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SOPHiA GENETICS (SOPH) Competitors

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$5.67 0.00 (0.00%)
Closing price 07/31/2026 04:00 PM Eastern
Extended Trading
$5.66 -0.01 (-0.18%)
As of 07/31/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

SOPH vs. OCUL, MESO, LKFT, TYRA, and BCAX

Should you buy SOPHiA GENETICS stock or one of its competitors? MarketBeat compares SOPHiA GENETICS with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with SOPHiA GENETICS include Ocular Therapeutix (OCUL), Mesoblast (MESO), Lakefront Biotherapeutics American Depositary Shares (LKFT), Tyra Biosciences (TYRA), and Bicara Therapeutics (BCAX).

How does SOPHiA GENETICS compare to Ocular Therapeutix?

SOPHiA GENETICS (NASDAQ:SOPH) and Ocular Therapeutix (NASDAQ:OCUL) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, media sentiment, institutional ownership, risk, dividends, analyst recommendations, earnings and valuation.

SOPHiA GENETICS has a beta of 0.96, indicating that its share price is 4% less volatile than the broader market. Comparatively, Ocular Therapeutix has a beta of 0.93, indicating that its share price is 7% less volatile than the broader market.

In the previous week, Ocular Therapeutix had 3 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 12 mentions for Ocular Therapeutix and 9 mentions for SOPHiA GENETICS. Ocular Therapeutix's average media sentiment score of 0.65 beat SOPHiA GENETICS's score of 0.27 indicating that Ocular Therapeutix is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SOPHiA GENETICS
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ocular Therapeutix
4 Very Positive mention(s)
0 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

SOPHiA GENETICS has higher revenue and earnings than Ocular Therapeutix. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than Ocular Therapeutix, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SOPHiA GENETICS$77.27M6.16-$79M-$0.52N/A
Ocular Therapeutix$51.95M34.44-$265.94M-$1.46N/A

SOPHiA GENETICS presently has a consensus price target of $9.00, indicating a potential upside of 58.73%. Ocular Therapeutix has a consensus price target of $25.11, indicating a potential upside of 207.36%. Given Ocular Therapeutix's stronger consensus rating and higher probable upside, analysts clearly believe Ocular Therapeutix is more favorable than SOPHiA GENETICS.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SOPHiA GENETICS
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Ocular Therapeutix
2 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
0 Strong Buy rating(s)
2.71

SOPHiA GENETICS has a net margin of -44.48% compared to Ocular Therapeutix's net margin of -558.24%. SOPHiA GENETICS's return on equity of -62.74% beat Ocular Therapeutix's return on equity.

Company Net Margins Return on Equity Return on Assets
SOPHiA GENETICS-44.48% -62.74% -21.85%
Ocular Therapeutix -558.24%-64.28%-48.15%

31.6% of SOPHiA GENETICS shares are held by institutional investors. Comparatively, 59.2% of Ocular Therapeutix shares are held by institutional investors. 4.9% of SOPHiA GENETICS shares are held by company insiders. Comparatively, 3.1% of Ocular Therapeutix shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Summary

SOPHiA GENETICS and Ocular Therapeutix tied by winning 8 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Mesoblast?

Mesoblast (NASDAQ:MESO) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their media sentiment, analyst recommendations, institutional ownership, profitability, valuation, risk, dividends and earnings.

SOPHiA GENETICS has a consensus target price of $9.00, indicating a potential upside of 58.73%. Given SOPHiA GENETICS's higher probable upside, analysts clearly believe SOPHiA GENETICS is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.50
SOPHiA GENETICS
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

In the previous week, SOPHiA GENETICS had 6 more articles in the media than Mesoblast. MarketBeat recorded 9 mentions for SOPHiA GENETICS and 3 mentions for Mesoblast. SOPHiA GENETICS's average media sentiment score of 0.27 beat Mesoblast's score of 0.00 indicating that SOPHiA GENETICS is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
SOPHiA GENETICS
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Mesoblast has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -44.48%. Mesoblast's return on equity of 0.00% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
SOPHiA GENETICS -44.48%-62.74%-21.85%

SOPHiA GENETICS has higher revenue and earnings than Mesoblast. Mesoblast is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M107.00-$102.14M-$0.28N/A
SOPHiA GENETICS$77.27M6.16-$79M-$0.52N/A

Mesoblast has a beta of 2.08, meaning that its share price is 108% more volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.96, meaning that its share price is 4% less volatile than the broader market.

1.4% of Mesoblast shares are owned by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are owned by institutional investors. 18.8% of Mesoblast shares are owned by insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Summary

Mesoblast beats SOPHiA GENETICS on 9 of the 17 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Lakefront Biotherapeutics American Depositary Shares?

Lakefront Biotherapeutics American Depositary Shares (NASDAQ:LKFT) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, risk, earnings, profitability, dividends, valuation and analyst recommendations.

Lakefront Biotherapeutics American Depositary Shares has a beta of 0.25, indicating that its stock price is 75% less volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.96, indicating that its stock price is 4% less volatile than the broader market.

Lakefront Biotherapeutics American Depositary Shares presently has a consensus target price of $34.33, indicating a potential upside of 26.18%. SOPHiA GENETICS has a consensus target price of $9.00, indicating a potential upside of 58.73%. Given SOPHiA GENETICS's stronger consensus rating and higher probable upside, analysts plainly believe SOPHiA GENETICS is more favorable than Lakefront Biotherapeutics American Depositary Shares.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lakefront Biotherapeutics American Depositary Shares
1 Sell rating(s)
7 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.11
SOPHiA GENETICS
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Lakefront Biotherapeutics American Depositary Shares has higher revenue and earnings than SOPHiA GENETICS. Lakefront Biotherapeutics American Depositary Shares is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lakefront Biotherapeutics American Depositary Shares$1.04B1.72$363.05M-$1.41N/A
SOPHiA GENETICS$77.27M6.16-$79M-$0.52N/A

In the previous week, SOPHiA GENETICS had 8 more articles in the media than Lakefront Biotherapeutics American Depositary Shares. MarketBeat recorded 9 mentions for SOPHiA GENETICS and 1 mentions for Lakefront Biotherapeutics American Depositary Shares. SOPHiA GENETICS's average media sentiment score of 0.27 beat Lakefront Biotherapeutics American Depositary Shares' score of 0.00 indicating that SOPHiA GENETICS is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lakefront Biotherapeutics American Depositary Shares
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
SOPHiA GENETICS
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lakefront Biotherapeutics American Depositary Shares has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -44.48%. Lakefront Biotherapeutics American Depositary Shares' return on equity of 0.00% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
Lakefront Biotherapeutics American Depositary SharesN/A N/A N/A
SOPHiA GENETICS -44.48%-62.74%-21.85%

32.5% of Lakefront Biotherapeutics American Depositary Shares shares are owned by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are owned by institutional investors. 2.9% of Lakefront Biotherapeutics American Depositary Shares shares are owned by company insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Summary

SOPHiA GENETICS beats Lakefront Biotherapeutics American Depositary Shares on 10 of the 17 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Tyra Biosciences?

Tyra Biosciences (NASDAQ:TYRA) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, analyst recommendations, earnings, valuation, institutional ownership, dividends, media sentiment and profitability.

In the previous week, SOPHiA GENETICS had 5 more articles in the media than Tyra Biosciences. MarketBeat recorded 9 mentions for SOPHiA GENETICS and 4 mentions for Tyra Biosciences. Tyra Biosciences' average media sentiment score of 1.66 beat SOPHiA GENETICS's score of 0.27 indicating that Tyra Biosciences is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Tyra Biosciences
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
SOPHiA GENETICS
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Tyra Biosciences presently has a consensus price target of $47.00, indicating a potential upside of 47.43%. SOPHiA GENETICS has a consensus price target of $9.00, indicating a potential upside of 58.73%. Given SOPHiA GENETICS's higher possible upside, analysts clearly believe SOPHiA GENETICS is more favorable than Tyra Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tyra Biosciences
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87
SOPHiA GENETICS
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

84.1% of Tyra Biosciences shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 12.5% of Tyra Biosciences shares are held by insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Tyra Biosciences has a beta of 0.77, indicating that its share price is 23% less volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.96, indicating that its share price is 4% less volatile than the broader market.

Tyra Biosciences has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -44.48%. Tyra Biosciences' return on equity of -42.66% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
Tyra BiosciencesN/A -42.66% -39.79%
SOPHiA GENETICS -44.48%-62.74%-21.85%

SOPHiA GENETICS has higher revenue and earnings than Tyra Biosciences. Tyra Biosciences is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tyra BiosciencesN/AN/A-$119.95M-$2.18N/A
SOPHiA GENETICS$77.27M6.16-$79M-$0.52N/A

Summary

Tyra Biosciences and SOPHiA GENETICS tied by winning 8 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Bicara Therapeutics?

SOPHiA GENETICS (NASDAQ:SOPH) and Bicara Therapeutics (NASDAQ:BCAX) are both small-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, dividends, valuation, risk, earnings, profitability, media sentiment and institutional ownership.

31.6% of SOPHiA GENETICS shares are owned by institutional investors. 4.9% of SOPHiA GENETICS shares are owned by company insiders. Comparatively, 13.8% of Bicara Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

In the previous week, SOPHiA GENETICS had 5 more articles in the media than Bicara Therapeutics. MarketBeat recorded 9 mentions for SOPHiA GENETICS and 4 mentions for Bicara Therapeutics. Bicara Therapeutics' average media sentiment score of 1.22 beat SOPHiA GENETICS's score of 0.27 indicating that Bicara Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SOPHiA GENETICS
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Bicara Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

SOPHiA GENETICS presently has a consensus target price of $9.00, suggesting a potential upside of 58.73%. Bicara Therapeutics has a consensus target price of $30.27, suggesting a potential upside of 11.71%. Given SOPHiA GENETICS's higher possible upside, equities analysts clearly believe SOPHiA GENETICS is more favorable than Bicara Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SOPHiA GENETICS
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Bicara Therapeutics
1 Sell rating(s)
3 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.73

SOPHiA GENETICS has a beta of 0.96, meaning that its share price is 4% less volatile than the broader market. Comparatively, Bicara Therapeutics has a beta of -0.81, meaning that its share price is 181% less volatile than the broader market.

SOPHiA GENETICS has higher revenue and earnings than Bicara Therapeutics. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than Bicara Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SOPHiA GENETICS$77.27M6.16-$79M-$0.52N/A
Bicara TherapeuticsN/AN/A-$137.95M-$2.78N/A

Bicara Therapeutics has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -44.48%. Bicara Therapeutics' return on equity of -35.89% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
SOPHiA GENETICS-44.48% -62.74% -21.85%
Bicara Therapeutics N/A -35.89%-33.78%

Summary

SOPHiA GENETICS and Bicara Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SOPH and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SOPH vs. The Competition

MetricSOPHiA GENETICSHealthcare Technology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$475.66M$1.35B$6.85B$12.42B
Dividend YieldN/A4.76%2.59%10.03%
P/E Ratio-10.90275.31282.3024.66
Price / Sales6.1659.32563.1275.93
Price / CashN/A30.5628.6046.71
Price / Book8.224.6110.966.07
Net Income-$79M-$25.90M$3.49B$347.99M
7 Day Performance0.35%-0.49%-0.64%-0.44%
1 Month Performance5.98%-4.66%-5.23%-4.81%
1 Year Performance79.43%-19.83%61.97%18.61%

SOPHiA GENETICS Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SOPH
SOPHiA GENETICS
3.2071 of 5 stars
$5.67
flat
$9.00
+58.7%
+79.4%$475.66M$77.27MN/A520
OCUL
Ocular Therapeutix
2.7548 of 5 stars
$8.45
-2.2%
$25.11
+197.2%
-31.5%$1.89B$51.95MN/A230
MESO
Mesoblast
0.3351 of 5 stars
$14.45
-0.8%
N/A-6.6%$1.89B$17.20MN/A80
LKFT
Lakefront Biotherapeutics American Depositary Shares
1.7087 of 5 stars
$28.15
+0.1%
$34.33
+22.0%
-16.8%$1.85B$1.26BN/A1,310
TYRA
Tyra Biosciences
3.1442 of 5 stars
$30.88
-0.6%
$47.00
+52.2%
+207.4%$1.85BN/AN/A20

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This page (NASDAQ:SOPH) was last updated on 8/3/2026 by MarketBeat.com Staff.
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