Arcturus Therapeutics (ARCT) Stock Price, News & Analysis

Company Overview

Arcturus Therapeutics Holdings Inc. is a clinical-stage biotechnology company dedicated to developing messenger RNA (mRNA) medicines that address a range of diseases. The company leverages its proprietary STARR® mRNA platform to enable precise control over mRNA expression, supported by its lipid nanoparticle delivery technology, LUNAR®. Arcturus’s approach is designed to address both therapeutic and prophylactic applications, with an emphasis on vaccines and treatments for rare genetic and infectious diseases.

The company’s pipeline includes ARCT-810, an mRNA therapeutic candidate for phenylketonuria (PKU), and ARCT-021 (also known as LUNAR-COV19), a COVID-19 vaccine candidate developed in collaboration with Duke-NUS Medical School in Singapore. Additional preclinical programs are directed toward addressing other metabolic disorders and infectious diseases. Arcturus’s research and development efforts focus on leveraging mRNA’s capacity for rapid design and production, aiming to reduce development timelines compared with traditional biologics.

Headquartered in San Diego, California, Arcturus maintains research and manufacturing facilities both in the United States and in Singapore, reflecting its commitment to global collaboration and supply chain resilience. The Singapore facility supports the company’s vaccine development programs and provides clinical-scale manufacturing capabilities to meet regulatory requirements in multiple jurisdictions.

Since going public in 2018, Arcturus has been led by Chief Executive Officer Joseph E. Payne, who brings experience from several biotechnology and pharmaceutical roles. Under his leadership, the company has forged partnerships with academic institutions and contract manufacturing organizations to advance its clinical programs. Arcturus continues to explore new applications of its mRNA platform through collaborations and licensing agreements aimed at expanding its pipeline and demonstrating the versatility of mRNA-based therapeutics.

Key Stats

• Today's Range: $20.40 to $22.13
• 50-Day Range: $11.39 to $22.56
• 52-Week Range: $8.04 to $23.59
• Volume: 647,078 shs
• Average Volume: 929,917 shs
• Market Capitalization: $561.13 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $50.57
• Consensus Rating: Moderate Buy

Arcturus Therapeutics Stock Analysis - MarketRank™

Arcturus Therapeutics scored higher than 72% of companies evaluated by MarketBeat, and ranked 279th out of 950 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.5 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

Arcturus Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.90, and is based on 8 buy ratings, no hold ratings, and 1 sell rating.

Upside Potential

Arcturus Therapeutics has a consensus price target of $50.57, representing about 144.8% upside from its current price of $20.66.

Amount of Analyst Coverage

Arcturus Therapeutics has been the subject of 6 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Arcturus Therapeutics are expected to grow in the coming year, from ($2.22) to ($0.78) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Arcturus Therapeutics is -9.26, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Arcturus Therapeutics is -9.26, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Arcturus Therapeutics has a P/B Ratio of 2.32. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

20.68% of the float of Arcturus Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Arcturus Therapeutics has a short interest ratio ("days to cover") of 7.8.

Change versus previous month

Short interest in Arcturus Therapeutics has recently decreased by 13.61%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Arcturus Therapeutics does not currently pay a dividend.

Dividend Growth

Arcturus Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

20.68% of the float of Arcturus Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Arcturus Therapeutics has a short interest ratio ("days to cover") of 7.8.

Change versus previous month

Short interest in Arcturus Therapeutics has recently decreased by 13.61%, indicating that investor sentiment is improving significantly.

News and Social Media

• Score: 3.4 / 5
• News Sentiment: 1.07

News Sentiment

Arcturus Therapeutics has a news sentiment score of 1.07. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.48 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 3 news articles for Arcturus Therapeutics this week, compared to 4 articles on an average week.

Search Interest

40 people have searched for ARCT on MarketBeat in the last 30 days. This is an increase of 208% compared to the previous 30 days.

MarketBeat Follows

3 people have added Arcturus Therapeutics to their MarketBeat watchlist in the last 30 days. This is an increase of 50% compared to the previous 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Arcturus Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

16.60% of the stock of Arcturus Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

94.54% of the stock of Arcturus Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

ARCT Stock Analysis - Frequently Asked Questions

How have ARCT shares performed this year?

Arcturus Therapeutics' stock was trading at $16.97 at the start of the year. Since then, ARCT stock has increased by 21.7% and is now trading at $20.66.

How were Arcturus Therapeutics' earnings last quarter?

Arcturus Therapeutics Holdings Inc. (NASDAQ:ARCT) posted its quarterly earnings results on Monday, August, 11th. The biotechnology company reported ($0.34) earnings per share (EPS) for the quarter, beating analysts' consensus estimates of ($1.11) by $0.77. The biotechnology company earned $28.30 million during the quarter, compared to the consensus estimate of $17.64 million. Arcturus Therapeutics had a negative trailing twelve-month return on equity of 24.87% and a negative net margin of 49.26%.
Read the conference call transcript.

Who are Arcturus Therapeutics' major shareholders?

Top institutional shareholders of Arcturus Therapeutics include Green Alpha Advisors LLC (0.08%). Insiders that own company stock include Pad Chivukula, Magda Marquet and Keith C Kummerfeld.
View institutional ownership trends.

How do I buy shares of Arcturus Therapeutics?

Shares of ARCT stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Arcturus Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Arcturus Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Broadcom (AVGO), Advanced Micro Devices (AMD), Adobe (ADBE), ServiceNow (NOW) and CrowdStrike (CRWD).

Company Calendar

• Last Earnings: 8/11/2025
• Today: 10/19/2025
• Next Earnings (Estimated): 11/06/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:ARCT
• CIK: 1410997
• Web: www.arcturusrx.com
• Phone: (858) 900-2660
• Fax: N/A
• Employees: 180
• Year Founded: 2013

Price Target and Rating

• Average Price Target for Arcturus Therapeutics: $50.57
• High Price Target: $66.00
• Low Price Target: $35.00
• Potential Upside/Downside: +144.8%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.90
• Research Coverage: 10 Analysts

Profitability

• EPS (Trailing Twelve Months): ($2.23)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$80.94 million
• Net Margins: -49.26%
• Pretax Margin: -49.44%
• Return on Equity: -24.87%
• Return on Assets: -17.75%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 5.90
• Quick Ratio: 5.90

Sales & Book Value

• Annual Sales: $152.31 million
• Price / Sales: 3.68
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $8.90 per share
• Price / Book: 2.32

Miscellaneous

• Outstanding Shares: 27,160,000
• Free Float: 22,647,000
• Market Cap: $561.13 million
• Optionable: Optionable
• Beta: 2.39