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Clene (CLNN) Competitors

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$3.86 -0.02 (-0.52%)
Closing price 10/9/2026 04:00 PM Eastern
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$3.86 0.00 (0.00%)
As of 10/9/2026 07:59 PM Eastern
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CLNN vs. SLGL, ACOG, DERM, ZNTL, and CRDL

Should you buy Clene stock or one of its competitors? Clene's main competitors and comparable companies include Sol-Gel Technologies (SLGL), Alpha Cognition (ACOG), Journey Medical (DERM), Zentalis Pharmaceuticals (ZNTL), and Cardiol Therapeutics (CRDL). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "pharmaceuticals" industry.

How does Clene compare to Sol-Gel Technologies?

Clene (NASDAQ:CLNN) and Sol-Gel Technologies (NASDAQ:SLGL) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their risk, institutional ownership, media sentiment, analyst recommendations, earnings, profitability, dividends and valuation.

23.3% of Clene shares are owned by institutional investors. Comparatively, 26.2% of Sol-Gel Technologies shares are owned by institutional investors. 28.3% of Clene shares are owned by company insiders. Comparatively, 66.5% of Sol-Gel Technologies shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Clene has a beta of 0.91, indicating that its share price is 9% less volatile than the broader market. Comparatively, Sol-Gel Technologies has a beta of 1.14, indicating that its share price is 14% more volatile than the broader market.

In the previous week, Sol-Gel Technologies had 8 more articles in the media than Clene. MarketBeat recorded 9 mentions for Sol-Gel Technologies and 1 mentions for Clene. Sol-Gel Technologies' average media sentiment score of 0.76 beat Clene's score of 0.00 indicating that Sol-Gel Technologies is being referred to more favorably in the news media.

Company Overall Sentiment
Clene Neutral
Sol-Gel Technologies Positive

Sol-Gel Technologies has a net margin of -910.14% compared to Clene's net margin of -20,063.96%. Clene's return on equity of 0.00% beat Sol-Gel Technologies' return on equity.

Company Net Margins Return on Equity Return on Assets
Clene-20,063.96% N/A -137.04%
Sol-Gel Technologies -910.14%-44.05%-36.96%

Sol-Gel Technologies has higher revenue and earnings than Clene. Sol-Gel Technologies is trading at a lower price-to-earnings ratio than Clene, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Clene$200K250.71-$26.17M-$3.50N/A
Sol-Gel Technologies$19.39M12.10-$6.13M-$5.64N/A

Clene currently has a consensus target price of $34.00, suggesting a potential upside of 780.83%. Sol-Gel Technologies has a consensus target price of $197.50, suggesting a potential upside of 175.18%. Given Clene's stronger consensus rating and higher possible upside, equities analysts clearly believe Clene is more favorable than Sol-Gel Technologies.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Clene
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71
Sol-Gel Technologies
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

Summary

Sol-Gel Technologies beats Clene on 10 of the 17 factors compared between the two stocks.

How does Clene compare to Alpha Cognition?

Alpha Cognition (NASDAQ:ACOG) and Clene (NASDAQ:CLNN) are both small-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their profitability, media sentiment, dividends, risk, analyst recommendations, institutional ownership, valuation and earnings.

Alpha Cognition has higher revenue and earnings than Clene. Alpha Cognition is trading at a lower price-to-earnings ratio than Clene, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alpha Cognition$15.26M12.90-$20.67M-$1.10N/A
Clene$200K250.71-$26.17M-$3.50N/A

In the previous week, Alpha Cognition had 4 more articles in the media than Clene. MarketBeat recorded 5 mentions for Alpha Cognition and 1 mentions for Clene. Alpha Cognition's average media sentiment score of 0.59 beat Clene's score of 0.00 indicating that Alpha Cognition is being referred to more favorably in the media.

Company Overall Sentiment
Alpha Cognition Positive
Clene Neutral

Alpha Cognition has a beta of 2.32, suggesting that its stock price is 132% more volatile than the broader market. Comparatively, Clene has a beta of 0.91, suggesting that its stock price is 9% less volatile than the broader market.

Alpha Cognition has a net margin of -153.61% compared to Clene's net margin of -20,063.96%. Clene's return on equity of 0.00% beat Alpha Cognition's return on equity.

Company Net Margins Return on Equity Return on Assets
Alpha Cognition-153.61% -54.60% -43.47%
Clene -20,063.96%N/A -137.04%

23.3% of Clene shares are held by institutional investors. 8.6% of Alpha Cognition shares are held by insiders. Comparatively, 28.3% of Clene shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Alpha Cognition currently has a consensus target price of $18.00, suggesting a potential upside of 99.12%. Clene has a consensus target price of $34.00, suggesting a potential upside of 780.83%. Given Clene's higher possible upside, analysts plainly believe Clene is more favorable than Alpha Cognition.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alpha Cognition
0 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
3.00
Clene
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

Summary

Alpha Cognition beats Clene on 9 of the 16 factors compared between the two stocks.

How does Clene compare to Journey Medical?

Clene (NASDAQ:CLNN) and Journey Medical (NASDAQ:DERM) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their earnings, media sentiment, valuation, institutional ownership, risk, profitability, analyst recommendations and dividends.

23.3% of Clene shares are owned by institutional investors. Comparatively, 7.3% of Journey Medical shares are owned by institutional investors. 28.3% of Clene shares are owned by company insiders. Comparatively, 14.5% of Journey Medical shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Journey Medical has higher revenue and earnings than Clene. Journey Medical is trading at a lower price-to-earnings ratio than Clene, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Clene$200K250.71-$26.17M-$3.50N/A
Journey Medical$61.86M2.88-$11.43M-$0.22N/A

In the previous week, Journey Medical had 2 more articles in the media than Clene. MarketBeat recorded 3 mentions for Journey Medical and 1 mentions for Clene. Journey Medical's average media sentiment score of 0.42 beat Clene's score of 0.00 indicating that Journey Medical is being referred to more favorably in the news media.

Company Overall Sentiment
Clene Neutral
Journey Medical Neutral

Clene has a beta of 0.91, indicating that its share price is 9% less volatile than the broader market. Comparatively, Journey Medical has a beta of 1.1, indicating that its share price is 10% more volatile than the broader market.

Journey Medical has a net margin of -8.95% compared to Clene's net margin of -20,063.96%. Clene's return on equity of 0.00% beat Journey Medical's return on equity.

Company Net Margins Return on Equity Return on Assets
Clene-20,063.96% N/A -137.04%
Journey Medical -8.95%-20.23%-6.60%

Clene presently has a consensus target price of $34.00, indicating a potential upside of 780.83%. Journey Medical has a consensus target price of $14.00, indicating a potential upside of 121.87%. Given Clene's stronger consensus rating and higher possible upside, analysts plainly believe Clene is more favorable than Journey Medical.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Clene
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71
Journey Medical
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

Summary

Clene and Journey Medical tied by winning 8 of the 16 factors compared between the two stocks.

How does Clene compare to Zentalis Pharmaceuticals?

Zentalis Pharmaceuticals (NASDAQ:ZNTL) and Clene (NASDAQ:CLNN) are both small-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their institutional ownership, profitability, analyst recommendations, dividends, earnings, risk, media sentiment and valuation.

Zentalis Pharmaceuticals currently has a consensus price target of $7.50, suggesting a potential upside of 184.09%. Clene has a consensus price target of $34.00, suggesting a potential upside of 780.83%. Given Clene's stronger consensus rating and higher possible upside, analysts clearly believe Clene is more favorable than Zentalis Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zentalis Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.50
Clene
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

Clene has lower revenue, but higher earnings than Zentalis Pharmaceuticals. Zentalis Pharmaceuticals is trading at a lower price-to-earnings ratio than Clene, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zentalis Pharmaceuticals$67.43M2.81-$137.06M-$1.95N/A
Clene$200K250.71-$26.17M-$3.50N/A

Zentalis Pharmaceuticals has a beta of 1.93, indicating that its stock price is 93% more volatile than the broader market. Comparatively, Clene has a beta of 0.91, indicating that its stock price is 9% less volatile than the broader market.

In the previous week, Zentalis Pharmaceuticals had 9 more articles in the media than Clene. MarketBeat recorded 10 mentions for Zentalis Pharmaceuticals and 1 mentions for Clene. Zentalis Pharmaceuticals' average media sentiment score of 0.33 beat Clene's score of 0.00 indicating that Zentalis Pharmaceuticals is being referred to more favorably in the media.

Company Overall Sentiment
Zentalis Pharmaceuticals Neutral
Clene Neutral

23.3% of Clene shares are held by institutional investors. 3.8% of Zentalis Pharmaceuticals shares are held by company insiders. Comparatively, 28.3% of Clene shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Zentalis Pharmaceuticals has a net margin of 0.00% compared to Clene's net margin of -20,063.96%. Clene's return on equity of 0.00% beat Zentalis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Zentalis PharmaceuticalsN/A -70.18% -51.46%
Clene -20,063.96%N/A -137.04%

Summary

Clene beats Zentalis Pharmaceuticals on 8 of the 15 factors compared between the two stocks.

How does Clene compare to Cardiol Therapeutics?

Cardiol Therapeutics (NASDAQ:CRDL) and Clene (NASDAQ:CLNN) are both small-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their risk, profitability, earnings, institutional ownership, analyst recommendations, valuation, dividends and media sentiment.

12.5% of Cardiol Therapeutics shares are owned by institutional investors. Comparatively, 23.3% of Clene shares are owned by institutional investors. 5.3% of Cardiol Therapeutics shares are owned by company insiders. Comparatively, 28.3% of Clene shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

In the previous week, Cardiol Therapeutics and Cardiol Therapeutics both had 1 articles in the media. Cardiol Therapeutics' average media sentiment score of 0.00 equaled Clene'saverage media sentiment score.

Company Overall Sentiment
Cardiol Therapeutics Neutral
Clene Neutral

Cardiol Therapeutics has a beta of 0.88, suggesting that its stock price is 12% less volatile than the broader market. Comparatively, Clene has a beta of 0.91, suggesting that its stock price is 9% less volatile than the broader market.

Cardiol Therapeutics has a net margin of 0.00% compared to Clene's net margin of -20,063.96%. Clene's return on equity of 0.00% beat Cardiol Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Cardiol TherapeuticsN/A -180.44% -140.28%
Clene -20,063.96%N/A -137.04%

Cardiol Therapeutics has higher earnings, but lower revenue than Clene. Cardiol Therapeutics is trading at a lower price-to-earnings ratio than Clene, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cardiol TherapeuticsN/AN/A-$24.20M-$0.25N/A
Clene$200K250.71-$26.17M-$3.50N/A

Cardiol Therapeutics presently has a consensus price target of $10.00, indicating a potential upside of 713.01%. Clene has a consensus price target of $34.00, indicating a potential upside of 780.83%. Given Clene's stronger consensus rating and higher probable upside, analysts plainly believe Clene is more favorable than Cardiol Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cardiol Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Clene
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

Summary

Clene beats Cardiol Therapeutics on 10 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding CLNN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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CLNN vs. The Competition

MetricClenePharmaceuticals IndustryHealthcare SectorNASDAQ Exchange
Market Cap$50.42M$12.32B$7.16B$13.21B
Dividend YieldN/A2.64%2.53%16.37%
P/E Ratio-1.10797.58274.1526.16
Price / Sales250.71939.82635.98113.06
Price / CashN/A85.9776.3853.09
Price / Book-2.3810.7111.216.34
Net Income-$26.17M$2.84B$3.50B$381.90M
7 Day Performance-5.39%-0.93%-0.90%-1.41%
1 Month Performance5.75%-4.91%-4.44%-3.48%
1 Year Performance-55.12%-4.13%6.96%1.16%

Clene Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
CLNN
Clene
1.9215 of 5 stars
$3.86
-0.5%
$34.00
+780.8%
-59.1%$50.42M$200KN/A79
SLGL
Sol-Gel Technologies
3.5434 of 5 stars
$78.95
+9.7%
$197.50
+150.2%
+81.0%$202.31M$1.80MN/A28
ACOG
Alpha Cognition
3.8895 of 5 stars
$9.15
+0.5%
$18.00
+96.7%
+19.4%$198.18M$10.22MN/A71
DERM
Journey Medical
1.7248 of 5 stars
$6.69
+1.2%
$14.00
+109.3%
-16.4%$186.56M$68.18MN/A58
ZNTL
Zentalis Pharmaceuticals
3.3745 of 5 stars
$2.78
+10.3%
$7.50
+169.8%
+45.9%$180.61M$67.43MN/A106

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This page (NASDAQ:CLNN) was last updated on 10/10/2026 by MarketBeat.com Staff.
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