Cogent Biosciences (COGT) Stock Price, News & Analysis

Company Overview

Cogent Biosciences is a clinical-stage biopharmaceutical company focused on the discovery and development of small-molecule therapies that modulate the tumor microenvironment. The company’s research centers on targeting colony-stimulating factor 1 receptor (CSF1R), a key regulator of tumor-associated macrophages that can promote tumor growth and immune evasion. By selectively inhibiting CSF1R, Cogent Biosciences aims to restore immune surveillance and enhance the efficacy of existing cancer treatments.

The company’s lead asset is an orally bioavailable CSF1R inhibitor that has advanced into early-stage clinical trials for various solid tumors. Preclinical studies have demonstrated the candidate’s ability to deplete immunosuppressive macrophages within the tumor microenvironment, resulting in antitumor activity as a monotherapy and in combination with checkpoint inhibitors. Cogent continues to explore additional novel small molecules that can influence immune-regulatory pathways in oncology.

Founded in 2016 and headquartered in Cambridge, Massachusetts, Cogent Biosciences completed its initial public offering in 2020 and maintains operations in key U.S. research hubs. The company leverages collaborative partnerships with academic institutions and contract research organizations to advance its pipeline efficiently. While most of its clinical programs are currently being evaluated in North America, Cogent is positioned to pursue international trial sites as it progresses through later-stage development.

Under the leadership of President and Chief Executive Officer Daniel Welch, Cogent Biosciences is guided by a management team with deep experience in oncology drug development, translational research, and regulatory strategy. The company’s board and scientific advisory committees include experts in immuno-oncology and precision medicine, supporting its mission to bring novel targeted therapies to patients with unmet medical needs.

Key Stats

• Today's Range: $15.72 to $17.15
• 50-Day Range: $11.71 to $16.57
• 52-Week Range: $3.72 to $17.15
• Volume: 2.79 million shs
• Average Volume: 1.98 million shs
• Market Capitalization: $1.81 billion
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $20.83
• Consensus Rating: Moderate Buy

Cogent Biosciences Stock Analysis - MarketRank™

Cogent Biosciences scored higher than 44% of companies evaluated by MarketBeat, and ranked 621st out of 941 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.4 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

Cogent Biosciences has received a consensus rating of Moderate Buy. The company's average rating score is 2.71, and is based on 7 buy ratings, 4 hold ratings, and 1 sell rating.

Upside Potential

Cogent Biosciences has a consensus price target of $20.83, representing about 31.4% upside from its current price of $15.86.

Amount of Analyst Coverage

Cogent Biosciences has been the subject of 6 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Cogent Biosciences are expected to grow in the coming year, from ($2.42) to ($2.20) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Cogent Biosciences is -8.91, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Cogent Biosciences is -8.91, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Cogent Biosciences has a P/B Ratio of 12.02. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 1.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

14.94% of the outstanding shares of Cogent Biosciences have been sold short.

Short Interest Ratio / Days to Cover

Cogent Biosciences has a short interest ratio ("days to cover") of 8.6.

Change versus previous month

Short interest in Cogent Biosciences has recently increased by 13.08%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Cogent Biosciences does not currently pay a dividend.

Dividend Growth

Cogent Biosciences does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

14.94% of the outstanding shares of Cogent Biosciences have been sold short.

Short Interest Ratio / Days to Cover

Cogent Biosciences has a short interest ratio ("days to cover") of 8.6.

Change versus previous month

Short interest in Cogent Biosciences has recently increased by 13.08%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 2.3 / 5
• News Sentiment: 0.19

News Sentiment

Cogent Biosciences has a news sentiment score of 0.19. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.50 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 10 news articles for Cogent Biosciences this week, compared to 4 articles on an average week.

Search Interest

20 people have searched for COGT on MarketBeat in the last 30 days. This is an increase of 150% compared to the previous 30 days.

Company Ownership

• Score: 0.0 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Cogent Biosciences insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 7.29% of the stock of Cogent Biosciences is held by insiders.

COGT Stock Analysis - Frequently Asked Questions

How have COGT shares performed this year?

Cogent Biosciences' stock was trading at $7.80 at the start of the year. Since then, COGT shares have increased by 103.3% and is now trading at $15.86.

How were Cogent Biosciences' earnings last quarter?

Cogent Biosciences, Inc. (NASDAQ:COGT) announced its quarterly earnings data on Tuesday, August, 5th. The technology company reported ($0.53) EPS for the quarter, topping analysts' consensus estimates of ($0.55) by $0.02.

Who are Cogent Biosciences' major shareholders?

Top institutional shareholders of Cogent Biosciences include Assenagon Asset Management S.A. (0.51%), Voya Investment Management LLC (0.05%) and CWM LLC.
View institutional ownership trends.

How do I buy shares of Cogent Biosciences?

Shares of COGT stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Cogent Biosciences own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Cogent Biosciences investors own include Visa (V), Tesla (TSLA), Meta Platforms (META), JPMorgan Chase & Co. (JPM), Netflix (NFLX), NVIDIA (NVDA) and Advanced Micro Devices (AMD).

Company Calendar

• Last Earnings: 8/05/2025
• Today: 10/21/2025
• Next Earnings (Estimated): 11/11/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:COGT
• CIK: 1622229
• Web: www.cogint.com
• Phone: (617) 945-5576
• Fax: N/A
• Employees: 80
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Cogent Biosciences: $20.83
• High Price Target: $44.00
• Low Price Target: $9.00
• Potential Upside/Downside: +31.4%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.71
• Research Coverage: 14 Analysts

Profitability

• EPS (Trailing Twelve Months): ($1.78)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$255.86 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -223.82%
• Return on Assets: -89.44%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 4.19
• Quick Ratio: 4.19

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $1.32 per share
• Price / Book: 12.02

Miscellaneous

• Outstanding Shares: 113,860,000
• Free Float: 105,556,000
• Market Cap: $1.81 billion
• Optionable: Optionable
• Beta: 0.30