Kezar Life Sciences (KZR) Stock Price, News & Analysis

Company Overview

Kezar Life Sciences is a clinical-stage biopharmaceutical company headquartered in Redwood City, California, dedicated to developing novel therapies in immunology and oncology. Founded in 2012, Kezar combines cutting-edge science with targeted drug discovery to address serious autoimmune and inflammatory diseases as well as certain cancers. The company leverages proprietary platforms and deep expertise in small-molecule therapeutics to produce selective inhibitors that modulate immune pathways.

The company’s lead candidate, KZR-616, is a first-in-class selective inhibitor of the immunoproteasome, designed to treat systemic lupus erythematosus (SLE) and other autoimmune conditions. KZR-616 has advanced through Phase 1 clinical trials, demonstrating favorable safety and pharmacodynamic profiles. Beyond immunoproteasome inhibition, Kezar is advancing complementary research programs targeting alternative immune-regulatory enzymes, with the goal of expanding its pipeline into additional indications such as myositis and inflammatory bowel disease.

Kezar conducts its research and development activities across facilities in the United States and Europe, collaborating with academic institutions, contract research organizations and patient advocacy groups. The company maintains strategic partnerships to accelerate clinical development and broaden access to patients worldwide. Kezar’s multidisciplinary team of scientists, clinicians and regulatory experts drives a pipeline that spans discovery through late-stage clinical development, with a focus on precision-based immunotherapies.

Under the leadership of President and CEO Dr. Vic T. Zhou, Kezar is committed to translating scientific innovation into transformative medicines. The executive team brings decades of experience in drug development, regulatory strategy and commercialization, positioning the company to advance its pipeline toward regulatory milestones, strategic collaborations and market authorization in key global territories.

Key Stats

• Today's Range: $4.45 to $4.70
• 50-Day Range: $3.83 to $4.79
• 52-Week Range: $3.62 to $9.18
• Volume: 24,966 shs
• Average Volume: 52,011 shs
• Market Capitalization: $33.46 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $39.50
• Consensus Rating: Hold

Kezar Life Sciences Stock Analysis - MarketRank™

Kezar Life Sciences scored higher than 83% of companies evaluated by MarketBeat, and ranked 197th out of 920 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.2 / 5
• Analyst Rating: Hold

Consensus Rating

Kezar Life Sciences has received a consensus rating of Hold. The company's average rating score is 2.33, and is based on 1 buy rating, 2 hold ratings, and no sell ratings.

Amount of Analyst Coverage

Kezar Life Sciences has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Kezar Life Sciences are expected to decrease in the coming year, from ($4.39) to ($8.31) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Kezar Life Sciences is -0.42, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Kezar Life Sciences is -0.42, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Kezar Life Sciences has a P/B Ratio of 0.29. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

0.85% of the float of Kezar Life Sciences has been sold short.

Short Interest Ratio / Days to Cover

Kezar Life Sciences has a short interest ratio ("days to cover") of 1.5, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Kezar Life Sciences has recently increased by 7.52%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Kezar Life Sciences does not currently pay a dividend.

Dividend Growth

Kezar Life Sciences does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.6 / 5
• Environmental Score: -0.85

Percentage of Shares Shorted

0.85% of the float of Kezar Life Sciences has been sold short.

Short Interest Ratio / Days to Cover

Kezar Life Sciences has a short interest ratio ("days to cover") of 1.5, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Kezar Life Sciences has recently increased by 7.52%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 0.6 / 5
• News Sentiment: -1.00

News Sentiment

Kezar Life Sciences has a news sentiment score of -1.00. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.56 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 2 news articles for Kezar Life Sciences this week, compared to 1 article on an average week.

Company Ownership

• Score: 3.3 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Kezar Life Sciences insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $3,531.00 in company stock.

Percentage Held by Insiders

10.40% of the stock of Kezar Life Sciences is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

67.90% of the stock of Kezar Life Sciences is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

KZR Stock Analysis - Frequently Asked Questions

How have KZR shares performed this year?

Kezar Life Sciences' stock was trading at $6.72 at the start of the year. Since then, KZR shares have decreased by 31.8% and is now trading at $4.58.

How were Kezar Life Sciences' earnings last quarter?

Kezar Life Sciences, Inc. (NASDAQ:KZR) issued its earnings results on Tuesday, May, 13th. The company reported ($2.27) earnings per share (EPS) for the quarter, beating the consensus estimate of ($2.56) by $0.29.

When did Kezar Life Sciences' stock split?

Shares of Kezar Life Sciences reverse split on the morning of Wednesday, October 30th 2024.The 1-10 reverse split was announced on Monday, October 28th 2024. The number of shares owned by shareholders was adjusted after the closing bell on Tuesday, October 29th 2024. An investor that had 100 shares of stock prior to the reverse split would have 10 shares after the split.

When did Kezar Life Sciences IPO?

Kezar Life Sciences (KZR) raised $70 million in an initial public offering (IPO) on Thursday, June 21st 2018. The company issued 4,700,000 shares at a price of $14.00-$16.00 per share. Jefferies, Cowen, Wells Fargo Securities and William Blair acted as the underwriters for the IPO.

How do I buy shares of Kezar Life Sciences?

Shares of KZR stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Kezar Life Sciences own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Kezar Life Sciences investors own include Predictive Oncology (POAI), Ford Motor (F), JPMorgan Chase & Co. (JPM), Wells Fargo & Company (WFC), Bank of America (BAC), Abbott Laboratories (ABT) and Zomedica (ZOM).

Company Calendar

• Last Earnings: 5/13/2025
• Today: 7/09/2025
• Next Earnings (Estimated): 8/12/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:KZR
• CIK: 1645666
• Web: www.kezarlifesciences.com
• Phone: (650) 822-5600
• Fax: N/A
• Employees: 60
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Kezar Life Sciences: $39.50
• High Price Target: $70.00
• Low Price Target: $9.00
• Potential Upside/Downside: +762.4%
• Consensus Rating: Hold
• Rating Score (0-4): 2.33
• Research Coverage: 3 Analysts

Profitability

• EPS (Trailing Twelve Months): ($10.82)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$83.74 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -61.15%
• Return on Assets: -50.27%

Debt

• Debt-to-Equity Ratio: 0.04
• Current Ratio: 7.09
• Quick Ratio: 7.09

Sales & Book Value

• Annual Sales: $7 million
• Price / Sales: 4.78
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $16.02 per share
• Price / Book: 0.29

Miscellaneous

• Outstanding Shares: 7,310,000
• Free Float: 6,546,000
• Market Cap: $33.48 million
• Optionable: Not Optionable
• Beta: 0.60