Is SOPH or CERT more profitable?

Certara has a net margin of -16.75% compared to SOPHiA GENETICS's net margin of -93.86%. Certara's return on equity of 3.86% beat SOPHiA GENETICS's return on equity. Company Net Margins Return on Equity Return on Assets SOPHiA GENETICS -93.86% -132.47% -45.97% Certara -16.75% 3.86% 2.65%

Which has preferable earnings and valuation, GDRX or SOPH?

GoodRx has higher revenue and earnings than SOPHiA GENETICS. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than GoodRx, indicating that it is currently the more affordable of the two stocks. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio GoodRx $796.85M 1.40 $30.44M $0.04 81.13 SOPHiA GENETICS $77.27M 8.72 -$79M -$1.15 N/A

Is GDRX or SOPH more profitable?

GoodRx has a net margin of 2.07% compared to SOPHiA GENETICS's net margin of -93.86%. GoodRx's return on equity of 7.22% beat SOPHiA GENETICS's return on equity. Company Net Margins Return on Equity Return on Assets GoodRx 2.07% 7.22% 2.53% SOPHiA GENETICS -93.86% -132.47% -45.97%

SOPHiA GENETICS (SOPH) Competitors

$8.07 +0.04 (+0.50%)

Closing price 04:00 PM Eastern

Extended Trading

$8.24 +0.17 (+2.11%)

As of 07:30 PM Eastern

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SOPH vs. SDGR, CERT, GDRX, TDOC, and HSTM

Should you buy SOPHiA GENETICS stock or one of its competitors? SOPHiA GENETICS's main competitors and comparable companies include Schrodinger (SDGR), Certara (CERT), GoodRx (GDRX), Teladoc Health (TDOC), and HealthStream (HSTM). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "healthcare technology" industry.

How does SOPHiA GENETICS compare to Schrodinger?

Schrodinger (NASDAQ:SDGR) and SOPHiA GENETICS (NASDAQ:SOPH) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their media sentiment, profitability, valuation, risk, analyst recommendations, earnings, dividends and institutional ownership.

Schrodinger has a beta of 1.61, indicating that its stock price is 61% more volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.95, indicating that its stock price is 5% less volatile than the broader market.

SOPHiA GENETICS has lower revenue, but higher earnings than Schrodinger. Schrodinger is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Schrodinger	$255.87M	8.81	-$103.26M	-$0.74	N/A
SOPHiA GENETICS	$77.27M	8.72	-$79M	-$1.15	N/A

In the previous week, Schrodinger had 4 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 4 mentions for Schrodinger and 0 mentions for SOPHiA GENETICS. Schrodinger's average media sentiment score of 1.05 beat SOPHiA GENETICS's score of 0.00 indicating that Schrodinger is being referred to more favorably in the media.

Company	Overall Sentiment
Schrodinger	Positive
SOPHiA GENETICS	Neutral

Schrodinger has a net margin of -20.98% compared to SOPHiA GENETICS's net margin of -93.86%. Schrodinger's return on equity of -16.37% beat SOPHiA GENETICS's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Schrodinger	-20.98%	-16.37%	-8.19%
SOPHiA GENETICS	-93.86%	-132.47%	-45.97%

79.1% of Schrodinger shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 10.1% of Schrodinger shares are held by company insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Schrodinger currently has a consensus target price of $20.80, suggesting a potential downside of 31.91%. SOPHiA GENETICS has a consensus target price of $10.00, suggesting a potential upside of 24.46%. Given SOPHiA GENETICS's stronger consensus rating and higher possible upside, analysts clearly believe SOPHiA GENETICS is more favorable than Schrodinger.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Schrodinger	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.33
SOPHiA GENETICS	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40

Summary

Schrodinger beats SOPHiA GENETICS on 11 of the 15 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Certara?

SOPHiA GENETICS (NASDAQ:SOPH) and Certara (NASDAQ:CERT) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, profitability, media sentiment, risk, valuation, institutional ownership, analyst recommendations and earnings.

SOPHiA GENETICS has a beta of 0.95, indicating that its share price is 5% less volatile than the broader market. Comparatively, Certara has a beta of 1.42, indicating that its share price is 42% more volatile than the broader market.

Certara has a net margin of -16.75% compared to SOPHiA GENETICS's net margin of -93.86%. Certara's return on equity of 3.86% beat SOPHiA GENETICS's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
SOPHiA GENETICS	-93.86%	-132.47%	-45.97%
Certara	-16.75%	3.86%	2.65%

31.6% of SOPHiA GENETICS shares are held by institutional investors. Comparatively, 74.0% of Certara shares are held by institutional investors. 4.9% of SOPHiA GENETICS shares are held by insiders. Comparatively, 1.1% of Certara shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Certara has higher revenue and earnings than SOPHiA GENETICS. Certara is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
SOPHiA GENETICS	$77.27M	8.72	-$79M	-$1.15	N/A
Certara	$418.84M	3.35	-$1.60M	-$0.45	N/A

SOPHiA GENETICS presently has a consensus price target of $10.00, indicating a potential upside of 24.46%. Certara has a consensus price target of $8.45, indicating a potential downside of 8.20%. Given SOPHiA GENETICS's higher probable upside, analysts plainly believe SOPHiA GENETICS is more favorable than Certara.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
SOPHiA GENETICS	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40
Certara	1 Sell rating(s)	6 Hold rating(s)	4 Buy rating(s)	1 Strong Buy rating(s)	2.42

In the previous week, Certara had 6 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 6 mentions for Certara and 0 mentions for SOPHiA GENETICS. Certara's average media sentiment score of 0.69 beat SOPHiA GENETICS's score of 0.00 indicating that Certara is being referred to more favorably in the news media.

Company	Overall Sentiment
SOPHiA GENETICS	Neutral
Certara	Positive

Summary

Certara beats SOPHiA GENETICS on 13 of the 17 factors compared between the two stocks.

How does SOPHiA GENETICS compare to GoodRx?

GoodRx (NASDAQ:GDRX) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, institutional ownership, risk, dividends, media sentiment, valuation and earnings.

GoodRx has higher revenue and earnings than SOPHiA GENETICS. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than GoodRx, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
GoodRx	$796.85M	1.40	$30.44M	$0.04	81.13
SOPHiA GENETICS	$77.27M	8.72	-$79M	-$1.15	N/A

In the previous week, GoodRx had 1 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 1 mentions for GoodRx and 0 mentions for SOPHiA GENETICS. GoodRx's average media sentiment score of 0.50 beat SOPHiA GENETICS's score of 0.00 indicating that GoodRx is being referred to more favorably in the media.

Company	Overall Sentiment
GoodRx	Positive
SOPHiA GENETICS	Neutral

GoodRx has a beta of 1.69, meaning that its stock price is 69% more volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.95, meaning that its stock price is 5% less volatile than the broader market.

GoodRx currently has a consensus price target of $4.23, suggesting a potential upside of 30.27%. SOPHiA GENETICS has a consensus price target of $10.00, suggesting a potential upside of 24.46%. Given GoodRx's higher possible upside, equities analysts plainly believe GoodRx is more favorable than SOPHiA GENETICS.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
GoodRx	3 Sell rating(s)	6 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.08
SOPHiA GENETICS	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40

63.8% of GoodRx shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 5.9% of GoodRx shares are held by company insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

GoodRx has a net margin of 2.07% compared to SOPHiA GENETICS's net margin of -93.86%. GoodRx's return on equity of 7.22% beat SOPHiA GENETICS's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
GoodRx	2.07%	7.22%	2.53%
SOPHiA GENETICS	-93.86%	-132.47%	-45.97%

Summary

GoodRx beats SOPHiA GENETICS on 14 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Teladoc Health?

Teladoc Health (NYSE:TDOC) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, valuation, risk, institutional ownership, media sentiment, earnings, analyst recommendations and dividends.

Teladoc Health has a net margin of -7.13% compared to SOPHiA GENETICS's net margin of -93.86%. Teladoc Health's return on equity of -12.15% beat SOPHiA GENETICS's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Teladoc Health	-7.13%	-12.15%	-5.83%
SOPHiA GENETICS	-93.86%	-132.47%	-45.97%

76.8% of Teladoc Health shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 0.7% of Teladoc Health shares are held by company insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Teladoc Health presently has a consensus target price of $7.54, suggesting a potential upside of 36.39%. SOPHiA GENETICS has a consensus target price of $10.00, suggesting a potential upside of 24.46%. Given Teladoc Health's higher possible upside, analysts clearly believe Teladoc Health is more favorable than SOPHiA GENETICS.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Teladoc Health	1 Sell rating(s)	10 Hold rating(s)	5 Buy rating(s)	0 Strong Buy rating(s)	2.25
SOPHiA GENETICS	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40

In the previous week, Teladoc Health had 8 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 8 mentions for Teladoc Health and 0 mentions for SOPHiA GENETICS. Teladoc Health's average media sentiment score of 0.66 beat SOPHiA GENETICS's score of 0.00 indicating that Teladoc Health is being referred to more favorably in the media.

Company	Overall Sentiment
Teladoc Health	Positive
SOPHiA GENETICS	Neutral

SOPHiA GENETICS has lower revenue, but higher earnings than Teladoc Health. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than Teladoc Health, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Teladoc Health	$2.53B	0.40	-$200.32M	-$0.99	N/A
SOPHiA GENETICS	$77.27M	8.72	-$79M	-$1.15	N/A

Teladoc Health has a beta of 2.14, suggesting that its stock price is 114% more volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.95, suggesting that its stock price is 5% less volatile than the broader market.

Summary

Teladoc Health beats SOPHiA GENETICS on 12 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to HealthStream?

HealthStream (NASDAQ:HSTM) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, media sentiment, risk, valuation, institutional ownership, earnings, analyst recommendations and profitability.

HealthStream has higher revenue and earnings than SOPHiA GENETICS. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than HealthStream, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
HealthStream	$304.06M	2.95	$18.34M	$0.72	42.63
SOPHiA GENETICS	$77.27M	8.72	-$79M	-$1.15	N/A

In the previous week, HealthStream had 3 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 3 mentions for HealthStream and 0 mentions for SOPHiA GENETICS. HealthStream's average media sentiment score of 1.27 beat SOPHiA GENETICS's score of 0.00 indicating that HealthStream is being referred to more favorably in the media.

Company	Overall Sentiment
HealthStream	Positive
SOPHiA GENETICS	Neutral

HealthStream has a beta of 0.42, suggesting that its stock price is 58% less volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.95, suggesting that its stock price is 5% less volatile than the broader market.

HealthStream presently has a consensus price target of $27.00, suggesting a potential downside of 12.02%. SOPHiA GENETICS has a consensus price target of $10.00, suggesting a potential upside of 24.46%. Given SOPHiA GENETICS's stronger consensus rating and higher possible upside, analysts clearly believe SOPHiA GENETICS is more favorable than HealthStream.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
HealthStream	0 Sell rating(s)	3 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	2.00
SOPHiA GENETICS	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40

69.6% of HealthStream shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 20.4% of HealthStream shares are held by insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

HealthStream has a net margin of 6.60% compared to SOPHiA GENETICS's net margin of -93.86%. HealthStream's return on equity of 6.81% beat SOPHiA GENETICS's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
HealthStream	6.60%	6.81%	4.64%
SOPHiA GENETICS	-93.86%	-132.47%	-45.97%

Summary

HealthStream beats SOPHiA GENETICS on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SOPH and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

SOPH vs. The Competition

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Metric	SOPHiA GENETICS	Healthcare Technology Industry	Healthcare Sector	NASDAQ Exchange
Market Cap	$676.99M	$1.70B	$7.09B	$13.24B
Dividend Yield	N/A	3.95%	2.53%	15.88%
P/E Ratio	-7.02	21.02	274.61	26.05
Price / Sales	8.76	85.95	600.52	89.39
Price / Cash	N/A	31.91	77.38	51.25
Price / Book	11.70	6.16	10.92	6.31
Net Income	-$79M	-$26.60M	$3.50B	$361.43M
7 Day Performance	-3.24%	-1.55%	-2.11%	-1.67%
1 Month Performance	-2.54%	-1.04%	-6.34%	-3.94%
1 Year Performance	80.54%	-20.89%	8.81%	2.77%

SOPHiA GENETICS Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
SOPH SOPHiA GENETICS	2.8594 of 5 stars	$8.07 +0.5%	$10.00 +23.9%	+80.4%	$676.99M	$77.27M	N/A	415	High Trading Volume
SDGR Schrodinger	1.3879 of 5 stars	$30.70 +1.5%	$20.50 -33.2%	+43.6%	$2.23B	$255.87M	N/A	850	Positive News
CERT Certara	1.7935 of 5 stars	$8.83 +3.6%	$8.28 -6.3%	-30.1%	$1.30B	$418.84M	N/A	1,576	Analyst Upgrade
GDRX GoodRx	3.8451 of 5 stars	$3.44 +1.5%	$4.23 +22.9%	-35.0%	$1.16B	$796.85M	86.02	697
TDOC Teladoc Health	3.2928 of 5 stars	$6.34 +1.1%	$7.54 +18.8%	-27.1%	$1.14B	$2.53B	N/A	5,600

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This page (NASDAQ:SOPH) was last updated on 10/2/2026 by MarketBeat.com Staff.

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SOPHiA GENETICS (SOPH) Competitors

SOPH vs. SDGR, CERT, GDRX, TDOC, and HSTM

How does SOPHiA GENETICS compare to Schrodinger?

Summary

How does SOPHiA GENETICS compare to Certara?

Summary

How does SOPHiA GENETICS compare to GoodRx?

Summary

How does SOPHiA GENETICS compare to Teladoc Health?

Summary

How does SOPHiA GENETICS compare to HealthStream?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

SOPH vs. The Competition

SOPHiA GENETICS Competitors List

Related Companies and Tools

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools

About MarketBeat

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SOPHiA GENETICS (SOPH) Competitors

SOPH vs. SDGR, CERT, GDRX, TDOC, and HSTM

How does SOPHiA GENETICS compare to Schrodinger?

Which has more risk & volatility, SDGR or SOPH?

Which has preferable earnings & valuation, SDGR or SOPH?

Does the media favor SDGR or SOPH?

Is SDGR or SOPH more profitable?

Do institutionals and insiders hold more shares of SDGR or SOPH?

Do analysts recommend SDGR or SOPH?

Summary

How does SOPHiA GENETICS compare to Certara?

Which has more volatility & risk, SOPH or CERT?

Is SOPH or CERT more profitable?

Do institutionals & insiders believe in SOPH or CERT?

Which has stronger earnings & valuation, SOPH or CERT?

Do analysts prefer SOPH or CERT?

Does the media favor SOPH or CERT?

Summary

How does SOPHiA GENETICS compare to GoodRx?

Which has preferable earnings and valuation, GDRX or SOPH?

Does the media prefer GDRX or SOPH?

Which has more volatility and risk, GDRX or SOPH?

Do analysts rate GDRX or SOPH?

Do institutionals and insiders have more ownership in GDRX or SOPH?

Is GDRX or SOPH more profitable?

Summary

How does SOPHiA GENETICS compare to Teladoc Health?

Is TDOC or SOPH more profitable?

Do institutionals and insiders have more ownership in TDOC or SOPH?

Do analysts rate TDOC or SOPH?

Does the media refer more to TDOC or SOPH?

Which has better valuation and earnings, TDOC or SOPH?

Which has more risk and volatility, TDOC or SOPH?

Summary

How does SOPHiA GENETICS compare to HealthStream?

Which has preferable valuation & earnings, HSTM or SOPH?

Does the media favor HSTM or SOPH?

Which has more volatility & risk, HSTM or SOPH?

Do analysts prefer HSTM or SOPH?

Do institutionals and insiders hold more shares of HSTM or SOPH?

Is HSTM or SOPH more profitable?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

SOPH vs. The Competition

SOPHiA GENETICS Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools