Madrigal Pharmaceuticals (MDGL) Short Interest Ratio & Short Volume $451.53 +1.89 (+0.42%) As of 10:44 AM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Madrigal Pharmaceuticals Short Interest DataMadrigal Pharmaceuticals (MDGL) has a short interest of 4.14 million shares. This marks a 2.22% increase in short interest from the previous month. The short interest ratio (days to cover) is 10.9, indicating that it would take 10.9 days of the average trading volume of 373,073 shares to cover all short positions.Current Short Interest4,140,000 sharesPrevious Short Interest4,050,000 sharesChange Vs. Previous Month+2.22%Dollar Volume Sold Short$1.76 billionShort Interest Ratio10.9 Days to CoverLast Record DateSeptember 15, 2025Outstanding Shares22,200,000 sharesPercentage of Shares Shorted18.65%Today's Trading Volume16,378 sharesAverage Trading Volume373,073 sharesToday's Volume Vs. Average4% Short Selling Madrigal Pharmaceuticals? Sign up to receive the latest short interest report for Madrigal Pharmaceuticals and its competitors with MarketBeat's FREE newsletter. Email Address Get Report View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartMDGL Short Interest Over TimeMDGL Days to Cover Over TimeMDGL Percentage of Float Shorted Over Time Madrigal Pharmaceuticals Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 9/15/20254,140,000 shares $1.76 billion +2.2%N/A10.9 $425.60 8/31/20254,050,000 shares $1.77 billion +6.9%23.2%10.7 $437.85 8/15/20253,790,000 shares $1.40 billion -4.8%N/A10.2 $369.84 7/31/20253,980,000 shares $1.20 billion +5.0%22.8%11.5 $302.51 7/15/20253,790,000 shares $1.18 billion -4.5%N/A11.2 $311.14 6/30/20253,970,000 shares $1.20 billion -4.3%22.8%11.9 $302.64 6/15/20254,150,000 shares $1.23 billion +6.7%23.8%12.6 $295.57 5/31/20253,890,000 shares $1.08 billion -2.8%23.1%11.6 $276.70 5/15/20254,000,000 shares $1.17 billion -2.4%23.8%10.7 $291.82 4/30/20254,100,000 shares $1.37 billion +1.7%N/A11 $333.91 Get the Latest News and Ratings for MDGL and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Madrigal Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 4/15/20254,030,000 shares $1.29 billion +0.8%23.9%10.7 $321.10 3/31/20254,000,000 shares $1.32 billion -2.2%23.8%9.9 $331.23 3/15/20254,090,000 shares $1.42 billion +9.1%24.3%10.1 $348.35 2/28/20253,750,000 shares $1.28 billion -1.3%22.3%9.3 $341.27 2/15/20253,800,000 shares $1.28 billion -4.5%22.6%9.8 $337.20 1/31/20253,980,000 shares $1.33 billion -2.5%N/A9.9 $334.80 1/15/20254,080,000 shares $1.12 billion -0.7%N/A8.6 $274.41 12/31/20244,110,000 shares $1.27 billion -13.1%N/A9.8 $308.57 12/15/20244,730,000 shares $1.44 billion +10.5%N/A11.2 $304.50 11/30/20244,280,000 shares $1.40 billion -3.4%N/A10.6 $328.19 11/15/20244,430,000 shares $1.28 billion -2.2%N/A11.3 $288.58 10/31/20244,530,000 shares $1.17 billion +11.9%N/A13.1 $259.34 10/15/20244,050,000 shares $875.49 million +4.9%N/A15.1 $216.17 9/30/20243,860,000 shares $819.17 million +3.5%N/A13.8 $212.22 9/15/20243,730,000 shares $901.91 million -0.8%N/A13.5 $241.80 8/31/20243,760,000 shares $929.21 million +0.3%N/A11.5 $247.13 8/15/20243,750,000 shares $916.88 million +1.9%N/A9.5 $244.50 7/31/20243,680,000 shares $1.05 billion -10.5%N/A8.6 $284.66 7/15/20244,110,000 shares $1.15 billion +0.7%N/A9.1 $279.95 6/30/20244,080,000 shares $1.14 billion -7.9%N/A9.1 $280.16 6/15/20244,430,000 shares $1.23 billion -15.3%N/A9.5 $277.59 5/31/20245,230,000 shares $1.24 billion +25.4%N/A9.4 $236.16 5/15/20244,170,000 shares $882.91 million +4.8%N/A8.1 $211.73 4/30/20243,980,000 shares $812.00 million +16.7%N/A6.9 $204.02 4/15/20243,410,000 shares $788.97 million +1.5%N/A5.9 $231.37 3/31/20243,360,000 shares $897.25 million +3.1%N/A6 $267.04 3/15/20243,260,000 shares $881.41 million -5.8%20.2%5.9 $270.37 2/29/20243,460,000 shares $817.25 million +2.1%21.4%7.3 $236.20 2/15/20243,390,000 shares $753.33 million +8.0%21.1%7.6 $222.22 1/31/20243,140,000 shares $680.47 million -5.1%19.5%7.2 $216.71 1/15/20243,310,000 shares $780.50 million +1.9%21.1%8.6 $235.80 12/31/20233,250,000 shares $751.99 million +5.9%20.7%7.9 $231.38 12/15/20233,070,000 shares $727.99 million -11.5%19.5%6.7 $237.13 11/30/20233,470,000 shares $705.45 million +0.3%24.4%7.1 $203.30 11/15/20233,460,000 shares $559.41 million +1.5%24.3%7.7 $161.68 10/31/20233,410,000 shares $448.01 million +13.3%24.7%8.2 $131.38 10/15/20233,010,000 shares $422.51 million +13.6%21.8%7.6 $140.37 9/30/20232,650,000 shares $387.01 million +24.4%19.2%7.4 $146.04 9/15/20232,130,000 shares $374.65 million +8.7%16.5%6.3 $175.89 8/31/20231,960,000 shares $352.80 million +8.3%15.2%6.3 $180.00 8/15/20231,810,000 shares $315.25 million -1.1%14.0%5.7 $174.17 7/31/20231,830,000 shares $375.70 million -3.2%13.8%5.3 $205.30 7/15/20231,890,000 shares $426.71 million +7.4%14.3%5.4 $225.77 6/30/20231,760,000 shares $406.56 million +10.0%13.3%4.7 $231.00 6/15/20231,600,000 shares $408.85 million +10.3%12.1%4.7 $255.53 5/31/20231,450,000 shares $403.69 million +15.1%10.4%3.9 $278.41 5/15/20231,260,000 shares $365.77 million -8.7%9.0%3.1 $290.29 4/30/20231,380,000 shares $430.56 million -6.8%10.0%3.3 $312.00 4/15/20231,480,000 shares $354.89 million +19.4%10.8%3.7 $239.79 3/31/20231,240,000 shares $300.40 million +3.3%9.2%3.1 $242.26 3/15/20231,200,000 shares $286.57 million +16.5%8.7%2.3 $238.81 2/28/20231,030,000 shares $279.14 million +9.2%7.4%1.6 $271.01 2/15/2023942,900 shares $266.14 million 0.0%7.2%1.5 $282.26 1/31/2023943,300 shares $271.91 million -3.3%7.2%1.6 $288.25 1/15/2023975,300 shares $292.57 million -12.9%7.5%1.6 $299.98 12/30/20221,120,000 shares $325.08 million -52.7%9.0%1.9 $290.25 12/15/20222,370,000 shares $149.07 million +9.7%19.1%4.3 $62.90 11/30/20222,160,000 shares $151.44 million +3.9%17.4%7.3 $70.11 11/15/20222,080,000 shares $146.68 million +14.3%16.8%7.9 $70.52 10/31/20221,820,000 shares $128.89 million +17.4%14.7%7.4 $70.82 10/15/20221,550,000 shares $100.27 million +1.3%12.5%6.6 $64.69 9/30/20221,530,000 shares $99.43 million +2.7%12.4%7.2 $64.99 9/15/20221,490,000 shares $103.70 million +1.4%12.1%7.4 $69.60 8/31/20221,470,000 shares $106.02 million -4.6%11.9%7.8 $72.12 8/15/20221,540,000 shares $118.13 million -3.8%12.5%8.6 $76.71 7/31/20221,600,000 shares $100.51 million +3.2%12.9%8.4 $62.82 7/15/20221,550,000 shares $107.24 million -4.3%12.5%8.1 $69.19 6/30/20221,620,000 shares $115.96 million -2.4%13.1%8.1 $71.58 6/15/20221,660,000 shares $112.71 million +3.8%13.4%8.6 $67.90 5/31/20221,600,000 shares $106.22 million -5.3%12.9%8.5 $66.39 5/15/20221,690,000 shares $111.08 million -2.9%13.6%8.8 $65.73 4/30/20221,740,000 shares $121.80 million +1.8%14.0%8.2 $70.00 4/15/20221,710,000 shares $135.89 million -5.5%13.8%7.3 $79.47 3/31/20221,810,000 shares $177.60 million -9.1%14.6%7.8 $98.12 3/15/20221,990,000 shares $179.10 million +0.5%16.0%8.5 $90.00 2/28/20221,980,000 shares $183.84 million -1.5%16.0%8.1 $92.85 2/15/20222,010,000 shares $180.72 million +12.3%16.2%8.4 $89.91 1/31/20221,790,000 shares $103.07 million +19.3%14.4%8.5 $57.58 1/15/20221,500,000 shares $117.68 million +8.7%12.1%9.4 $78.45 12/31/20211,380,000 shares $116.94 million -6.8%11.1%9.6 $84.74 12/15/20211,480,000 shares $110.82 million +7.3%11.9%10.8 $74.88 11/30/20211,380,000 shares $114.14 million +2.2%12.0%12 $82.71 11/15/20211,350,000 shares $122.00 million -3.6%11.8%12.7 $90.37 10/29/20211,400,000 shares $108.85 million +3.7%12.2%13.3 $77.75 10/15/20211,350,000 shares $116.33 million -6.9%12.1%13.5 $86.17 9/30/20211,450,000 shares $115.70 million No Change13.0%14.1 $79.79 9/15/20211,450,000 shares $115.10 million -7.1%13.0%11.9 $79.38 8/31/20211,560,000 shares $129.09 million -5.5%14.0%12.2 $82.75 8/13/20211,650,000 shares $140.02 million +3.1%14.8%10.9 $84.86 7/30/20211,600,000 shares $139.71 million -4.2%14.4%10.4 $87.32 7/15/20211,670,000 shares $157.95 million No Change15.0%11 $94.58 6/30/20211,670,000 shares $162.67 million -5.1%15.0%10.9 $97.41 6/15/20211,760,000 shares $185.66 million -7.9%15.8%12.4 $105.49 5/28/20211,910,000 shares $214.49 million -7.3%17.2%14.1 $112.30 5/14/20212,060,000 shares $271.12 million +1.0%18.9%16.5 $131.61 4/30/20212,040,000 shares $280.68 million -8.5%18.7%14.8 $137.59 4/15/20212,230,000 shares $269.70 million -5.1%21.8%12.3 $120.94 3/31/20212,350,000 shares $273.80 million -4.5%23.4%12.7 $116.51 3/15/20212,460,000 shares $289.89 million -7.5%24.5%12.4 $117.84 2/26/20212,660,000 shares $327.34 million -4.0%26.5%13.5 $123.06 2/12/20212,770,000 shares $334.67 million +5.3%28.6%14.4 $120.82 1/29/20212,630,000 shares $304.11 million -8.4%26.0%13.7 $115.63 1/15/20212,870,000 shares $327.18 million +4.7%28.4%17.9 $114.00 12/31/20202,740,000 shares $304.47 million +12.3%27.1%19.3 $111.12 12/15/20202,440,000 shares $294.58 million -2.4%24.2%17.2 $120.73 11/30/20202,500,000 shares $297.78 million +5.5%24.8%16.9 $119.11 11/15/20202,370,000 shares $303.57 million -4.4%23.5%16.3 $128.09 10/30/20202,480,000 shares $318.23 million +0.8%24.6%18.5 $128.32 10/15/20202,460,000 shares $312.94 million No Change24.4%19.1 $127.21 MDGL Short Interest - Frequently Asked Questions What is Madrigal Pharmaceuticals' current short interest? Short interest is the volume of Madrigal Pharmaceuticals shares that have been sold short but have not yet been closed out or covered. As of September 15th, investors have sold 4,140,000 shares of MDGL short. Learn More on Madrigal Pharmaceuticals' current short interest. What is a good short interest ratio for Madrigal Pharmaceuticals? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. MDGL shares currently have a short interest ratio of 11.0. Learn More on Madrigal Pharmaceuticals's short interest ratio. Which institutional investors are shorting Madrigal Pharmaceuticals? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Madrigal Pharmaceuticals: Nomura Holdings Inc., Group One Trading LLC, 683 Capital Management LLC, Jane Street Group LLC, Walleye Capital LLC, Garda Capital Partners LP, and Twin Tree Management LP. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. Is Madrigal Pharmaceuticals' short interest increasing or decreasing? Madrigal Pharmaceuticals saw a increase in short interest in the month of September. As of September 15th, there was short interest totaling 4,140,000 shares, an increase of 2.2% from the previous total of 4,050,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Madrigal Pharmaceuticals' short interest compare to its competitors? Here is how the short interest of companies in the industry of "biotechnology" compare to Madrigal Pharmaceuticals: Biogen Inc. (3.51%), United Therapeutics Corporation (6.35%), Incyte Corporation (4.51%), Neurocrine Biosciences, Inc. (4.15%), Exelixis, Inc. (6.75%), BioMarin Pharmaceutical Inc. (3.81%), Ionis Pharmaceuticals, Inc. (7.57%), Exact Sciences Corporation (4.27%), Halozyme Therapeutics, Inc. (10.18%), Repligen Corporation (6.66%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Corporation ($8.81 billion), Canadian Natural Resources Limited ($5.82 billion), Reddit Inc. ($5.19 billion), Coinbase Global, Inc. ($4.52 billion), Robinhood Markets, Inc. ($4.30 billion), Charter Communications, Inc. ($3.75 billion), CoreWeave Inc. ($3.66 billion), Seagate Technology Holdings PLC ($3.57 billion), Live Nation Entertainment, Inc. ($3.33 billion), and Rocket Lab Corporation ($3.26 billion). View all of the most shorted stocks. What does it mean to sell short Madrigal Pharmaceuticals stock? Short selling MDGL is an investing strategy that aims to generate trading profit from Madrigal Pharmaceuticals as its price is falling. MDGL shares are trading up $0.50 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Madrigal Pharmaceuticals? A short squeeze for Madrigal Pharmaceuticals occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of MDGL, which in turn drives the price of the stock up even further. How often is Madrigal Pharmaceuticals' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including MDGL, twice per month. The most recent reporting period available is September, 15 2025. 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