PartnersTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans...Paradigm Press | Sponsored3..2..1.. AI 2.0 ignition (don’t sleep on this)I just put together an urgent new presentation that you need to see right away. In short: I believe we are...Timothy Sykes | SponsoredElon’s NEXT Big IPO?Cancel your internet TODAY!? Take your latest internet bill and light it on fire… then count the seconds it...Banyan Hill Publishing | SponsoredCrypto Is Pumping Again – Now Comes the Real OpportunityThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredSilicon Valley Gold RushA new technology has sparked a modern-day gold rush in Silicon Valley. OpenAI’s Sam Altman invested $375M. Bil...Stansberry Research | SponsoredThe Robotics Revolution has arrived … and one $7 stock could take off as a result.Robots aren't coming to America in 2025. They are already here. Oxford Economics says, "The Robotics Rev...Weiss Ratings | SponsoredTrump’s true trade war strategyThe media and financial pundits are all misreading Trump’s actions. They think Trump wants to make Canada t...Porter & Company | SponsoredWhy July 22nd Could Mean Big Changes for Social SecurityIn a stunning move, President Trump has authorized an AI-led transformation of federal agencies, including Soc...Altimetry | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added ten stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Apellis Pharmaceuticals, Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Apellis Pharmaceuticals With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.