NASDAQ:GPCR Structure Therapeutics (GPCR) Stock Price, News & Analysis $22.31 -1.60 (-6.69%) Closing price 10/13/2026 04:00 PM EasternExtended Trading$22.31 0.00 (0.00%) As of 10/13/2026 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Structure Therapeutics Stock (NASDAQ:GPCR) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Structure Therapeutics alerts:Sign Up Key Stats Today's Range$22.10▼$24.0350-Day Range$22.31▼$54.7052-Week Range$22.10▼$94.90Volume1.43 million shsAverage Volume1.48 million shsMarket Capitalization$1.55 billionP/E RatioN/ADividend YieldN/APrice Target$110.91Consensus RatingModerate Buy Company Overview Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company developing oral small-molecule medicines for chronic metabolic and cardiopulmonary diseases. The company uses structure-based drug discovery and related technologies to identify therapies intended to address conditions with significant unmet medical needs. Its lead product candidate is GSBR-1290, an investigational oral small-molecule agonist of the glucagon-like peptide-1 (GLP-1) receptor being developed for obesity and type 2 diabetes. Unlike injectable GLP-1 therapies, the candidate is designed as an oral treatment. Structure Therapeutics is also advancing additional discovery and development programs targeting metabolic, cardiovascular and pulmonary diseases. Structure Therapeutics operates internationally, with activities and personnel in the United States and China. The company was formerly known as Shouyao Holdings and became a publicly traded company on the Nasdaq under the symbol GPCR in 2023. Its scientific and executive leadership includes experienced drug-discovery and biotechnology professionals, supported by a team focused on translating structural biology into potential medicines.AI Generated. May Contain Errors. Read More Structure Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks47th Percentile Overall ScoreGPCR MarketRank™: 2.328983788055 of 5 starsStructure Therapeutics scored higher than 47% of companies evaluated by MarketBeat, and ranked 575th out of 877 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.2 / 5Analyst RatingModerate Buy Consensus RatingStructure Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.82, and is based on 2 strong buy ratings, 12 buy ratings, 1 hold rating, and 2 sell ratings.Upside PotentialStructure Therapeutics has a consensus price target of $110.91, representing about 397.1% upside from its current price of $22.31.Amount of Analyst CoverageStructure Therapeutics has only been the subject of 4 research reports in the past 90 days.Read more about Structure Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Structure Therapeutics are expected to decrease in the coming year, from ($1.87) to ($2.09) per share.Price to Book Value per Share RatioStructure Therapeutics has a P/B Ratio of 0.89. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Structure Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted11.46% of the float of Structure Therapeutics has been sold short.Short Interest Ratio / Days to CoverStructure Therapeutics has a short interest ratio ("days to cover") of 5.17.Change versus previous monthShort interest in Structure Therapeutics has recently increased by 14.16%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldStructure Therapeutics does not currently pay a dividend.Dividend GrowthStructure Therapeutics does not have a long track record of dividend growth. News and Social Media1.8 / 5News Sentiment-0.09 News SentimentStructure Therapeutics has a news sentiment score of -0.09. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.70 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Structure Therapeutics this week, compared to 4 articles on an average week.Search Interest8 people have searched for GPCR on MarketBeat in the last 30 days. This is an increase of 33% compared to the previous 30 days.MarketBeat FollowsOnly 1 people have added Structure Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days. Company Ownership0.9 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Structure Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders5.50% of the stock of Structure Therapeutics is held by insiders.Percentage Held by Institutions91.78% of the stock of Structure Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Structure Therapeutics' insider trading history. Receive GPCR Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Structure Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. GPCR Stock News HeadlinesStructure Therapeutics (NASDAQ:GPCR) Stock Rating Cut to Strong Sell at Wall Street ZenOctober 3, 2026 | americanbankingnews.comGPCR Share News TodaySeptember 24, 2026 | uk.investing.comWhy major institutions are piling into this digital asset nowBlackRock, JPMorgan, Goldman Sachs, and Fidelity are reportedly accumulating a scarce blockchain asset - one that gets burned with every transaction on what analysts are calling America's new financial grid. The Nasdaq has received SEC approval to move stocks onto blockchain rails, and BlackRock CEO Larry Fink dedicated his entire 2026 annual letter to this infrastructure shift. Blockchain analyst Andy Howard is calling this asset 'Digital Oil' - and says institutional buyers are already positioned. | Awesomely (Ad)Structure Therapeutics (GPCR) Gains Fresh Obesity Trial Backing Following Data That Keeps Valuation In FocusSeptember 22, 2026 | finance.yahoo.comStructure Therapeutics Inc ADR (GPCR)September 19, 2026 | za.investing.comStructure Therapeutics Inc. (GPCR) Presents at Morgan Stanley 24th Annual Global Healthcare Conference TranscriptSeptember 16, 2026 | seekingalpha.comStructure Therapeutics (GPCR): Will Repeat Dosing Confirm Its 3.3% Weight-Loss Signal?September 10, 2026 | insidermonkey.comStructure Therapeutics Inc. (GPCR) Discusses Positive Clinical Data Updates for Oral Small Molecule Amylin and GLP-1 Programs in Chronic Weight Management - SlideshowSeptember 9, 2026 | seekingalpha.comSee More Headlines GPCR Stock Analysis - Frequently Asked Questions How have GPCR shares performed this year? Structure Therapeutics' stock was trading at $69.55 at the beginning of the year. Since then, GPCR stock has decreased by 67.9% and is now trading at $22.31. How were Structure Therapeutics' earnings last quarter? Structure Therapeutics Inc. Sponsored ADR (NASDAQ:GPCR) posted its quarterly earnings results on Thursday, August, 6th. The company reported ($0.49) earnings per share for the quarter, missing analysts' consensus estimates of ($0.39) by $0.10. When did Structure Therapeutics IPO? Structure Therapeutics (GPCR) raised $150 million in an initial public offering on Friday, February 3rd 2023. The company issued 10,740,000 shares at a price of $13.00-$15.00 per share. How do I buy shares of Structure Therapeutics? Shares of GPCR stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Structure Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Structure Therapeutics investors own include NVIDIA (NVDA), Micron Technology (MU), Viking Therapeutics (VKTX), SLB (SLB), SoundHound AI (SOUN), Palo Alto Networks (PANW) and Advanced Micro Devices (AMD). Company Calendar Last Earnings8/06/2026Today10/13/2026Next Earnings (Estimated)11/05/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (4m+) 1-Year History Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 GPCR's financial health is in the Red zone, according to TradeSmith. GPCR has been in this zone for over 4 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Pharmaceuticals Sub-IndustryPharmaceuticals Current SymbolNASDAQ:GPCR CIK1888886 Webwww.structuretx.com Phone628-229-9277FaxN/AEmployees281Year FoundedN/APrice Target and Rating Average Price Target for Structure Therapeutics$110.91 High Price Target$145.00 Low Price Target$70.00 Potential Upside/Downside+397.1%Consensus RatingModerate Buy Rating Score (0-4)2.82 Research Coverage17 Analysts Profitability EPS (Trailing Twelve Months)($1.00) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$141.20 million Net MarginsN/A Pretax MarginN/A Return on Equity-25.56% Return on Assets-24.31% Debt Debt-to-Equity RatioN/A Current Ratio20.75 Quick Ratio20.75 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$24.99 per share Price / Book0.89Miscellaneous Outstanding Shares69,620,000Free Float65,792,000Market Cap$1.55 billion OptionableOptionable Beta-1.30 10 Stocks Powering The Next AI Boom The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation. 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