NASDAQ:AXSM Axsome Therapeutics (AXSM) Stock Price, News & Analysis $207.78 -6.50 (-3.03%) Closing price 09/18/2026 04:00 PM EasternExtended Trading$207.16 -0.62 (-0.30%) As of 09/18/2026 07:46 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Axsome Therapeutics Stock (NASDAQ:AXSM) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Axsome Therapeutics alerts:Sign Up Key Stats Today's Range$206.92▼$213.2750-Day Range$198.52▼$241.5352-Week Range$114.91▼$260.19Volume869,284 shsAverage Volume556,852 shsMarket Capitalization$10.88 billionP/E RatioN/ADividend YieldN/APrice Target$267.60Consensus RatingModerate Buy Company Overview Axsome Therapeutics, Inc. is a biopharmaceutical company focused on developing and commercializing therapies for central nervous system (CNS) disorders. The company’s research programs address conditions with substantial unmet medical needs, including depression, migraine, narcolepsy, excessive daytime sleepiness, agitation associated with Alzheimer’s disease, and other neurological or psychiatric disorders. Axsome’s commercial portfolio includes Auvelity, an oral medicine approved in the United States for the treatment of major depressive disorder in adults. The company also markets Sunosi (solriamfetol) in the United States for excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea. Axsome obtained rights to Sunosi from Jazz Pharmaceuticals. The company is advancing additional product candidates, including therapies being evaluated for Alzheimer’s disease agitation, migraine, narcolepsy, and other CNS conditions. Axsome was founded in 2012 and is headquartered in New York. Its founder and chief executive officer is Herriot Tabuteau, M.D.AI Generated. May Contain Errors. Read More Axsome Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks80th Percentile Overall ScoreAXSM MarketRank™: Axsome Therapeutics scored higher than 80% of companies evaluated by MarketBeat, and ranked 135th out of 897 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.5 / 5Analyst RatingModerate Buy Consensus RatingAxsome Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.91, and is based on 2 strong buy ratings, 17 buy ratings, 2 hold ratings, and 1 sell rating.Upside PotentialAxsome Therapeutics has a consensus price target of $267.60, representing about 28.8% upside from its current price of $207.78.Amount of Analyst CoverageAxsome Therapeutics has been the subject of 12 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Axsome Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Axsome Therapeutics are expected to grow in the coming year, from ($2.80) to $4.06 per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Axsome Therapeutics is -55.41, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Axsome Therapeutics is -55.41, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioAxsome Therapeutics has a P/B Ratio of 118.73. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Axsome Therapeutics' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted7.41% of the float of Axsome Therapeutics has been sold short.Short Interest Ratio / Days to CoverAxsome Therapeutics has a short interest ratio ("days to cover") of 5.83.Change versus previous monthShort interest in Axsome Therapeutics has recently decreased by 3.91%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAxsome Therapeutics does not currently pay a dividend.Dividend GrowthAxsome Therapeutics does not have a long track record of dividend growth. News and Social Media4.3 / 5News Sentiment0.80 News SentimentAxsome Therapeutics has a news sentiment score of 0.80. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.56 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 15 news articles for Axsome Therapeutics this week, compared to 9 articles on an average week.Search Interest18 people have searched for AXSM on MarketBeat in the last 30 days. This is an increase of 200% compared to the previous 30 days.MarketBeat Follows8 people have added Axsome Therapeutics to their MarketBeat watchlist in the last 30 days. This is an increase of 14% compared to the previous 30 days. Company Ownership2.1 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Axsome Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $24,557,062.00 in company stock.Percentage Held by Insiders20.60% of the stock of Axsome Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions81.49% of the stock of Axsome Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Axsome Therapeutics' insider trading history. Receive AXSM Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Axsome Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. AXSM Stock News HeadlinesPiper Sandler Reiterates "Overweight" Rating for Axsome Therapeutics (NASDAQ:AXSM)September 20 at 1:24 AM | americanbankingnews.comPiper Sandler Sticks to Its Buy Rating for Axsome Therapeutics (AXSM)September 19 at 5:25 PM | theglobeandmail.comTrump goes "all-in" on Grand Canyon energy breakthroughA drilling crew near the Grand Canyon uncovered a clean energy well producing nearly eight times the output of Saudi Arabia's largest oil field, with potential to last two million years. 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One company controls the entire supply chain behind this discovery.September 20 at 1:00 AM | Behind the Markets (Ad)Axsome Therapeutics vs. Moderna: Which Healthcare Stock Is a Better Buy in 2026?September 18 at 3:24 PM | fool.comAxsome's Auvelity Launch Shows Early Strength in Alzheimer's Agitation, RBC SaysSeptember 18 at 3:24 PM | finance.yahoo.comIs Axsome Therapeutics a Buy on the Dip?September 18 at 2:45 AM | fool.comAxsome Therapeutics Presents Ten Posters Exemplifying its Innovative Psychiatry and Neurology Portfolio at Psych Congress 2026September 17 at 7:00 AM | globenewswire.comMark Jacobson Sells 10,000 Shares of Axsome Therapeutics (NASDAQ:AXSM) StockSeptember 4, 2026 | insidertrades.comSee More Headlines AXSM Stock Analysis - Frequently Asked Questions How have AXSM shares performed this year? Axsome Therapeutics' stock was trading at $182.64 at the beginning of the year. Since then, AXSM stock has increased by 13.8% and is now trading at $207.78. How were Axsome Therapeutics' earnings last quarter? Axsome Therapeutics, Inc. (NASDAQ:AXSM) posted its quarterly earnings data on Monday, August, 10th. The company reported ($0.99) earnings per share for the quarter, missing the consensus estimate of ($0.89) by $0.10. The company earned $218.38 million during the quarter, compared to analyst estimates of $221.11 million. Axsome Therapeutics had a negative trailing twelve-month return on equity of 265.55% and a negative net margin of 24.68%. Read the conference call transcript. When did Axsome Therapeutics IPO? Axsome Therapeutics (AXSM) raised $52 million in an initial public offering (IPO) on Thursday, November 19th 2015. The company issued 4,300,000 shares at a price of $11.00-$13.00 per share. Ladenburg Thalmann and Cantor Fitzgerald & Co. served as the underwriters for the IPO and Brean Capital was co-manager. Who are Axsome Therapeutics' major shareholders? Axsome Therapeutics' top institutional investors include BlackRock Inc. (6.03%), Wellington Management Group LLP (1.25%), Assenagon Asset Management S.A. (0.88%) and Bank of America Corp DE (0.86%). Insiders that own company stock include Roger Jeffs, Nick Pizzie, Mark Coleman, Mark E Saad, Mark L Jacobson, Ari Maizel, Herriot Tabuteau and Hunter R Murdock. View institutional ownership trends. How do I buy shares of Axsome Therapeutics? Shares of AXSM stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Axsome Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Axsome Therapeutics investors own include Humana (HUM), American Water Works (AWK), Voyager Therapeutics (VYGR), Waste Connections (WCN), The RMR Group (RMR), DiamondRock Hospitality (DRH) and Company Calendar Last Earnings8/10/2026Today9/20/2026Next Earnings (Estimated)11/02/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (4d) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 As of 4 days ago, AXSM's financial health entered the Green zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Pharmaceuticals Sub-IndustryPharmaceuticals Current SymbolNASDAQ:AXSM CIK1579428 Webaxsome.com Phone(212) 332-3241Fax212-320-0245Employees925Year Founded2012Price Target and Rating Average Price Target for Axsome Therapeutics$267.60 High Price Target$380.00 Low Price Target$179.00 Potential Upside/Downside+28.8%Consensus RatingModerate Buy Rating Score (0-4)2.91 Research Coverage22 Analysts Profitability EPS (Trailing Twelve Months)($3.75) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$183.17 million Net Margins-24.68% Pretax Margin-24.61% Return on Equity-265.55% Return on Assets-28.10% Debt Debt-to-Equity Ratio1.52 Current Ratio1.43 Quick Ratio1.34 Sales & Book Value Annual Sales$638.50 million Price / Sales17.05 Cash FlowN/A Price / Cash FlowN/A Book Value$1.75 per share Price / Book118.73Miscellaneous Outstanding Shares52,380,000Free Float41,591,000Market Cap$10.88 billion OptionableOptionable Beta0.71 Social Links 7 Stocks That Could Lead the Next Market BoomTesla, Nvidia, and Google helped shape the last era of market growth, but the next wave could come from a new group of companies. 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