OPKO Health (OPK) Institutional Ownership $1.30 -0.03 (-2.26%) Closing price 04:00 PM EasternExtended Trading$1.32 +0.02 (+1.54%) As of 07:07 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for OPKO Health (NASDAQ:OPK)CurrentInstitutional OwnershipPercentage64.63%Number ofInstitutional Buyers(last 12 months)83TotalInstitutional Inflows(last 12 months)$121.41MNumber ofInstitutional Sellers(last 12 months)43TotalInstitutional Outflows(last 12 months)$21.60M Get OPK Insider Trade Alerts Want to know when executives and insiders are buying or selling OPKO Health stock? 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Email Address Skip Chart & View Institutional Buying and Selling Data OPK Institutional Buying and Selling by Quarter OPKO Health Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails5/16/2025 Caxton Associates LLP78,128$130K0.0%N/A0.010% 5/16/2025 Voleon Capital Management LP 27,225$45K0.0%N/A0.003% 5/16/2025 Goldman Sachs Group Inc.4,001,214$6.64M0.0%+4.2%0.505% 5/16/2025 Millennium Management LLC6,386,911$10.60M0.0%+39.2%0.805% 5/16/2025 AQR Capital Management LLC1,608,906$2.67M0.0%+466.7%0.203% 5/16/2025 AWM Investment Company Inc.1,850,000$3.07M0.4%+42.3%0.233% 5/15/2025 Cubist Systematic Strategies LLC119,223$198K0.0%+2,369.9%0.015% 5/15/2025 Graham Capital Management L.P.1,810,392$3.01M0.1%-214.7%0.228% 5/15/2025 Sculptor Capital LP12,717,400$21.11M0.4%N/A1.604% 5/14/2025 Ieq Capital LLC183,363$304K0.0%+417.7%0.023% Get the Latest News and Ratings for OPK and Related StocksEnter your email address below to receive the latest news and analysts' ratings for OPKO Health and its competitors with MarketBeat's FREE daily newsletter. 5/14/2025 MetLife Investment Management LLC164,230$273K0.0%-18.8%0.021% 5/14/2025 Jump Financial LLC49,070$81K0.0%N/A0.006% 5/14/2025 GM Advisory Group LLC20,000$33K0.0%N/A0.003% 5/14/2025 Quantbot Technologies LP210,079$349K0.0%N/A0.026% 5/13/2025 American Century Companies Inc.92,785$154K0.0%N/A0.012% 5/13/2025 Tejara Capital Ltd860,344$1.43M0.6%-29.8%0.108% 5/12/2025 Nuveen LLC1,376,881$2.29M0.0%N/A0.174% 5/12/2025 Invesco Ltd.1,623,600$2.70M0.0%+4.4%0.205% 5/12/2025 Connor Clark & Lunn Investment Management Ltd.201,345$334K0.0%+802.9%0.025% 5/12/2025 Swiss National Bank661,155$1.10M0.0%-3.5%0.083% 5/12/2025 Y.D. More Investments Ltd1,772,947$2.97M0.3%+27.0%0.224% 5/9/2025 Deutsche Bank AG281,647$468K0.0%-9.1%0.036% 5/9/2025 Headlands Technologies LLC52,149$87K0.0%N/A0.007% 5/9/2025 Charles Schwab Investment Management Inc.2,741,986$4.55M0.0%-21.6%0.346% 5/9/2025 Vanguard Group Inc.29,500,071$48.97M0.0%+1.0%3.720% 5/8/2025 XTX Topco Ltd309,290$513K0.0%+58.8%0.039% 5/8/2025 GSA Capital Partners LLP1,343,701$2.23M0.2%+24.2%0.169% 5/7/2025 Inspire Advisors LLC47,130$78K0.0%N/A0.006% 5/6/2025 Oak Thistle LLC15,636$26K0.0%N/A0.002% 5/5/2025 Private Advisor Group LLC55,301$92K0.0%+56.7%0.008% 5/1/2025 CWM LLC74,503$124K0.0%+961.9%0.011% 4/30/2025 Cerity Partners LLC21,528$36K0.0%N/A0.003% 4/29/2025 Capital Advisors Inc. OK350,000$581K0.0%+133.3%0.052% 4/28/2025 Teacher Retirement System of Texas83,766$139K0.0%N/A0.012% 4/22/2025 PFG Investments LLC1,217,360$2.02M0.1%+4.9%0.181% 4/17/2025 Exchange Traded Concepts LLC338,948$563K0.0%-3.7%0.050% 4/16/2025 Wealth Enhancement Advisory Services LLC74,706$124K0.0%+158.4%0.011% 4/15/2025 Assenagon Asset Management S.A.935,100$1.56M0.0%+9.1%0.139% 4/15/2025 SG Americas Securities LLC352,276$585K0.0%N/A0.052% 4/14/2025 Pallas Capital Advisors LLC25,851$43K0.0%N/A0.004% Washington Is Broke—and Eyeing Your Savings Next (Ad)Washington is running out of money…And guess where they'll look next? When governments go broke, they take from the people. It's happened before, and it's happening again. The Department of Justice just admitted that cash isn't legally YOUR property.Get your free guide now by clicking here >>4/8/2025 Rhumbline Advisers490,279$814K0.0%-5.5%0.073% 3/17/2025 Wealth Enhancement Advisory Services LLC28,908$42K0.0%+75.3%0.004% 2/17/2025 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC753,380$1.11M0.0%+24.5%0.110% 2/17/2025 Two Sigma Advisers LP381,197$560K0.0%+2.3%0.056% 2/17/2025 Two Sigma Investments LP1,647,567$2.42M0.0%+136.1%0.241% 2/17/2025 Point72 Asia Singapore Pte. Ltd.41,589$61K0.0%-55.1%0.006% 2/17/2025 ProShare Advisors LLC91,730$135K0.0%+49.0%0.013% 2/17/2025Nuveen Asset Management LLC1,432,404$2.11M0.0%+42.3%0.210% 2/17/2025 Numerai GP LLC139,755$205K0.1%N/A0.020% 2/17/2025 Millennium Management LLC4,588,526$6.75M0.0%+85.3%0.672% 2/17/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.186,783$275K0.0%+4.5%0.027% 2/17/2025 Lazard Asset Management LLC2,548,667$3.75M0.0%+143.6%0.373% 2/17/2025 Deutsche Bank AG309,867$456K0.0%+48.3%0.045% 2/17/2025 Brevan Howard Capital Management LP66,282$97K0.0%-35.2%0.010% 2/17/2025 Bank of America Corp DE581,582$855K0.0%+94.7%0.085% 2/17/2025 BNP Paribas Financial Markets51,849$76K0.0%-79.0%0.008% 2/14/2025 Mercer Global Advisors Inc. ADV43,167$63K0.0%+105.6%0.006% 2/14/2025 Comerica Bank106,369$156K0.0%+18.2%0.016% 2/14/2025 Northern Trust Corp3,697,774$5.44M0.0%+4.7%0.542% 2/14/2025 Two Sigma Securities LLC75,782$111K0.0%-33.6%0.011% 2/14/2025 Voya Investment Management LLC1,255,034$1.85M0.0%-39.4%0.184% 2/14/2025 Price T Rowe Associates Inc. MD455,521$670K0.0%+4.3%0.067% 2/14/2025 Tower Research Capital LLC TRC17,823$26K0.0%-88.8%0.003% 2/14/2025 MetLife Investment Management LLC202,165$297K0.0%+40.8%0.030% 2/14/2025 Dimensional Fund Advisors LP2,268,666$3.34M0.0%-2.6%0.332% 2/13/2025 Altshuler Shaham Ltd1,411,019$2.08M0.1%N/A0.207% 2/13/2025 Marshall Wace LLP921,487$1.36M0.0%+856.5%0.135% 2/13/2025 Zacks Investment Management33,300$49K0.0%N/A0.005% 2/13/2025 XTX Topco Ltd194,804$286K0.0%+79.3%0.029% 2/13/2025 Barclays PLC916,368$1.35M0.0%+68.7%0.134% 2/13/2025 Raymond James Financial Inc.150,670$221K0.0%N/A0.022% 2/13/2025 Renaissance Technologies LLC145,977$215K0.0%-68.2%0.021% 2/13/2025 Legal & General Group Plc370,438$545K0.0%-16.9%0.054% 2/13/2025 Invesco Ltd.1,554,489$2.29M0.0%-74.2%0.228% 2/13/2025 Wells Fargo & Company MN229,262$337K0.0%+14.9%0.034% 2/12/2025 ExodusPoint Capital Management LP173,700$255K0.0%N/A0.025% 2/12/2025 Geode Capital Management LLC8,385,218$12.33M0.0%+0.1%1.229% 2/12/2025 Alliancebernstein L.P.375,320$552K0.0%-22.9%0.055% 2/12/2025 X Square Capital LLC161,726$238K0.1%-4.6%0.024% 2/12/2025 Norges Bank1,127,468$1.66M0.0%N/A0.165% 2/11/2025 Prudential Financial Inc.31,356$46K0.0%-69.0%0.005% 2/11/2025 Corebridge Financial Inc.161,934$238K0.0%-7.0%0.024% 2/11/2025 Vanguard Group Inc.29,206,331$42.93M0.0%0.0%4.279% 2/11/2025 LPL Financial LLC33,132$49K0.0%-68.2%0.005% 2/11/2025 KLP Kapitalforvaltning AS74,000$109K0.0%N/A0.011% 2/10/2025 Tejara Capital Ltd1,225,650$1.80M1.2%+11.3%0.180% 2/10/2025 Cibc World Markets Corp30,482$45K0.0%N/A0.004% 2/10/2025 Catalyst Funds Management Pty Ltd61,600$91K0.0%N/A0.009% 2/10/2025 Essential Planning LLC.331,175$506K0.0%N/A0.049% 2/7/2025 HighTower Advisors LLC39,991$59K0.0%-14.7%0.006% Washington Is Broke—and Eyeing Your Savings Next (Ad)Washington is running out of money…And guess where they'll look next? When governments go broke, they take from the people. It's happened before, and it's happening again. The Department of Justice just admitted that cash isn't legally YOUR property.Get your free guide now by clicking here >>2/6/2025 Raymond James Financial Inc.150,670$221K0.0%N/A0.022% 2/6/2025 Charles Schwab Investment Management Inc.3,497,406$5.14M0.0%-17.0%0.512% 2/4/2025 Bank of New York Mellon Corp1,024,907$1.51M0.0%-3.7%0.150% 2/4/2025 Y Intercept Hong Kong Ltd69,591$102K0.0%N/A0.010% 2/3/2025 Ieq Capital LLC35,419$52K0.0%N/A0.005% 1/30/2025 Rhumbline Advisers518,823$763K0.0%-5.1%0.076% 1/29/2025 Capital Advisors Inc. OK150,000$220K0.0%N/A0.022% 1/27/2025 Choreo LLC37,086$55K0.0%-49.0%0.005% 1/27/2025 Y.D. More Investments Ltd1,395,768$2.06M0.2%-18.6%0.205% 1/22/2025 PFG Investments LLC1,160,885$1.71M0.1%+9.4%0.170% (Data available from 1/1/2016 forward) OPK Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of OPK shares? During the previous two years, 144 institutional investors and hedge funds held shares of OPKO Health. The most heavily invested institutionals were Rubric Capital Management LP ($72.57M), Vanguard Group Inc. ($48.97M), Sculptor Capital LP ($21.11M), State Street Corp ($12.99M), Geode Capital Management LLC ($12.33M), Millennium Management LLC ($10.60M), and Goldman Sachs Group Inc. ($6.64M).Learn more on OPK's institutional investors. What percentage of OPKO Health stock is owned by institutional investors? 64.63% of OPKO Health stock is owned by institutional investors. Learn more on OPK's institutional investor holdings. Which institutional investors have been buying OPKO Health stock? Of the 117 institutional investors that purchased OPKO Health stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Rubric Capital Management LP ($43.77M), Sculptor Capital LP ($12.72M), Invesco Ltd. ($3.94M), Millennium Management LLC ($3.91M), Graham Capital Management L.P. ($3.39M), Y.D. More Investments Ltd ($1.85M), and Lazard Asset Management LLC ($1.72M). How much institutional buying is happening at OPKO Health? Institutional investors have bought a total of 95,475,630 shares in the last 24 months. This purchase volume represents approximately $137.00M in transactions. Which OPKO Health major shareholders have been selling company stock? Of the 58 institutional investors that sold OPKO Health stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Vanguard Group Inc. ($10.26M), Invesco Ltd. ($4.48M), Oracle Investment Management Inc. ($4.03M), Charles Schwab Investment Management Inc. ($2.31M), Assenagon Asset Management S.A. ($1.89M), Renaissance Technologies LLC ($1.41M), and Numerai GP LLC ($1.02M). How much institutional selling is happening at OPKO Health? Institutional investors have sold a total of 31,989,965 shares in the last 24 months. This volume of shares sold represents approximately $45.67M in transactions. Related Companies BCRX Institutional Ownership LGND Institutional Ownership FOLD Institutional Ownership MNKD Institutional Ownership CLDX Institutional Ownership DVAX Institutional Ownership INVA Institutional Ownership NVAX Institutional Ownership GERN Institutional Ownership RGLS Institutional Ownership This page (NASDAQ:OPK) was last updated on 5/21/2025 by MarketBeat.com Staff From Our PartnersMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. 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