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Prelude Therapeutics (PRLD) 10K Form and Latest SEC Filings 2026

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$4.66 +0.02 (+0.43%)
Closing price 05/13/2026 04:00 PM Eastern
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Latest Prelude Therapeutics SEC Filings & Recent Activity

Prelude Therapeutics (NASDAQ:PRLD) has submitted 248+ documents to the U.S. Securities and Exchange Commission (SEC) since 2019. For investors, these filings are the primary source of verified financial data — covering everything from annual revenue and debt levels in the 10-K, to material business events in 8-K current reports, to insider buying and selling activity in Form 4 disclosures. The most recent filing was a Form 10-Q submitted on May 12, 2026.

Form 4
Prelude Therapeutics Inc Reports Ownership Change on Apr. 28, 2026

Form 4 filings disclose changes in stock ownership by company insiders, including purchases, sales, grants, and option exercises.

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8-K
Prelude Therapeutics Files Current Report on May. 12, 2026

An 8-K is filed when a material corporate event occurs, such as an acquisition, leadership change, or financial update.

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10-Q
Prelude Therapeutics Files Quarterly Report on May. 12, 2026

The 10-Q contains Prelude Therapeutics's unaudited quarterly financial statements, revenue, earnings updates, and cash flow changes between annual reports.

View earnings history

Prelude Therapeutics SEC Filing History

Browse Prelude Therapeutics' complete SEC filing history using the filters below. Filter by form type - 10-K, 10-Q, 8-K, Form 4, and more - or set a custom date range to find a filing.

DateFilerForm TypeView
05/12/2026 6:11 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
05/12/2026 6:19 AM
Prelude Therapeutics (1678660) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
04/28/2026 4:13 PM
Kolchinsky Peter (1384859) Reporting
Prelude Therapeutics (1678660) Issuer
RA Capital Healthcare Fund LP (1315082) Reporting
RA CAPITAL MANAGEMENT, L.P. (1346824) Reporting
Shah Rajeev M. (1619841) Reporting
Form 3
Initial statement of beneficial ownership of securities  
04/28/2026 4:14 PM
Kolchinsky Peter (1384859) Reporting
Prelude Therapeutics (1678660) Issuer
RA Capital Healthcare Fund LP (1315082) Reporting
RA CAPITAL MANAGEMENT, L.P. (1346824) Reporting
Shah Rajeev M. (1619841) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
04/28/2026 4:16 PM
Prelude Therapeutics (1678660) Subject
RA CAPITAL MANAGEMENT, L.P. (1346824) Filed by
Form SCHEDULE 13G
04/23/2026 7:42 PM
ORBIMED ADVISORS LLC (1055951) Filed by
Prelude Therapeutics (1678660) Subject
Form SCHEDULE 13D/A
04/23/2026 5:48 PM
ORBIMED ADVISORS LLC (1055951) Reporting
OrbiMed Capital GP VI LLC (1682115) Reporting
ORBIMED CAPITAL LLC (1157524) Reporting
OrbiMed Genesis GP LLC (1808744) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/23/2026 5:50 PM
Bonita David P (1572451) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/22/2026 3:15 PM
667, L.P. (1551139) Reporting
Baker Bros. Advisors (0) GP
BAKER BROS. ADVISORS LP (1263508) Reporting
Baker Brothers Life Sciences LP (1363364) Reporting
BAKER FELIX (1087940) Reporting
BAKER JULIAN (1087939) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/22/2026 3:22 PM
BAKER BROS. ADVISORS LP (1263508) Filed by
Prelude Therapeutics (1678660) Subject
Form SCHEDULE 13D/A
04/20/2026 5:16 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
04/15/2026 3:19 PM
Morris Charles Q (1489966) Reporting
Prelude Therapeutics (1678660) Issuer
Form 3
Initial statement of beneficial ownership of securities  
04/15/2026 6:41 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/19/2026 6:39 PM
Brusky Sean P. (1884733) Reporting
Prelude Therapeutics (1678660) Issuer
Form 3
Initial statement of beneficial ownership of securities  
03/12/2026 3:16 PM
Prelude Therapeutics (1678660) Filer
Form 424B5
03/12/2026 3:18 PM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/10/2026 7:40 AM
Prelude Therapeutics (1678660) Filer
Form S-8
Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans  
03/10/2026 7:17 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/10/2026 7:24 AM
Prelude Therapeutics (1678660) Filer
Form 10-K
Annual report pursuant to Section 13 or 15(d)  
02/13/2026 3:02 PM
Prelude Therapeutics (1678660) Subject
Vaddi Krishna (1824633) Filed by
Form SCHEDULE 13G/A
02/05/2026 3:10 PM
Prelude Therapeutics (1678660) Issuer
Vaddi Krishna (1824633) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/05/2026 3:11 PM
Lim Bryant David (1752888) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
02/05/2026 3:12 PM
Prelude Therapeutics (1678660) Issuer
Scherle Peggy (1824632) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/05/2026 3:14 PM
Combs Andrew (1825005) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
02/03/2026 8:11 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
01/09/2026 6:30 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
12/16/2025 11:15 PM
Prelude Therapeutics (1678660) Filer
Form EFFECT
11/12/2025 6:07 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
11/12/2025 6:15 AM
Prelude Therapeutics (1678660) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
11/07/2025 3:28 PM
Prelude Therapeutics (1678660) Issuer
Sandor Victor (1620368) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
11/04/2025 7:53 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
10/17/2025 6:40 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
10/07/2025 6:05 AM
Huang Jane (1683913) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
09/19/2025 6:41 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
08/14/2025 6:23 AM
Prelude Therapeutics (1678660) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
08/14/2025 6:07 AM
Prelude Therapeutics (1678660) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
07/08/2025 3:06 PM
Huang Jane (1683913) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/13/2025 4:21 PM
BAKER BROS. ADVISORS LP (1263508) Filed by
Prelude Therapeutics (1678660) Subject
Form SCHEDULE 13D/A
06/13/2025 3:43 PM
Prelude Therapeutics (1678660) Issuer
Scherer Paul C (2072453) Reporting
Form 3
Initial statement of beneficial ownership of securities  
06/13/2025 3:45 PM
667, L.P. (1551139) Reporting
Baker Bros. Advisors (0) GP
BAKER BROS. ADVISORS LP (1263508) Reporting
Baker Brothers Life Sciences LP (1363364) Reporting
BAKER FELIX (1087940) Reporting
BAKER JULIAN (1087939) Reporting
Prelude Therapeutics (1678660) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/13/2025 3:15 PM
Prelude Therapeutics (1678660) Issuer
Sandor Victor (1620368) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
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05/15/2025 4:20 PM
Prelude Therapeutics (1678660) Subject
Vaddi Krishna (1824633) Filed by
Form SCHEDULE 13G/A
(Data available from 1/1/2016 forward)

Prelude Therapeutics SEC Filings - Frequently Asked Questions

Prelude Therapeutics (PRLD) has submitted 248+ filings to the SEC since 2019. You can browse the complete history or filter by form type using the tools above.

Prelude Therapeutics's fiscal year ends on December 31. The company typically files its 10-K annual report by the end of February, covering the prior fiscal year's financial results.

The most recent filing was a Form 10-Q submitted on May 12, 2026. This was a quarterly financial update for 2025.

SEC Filing Types: 10-K, 10-Q, 8-K and More

SEC filings are legally required disclosures that public companies submit to the U.S. Securities and Exchange Commission. Unlike press releases or earnings call transcripts, these documents are filed under legal obligation — meaning the financial data they contain is audited, standardized, and subject to penalties if materially false. For investors, that makes SEC filings the most reliable primary source available for evaluating a company's true financial position.

Yes. All SEC filings are publicly available through the SEC's EDGAR database and on financial research platforms like MarketBeat. Companies are required by law to make these disclosures accessible to all investors — meaning retail investors have access to the same source documents as institutional analysts.

A 10-K is an annual report containing audited financial statements and a full review of the company's business — it is the most comprehensive filing a company makes each year. A 10-Q is a shorter, unaudited quarterly update filed three times per year between annual reports. Investors typically use the 10-K for deep fundamental analysis and the 10-Q to track whether the company is on pace with its guidance mid-year.

The most important filing for fundamental investors. Filed once per year, the 10-K contains audited financial statements, revenue and earnings trends, debt obligations, risk factors, and management's own assessment of the business. Reading the risk factors section and comparing year-over-year financials can reveal issues that don't show up in analyst summaries.

An unaudited financial update filed three times per year (the 10-K covers Q4). Investors use 10-Qs to track whether guidance is on pace, monitor changes in cash flow or inventory, and catch any mid-year shifts in business conditions before they become headline news.

Filed within four business days of a material event — earnings releases, merger announcements, executive departures, or major asset sales. Because 8-Ks are filed before media coverage catches up, they are often the fastest way to get unfiltered information directly from the company on market-moving events.

Filed within two business days whenever an executive or director buys or sells company stock. Insider purchases — especially large or clustered buys — are often interpreted as a signal of management confidence. Insider selling is more ambiguous but worth monitoring for patterns, particularly around lock-up expirations or ahead of major announcements.


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This page (NASDAQ:PRLD) was last updated on 5/14/2026 by MarketBeat.com Staff.
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