NASDAQ:CRBU Caribou Biosciences (CRBU) Stock Price, News & Analysis $1.95 +0.02 (+1.04%) Closing price 04:00 PM EasternExtended Trading$1.94 -0.01 (-0.56%) As of 07:49 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Caribou Biosciences Stock (NASDAQ:CRBU) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Caribou Biosciences alerts:Sign Up Key Stats Today's Range$1.93▼$1.9750-Day Range$1.71▼$2.3652-Week Range$0.73▼$3.54Volume977,090 shsAverage Volume1.50 million shsMarket Capitalization$192.43 millionP/E RatioN/ADividend YieldN/APrice Target$8.00Consensus RatingModerate Buy Company Overview Caribou Biosciences, Inc. is a clinical-stage biopharmaceutical company that leverages its proprietary CRISPR-Cas gene-editing platform to develop transformative cell therapies and in vivo treatments for a range of cancers and genetic diseases. The company’s core technology enables precise modification of cellular genomes, allowing the design of engineered T-cell and NK-cell therapies aimed at improving safety, efficacy and persistence in patients with hematologic and solid tumor malignancies. Alongside its oncology portfolio, Caribou is advancing in vivo editing programs targeting monogenic disorders, with initiatives in areas such as Duchenne muscular dystrophy and familial amyloidosis. Established in 2011 and headquartered in Berkeley, California, Caribou Biosciences was co-founded by Nobel laureate Jennifer Doudna, one of the pioneers of CRISPR gene-editing technology. The company holds licenses to foundational CRISPR intellectual property from the University of California, enabling continuous innovation in genome engineering. Since completing its initial public offering in August 2021, Caribou has focused on progressing its clinical pipeline and expanding manufacturing capabilities to support its growing roster of investigational therapies. Caribou’s leadership team combines deep expertise in molecular biology, clinical development and manufacturing scale-up, supported by an advisory board that includes leading figures in biotechnology and medicine. The company has established strategic collaborations with pharmaceutical and academic partners to advance its research programs and accelerate clinical translation. Caribou continues to conduct trials across multiple regions, aiming to bring its next-generation cell therapies and in vivo gene-editing treatments to patients worldwide.AI Generated. May Contain Errors. Read More Caribou Biosciences Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks38th Percentile Overall ScoreCRBU MarketRank™: Caribou Biosciences scored higher than 38% of companies evaluated by MarketBeat, and ranked 638th out of 857 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.0 / 5Analyst RatingModerate Buy Consensus RatingCaribou Biosciences has received a consensus rating of Moderate Buy. The company's average rating score is 2.75, and is based on 1 strong buy rating, 2 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialCaribou Biosciences has a consensus price target of $8.00, representing about 310.3% upside from its current price of $1.95.Amount of Analyst CoverageCaribou Biosciences has only been the subject of 3 research reports in the past 90 days.Read more about Caribou Biosciences' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Caribou Biosciences are expected to decrease in the coming year, from ($1.30) to ($1.48) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Caribou Biosciences is -1.23, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Caribou Biosciences is -1.23, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioCaribou Biosciences has a P/B Ratio of 1.49. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Caribou Biosciences' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted7.64% of the float of Caribou Biosciences has been sold short.Short Interest Ratio / Days to CoverCaribou Biosciences has a short interest ratio ("days to cover") of 5.49.Change versus previous monthShort interest in Caribou Biosciences has recently increased by 4.57%, indicating that investor sentiment is decreasing. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldCaribou Biosciences does not currently pay a dividend.Dividend GrowthCaribou Biosciences does not have a long track record of dividend growth. News and Social Media1.3 / 5News SentimentN/A News Coverage This WeekMarketBeat has tracked 1 news article for Caribou Biosciences this week, compared to 2 articles on an average week.Search Interest9 people have searched for CRBU on MarketBeat in the last 30 days. This is an increase of 50% compared to the previous 30 days.MarketBeat Follows2 people have added Caribou Biosciences to their MarketBeat watchlist in the last 30 days. This is an increase of 100% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Caribou Biosciences insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $35,454.00 in company stock.Percentage Held by Insiders8.54% of the stock of Caribou Biosciences is held by insiders.Percentage Held by Institutions77.51% of the stock of Caribou Biosciences is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Caribou Biosciences' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. CRBU Stock News HeadlinesCaribou Biosciences to Participate in the BofA Securities 2026 Health Care ConferenceMay 5 at 4:05 PM | globenewswire.comCaribou Biosciences (CRBU) price target decreased by 22.79% to 8.92April 28, 2026 | msn.comLouis Navellier: My #1 AI stock for 2026 (name & ticker inside)Louis Navellier's Stock Grader system helped him flag Nvidia before its 82,000% run and has identified the top S&P 500 stock for 12 years running—and today, he's giving away his #1 AI stock pick for 2026, free. This company's sales are up 28% year over year, it holds over 30,000 patents in wireless and video technology, and it just earned an A-rating in his proprietary Stock Grader system that has cost him $9 million to build and maintain.May 6 at 1:00 AM | InvestorPlace (Ad)Caribou rises on FDA RMAT designation for CAR-T therapyApril 1, 2026 | seekingalpha.comCaribou Biosciences Announces the FDA Granted Regenerative Medicine Advanced Therapy (RMAT) Designation to CB-011, an Allogeneic Anti-BCMA CAR-T Cell TherapyMarch 31, 2026 | globenewswire.comLeerink Partners Remains a Buy on Caribou Biosciences (CRBU)March 11, 2026 | theglobeandmail.comClear Street Sticks to Their Buy Rating for Caribou Biosciences (CRBU)March 11, 2026 | theglobeandmail.comDrug Pricing Reforms Threaten Caribou Biosciences’ Future Margins and Market AccessMarch 7, 2026 | tipranks.comSee More Headlines CRBU Stock Analysis - Frequently Asked Questions How have CRBU shares performed this year? Caribou Biosciences' stock was trading at $1.59 at the start of the year. Since then, CRBU stock has increased by 22.6% and is now trading at $1.95. How were Caribou Biosciences' earnings last quarter? Caribou Biosciences, Inc. (NASDAQ:CRBU) announced its quarterly earnings results on Thursday, March, 5th. The company reported ($0.28) earnings per share for the quarter, beating the consensus estimate of ($0.33) by $0.05. The firm had revenue of $3.94 million for the quarter, compared to analyst estimates of $1.96 million. Caribou Biosciences had a negative net margin of 1,327.40% and a negative trailing twelve-month return on equity of 78.40%. When did Caribou Biosciences IPO? Caribou Biosciences (CRBU) raised $285 million in an initial public offering on Wednesday, July 21st 2021. The company issued 19,000,000 shares at $14.00-$16.00 per share. Who are Caribou Biosciences' major shareholders? Top institutional investors of Caribou Biosciences include Westmount Partners LLC (0.02%). Insiders that own company stock include Rachel E Haurwitz, Barbara G Mcclung, Ruhi Ahmad Khan, Timothy P Kelly, Tina M Albertson and Sriram Ryali. View institutional ownership trends. How do I buy shares of Caribou Biosciences? Shares of CRBU stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Caribou Biosciences own? Based on aggregate information from My MarketBeat watchlists, some other companies that Caribou Biosciences investors own include Voyager Therapeutics (VYGR), American Water Works (AWK), The RMR Group (RMR), Waste Connections (WCN), AUO (AUOTY), DiamondRock Hospitality (DRH) and iShares Micro-Cap ETF (IWC). Company Calendar Last Earnings3/05/2026Today5/06/2026Bank of America Global Healthcare Conference 20265/13/2026Next Earnings (Estimated)5/14/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (2m+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 CRBU's financial health is in the Green zone, according to TradeSmith. CRBU has been in this zone for over 2 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:CRBU CIK1619856 Webcariboubio.com Phone510-982-6030FaxN/AEmployees100Year Founded2012Price Target and Rating Average Price Target for Caribou Biosciences$8.00 High Price Target$9.00 Low Price Target$7.00 Potential Upside/Downside+310.3%Consensus RatingModerate Buy Rating Score (0-4)2.75 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($1.59) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$148.12 million Net Margins-1,327.40% Pretax Margin-1,332.33% Return on Equity-78.40% Return on Assets-58.68% Debt Debt-to-Equity RatioN/A Current Ratio5.71 Quick Ratio5.71 Sales & Book Value Annual Sales$11.16 million Price / Sales17.24 Cash FlowN/A Price / Cash FlowN/A Book Value$1.31 per share Price / Book1.49Miscellaneous Outstanding Shares98,680,000Free Float90,255,000Market Cap$192.43 million OptionableOptionable Beta2.27 Social Links 7 Stocks to Ride The A.I. 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