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SOPHiA GENETICS (SOPH) Competitors

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$4.78 -0.16 (-3.24%)
Closing price 04:00 PM Eastern
Extended Trading
$4.78 +0.00 (+0.10%)
As of 05:46 PM Eastern
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SOPH vs. SEPN, AVBP, COAG, HROW, and WVE

Should you buy SOPHiA GENETICS stock or one of its competitors? MarketBeat compares SOPHiA GENETICS with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with SOPHiA GENETICS include Septerna (SEPN), ArriVent BioPharma (AVBP), Hemab Therapeutics (COAG), Harrow (HROW), and WAVE Life Sciences (WVE). These companies are all part of the "pharmaceutical products" industry.

How does SOPHiA GENETICS compare to Septerna?

SOPHiA GENETICS (NASDAQ:SOPH) and Septerna (NASDAQ:SEPN) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their dividends, institutional ownership, risk, analyst recommendations, profitability, earnings, valuation and media sentiment.

SOPHiA GENETICS has a beta of 0.98, indicating that its stock price is 2% less volatile than the broader market. Comparatively, Septerna has a beta of 2.39, indicating that its stock price is 139% more volatile than the broader market.

SOPHiA GENETICS has a net margin of -44.48% compared to Septerna's net margin of -49.88%. Septerna's return on equity of -12.72% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
SOPHiA GENETICS-44.48% -62.74% -21.85%
Septerna -49.88%-12.72%-8.87%

SOPHiA GENETICS currently has a consensus target price of $7.50, indicating a potential upside of 56.90%. Septerna has a consensus target price of $43.13, indicating a potential upside of 41.16%. Given SOPHiA GENETICS's higher probable upside, analysts clearly believe SOPHiA GENETICS is more favorable than Septerna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SOPHiA GENETICS
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Septerna
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80

In the previous week, SOPHiA GENETICS and SOPHiA GENETICS both had 3 articles in the media. SOPHiA GENETICS's average media sentiment score of 0.91 beat Septerna's score of 0.55 indicating that SOPHiA GENETICS is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SOPHiA GENETICS
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Septerna
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Septerna has lower revenue, but higher earnings than SOPHiA GENETICS. Septerna is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SOPHiA GENETICS$81.18M4.03-$79M-$0.52N/A
Septerna$45.95M29.97-$48.88M-$0.81N/A

31.6% of SOPHiA GENETICS shares are owned by institutional investors. 4.9% of SOPHiA GENETICS shares are owned by insiders. Comparatively, 4.3% of Septerna shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

SOPHiA GENETICS and Septerna tied by winning 8 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to ArriVent BioPharma?

ArriVent BioPharma (NASDAQ:AVBP) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, earnings, institutional ownership, media sentiment, valuation, risk, analyst recommendations and dividends.

ArriVent BioPharma has a beta of 1.41, indicating that its share price is 41% more volatile than the broader market. Comparatively, SOPHiA GENETICS has a beta of 0.98, indicating that its share price is 2% less volatile than the broader market.

9.5% of ArriVent BioPharma shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 8.6% of ArriVent BioPharma shares are held by company insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

ArriVent BioPharma presently has a consensus target price of $43.38, suggesting a potential upside of 45.65%. SOPHiA GENETICS has a consensus target price of $7.50, suggesting a potential upside of 56.90%. Given SOPHiA GENETICS's higher probable upside, analysts clearly believe SOPHiA GENETICS is more favorable than ArriVent BioPharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
ArriVent BioPharma
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82
SOPHiA GENETICS
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

ArriVent BioPharma has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -44.48%. ArriVent BioPharma's return on equity of -48.98% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
ArriVent BioPharmaN/A -48.98% -45.44%
SOPHiA GENETICS -44.48%-62.74%-21.85%

SOPHiA GENETICS has higher revenue and earnings than ArriVent BioPharma. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than ArriVent BioPharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ArriVent BioPharmaN/AN/A-$166.31M-$3.47N/A
SOPHiA GENETICS$81.18M4.03-$79M-$0.52N/A

In the previous week, SOPHiA GENETICS had 2 more articles in the media than ArriVent BioPharma. MarketBeat recorded 3 mentions for SOPHiA GENETICS and 1 mentions for ArriVent BioPharma. ArriVent BioPharma's average media sentiment score of 1.87 beat SOPHiA GENETICS's score of 0.91 indicating that ArriVent BioPharma is being referred to more favorably in the media.

Company Overall Sentiment
ArriVent BioPharma Very Positive
SOPHiA GENETICS Positive

Summary

ArriVent BioPharma beats SOPHiA GENETICS on 9 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Hemab Therapeutics?

Hemab Therapeutics (NASDAQ:COAG) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap pharmaceutical products companies, but which is the superior stock? We will compare the two businesses based on the strength of their profitability, institutional ownership, earnings, risk, dividends, valuation, analyst recommendations and media sentiment.

Hemab Therapeutics currently has a consensus price target of $41.75, suggesting a potential upside of 59.53%. SOPHiA GENETICS has a consensus price target of $7.50, suggesting a potential upside of 56.90%. Given Hemab Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Hemab Therapeutics is more favorable than SOPHiA GENETICS.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Hemab Therapeutics
0 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.80
SOPHiA GENETICS
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

Hemab Therapeutics has higher earnings, but lower revenue than SOPHiA GENETICS.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Hemab TherapeuticsN/AN/AN/AN/AN/A
SOPHiA GENETICS$81.18M4.03-$79M-$0.52N/A

Hemab Therapeutics has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -44.48%. Hemab Therapeutics' return on equity of 0.00% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
Hemab TherapeuticsN/A N/A N/A
SOPHiA GENETICS -44.48%-62.74%-21.85%

31.6% of SOPHiA GENETICS shares are held by institutional investors. 4.9% of SOPHiA GENETICS shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

In the previous week, Hemab Therapeutics had 2 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 5 mentions for Hemab Therapeutics and 3 mentions for SOPHiA GENETICS. SOPHiA GENETICS's average media sentiment score of 0.91 beat Hemab Therapeutics' score of 0.61 indicating that SOPHiA GENETICS is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Hemab Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
SOPHiA GENETICS
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Hemab Therapeutics beats SOPHiA GENETICS on 7 of the 11 factors compared between the two stocks.

How does SOPHiA GENETICS compare to Harrow?

SOPHiA GENETICS (NASDAQ:SOPH) and Harrow (NASDAQ:HROW) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their dividends, earnings, analyst recommendations, institutional ownership, valuation, media sentiment, risk and profitability.

SOPHiA GENETICS has a beta of 0.98, suggesting that its share price is 2% less volatile than the broader market. Comparatively, Harrow has a beta of 0.28, suggesting that its share price is 72% less volatile than the broader market.

31.6% of SOPHiA GENETICS shares are owned by institutional investors. Comparatively, 72.8% of Harrow shares are owned by institutional investors. 4.9% of SOPHiA GENETICS shares are owned by company insiders. Comparatively, 12.8% of Harrow shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Harrow has a net margin of -5.57% compared to SOPHiA GENETICS's net margin of -44.48%. Harrow's return on equity of 19.59% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
SOPHiA GENETICS-44.48% -62.74% -21.85%
Harrow -5.57%19.59%2.26%

SOPHiA GENETICS currently has a consensus price target of $7.50, indicating a potential upside of 56.90%. Harrow has a consensus price target of $69.43, indicating a potential upside of 108.37%. Given Harrow's stronger consensus rating and higher possible upside, analysts plainly believe Harrow is more favorable than SOPHiA GENETICS.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SOPHiA GENETICS
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Harrow
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.64

In the previous week, Harrow had 1 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 4 mentions for Harrow and 3 mentions for SOPHiA GENETICS. SOPHiA GENETICS's average media sentiment score of 0.91 beat Harrow's score of 0.81 indicating that SOPHiA GENETICS is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SOPHiA GENETICS
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Harrow
0 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Harrow has higher revenue and earnings than SOPHiA GENETICS. Harrow is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SOPHiA GENETICS$81.18M4.03-$79M-$0.52N/A
Harrow$272.30M4.56-$5.14M-$0.41N/A

Summary

Harrow beats SOPHiA GENETICS on 13 of the 16 factors compared between the two stocks.

How does SOPHiA GENETICS compare to WAVE Life Sciences?

SOPHiA GENETICS (NASDAQ:SOPH) and WAVE Life Sciences (NASDAQ:WVE) are both small-cap medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their institutional ownership, earnings, valuation, analyst recommendations, media sentiment, dividends, profitability and risk.

In the previous week, WAVE Life Sciences had 2 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 5 mentions for WAVE Life Sciences and 3 mentions for SOPHiA GENETICS. SOPHiA GENETICS's average media sentiment score of 0.91 beat WAVE Life Sciences' score of 0.32 indicating that SOPHiA GENETICS is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SOPHiA GENETICS
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
WAVE Life Sciences
0 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

31.6% of SOPHiA GENETICS shares are held by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are held by institutional investors. 4.9% of SOPHiA GENETICS shares are held by company insiders. Comparatively, 24.3% of WAVE Life Sciences shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

SOPHiA GENETICS has higher revenue and earnings than WAVE Life Sciences. SOPHiA GENETICS is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SOPHiA GENETICS$81.18M4.03-$79M-$0.52N/A
WAVE Life Sciences$42.73M25.94-$204.38M-$1.06N/A

SOPHiA GENETICS has a beta of 0.98, indicating that its stock price is 2% less volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.33, indicating that its stock price is 233% less volatile than the broader market.

SOPHiA GENETICS has a net margin of -44.48% compared to WAVE Life Sciences' net margin of -255.70%. WAVE Life Sciences' return on equity of -56.76% beat SOPHiA GENETICS's return on equity.

Company Net Margins Return on Equity Return on Assets
SOPHiA GENETICS-44.48% -62.74% -21.85%
WAVE Life Sciences -255.70%-56.76%-42.80%

SOPHiA GENETICS currently has a consensus price target of $7.50, suggesting a potential upside of 56.90%. WAVE Life Sciences has a consensus price target of $27.25, suggesting a potential upside of 373.09%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, analysts clearly believe WAVE Life Sciences is more favorable than SOPHiA GENETICS.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SOPHiA GENETICS
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
WAVE Life Sciences
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.87

Summary

WAVE Life Sciences beats SOPHiA GENETICS on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SOPH and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SOPH vs. The Competition

MetricSOPHiA GENETICSMEDICAL INFO SYS IndustryMedical SectorNASDAQ Exchange
Market Cap$327.36M$1.55B$6.25B$12.42B
Dividend YieldN/AN/A2.69%5.29%
P/E Ratio-9.1977.6222.2924.19
Price / Sales4.0323.43581.44138.36
Price / CashN/A23.1542.3157.88
Price / Book6.934.779.846.72
Net Income-$79M-$54.76M$3.57B$337.19M
7 Day Performance-5.91%-0.78%-1.17%0.48%
1 Month Performance-10.15%4.20%3.84%5.06%
1 Year Performance57.76%-3.40%27.39%34.27%

SOPHiA GENETICS Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SOPH
SOPHiA GENETICS
2.3684 of 5 stars
$4.78
-3.2%
$7.50
+56.9%
+69.8%$327.36M$81.18MN/A520
SEPN
Septerna
2.3438 of 5 stars
$30.65
+8.1%
$43.13
+40.7%
+201.5%$1.28B$45.95MN/AN/A
AVBP
ArriVent BioPharma
2.5133 of 5 stars
$27.94
+4.5%
$43.13
+54.3%
+36.0%$1.24BN/AN/A40
COAG
Hemab Therapeutics
4.8106 of 5 stars
$27.84
+7.5%
$41.75
+50.0%
N/A$1.23BN/AN/A72
HROW
Harrow
4.4484 of 5 stars
$34.17
+3.5%
$69.43
+103.2%
+9.6%$1.23B$268.68MN/A180

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This page (NASDAQ:SOPH) was last updated on 6/3/2026 by MarketBeat.com Staff.
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