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Prelude Therapeutics (PRLD) Competitors

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$4.59 -0.08 (-1.71%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$4.55 -0.04 (-0.96%)
As of 09/11/2026 07:57 PM Eastern
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PRLD vs. NVAX, ANAB, FBRX, ALVO, and BCAX

Should you buy Prelude Therapeutics stock or one of its competitors? Prelude Therapeutics's main competitors and comparable companies include Novavax (NVAX), AnaptysBio (ANAB), Forte Biosciences (FBRX), Alvotech (ALVO), and Bicara Therapeutics (BCAX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Prelude Therapeutics compare to Novavax?

Novavax (NASDAQ:NVAX) and Prelude Therapeutics (NASDAQ:PRLD) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, media sentiment, dividends, profitability, valuation, earnings, risk and institutional ownership.

Novavax presently has a consensus price target of $14.00, indicating a potential upside of 48.62%. Prelude Therapeutics has a consensus price target of $7.67, indicating a potential upside of 67.03%. Given Prelude Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Prelude Therapeutics is more favorable than Novavax.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Novavax
2 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.33
Prelude Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Novavax has higher revenue and earnings than Prelude Therapeutics. Prelude Therapeutics is trading at a lower price-to-earnings ratio than Novavax, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Novavax$1.12B1.38$440.30M-$1.52N/A
Prelude Therapeutics$12.14M30.17-$99.50M-$0.73N/A

Novavax has a beta of 2.45, indicating that its share price is 145% more volatile than the broader market. Comparatively, Prelude Therapeutics has a beta of 0.97, indicating that its share price is 3% less volatile than the broader market.

53.0% of Novavax shares are held by institutional investors. Comparatively, 79.7% of Prelude Therapeutics shares are held by institutional investors. 1.6% of Novavax shares are held by company insiders. Comparatively, 49.2% of Prelude Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

In the previous week, Novavax had 6 more articles in the media than Prelude Therapeutics. MarketBeat recorded 13 mentions for Novavax and 7 mentions for Prelude Therapeutics. Novavax's average media sentiment score of 0.53 beat Prelude Therapeutics' score of 0.39 indicating that Novavax is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Novavax
3 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Prelude Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Prelude Therapeutics has a net margin of 0.00% compared to Novavax's net margin of -59.87%. Novavax's return on equity of -14.82% beat Prelude Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Novavax-59.87% -14.82% -13.35%
Prelude Therapeutics N/A -75.35%-44.39%

Summary

Novavax beats Prelude Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Prelude Therapeutics compare to AnaptysBio?

AnaptysBio (NASDAQ:ANAB) and Prelude Therapeutics (NASDAQ:PRLD) are both small-cap healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, earnings, risk, dividends, media sentiment, valuation, analyst recommendations and profitability.

AnaptysBio has higher revenue and earnings than Prelude Therapeutics. AnaptysBio is trading at a lower price-to-earnings ratio than Prelude Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AnaptysBio$234.60M6.80-$13.23M-$1.08N/A
Prelude Therapeutics$12.14M30.17-$99.50M-$0.73N/A

In the previous week, Prelude Therapeutics had 3 more articles in the media than AnaptysBio. MarketBeat recorded 7 mentions for Prelude Therapeutics and 4 mentions for AnaptysBio. AnaptysBio's average media sentiment score of 1.54 beat Prelude Therapeutics' score of 0.39 indicating that AnaptysBio is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
AnaptysBio
2 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Prelude Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Prelude Therapeutics has a net margin of 0.00% compared to AnaptysBio's net margin of -11.53%. AnaptysBio's return on equity of 0.00% beat Prelude Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
AnaptysBio-11.53% N/A -7.75%
Prelude Therapeutics N/A -75.35%-44.39%

AnaptysBio currently has a consensus target price of $79.85, indicating a potential upside of 48.22%. Prelude Therapeutics has a consensus target price of $7.67, indicating a potential upside of 67.03%. Given Prelude Therapeutics' higher possible upside, analysts clearly believe Prelude Therapeutics is more favorable than AnaptysBio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
AnaptysBio
1 Sell rating(s)
3 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.67
Prelude Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

79.7% of Prelude Therapeutics shares are held by institutional investors. 31.5% of AnaptysBio shares are held by insiders. Comparatively, 49.2% of Prelude Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

AnaptysBio has a beta of 0.71, suggesting that its stock price is 29% less volatile than the broader market. Comparatively, Prelude Therapeutics has a beta of 0.97, suggesting that its stock price is 3% less volatile than the broader market.

Summary

Prelude Therapeutics beats AnaptysBio on 9 of the 16 factors compared between the two stocks.

How does Prelude Therapeutics compare to Forte Biosciences?

Prelude Therapeutics (NASDAQ:PRLD) and Forte Biosciences (NASDAQ:FBRX) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their dividends, institutional ownership, earnings, valuation, media sentiment, profitability, analyst recommendations and risk.

Forte Biosciences has lower revenue, but higher earnings than Prelude Therapeutics. Forte Biosciences is trading at a lower price-to-earnings ratio than Prelude Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prelude Therapeutics$12.14M30.17-$99.50M-$0.73N/A
Forte BiosciencesN/AN/A-$69.38M-$4.65N/A

Prelude Therapeutics has a beta of 0.97, indicating that its stock price is 3% less volatile than the broader market. Comparatively, Forte Biosciences has a beta of 2.62, indicating that its stock price is 162% more volatile than the broader market.

In the previous week, Prelude Therapeutics had 6 more articles in the media than Forte Biosciences. MarketBeat recorded 7 mentions for Prelude Therapeutics and 1 mentions for Forte Biosciences. Prelude Therapeutics' average media sentiment score of 0.39 beat Forte Biosciences' score of 0.00 indicating that Prelude Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prelude Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Forte Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Prelude Therapeutics currently has a consensus target price of $7.67, indicating a potential upside of 67.03%. Forte Biosciences has a consensus target price of $71.67, indicating a potential downside of 6.91%. Given Prelude Therapeutics' stronger consensus rating and higher possible upside, research analysts plainly believe Prelude Therapeutics is more favorable than Forte Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prelude Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Forte Biosciences
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Prelude Therapeutics' return on equity of -75.35% beat Forte Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Prelude TherapeuticsN/A -75.35% -44.39%
Forte Biosciences N/A -94.82%-77.68%

79.7% of Prelude Therapeutics shares are held by institutional investors. Comparatively, 77.6% of Forte Biosciences shares are held by institutional investors. 49.2% of Prelude Therapeutics shares are held by insiders. Comparatively, 4.4% of Forte Biosciences shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Summary

Prelude Therapeutics beats Forte Biosciences on 12 of the 14 factors compared between the two stocks.

How does Prelude Therapeutics compare to Alvotech?

Alvotech (NASDAQ:ALVO) and Prelude Therapeutics (NASDAQ:PRLD) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their analyst recommendations, valuation, dividends, media sentiment, institutional ownership, profitability, earnings and risk.

Alvotech has a beta of 0.22, indicating that its share price is 78% less volatile than the broader market. Comparatively, Prelude Therapeutics has a beta of 0.97, indicating that its share price is 3% less volatile than the broader market.

In the previous week, Prelude Therapeutics had 5 more articles in the media than Alvotech. MarketBeat recorded 7 mentions for Prelude Therapeutics and 2 mentions for Alvotech. Alvotech's average media sentiment score of 1.84 beat Prelude Therapeutics' score of 0.39 indicating that Alvotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alvotech
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Prelude Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Alvotech currently has a consensus target price of $7.50, suggesting a potential upside of 41.78%. Prelude Therapeutics has a consensus target price of $7.67, suggesting a potential upside of 67.03%. Given Prelude Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Prelude Therapeutics is more favorable than Alvotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alvotech
2 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.25
Prelude Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Prelude Therapeutics has a net margin of 0.00% compared to Alvotech's net margin of -36.31%. Alvotech's return on equity of -11.92% beat Prelude Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Alvotech-36.31% -11.92% -11.73%
Prelude Therapeutics N/A -75.35%-44.39%

Alvotech has higher revenue and earnings than Prelude Therapeutics. Alvotech is trading at a lower price-to-earnings ratio than Prelude Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alvotech$588.90M2.71$27.92M-$0.61N/A
Prelude Therapeutics$12.14M30.17-$99.50M-$0.73N/A

79.7% of Prelude Therapeutics shares are held by institutional investors. 0.5% of Alvotech shares are held by company insiders. Comparatively, 49.2% of Prelude Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Summary

Prelude Therapeutics beats Alvotech on 9 of the 16 factors compared between the two stocks.

How does Prelude Therapeutics compare to Bicara Therapeutics?

Prelude Therapeutics (NASDAQ:PRLD) and Bicara Therapeutics (NASDAQ:BCAX) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, media sentiment, analyst recommendations, dividends, profitability, risk, institutional ownership and earnings.

Prelude Therapeutics presently has a consensus target price of $7.67, suggesting a potential upside of 67.03%. Bicara Therapeutics has a consensus target price of $32.64, suggesting a potential upside of 43.08%. Given Prelude Therapeutics' higher probable upside, equities analysts plainly believe Prelude Therapeutics is more favorable than Bicara Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prelude Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Bicara Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
2.80

Prelude Therapeutics has higher revenue and earnings than Bicara Therapeutics. Bicara Therapeutics is trading at a lower price-to-earnings ratio than Prelude Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prelude Therapeutics$12.14M30.17-$99.50M-$0.73N/A
Bicara TherapeuticsN/AN/A-$137.95M-$3.10N/A

In the previous week, Prelude Therapeutics had 1 more articles in the media than Bicara Therapeutics. MarketBeat recorded 7 mentions for Prelude Therapeutics and 6 mentions for Bicara Therapeutics. Bicara Therapeutics' average media sentiment score of 1.04 beat Prelude Therapeutics' score of 0.39 indicating that Bicara Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prelude Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Bicara Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prelude Therapeutics has a beta of 0.97, indicating that its stock price is 3% less volatile than the broader market. Comparatively, Bicara Therapeutics has a beta of -0.82, indicating that its stock price is 182% less volatile than the broader market.

79.7% of Prelude Therapeutics shares are owned by institutional investors. 49.2% of Prelude Therapeutics shares are owned by company insiders. Comparatively, 13.8% of Bicara Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Bicara Therapeutics' return on equity of -41.49% beat Prelude Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Prelude TherapeuticsN/A -75.35% -44.39%
Bicara Therapeutics N/A -41.49%-38.59%

Summary

Prelude Therapeutics beats Bicara Therapeutics on 9 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRLD and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRLD vs. The Competition

MetricPrelude TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$366.30M$3.85B$7.16B$12.85B
Dividend YieldN/A3.65%2.57%11.17%
P/E Ratio-6.2914.18274.9425.36
Price / Sales30.171,374.96685.44117.05
Price / CashN/A106.5076.6551.52
Price / Book4.2115.1210.336.20
Net Income-$99.50M-$22.86M$3.50B$358.50M
7 Day Performance-15.93%-4.34%-3.32%-2.35%
1 Month Performance-14.37%0.54%-0.53%-3.23%
1 Year Performance306.19%40.74%23.51%8.79%

Prelude Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRLD
Prelude Therapeutics
2.325 of 5 stars
$4.59
-1.7%
$7.67
+67.0%
+306.2%$366.30M$12.14MN/A120
NVAX
Novavax
2.0816 of 5 stars
$10.06
+7.3%
$14.00
+39.2%
+18.0%$1.66B$1.12BN/A1,990
ANAB
AnaptysBio
2.8385 of 5 stars
$55.85
-2.1%
$79.85
+43.0%
+130.2%$1.65B$234.60MN/A100
FBRX
Forte Biosciences
0.854 of 5 stars
$76.99
flat
$71.67
-6.9%
N/A$1.63BN/AN/A5
ALVO
Alvotech
3.1207 of 5 stars
$5.20
+0.1%
$7.50
+44.3%
-34.1%$1.57B$588.90MN/A1,460

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This page (NASDAQ:PRLD) was last updated on 9/13/2026 by MarketBeat.com Staff.
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