NASDAQ:GYRE Gyre Therapeutics (GYRE) Stock Price, News & Analysis $6.73 -0.01 (-0.15%) Closing price 04:00 PM EasternExtended Trading$6.72 -0.01 (-0.07%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOwnershipSEC FilingsShort Interest About Gyre Therapeutics Stock (NASDAQ:GYRE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Gyre Therapeutics alerts:Sign Up Key Stats Today's Range$6.73▼$6.9550-Day Range$5.64▼$7.3452-Week Range$5.44▼$9.42Volume69,802 shsAverage Volume86,960 shsMarket Capitalization$750.46 millionP/E RatioN/ADividend YieldN/APrice Target$16.00Consensus RatingReduce Company Overview Gyre Therapeutics, Inc. is a clinical-stage biotechnology company focused on discovering and developing small-molecule therapies that target lipid biology to treat a range of metabolic, inflammatory and neurodegenerative diseases. The company’s proprietary platform combines lipidomic profiling with drug discovery tools to identify compounds that selectively modulate membrane lipid composition and restore normal protein function in disease-relevant cells. Gyre’s preclinical pipeline includes programs in nonalcoholic steatohepatitis (NASH), Alzheimer’s disease and autoimmune conditions, reflecting its strategy of applying a unified lipid-targeted approach across multiple therapeutic areas. By leveraging its platform to validate novel targets and generate lead candidates, the company aims to address unmet medical needs where dysregulated lipid environments drive disease progression. Headquartered in South San Francisco, California, Gyre Therapeutics was founded in 2021 and completed its initial public offering on the Nasdaq Global Market under the ticker symbol GYRE in mid-2023. Operating primarily in the United States, the company collaborates with academic researchers and industry partners to advance its discovery efforts. Through its innovative focus on membrane biochemistry, Gyre seeks to build a diversified portfolio of first-in-class small-molecule therapies.AI Generated. May Contain Errors. Read More Gyre Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks40th Percentile Overall ScoreGYRE MarketRank™: Gyre Therapeutics scored higher than 40% of companies evaluated by MarketBeat, and ranked 673rd out of 905 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.2 / 5Analyst RatingReduce Consensus RatingGyre Therapeutics has received a consensus rating of Reduce. The company's average rating score is 1.67, and is based on no strong buy ratings, 1 buy rating, no hold ratings, and 2 sell ratings.Upside PotentialGyre Therapeutics has a consensus price target of $16.00, representing about 137.4% upside from its current price of $6.74.Amount of Analyst CoverageGyre Therapeutics has only been the subject of 2 research reports in the past 90 days.Read more about Gyre Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Gyre Therapeutics are expected to grow in the coming year, from ($0.61) to ($0.47) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Gyre Therapeutics is -32.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Gyre Therapeutics is -32.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioGyre Therapeutics has a P/B Ratio of 4.55. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Gyre Therapeutics' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted1.69% of the float of Gyre Therapeutics has been sold short.Short Interest Ratio / Days to CoverGyre Therapeutics has a short interest ratio ("days to cover") of 34.43, which indicates bearish sentiment.Change versus previous monthShort interest in Gyre Therapeutics has recently decreased by 2.09%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldGyre Therapeutics does not currently pay a dividend.Dividend GrowthGyre Therapeutics does not have a long track record of dividend growth. News and Social Media2.6 / 5News Sentiment1.20 News SentimentGyre Therapeutics has a news sentiment score of 1.20. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.86 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Gyre Therapeutics this week, compared to 2 articles on an average week. Company Ownership0.6 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Gyre Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders9.50% of the stock of Gyre Therapeutics is held by insiders.Percentage Held by Institutions23.99% of the stock of Gyre Therapeutics is held by institutions.Read more about Gyre Therapeutics' insider trading history. Receive GYRE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Gyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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GYRE Stock News HeadlinesGyre Therapeutics to Participate in Upcoming September Investor ConferencesSeptember 3, 2026 | globenewswire.comAnalysts Are Bullish on These Healthcare Stocks: Gyre Therapeutics (GYRE), Align Tech (ALGN)August 12, 2026 | theglobeandmail.comTicker Revealed: Pre-IPO Access to "Next Elon Musk" CompanyWe’ve found The Next Elon Musk… and what we believe to be the next Tesla. It’s already racked up $26 billion in government contracts. Peter Thiel just bet $1 Billion on it.September 11 at 1:00 AM | Banyan Hill Publishing (Ad)Gyre Therapeutics Reports Second Quarter 2026 and Year-to-Date Financial Results and Provides Business UpdateAugust 7, 2026 | globenewswire.comGyre Therapeutics Appoints Three New Members to its Board of DirectorsJuly 16, 2026 | globenewswire.comGyre Therapeutics Shareholders Approve Directors and Governance MeasuresJune 16, 2026 | tipranks.comGyre Therapeutics Announces NMPA Acceptance of New Drug Application for F351 (hydronidone) for CHB-Induced Liver Fibrosis TreatmentMay 12, 2026 | globenewswire.comGyre Therapeutics Reports First Quarter 2026 Results and Provides Business UpdateMay 7, 2026 | globenewswire.comSee More Headlines GYRE Stock Analysis - Frequently Asked Questions How have GYRE shares performed this year? Gyre Therapeutics' stock was trading at $7.06 at the start of the year. Since then, GYRE stock has decreased by 4.5% and is now trading at $6.74. How were Gyre Therapeutics' earnings last quarter? Gyre Therapeutics, Inc. (NASDAQ:GYRE) issued its quarterly earnings results on Friday, August, 7th. The company reported ($0.12) earnings per share for the quarter, missing analysts' consensus estimates of ($0.06) by $0.06. The company had revenue of $29.11 million for the quarter, compared to analyst estimates of $26.49 million. Gyre Therapeutics had a negative net margin of 15.47% and a negative trailing twelve-month return on equity of 6.57%. Who are Gyre Therapeutics' major shareholders? Gyre Therapeutics' top institutional investors include BlackRock Inc. (0.89%), Bank of New York Mellon Corp (0.06%), Deutsche Bank AG (0.02%) and Bank of America Corp DE (0.01%). Insiders that own company stock include Songjiang Ma, Ying Luo, Weiguo Ye and Nassim Usman. View institutional ownership trends. How do I buy shares of Gyre Therapeutics? Shares of GYRE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Gyre Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Gyre Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Advanced Micro Devices (AMD), Netflix (NFLX), Broadcom (AVGO), Palo Alto Networks (PANW) and Invesco QQQ (QQQ). Company Calendar Last Earnings8/07/2026Today9/11/2026Morgan Stanley 24th Annual Global Healthcare Conference9/16/2026Next Earnings (Estimated)11/06/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (17m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 GYRE's financial health is in the Red zone, according to TradeSmith. GYRE has been in this zone for over 17 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Pharmaceuticals Sub-IndustryPharmaceuticals Current SymbolNASDAQ:GYRE Previous SymbolNASDAQ:GYRE CIK1124105 Webwww.catalystbiosciences.com Phone(619) 949-3681Fax336-480-2107Employees40Year FoundedN/APrice Target and Rating Average Price Target for Gyre Therapeutics$16.00 High Price Target$16.00 Low Price Target$16.00 Potential Upside/Downside+137.7%Consensus RatingReduce Rating Score (0-4)1.67 Research Coverage3 Analysts Profitability EPS (Trailing Twelve Months)($0.21) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$5.03 million Net Margins-15.47% Pretax Margin-10.30% Return on Equity-6.57% Return on Assets-5.35% Debt Debt-to-Equity RatioN/A Current Ratio4.26 Quick Ratio3.86 Sales & Book Value Annual Sales$109.82 million Price / Sales6.83 Cash Flow$0.22 per share Price / Cash Flow31.28 Book Value$1.48 per share Price / Book4.55Miscellaneous Outstanding Shares111,510,000Free Float100,917,000Market Cap$750.46 million OptionableNo Data Beta1.92 Options Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. 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